Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo

Neuroscience

Volumn 126, Issue 2, 2004, Pages 381-390

  Whitehead, K J ^a   Pearce, S M ^a   Walker, G ^b   Sundaram, H ^b   Hill, D ^b   Bowery, N G ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

aECF; artificial extracellular fluid; ASP; aspartate; central sensitisation; CIT; citrulline; GLU; glutamate; GLY; glycine; glycine transporter; glycine transporter type 1; GlyT 1; GlyT 2; microdialysis; nitric oxide synthase; wind up

Indexed keywords

1 (2 TRIFLUOROMETHYLPHENYL)IMIDAZOLE; 4 AMINOBUTYRIC ACID; 4 BENZYLOXY 3,5 DIMETHOXY N [1 (DIMETHYLAMINOCYCLOPENTYL)METHYL]BENZAMIDE; 7 CHLOROKYNURENIC ACID; AMINO ACID TRANSPORTER; ASPARTIC ACID; CITRULLINE; DIZOCILPINE; GLUTAMIC ACID; GLYCINE TRANSPORTER 1; GLYCINE TRANSPORTER 2; HALOTHANE; IMIDAZOLE DERIVATIVE; INHIBITOR PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL N [3 [(4 TRIFLUOROMETHYL)PHENOXY] 3 PHENYLPROPYL]GLYCINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; ORG 24598; ORG 25543; STRYCHNINE; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; LUMBAR SPINAL CORD; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; SPINAL CORD; SYNAPSE;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; MALE; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 2942644495     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.04.006     Document Type: Article

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