A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by Shp2 tyrosine phosphatase

PLoS ONE

Volumn 4, Issue 3, 2009, Pages

  Wu, Dongmei ^a   Pang, Yuhong ^a   Ke, Yuehai ^a   Yu, Jianxiu ^a   He, Zhao ^a   Tautz, Lutz ^a   Mustelin, Tomas ^a   Ding, Sheng ^b   Huang, Ziwei ^a   Feng, Gen Sheng ^a  

^a BURNHAM INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; SMAD PROTEIN; SMALL INTERFERING RNA; STAT3 PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; GENE DELETION; GENE EXPRESSION; GENETIC CONSERVATION; GERM LAYER; GROWTH REGULATION; HOMOZYGOSITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; ENZYMOLOGY; GENE SILENCING; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; GENE DELETION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; PLURIPOTENT STEM CELLS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 62849093631     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004914     Document Type: Article

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