-
1
-
-
0030292721
-
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130
-
Fukada, T.; Hibi, M.; Yamanaka, Y.; Takahashi-Tezuka, M.; Fujitani, Y.; Yamaguchi, T.; Nakajima, K.; Hirano, T. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis. Immunity 1996, 5, 449-460.
-
(1996)
Involvement of STAT3 In Anti-apoptosis. Immunity
, vol.5
, pp. 449-460
-
-
Fukada, T.1
Hibi, M.2
Yamanaka, Y.3
Takahashi-Tezuka, M.4
Fujitani, Y.5
Yamaguchi, T.6
Nakajima, K.7
Hirano, T.8
-
2
-
-
0031806534
-
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase
-
Takahashi-Tezuka, M.; Yoshida, Y.; Fukada, T.; Ohtani, T.; Yamanaka, Y.; Nishida, K.; Nakajima, K.; Hibi, M.; Hirano, T. Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase. Mol. Cell Biol. 1998, 18, 4109-4117.
-
(1998)
Mol. Cell Biol
, vol.18
, pp. 4109-4117
-
-
Takahashi-Tezuka, M.1
Yoshida, Y.2
Fukada, T.3
Ohtani, T.4
Yamanaka, Y.5
Nishida, K.6
Nakajima, K.7
Hibi, M.8
Hirano, T.9
-
3
-
-
2342565881
-
Advances in protein kinase B signalling
-
Brazil, D.P.; Yang, Z.-Z.; Hemmings, B.A. Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem. Sci. 2004, 29, 233-242.
-
(2004)
AKTion On Multiple Fronts. Trends Biochem. Sci
, vol.29
, pp. 233-242
-
-
Brazil, D.P.1
Yang, Z.-Z.2
Hemmings, B.A.3
-
4
-
-
0026768292
-
Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
-
Stewart, C.L.; Kaspar, P.; Brunet, L.J.; Bhatt, H.; Gadi, I.; Köntgen, F.; Abbondanzo, S.J. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992, 359, 76-79.
-
(1992)
Nature
, vol.359
, pp. 76-79
-
-
Stewart, C.L.1
Kaspar, P.2
Brunet, L.J.3
Bhatt, H.4
Gadi, I.5
Köntgen, F.6
Abbondanzo, S.J.7
-
5
-
-
0032211619
-
Paracrine induction of stem cell renewal by LIF-deficient cells
-
Dani, C.; Chambers, I.; Johnstone, S.; Robertson, M.; Ebrahimi, B.; Saito, M.; Taga, T.; Li, M.; Burdon, T.; Nichols, J.; Smith, A. Paracrine induction of stem cell renewal by LIF-deficient cells: A new ES cell regulatory pathway. Dev. Biol. 1998, 203, 149-162.
-
(1998)
A New ES Cell Regulatory Pathway. Dev. Biol
, vol.203
, pp. 149-162
-
-
Dani, C.1
Chambers, I.2
Johnstone, S.3
Robertson, M.4
Ebrahimi, B.5
Saito, M.6
Taga, T.7
Li, M.8
Burdon, T.9
Nichols, J.10
Smith, A.11
-
6
-
-
36749081541
-
P53 regulates maternal reproduction through LIF
-
Hu, W.; Feng, Z.; Teresky, A.K.; Levine, A.J. p53 regulates maternal reproduction through LIF. Nature 2007, 450, 721-724.
-
(2007)
Nature
, vol.450
, pp. 721-724
-
-
Hu, W.1
Feng, Z.2
Teresky, A.K.3
Levine, A.J.4
-
7
-
-
0029061551
-
Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death
-
Ware, C.B.; Horowitz, M.C.; Renshaw, B.R.; Hunt, J.S.; Liggitt, D.; Koblar, S.A.; Gliniak, B.C.; McKenna, H.J.; Papayannopoulou, T.; Thoma, B.; et al. Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Development 1995, 121, 1283-1299.
-
(1995)
Development
, vol.121
, pp. 1283-1299
-
-
Ware, C.B.1
Horowitz, M.C.2
Renshaw, B.R.3
Hunt, J.S.4
Liggitt, D.5
Koblar, S.A.6
Gliniak, B.C.7
McKenna, H.J.8
Papayannopoulou, T.9
Thoma, B.10
-
8
-
-
0029620955
-
Essential function of LIF receptor in motor neurons
-
Li, M.; Sendtner, M.; Smith, A. Essential function of LIF receptor in motor neurons. Nature 1995, 378, 724-727.
-
(1995)
Nature
, vol.378
, pp. 724-727
-
-
Li, M.1
Sendtner, M.2
Smith, A.3
-
9
-
-
9044222888
-
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders
-
Yoshida, K.; Taga, T.; Saito, M.; Suematsu, S.; Kumanogoh, A.; Tanaka, T.; Fujiwara, H.; Hirata, M.; Yamagami, T.; Nakahata, T.; Hirabayashi, T.; Yoneda, Y.; Tanaka, K.; Wang, W.Z.; Mori, C.; Shiota, K.; Yoshida, N.; Kishimoto, T. Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc. Natl. Acad. Sci. USA 1996, 93, 407-411.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 407-411
-
-
Yoshida, K.1
Taga, T.2
Saito, M.3
Suematsu, S.4
Kumanogoh, A.5
Tanaka, T.6
Fujiwara, H.7
Hirata, M.8
Yamagami, T.9
Nakahata, T.10
Hirabayashi, T.11
Yoneda, Y.12
Tanaka, K.13
Wang, W.Z.14
Mori, C.15
Shiota, K.16
Yoshida, N.17
Kishimoto, T.18
-
10
-
-
0034944121
-
Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines
-
Nichols, J.; Chambers, I.; Taga, T.; Smith, A. Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines. Development 2001, 128, 2333-2339.
-
(2001)
Development
, vol.128
, pp. 2333-2339
-
-
Nichols, J.1
Chambers, I.2
Taga, T.3
Smith, A.4
-
11
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans, M.J.; Kaufman, M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292, 154-156.
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
12
-
-
0027233526
-
Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation
-
Escary, J.L.; Perreau, J.; Duménil, D.; Ezine, S.; Brûlet, P. Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation. Nature 1993, 363, 361-364.
-
(1993)
Nature
, vol.363
, pp. 361-364
-
-
Escary, J.L.1
Perreau, J.2
Duménil, D.3
Ezine, S.4
Brûlet, P.5
-
13
-
-
27644483064
-
Regulatory networks in embryo-derived pluripotent stem cells
-
Boiani, M.; Schöler, H.R. Regulatory networks in embryo-derived pluripotent stem cells. Nat. Rev. Mol. Cell Biol. 2005, 6, 872-884.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 872-884
-
-
Boiani, M.1
Schöler, H.R.2
-
14
-
-
0026656933
-
Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor
-
Conquet, F.; Peyriéras, N.; Tiret, L.; Brûlet, P. Inhibited gastrulation in mouse embryos overexpressing the leukemia inhibitory factor. Proc. Natl. Acad. Sci. USA 1992, 89, 8195-8199.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8195-8199
-
-
Conquet, F.1
Peyriéras, N.2
Tiret, L.3
Brûlet, P.4
-
15
-
-
34547570814
-
Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control
-
Mahdavi, A.; Davey, R.E.; Bhola, P.; Yin, T.; Zandstra, P.W. Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control. PLoS Comput. Biol. 2007, 3, e130.
-
(2007)
PLoS Comput. Biol
, vol.3
-
-
Mahdavi, A.1
Davey, R.E.2
Bhola, P.3
Yin, T.4
Zandstra, P.W.5
-
16
-
-
0029061551
-
Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death
-
Ware, C.B.; Horowitz, M.C.; Renshaw, B.R.; Hunt, J.S.; Liggitt, D.; Koblar, S.A.; Gliniak, B.C.; McKenna, H.J.; Papayannopoulou, T.; Thoma, B. Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Development 1995, 121, 1283-1299.
-
(1995)
Development
, vol.121
, pp. 1283-1299
-
-
Ware, C.B.1
Horowitz, M.C.2
Renshaw, B.R.3
Hunt, J.S.4
Liggitt, D.5
Koblar, S.A.6
Gliniak, B.C.7
McKenna, H.J.8
Papayannopoulou, T.9
Thoma, B.10
-
17
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda, K.; Noguchi, K.; Shi, W.; Tanaka, T.; Matsumoto, M.; Yoshida, N.; Kishimoto, T.; Akira, S. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. USA 1997, 94, 3801-3804.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
Kishimoto, T.7
Akira, S.8
-
18
-
-
0033517123
-
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
-
Matsuda, T.; Nakamura, T.; Nakao, K.; Arai, T.; Katsuki, M.; Heike, T.; Yokota, T. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. Embo. J. 1999, 18, 4261-4269.
-
(1999)
Embo. J
, vol.18
, pp. 4261-4269
-
-
Matsuda, T.1
Nakamura, T.2
Nakao, K.3
Arai, T.4
Katsuki, M.5
Heike, T.6
Yokota, T.7
-
19
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying, Q.-L.; Wray, J.; Nichols, J.; Batlle-Morera, L.; Doble, B.; Woodgett, J.; Cohen, P.; Smith, A. The ground state of embryonic stem cell self-renewal. Nature 2008, 453, 519-523.
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.-L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
Cohen, P.7
Smith, A.8
-
20
-
-
58249133797
-
Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation
-
Boyle, K.; Zhang, J.; Nicholson, S.; Trounson, E.; Babon, J.; McManus, E.; Nicola, N.; Robb, L. Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation. Cell Signal. 2008, 21, 394-404.
-
(2008)
Cell Signal
, vol.21
, pp. 394-404
-
-
Boyle, K.1
Zhang, J.2
Nicholson, S.3
Trounson, E.4
Babon, J.5
McManus, E.6
Nicola, N.7
Robb, L.8
-
21
-
-
0033886322
-
Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival
-
Duval, D.; Reinhardt, B.; Kedinger, C.; Boeuf, H. Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival. Faseb J. 2000, 14, 1577-1584.
-
(2000)
Faseb J
, vol.14
, pp. 1577-1584
-
-
Duval, D.1
Reinhardt, B.2
Kedinger, C.3
Boeuf, H.4
-
22
-
-
11244281579
-
Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
-
Li, Y.; McClintick, J.; Zhong, L.; Edenberg, H.J.; Yoder, M.C.; Chan, R.J. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 2005, 105, 635-637.
-
(2005)
Blood
, vol.105
, pp. 635-637
-
-
Li, Y.1
McClintick, J.2
Zhong, L.3
Edenberg, H.J.4
Yoder, M.C.5
Chan, R.J.6
-
23
-
-
33744990866
-
Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells
-
Forrai, A.; Boyle, K.; Hart, A.H.; Hartley, L.; Rakar, S.; Willson, T.A.; Simpson, K.M.; Roberts, A.W.; Alexander, W.S.; Voss, A.K.; Robb, L. Absence of suppressor of cytokine signalling 3 reduces self-renewal and promotes differentiation in murine embryonic stem cells. Stem Cells 2006, 24, 604-614.
-
(2006)
Stem Cells
, vol.24
, pp. 604-614
-
-
Forrai, A.1
Boyle, K.2
Hart, A.H.3
Hartley, L.4
Rakar, S.5
Willson, T.A.6
Simpson, K.M.7
Roberts, A.W.8
Alexander, W.S.9
Voss, A.K.10
Robb, L.11
-
24
-
-
0037415694
-
SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation
-
Takahashi, Y.; Carpino, N.; Cross, J.C.; Torres, M.; Parganas, E.; Ihle, J.N. SOCS3: An essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J. 2003, 22, 372-384.
-
(2003)
EMBO J
, vol.22
, pp. 372-384
-
-
Takahashi, Y.1
Carpino, N.2
Cross, J.C.3
Torres, M.4
Parganas, E.5
Ihle, J.N.6
-
25
-
-
46349097234
-
Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway
-
Takahashi, Y.; Takahashi, M.; Carpino, N.; Jou, S.-T.; Chao, J.-R.; Tanaka, S.; Shigeyoshi, Y.; Parganas, E.; Ihle, J.N. Leukemia inhibitory factor regulates trophoblast giant cell differentiation via Janus kinase 1-signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway. Mol. Endocrinol. 2008, 22, 1673-1681.
-
(2008)
Mol. Endocrinol
, vol.22
, pp. 1673-1681
-
-
Takahashi, Y.1
Takahashi, M.2
Carpino, N.3
Jou, S.-T.4
Chao, J.-R.5
Tanaka, S.6
Shigeyoshi, Y.7
Parganas, E.8
Ihle, J.N.9
-
26
-
-
33751252282
-
Jak2 and Tyk2 are necessary for lineage-specific differentiation, but not for the maintenance of self-renewal of mouse embryonic stem cells
-
Chung, B.M.; Kang, H.C.; Han, S.Y.; Heo, H.S.; Lee, J.J.; Jeon, J.; Lim, J.Y.; Shin, I.; Hong, S.H.; Cho, Y.S.; Kim, C.G. Jak2 and Tyk2 are necessary for lineage-specific differentiation, but not for the maintenance of self-renewal of mouse embryonic stem cells. Biochem. Biophys. Res. Commun. 2006, 351, 682-688.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.351
, pp. 682-688
-
-
Chung, B.M.1
Kang, H.C.2
Han, S.Y.3
Heo, H.S.4
Lee, J.J.5
Jeon, J.6
Lim, J.Y.7
Shin, I.8
Hong, S.H.9
Cho, Y.S.10
Kim, C.G.11
-
27
-
-
0029923977
-
Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways
-
Ernst, M.; Oates, A.; Dunn, A.R. Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways. J. Biol. Chem. 1996, 271, 30136-30143.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 30136-30143
-
-
Ernst, M.1
Oates, A.2
Dunn, A.R.3
-
28
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S.J.; Meraz, M.A.; White, J.M.; Lampe, P.A.; Riley, J.K.; Arthur, C.D.; King, K.L.; Sheehan, K.C.; Yin, L.; Pennica, D.; Johnson, E.M.; Schreiber, R.D. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 1998, 93, 373-383.
-
(1998)
Cell
, vol.93
, pp. 373-383
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
King, K.L.7
Sheehan, K.C.8
Yin, L.9
Pennica, D.10
Johnson, E.M.11
Schreiber, R.D.12
-
29
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer, H.; Cumano, A.; Müller, M.; Wu, H.; Huffstadt, U.; Pfeffer, K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 1998, 93, 397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Müller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
30
-
-
33644547703
-
An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival
-
Yang, W.; Klaman, L.D.; Chen, B.; Araki, T.; Harada, H.; Thomas, S.M.; George, E.L.; Neel, B.G. An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival. Dev. Cell. 2006, 10, 317-327.
-
(2006)
Dev. Cell
, vol.10
, pp. 317-327
-
-
Yang, W.1
Klaman, L.D.2
Chen, B.3
Araki, T.4
Harada, H.5
Thomas, S.M.6
George, E.L.7
Neel, B.G.8
-
31
-
-
0141567655
-
A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis
-
Chan, R.J.; Johnson, S.A.; Li, Y.; Yoder, M.C.; Feng, G.-S. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood 2003, 102, 2074-2080.
-
(2003)
Blood
, vol.102
, pp. 2074-2080
-
-
Chan, R.J.1
Johnson, S.A.2
Li, Y.3
Yoder, M.C.4
Feng, G.-S.5
-
32
-
-
62849093631
-
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase
-
Wu, D.; Pang, Y.; Ke, Y.; Yu, J.; He, Z.; Tautz, L.; Mustelin, T.; Ding, S.; Huang, Z.; Feng, G.-S. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. PLoS ONE 2009, 4, e4914.
-
(2009)
PLoS ONE
, vol.4
-
-
Wu, D.1
Pang, Y.2
Ke, Y.3
Yu, J.4
He, Z.5
Tautz, L.6
Mustelin, T.7
Ding, S.8
Huang, Z.9
Feng, G.-S.10
-
33
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin, G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 1981, 78, 7634-7638.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
34
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K.; Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
35
-
-
0010472032
-
Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1)
-
Solter, D.; Knowles, B.B. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc. Natl. Acad. Sci. USA 1978, 75, 5565-5569.
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 5565-5569
-
-
Solter, D.1
Knowles, B.B.2
-
36
-
-
0025886340
-
Octamania The POU factors in murine development
-
Schöler, H.R. Octamania: The POU factors in murine development. Trends Genet. 1991, 7, 323-329.
-
(1991)
Trends Genet
, vol.7
, pp. 323-329
-
-
Schöler, H.R.1
-
37
-
-
0024462072
-
Octamer binding proteins confer transcriptional activity in early mouse embryogenesis
-
Scholer, H.R.; Balling, R.; Hatzopoulos, A.K.; Suzuki, N.; Gruss, P. Octamer binding proteins confer transcriptional activity in early mouse embryogenesis. EMBO J. 1989, 8, 2551-2557.
-
(1989)
EMBO J
, vol.8
, pp. 2551-2557
-
-
Scholer, H.R.1
Balling, R.2
Hatzopoulos, A.K.3
Suzuki, N.4
Gruss, P.5
-
38
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui, K.; Tokuzawa, Y.; Itoh, H.; Segawa, K.; Murakami, M.; Takahashi, K.; Maruyama, M.; Maeda, M.; Yamanaka, S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113, 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
39
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers, I.; Colby, D.; Robertson, M.; Nichols, J.; Lee, S.; Tweedie, S.; Smith, A. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003, 113, 643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
Tweedie, S.6
Smith, A.7
-
40
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J.A.; Itskovitz-Eldor, J.; Shapiro, S.S.; Waknitz, M.A.; Swiergiel, J.J.; Marshall, V.S.; Jones, J.M. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282, 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
41
-
-
0344845415
-
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
-
Ying, Q.L.; Nichols, J.; Chambers, I.; Smith, A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003, 115, 281-292.
-
(2003)
Cell
, vol.115
, pp. 281-292
-
-
Ying, Q.L.1
Nichols, J.2
Chambers, I.3
Smith, A.4
-
42
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato, N.; Meijer, L.; Skaltsounis, L.; Greengard, P.; Brivanlou, A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 2004, 10, 55-63.
-
(2004)
Nat. Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
43
-
-
0035200856
-
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation
-
Tang, H.; Hornstein, E.; Stolovich, M.; Levy, G.; Livingstone, M.; Templeton, D.; Avruch, J.; Meyuhas, O. Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Mol. Cell Biol. 2001, 21, 8671-8683.
-
(2001)
Mol. Cell Biol
, vol.21
, pp. 8671-8683
-
-
Tang, H.1
Hornstein, E.2
Stolovich, M.3
Levy, G.4
Livingstone, M.5
Templeton, D.6
Avruch, J.7
Meyuhas, O.8
-
44
-
-
0033761629
-
Synthesis of the translational apparatus is regulated at the translational level
-
Meyuhas, O. Synthesis of the translational apparatus is regulated at the translational level. Eur. J. Biochem. 2000, 267, 6321-6330.
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 6321-6330
-
-
Meyuhas, O.1
-
45
-
-
0024245022
-
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
-
Smith, A.G.; Heath, J.K.; Donaldson, D.D.; Wong, G.G.; Moreau, J.; Stahl, M.; Rogers, D. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 1988, 336, 688-690.
-
(1988)
Nature
, vol.336
, pp. 688-690
-
-
Smith, A.G.1
Heath, J.K.2
Donaldson, D.D.3
Wong, G.G.4
Moreau, J.5
Stahl, M.6
Rogers, D.7
-
46
-
-
2442690993
-
Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF)
-
Gearing, D.P.; Gough, N.M.; King, J.A.; Hilton, D.J.; Nicola, N.A.; Simpson, R.J.; Nice, E.C.; Kelso, A.; Metcalf, D. Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J. 1987, 6, 3995-4002.
-
(1987)
EMBO J
, vol.6
, pp. 3995-4002
-
-
Gearing, D.P.1
Gough, N.M.2
King, J.A.3
Hilton, D.J.4
Nicola, N.A.5
Simpson, R.J.6
Nice, E.C.7
Kelso, A.8
Metcalf, D.9
-
47
-
-
0024205842
-
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
-
Williams, R.L.; Hilton, D.J.; Pease, S.; Willson, T.A.; Stewart, C.L.; Gearing, D.P.; Wagner, E.F.; Metcalf, D.; Nicola, N.A.; Gough, N.M. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988, 336, 684-687.
-
(1988)
Nature
, vol.336
, pp. 684-687
-
-
Williams, R.L.1
Hilton, D.J.2
Pease, S.3
Willson, T.A.4
Stewart, C.L.5
Gearing, D.P.6
Wagner, E.F.7
Metcalf, D.8
Nicola, N.A.9
Gough, N.M.10
-
48
-
-
0346220073
-
Defined conditions for neural commitment and differentiation
-
Ying, Q.-L.; Smith, A.G. Defined conditions for neural commitment and differentiation. Meth. Enzymol. 2003, 365, 327-341.
-
(2003)
Meth. Enzymol
, vol.365
, pp. 327-341
-
-
Ying, Q.-L.1
Smith, A.G.2
-
49
-
-
34247154612
-
Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
-
Storm, M.P.; Bone, H.K.; Beck, C.G.; Bourillot, P.-Y.; Schreiber, V.; Damiano, T.; Nelson, A.; Savatier, P.; Welham, M.J. Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J. Biol. Chem. 2007, 282, 6265-6273.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 6265-6273
-
-
Storm, M.P.1
Bone, H.K.2
Beck, C.G.3
Bourillot, P.-Y.4
Schreiber, V.5
Damiano, T.6
Nelson, A.7
Savatier, P.8
Welham, M.J.9
-
50
-
-
33646549601
-
Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells
-
Watanabe, S.; Umehara, H.; Murayama, K.; Okabe, M.; Kimura, T.; Nakano, T. Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. Oncogene 2006, 25, 2697-2707.
-
(2006)
Oncogene
, vol.25
, pp. 2697-2707
-
-
Watanabe, S.1
Umehara, H.2
Murayama, K.3
Okabe, M.4
Kimura, T.5
Nakano, T.6
-
51
-
-
9144239955
-
Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
-
Paling, N.R.D.; Wheadon, H.; Bone, H.K.; Welham, M.J. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J. Biol. Chem. 2004, 279, 48063-48070.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 48063-48070
-
-
Paling, N.R.D.1
Wheadon, H.2
Bone, H.K.3
Welham, M.J.4
-
52
-
-
34548587064
-
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
-
Kunath, T.; Saba-El-Leil, M.K.; Almousailleakh, M.; Wray, J.; Meloche, S.; Smith, A. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 2007, 134, 2895-2902.
-
(2007)
Development
, vol.134
, pp. 2895-2902
-
-
Kunath, T.1
Saba-El-Leil, M.K.2
Almousailleakh, M.3
Wray, J.4
Meloche, S.5
Smith, A.6
-
53
-
-
0035824552
-
The ribosomal S6 kinases, cAMP-responsive element-binding, and STAT3 proteins are regulated by different leukemia inhibitory factor signaling pathways in mouse embryonic stem cells
-
Boeuf, H.; Merienne, K.; Jacquot, S.; Duval, D.; Zeniou, M.; Hauss, C.; Reinhardt, B.; Huss-Garcia, Y.; Dierich, A.; Frank, D.A.; Hanauer, A.; Kedinger, C. The ribosomal S6 kinases, cAMP-responsive element-binding, and STAT3 proteins are regulated by different leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. J. Biol. Chem. 2001, 276, 46204-46211.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 46204-46211
-
-
Boeuf, H.1
Merienne, K.2
Jacquot, S.3
Duval, D.4
Zeniou, M.5
Hauss, C.6
Reinhardt, B.7
Huss-Garcia, Y.8
Dierich, A.9
Frank, D.A.10
Hanauer, A.11
Kedinger, C.12
-
54
-
-
0032127977
-
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
-
Niwa, H.; Burdon, T.; Chambers, I.; Smith, A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 1998, 12, 2048-2060.
-
(1998)
Genes Dev
, vol.12
, pp. 2048-2060
-
-
Niwa, H.1
Burdon, T.2
Chambers, I.3
Smith, A.4
-
55
-
-
0028011911
-
Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways
-
Yoshida, K.; Chambers, I.; Nichols, J.; Smith, A.; Saito, M.; Yasukawa, K.; Shoyab, M.; Taga, T.; Kishimoto, T. Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways. Mech. Dev. 1994, 45, 163-171.
-
(1994)
Mech. Dev
, vol.45
, pp. 163-171
-
-
Yoshida, K.1
Chambers, I.2
Nichols, J.3
Smith, A.4
Saito, M.5
Yasukawa, K.6
Shoyab, M.7
Taga, T.8
Kishimoto, T.9
-
56
-
-
0028153042
-
Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor
-
Nichols, J.; Chambers, I.; Smith, A. Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor. Exp. Cell Res. 1994, 215, 237-239.
-
(1994)
Exp. Cell Res
, vol.215
, pp. 237-239
-
-
Nichols, J.1
Chambers, I.2
Smith, A.3
-
57
-
-
0033049657
-
Essential role of STAT3 for embryonic stem cell pluripotency
-
Raz, R.; Lee, C.K.; Cannizzaro, L.A.; d'Eustachio, P.; Levy, D.E. Essential role of STAT3 for embryonic stem cell pluripotency. Proc. Natl. Acad.Sci. USA 1999, 96, 2846-2851.
-
(1999)
Proc. Natl. Acad.Sci. USA
, vol.96
, pp. 2846-2851
-
-
Raz, R.1
Lee, C.K.2
Cannizzaro, L.A.3
D'eustachio, P.4
Levy, D.E.5
-
58
-
-
44849100139
-
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3
-
Cinelli, P.; Casanova, E.A.; Uhlig, S.; Lochmatter, P.; Matsuda, T.; Yokota, T.; Rülicke, T.; Ledermann, B.; Bürki, K. Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev. Biol. 2008, 8, 57.
-
(2008)
BMC Dev. Biol
, vol.8
, pp. 57
-
-
Cinelli, P.1
Casanova, E.A.2
Uhlig, S.3
Lochmatter, P.4
Matsuda, T.5
Yokota, T.6
Rülicke, T.7
Ledermann, B.8
Bürki, K.9
-
59
-
-
62549133135
-
Imaging of STAT3 Signaling Pathway During Mouse Embryonic Stem Cell Differentiation
-
Xie, X.; Chan, K.; Cao, F.; Huang, M.; Li, Z.; Lee, A.; Weissman, I.; Wu, J. Imaging of STAT3 Signaling Pathway During Mouse Embryonic Stem Cell Differentiation. Stem Cells Dev. 2008, 18, 205-214.
-
(2008)
Stem Cells Dev
, vol.18
, pp. 205-214
-
-
Xie, X.1
Chan, K.2
Cao, F.3
Huang, M.4
Li, Z.5
Lee, A.6
Weissman, I.7
Wu, J.8
-
60
-
-
65449118073
-
Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives
-
Trouillas, M.; Saucourt, C.; Guillotin, B.; Gauthereau, X.; Ding, L.; Buchholz, F.; Doss, M.X.; Sachinidis, A.; Hescheler, J.; Hummel, O.; Huebner, N.; Kolde, R.; Vilo, J.; Schultz, H.; Boeuf, H. Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives. BMC Genomics 2009, 10, 73.
-
(2009)
BMC Genomics
, vol.10
, pp. 73
-
-
Trouillas, M.1
Saucourt, C.2
Guillotin, B.3
Gauthereau, X.4
Ding, L.5
Buchholz, F.6
Doss, M.X.7
Sachinidis, A.8
Hescheler, J.9
Hummel, O.10
Huebner, N.11
Kolde, R.12
Vilo, J.13
Schultz, H.14
Boeuf, H.15
-
61
-
-
28444480969
-
Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells
-
Sekkaï, D.; Gruel, G.; Herry, M.; Moucadel, V.; Constantinescu, S.N.; Albagli, O.; Tronik-Le Roux, D.; Vainchenker, W.; Bennaceur-Griscelli, A. Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells. Stem Cells 2005, 23, 1634-1642.
-
(2005)
Stem Cells
, vol.23
, pp. 1634-1642
-
-
Sekkaï, D.1
Gruel, G.2
Herry, M.3
Moucadel, V.4
Constantinescu, S.N.5
Albagli, O.6
Tronik-Le roux, D.7
Vainchenker, W.8
Bennaceur-Griscelli, A.9
-
62
-
-
16844364151
-
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
-
Cartwright, P.; McLean, C.; Sheppard, A.; Rivett, D.; Jones, K.; Dalton, S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 2005, 132, 885-896.
-
(2005)
Development
, vol.132
, pp. 885-896
-
-
Cartwright, P.1
McLean, C.2
Sheppard, A.3
Rivett, D.4
Jones, K.5
Dalton, S.6
-
63
-
-
69249107379
-
Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog
-
1002/stem.110
-
Bourillot, P.; Aksoy, I.; Schreiber, V.; Wianny, F.; Schulz, H.; Hummel, O.; Hubner, N.; Savatier, P. Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog. Stem Cells 2009, 10.1002/stem.110.
-
(2009)
Stem Cells
, vol.10
-
-
Bourillot, P.1
Aksoy, I.2
Schreiber, V.3
Wianny, F.4
Schulz, H.5
Hummel, O.6
Hubner, N.7
Savatier, P.8
-
64
-
-
70450270857
-
Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal
-
Hall, J.; Guo, G.; Wray, J.; Eyres, I.; Nichols, J.; Grotewold, L.; Morfopoulou, S.; Humphreys, P.; Mansfield, W.; Walker, R.; Tomlinson, S.; Smith, A. Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal. Cell Stem Cell 2009, 5, 597-609.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 597-609
-
-
Hall, J.1
Guo, G.2
Wray, J.3
Eyres, I.4
Nichols, J.5
Grotewold, L.6
Morfopoulou, S.7
Humphreys, P.8
Mansfield, W.9
Walker, R.10
Tomlinson, S.11
Smith, A.12
-
65
-
-
0033564117
-
Forced expression of the homeobox-containing gene Pem blocks differentiation of embryonic stem cells
-
Fan, Y.; Melhem, M.F.; Chaillet, J.R. Forced expression of the homeobox-containing gene Pem blocks differentiation of embryonic stem cells. Dev. Biol. 1999, 210, 481-496.
-
(1999)
Dev. Biol
, vol.210
, pp. 481-496
-
-
Fan, Y.1
Melhem, M.F.2
Chaillet, J.R.3
-
66
-
-
79953010127
-
Pramel7 Mediates LIF/STAT3 Dependent Self-Renewal in Embryonic Stem Cells
-
1002/stem.588
-
Casanova, E.A.; Shakhova, O.; Patel, S.S.; Asner, I.N.; Pelczar, P.; Weber, F.A.; Graf, U.; Sommer, L.; Bürki, K.; Cinelli, P. Pramel7 Mediates LIF/STAT3 Dependent Self-Renewal in Embryonic Stem Cells. Stem Cells 2010, 10.1002/stem.588.
-
(2010)
Stem Cells
, vol.10
-
-
Casanova, E.A.1
Shakhova, O.2
Patel, S.S.3
Asner, I.N.4
Pelczar, P.5
Weber, F.A.6
Graf, U.7
Sommer, L.8
Bürki, K.9
Cinelli, P.10
-
67
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen, X.; Xu, H.; Yuan, P.; Fang, F.; Huss, M.; Vega, V.B.; Wong, E.; Orlov, Y.L.; Zhang, W.; Jiang, J.; Loh, Y.-H.; Yeo, H.C.; Yeo, Z.X.; Narang, V.; Govindarajan, K.R.; Leong, B.; Shahab, A.; Ruan, Y.; Bourque, G.; Sung, W.-K.; Clarke, N.D.; Wei, C.-L.; Ng, H.-H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008, 133, 1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
Loh, Y.-H.11
Yeo, H.C.12
Yeo, Z.X.13
Narang, V.14
Govindarajan, K.R.15
Leong, B.16
Shahab, A.17
Ruan, Y.18
Bourque, G.19
Sung, W.-K.20
Clarke, N.D.21
Wei, C.-L.22
Ng, H.-H.23
more..
-
68
-
-
37349062460
-
Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases pim-1 and pim-3
-
Aksoy, I.; Sakabedoyan, C.; Bourillot, P.-Y.; Malashicheva, A.B.; Mancip, J.; Knoblauch, K.; Afanassieff, M.; Savatier, P. Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases pim-1 and pim-3. Stem Cells 2007, 25, 2996-3004.
-
(2007)
Stem Cells
, vol.25
, pp. 2996-3004
-
-
Aksoy, I.1
Sakabedoyan, C.2
Bourillot, P.-Y.3
Malashicheva, A.B.4
Mancip, J.5
Knoblauch, K.6
Afanassieff, M.7
Savatier, P.8
-
69
-
-
67650032868
-
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
-
Niwa, H.; Ogawa, K.; Shimosato, D.; Adachi, K. A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 2009, 460, 118-122.
-
(2009)
Nature
, vol.460
, pp. 118-122
-
-
Niwa, H.1
Ogawa, K.2
Shimosato, D.3
Adachi, K.4
-
70
-
-
70349934958
-
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
-
Nichols, J.; Silva, J.; Roode, M.; Smith, A. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 2009, 136, 3215-3222.
-
(2009)
Development
, vol.136
, pp. 3215-3222
-
-
Nichols, J.1
Silva, J.2
Roode, M.3
Smith, A.4
-
71
-
-
0033152966
-
Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
-
Burdon, T.; Stracey, C.; Chambers, I.; Nichols, J.; Smith, A. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev. Biol. 1999, 210, 30-43.
-
(1999)
Dev. Biol
, vol.210
, pp. 30-43
-
-
Burdon, T.1
Stracey, C.2
Chambers, I.3
Nichols, J.4
Smith, A.5
-
72
-
-
0031936668
-
Ras versus cyclin-dependent kinase inhibitors
-
Lloyd, A.C. Ras versus cyclin-dependent kinase inhibitors. Curr. Opin. Genet. Dev. 1998, 8, 43-48.
-
(1998)
Curr. Opin. Genet. Dev
, vol.8
, pp. 43-48
-
-
Lloyd, A.C.1
-
73
-
-
4143145146
-
Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos
-
Wang, Y.; Wang, F.; Sun, T.; Trostinskaia, A.; Wygle, D.; Puscheck, E.; Rappolee, D.A. Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos. Dev. Dyn. 2004, 231, 72-87.
-
(2004)
Dev. Dyn
, vol.231
, pp. 72-87
-
-
Wang, Y.1
Wang, F.2
Sun, T.3
Trostinskaia, A.4
Wygle, D.5
Puscheck, E.6
Rappolee, D.A.7
-
74
-
-
34548183330
-
Requirement for ERK MAP kinase in mouse preimplantation development
-
Maekawa, M.; Yamamoto, T.; Kohno, M.; Takeichi, M.; Nishida, E. Requirement for ERK MAP kinase in mouse preimplantation development. Development 2007, 134, 2751-2759.
-
(2007)
Development
, vol.134
, pp. 2751-2759
-
-
Maekawa, M.1
Yamamoto, T.2
Kohno, M.3
Takeichi, M.4
Nishida, E.5
-
75
-
-
0031900740
-
Signal transduction through MAP kinase cascades
-
Lewis, T.S.; Shapiro, P.S.; Ahn, N.G. Signal transduction through MAP kinase cascades. Adv. Cancer Res. 1998, 74, 49-139.
-
(1998)
Adv. Cancer Res
, vol.74
, pp. 49-139
-
-
Lewis, T.S.1
Shapiro, P.S.2
Ahn, N.G.3
-
76
-
-
0038100185
-
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
-
Takahashi, K.; Mitsui, K.; Yamanaka, S. Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature 2003, 423, 541-545.
-
(2003)
Nature
, vol.423
, pp. 541-545
-
-
Takahashi, K.1
Mitsui, K.2
Yamanaka, S.3
-
77
-
-
0037103988
-
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells
-
Jirmanova, L.; Afanassieff, M.; Gobert-Gosse, S.; Markossian, S.; Savatier, P. Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene 2002, 21, 5515-5528.
-
(2002)
Oncogene
, vol.21
, pp. 5515-5528
-
-
Jirmanova, L.1
Afanassieff, M.2
Gobert-Gosse, S.3
Markossian, S.4
Savatier, P.5
-
78
-
-
0037799274
-
Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha
-
Hallmann, D.; Trümper, K.; Trusheim, H.; Ueki, K.; Kahn, C.R.; Cantley, L.C.; Fruman, D.A.; Hörsch, D. Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha. J. Biol. Chem. 2003, 278, 5099-5108.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 5099-5108
-
-
Hallmann, D.1
Trümper, K.2
Trusheim, H.3
Ueki, K.4
Kahn, C.R.5
Cantley, L.C.6
Fruman, D.A.7
Hörsch, D.8
-
79
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies
-
Moon, R.T.; Kohn, A.D.; De Ferrari, G.V.; Kaykas, A. WNT and beta-catenin signalling: Diseases and therapies. Nat. Rev. Genet. 2004, 5, 691-701.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
de Ferrari, G.V.3
Kaykas, A.4
-
80
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson, W.J.; Nusse, R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004, 303, 1483-1487.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
81
-
-
0036709213
-
Signalling, cell cycle and pluripotency in embryonic stem cells
-
Burdon, T.; Smith, A.; Savatier, P. Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell. Biol. 2002, 12, 432-438.
-
(2002)
Trends Cell. Biol
, vol.12
, pp. 432-438
-
-
Burdon, T.1
Smith, A.2
Savatier, P.3
-
82
-
-
78651099000
-
Phosphorylation of Sox2 cooperates in reprogramming to pluripotent stem cells
-
Jeong, C.-H.; Cho, Y.-Y.; Kim, M.-O.; Kim, S.-H.; Cho, E.-J.; Lee, S.-Y.; Jeon, Y.-J.; Lee, K.Y.; Yao, K.; Keum, Y.-S.; Bode, A.M.; Dong, Z. Phosphorylation of Sox2 cooperates in reprogramming to pluripotent stem cells. Stem Cells 2010, 28, 2141-2150.
-
(2010)
Stem Cells
, vol.28
, pp. 2141-2150
-
-
Jeong, C.-H.1
Cho, Y.-Y.2
Kim, M.-O.3
Kim, S.-H.4
Cho, E.-J.5
Lee, S.-Y.6
Jeon, Y.-J.7
Lee, K.Y.8
Yao, K.9
Keum, Y.-S.10
Bode, A.M.11
Dong, Z.12
-
83
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut, I.; Schnieke, A.E.; McWhir, J.; Kind, A.J.; Campbell, K.H. Viable offspring derived from fetal and adult mammalian cells. Nature 1997, 385, 810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
84
-
-
34249890186
-
Developmental reprogramming after chromosome transfer into mitotic mouse zygotes
-
Egli, D.; Rosains, J.; Birkhoff, G.; Eggan, K. Developmental reprogramming after chromosome transfer into mitotic mouse zygotes. Nature 2007, 447, 679-685.
-
(2007)
Nature
, vol.447
, pp. 679-685
-
-
Egli, D.1
Rosains, J.2
Birkhoff, G.3
Eggan, K.4
-
85
-
-
0032560827
-
Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
-
Wakayama, T.; Perry, A.C.; Zuccotti, M.; Johnson, K.R.; Yanagimachi, R. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998, 394, 369-374.
-
(1998)
Nature
, vol.394
, pp. 369-374
-
-
Wakayama, T.1
Perry, A.C.2
Zuccotti, M.3
Johnson, K.R.4
Yanagimachi, R.5
-
86
-
-
39149086020
-
Induction of pluripotent stem cells from fibroblast cultures
-
Takahashi, K.; Okita, K.; Nakagawa, M.; Yamanaka, S. Induction of pluripotent stem cells from fibroblast cultures. Nat. Protoc. 2007, 2, 3081-3089.
-
(2007)
Nat. Protoc
, vol.2
, pp. 3081-3089
-
-
Takahashi, K.1
Okita, K.2
Nakagawa, M.3
Yamanaka, S.4
-
87
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K.; Tanabe, K.; Ohnuki, M.; Narita, M.; Ichisaka, T.; Tomoda, K.; Yamanaka, S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131, 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
88
-
-
75349088911
-
The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells
-
Heng, J.-C.D.; Feng, B.; Han, J.; Jiang, J.; Kraus, P.; Ng, J.-H.; Orlov, Y.L.; Huss, M.; Yang, L.; Lufkin, T.; Lim, B.; Ng, H.-H. The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells. Cell Stem Cell 2010, 6, 167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.-C.D.1
Feng, B.2
Han, J.3
Jiang, J.4
Kraus, P.5
Ng, J.-H.6
Orlov, Y.L.7
Huss, M.8
Yang, L.9
Lufkin, T.10
Lim, B.11
Ng, H.-H.12
-
89
-
-
55849117368
-
Generation of Mouse Induced Pluripotent Stem Cells without Viral Vectors
-
Okita, K.; Nakagawa, M.; Hyenjong, H.; Ichisaka, T.; Yamanaka, S. Generation of Mouse Induced Pluripotent Stem Cells without Viral Vectors. Science 2008, 322, 949-953.
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
90
-
-
77956199358
-
Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
-
Yang, J.; van Oosten, A.L.; Theunissen, T.W.; Guo, G.; Silva, J.C.R.; Smith, A. Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency. Cell Stem Cell 2010, 7, 319-328.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 319-328
-
-
Yang, J.1
van Oosten, A.L.2
Theunissen, T.W.3
Guo, G.4
Silva, J.C.R.5
Smith, A.6
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