-
1
-
-
0023374314
-
Reaction of monoclonal antibodies with plasma membrane proteins after binding on nitrocellulose: Renaturation of antigenic sites and reduction of non-specific antibody binding
-
doi:10.1016/ 0003-2697(87)90360-5
-
Birk HW & Koepsell H 1987 Reaction of monoclonal antibodies with plasma membrane proteins after binding on nitrocellulose: renaturation of antigenic sites and reduction of non-specific antibody binding. Analytical Biochemistry 164 12-22. (doi:10.1016/ 0003-2697(87)90360-5)
-
(1987)
Analytical Biochemistry
, vol.164
, pp. 12-22
-
-
Birk, H.W.1
Koepsell, H.2
-
2
-
-
0032736416
-
Measurement of thyroid-stimulating hormone receptor autoantibodies by ELISA
-
Bolton J, Sanders J, Oda Y, Chapman C, Konno R, Furmaniak J & Rees Smith B 1999 Measurement of thyroid-stimulating hormone receptor autoantibodies by ELISA. Clinical Chemistry 45 2285-2287.
-
(1999)
Clinical Chemistry
, vol.45
, pp. 2285-2287
-
-
Bolton, J.1
Sanders, J.2
Oda, Y.3
Chapman, C.4
Konno, R.5
Furmaniak, J.6
Smith, B.R.7
-
3
-
-
0027404023
-
Convergent evolution of similar enzymatic function on different protein folds: The hexokinase, ribokinase and galactokinase families of sugar kinases
-
(doi:10.1002/pro.5560020104)
-
Bork P, Sander C & Valencia A 1993 Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase and galactokinase families of sugar kinases. Protein Science 2 31-40. (doi:10.1002/pro.5560020104)
-
(1993)
Protein Science
, vol.2
, pp. 31-40
-
-
Bork, P.1
Sander, C.2
Valencia, A.3
-
4
-
-
1942472979
-
Thyroid stimulation does not require antibodies with identical epitopes but does involve recognition of acritical conformation attheNterminus of the thyrotropin receptor A-subunit
-
(doi:10.1210/jc.2003-031554)
-
Chazenbalk GD, Latrofa F, McLachlan SM & Rapoport B 2004 Thyroid stimulation does not require antibodies with identical epitopes but does involve recognition of acritical conformation attheNterminus of the thyrotropin receptor A-subunit. JournalofClinical Endocrinology and Metabolism 89 1788-1793. (doi:10.1210/jc.2003-031554)
-
(2004)
JournalofClinical Endocrinology and Metabolism
, vol.89
, pp. 1788-1793
-
-
Chazenbalk, G.D.1
Latrofa, F.2
McLachlan, S.M.3
Rapoport, B.4
-
5
-
-
0035805619
-
A full biological response to autoantibodies in Graves' disease requires a disulfide-bond loop in the thyrotropin N-terminus homologous to a laminin EGF-like domain
-
(doi:10.1074/jbc.M008001200)
-
Chen CR, Tanaka K, Chazenbalk GD, McLachlan SM & Rapoport B 2001 A full biological response to autoantibodies in Graves' disease requires a disulfide-bond loop in the thyrotropin N-terminus homologous to a laminin EGF-like domain. Journal of Biological Chemistry 276 14767-14772. (doi:10.1074/jbc.M008001200)
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 14767-14772
-
-
Chen, C.R.1
Tanaka, K.2
Chazenbalk, G.D.3
McLachlan, S.M.4
Rapoport, B.5
-
6
-
-
77950194483
-
Thyrotropin (TSH) receptor residue E251 in the extracellular leucine-rich repeat domain is critical for linking TSH binding to receptor activation
-
(doi:10.1210/en.2009-1430)
-
Chen CR, McLachlan SM & Rapoport B 2010 Thyrotropin (TSH) receptor residue E251 in the extracellular leucine-rich repeat domain is critical for linking TSH binding to receptor activation. Endocrinology 151 1940-1947. (doi:10.1210/en.2009-1430)
-
(2010)
Endocrinology
, vol.151
, pp. 1940-1947
-
-
Chen, C.R.1
McLachlan, S.M.2
Rapoport, B.3
-
7
-
-
0028103275
-
The CCP4 Suite: Programmes for protein Crystallography
-
Collaborative Computational project, number 4
-
Collaborative Computational project, number 4 1994 The CCP4 Suite: Programmes for protein Crystallography. Acta Crystallographica D50 760-763.
-
(1994)
Acta Crystallographica
, vol.D50
, pp. 760-763
-
-
-
8
-
-
9644295678
-
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity
-
(doi:10.1210/me.2004-0231)
-
Costagliola S, Bonomi M, Morganthaler NG, Van Durme J, Panneels V, Refetoff S & Vassart G 2004 Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Molecular Endocrinology 18 3020-3034. (doi:10.1210/me.2004-0231)
-
(2004)
Molecular Endocrinology
, vol.18
, pp. 3020-3034
-
-
Costagliola, S.1
Bonomi, M.2
Morganthaler, N.G.3
Durme, J.V.4
Panneels, V.5
Refetoff, S.6
Vassart, G.7
-
9
-
-
33749641136
-
The Pymol molecular graphics system
-
San Carlos, CA
-
DeLano WL 2002 The Pymol molecular graphics system. DeLano Scientific, San Carlos, CA. http://pymol.sourceforge.net/.
-
(2002)
DeLano Scientific
-
-
Delano, W.L.1
-
11
-
-
77955739738
-
Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample
-
(doi:10.1111/j.1365-2265.2010.03831.x)
-
Evans M, Sanders J, Tagami T, Sanders P, Young S, Roberts E, Wilmot J, Hu X, Kabelis K, Clark J et al. 2010 Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample. Clinical Endocrinology 73 404-412. (doi:10.1111/j.1365-2265.2010.03831.x)
-
(2010)
Clinical Endocrinology
, vol.73
, pp. 404-412
-
-
Evans, M.1
Sanders, J.2
Tagami, T.3
Sanders, P.4
Young, S.5
Roberts, E.6
Wilmot, J.7
Hu, X.8
Kabelis, K.9
Clark, J.10
-
12
-
-
12744280744
-
Structure of human follicle-stimulating hormone in complex with its receptor
-
(doi:10.1038/nature03206)
-
Fan QR & Hendrickson WA 2005 Structure of human follicle-stimulating hormone in complex with its receptor. Nature 433 269-277. (doi:10.1038/nature03206)
-
(2005)
Nature
, vol.433
, pp. 269-277
-
-
Fan, Q.R.1
Hendrickson, W.A.2
-
13
-
-
0036963754
-
Characterization of the thyrotropin binding pocket
-
(doi:10. 1089/105072502321085144)
-
Jeffreys J, Depraetere H, Sanders J, Oda Y, Evans M, Kiddie A, Richards T, Furmaniak J & Rees Smith B 2002 Characterization of the thyrotropin binding pocket. Thyroid 12 1051-1061. (doi:10. 1089/105072502321085144)
-
(2002)
Thyroid
, vol.12
, pp. 1051-1061
-
-
Jeffreys, J.1
Depraetere, H.2
Sanders, J.3
Oda, Y.4
Evans, M.5
Kiddie, A.6
Richards, T.7
Furmaniak, J.8
Smith, B.R.9
-
14
-
-
0030028728
-
Principles of protein-protein interactions
-
(doi:10.1073/pnas.93.1.13)
-
Jones S & Thornton JM 1996 Principles of protein-protein interactions. PNAS 93 13-20. (doi:10.1073/pnas.93.1.13)
-
(1996)
PNAS
, vol.93
, pp. 13-20
-
-
Jones, S.1
Thornton, J.M.2
-
15
-
-
0029937902
-
Epitopes for thyroid-stimulating antibodies in Graves' sera: A possible link of heterogeneity to differences in response to antithyroid drug treatment
-
(doi:10.1210/jc.81.5.1758)
-
Kim WB, Cho BY, Park HY, Lee HK, Kohn LD, Tahara K & Koh C 1996 Epitopes for thyroid-stimulating antibodies in Graves' sera: a possible link of heterogeneity to differences in response to antithyroid drug treatment. Journal of Clinical Endocrinology and Metabolism 81 1758-1767. (doi:10.1210/jc.81.5.1758)
-
(1996)
Journal of Clinical Endocrinology and Metabolism
, vol.81
, pp. 1758-1767
-
-
Kim, W.B.1
Cho, B.Y.2
Park, H.Y.3
Lee, H.K.4
Kohn, L.D.5
Tahara, K.6
Koh, C.7
-
16
-
-
0031154048
-
Changes in epitopes for thyroid-stimulating antibodies in Graves' disease sera during treatment of hyperthyroidism: Therapeutic implications
-
(doi:10.1210/jc.82.6.1953)
-
Kim WB, Chung HK, Lee HK, Kohn LD, Tahara K & Cho BY 1997 Changes in epitopes for thyroid-stimulating antibodies in Graves' disease sera during treatment of hyperthyroidism: therapeutic implications. Journal of Clinical Endocrinology and Metabolism 82 1953-1959. (doi:10.1210/jc.82.6.1953)
-
(1997)
Journal of Clinical Endocrinology and Metabolism
, vol.82
, pp. 1953-1959
-
-
Kim, W.B.1
Chung, H.K.2
Lee, H.K.3
Kohn, L.D.4
Tahara, K.5
Cho, B.Y.6
-
17
-
-
48749099119
-
Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor
-
(doi:10.1096/fj.07-104711)
-
Kleinau G, Jaeschke H, Mueller S, Raaka BM, Neumann S, Paschke R & Krause G 2008 Evidence for cooperative signal triggering at the extracellular loops of the TSH receptor. FASEB Journal 22 2798-2808. (doi:10.1096/fj.07-104711)
-
(2008)
FASEB Journal
, vol.22
, pp. 2798-2808
-
-
Kleinau, G.1
Jaeschke, H.2
Mueller, S.3
Raaka, B.M.4
Neumann, S.5
Paschke, R.6
Krause, G.7
-
18
-
-
0027532027
-
Identification of thyroid antibody-specific interaction sites in the N-terminal region of the thyrotropin receptor
-
doi:10.1210/me.7.1.114
-
Kosugi S, Ban T & Kohn LD 1993 Identification of thyroid antibody-specific interaction sites in the N-terminal region of the thyrotropin receptor. MolecularEndocrinology 7 114-130.(doi:10.1210/me.7.1.114)
-
(1993)
MolecularEndocrinology
, vol.7
, pp. 114-130
-
-
Kosugi, S.1
Ban, T.2
Kohn, L.D.3
-
19
-
-
0034886412
-
Epitope mapping of TSH receptor-blocking antibodies in Graves' disease that appear during pregnancy
-
doi:10.1210/jc.86.8.3647
-
Kung AWC, Lau KS & Kohn LD 2001 Epitope mapping of TSH receptor-blocking antibodies in Graves' disease that appear during pregnancy. Journal of Clinical Endocrinology and Metabolism 86 3647-3653. (doi:10.1210/jc.86.8.3647)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, pp. 3647-3653
-
-
Kung, A.W.C.1
Lau, K.S.2
Kohn, L.D.3
-
20
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T5
-
(doi:10.1038/ 227680a0)
-
Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T5. Nature 227 680-684. (doi:10.1038/ 227680a0)
-
(1970)
Nature
, vol.227
, pp. 680-684
-
-
Laemmli, U.K.1
-
22
-
-
62749104387
-
The thyroid stimulating hormone receptor: Impact of thyroid-stimulating hormone and thyroid stimulating hormone receptor antibodies on multimerisation, cleavage, and signaling
-
(doi:10.1016/j.ecl.2009.01.006)
-
Latif R, Morshed SA, Zaidi M & Davies TF 2009 The thyroid stimulating hormone receptor: impact of thyroid-stimulating hormone and thyroid stimulating hormone receptor antibodies on multimerisation, cleavage, and signaling. Endocrinology and Metabolism Clinics of North America 38 319-341. (doi:10.1016/j.ecl.2009.01.006)
-
(2009)
Endocrinology and Metabolism Clinics of North America
, vol.38
, pp. 319-341
-
-
Latif, R.1
Morshed, S.A.2
Zaidi, M.3
Davies, T.F.4
-
23
-
-
0015222647
-
The interpretation of protein structures: Estimation of static accessibility
-
doi:10.1016/0022-2836(71)90324-X
-
Lee B & Richards FM 1971 The interpretation of protein structures: estimation of static accessibility. Journal of Molecular Biology 55 379-400. (doi:10.1016/0022-2836(71)90324-X)
-
(1971)
Journal of Molecular Biology
, vol.55
, pp. 379-400
-
-
Lee, B.1
Richards, F.M.2
-
24
-
-
0003187567
-
The atomic structure of protein-protein recognition sites
-
(doi:10.1006/jmbi.1998.2439)
-
Lo Conte L, Chothia C & Janin J 1999 The atomic structure of protein-protein recognition sites. Journal of Molecular Biology 285 2177-2198. (doi:10.1006/jmbi.1998.2439)
-
(1999)
Journal of Molecular Biology
, vol.285
, pp. 2177-2198
-
-
Conte, L.L.1
Chothia, C.2
Janin, J.3
-
25
-
-
79953676642
-
Direct assay of TSH receptor autoantibodies causing Graves' disease correlates with the clinical diagnosis closer than assays based on TSH displacement
-
Supplement
-
Loos U, Franz C, Minich WB & Büsselmann I 2007 Direct assay of TSH receptor autoantibodies causing Graves' disease correlates with the clinical diagnosis closer than assays based on TSH displacement. Hormone Research 68 (Supplement 3) 21-91.
-
(2007)
Hormone Research
, vol.68
, Issue.3
, pp. 21-91
-
-
Loos, U.1
Franz, C.2
Minich, W.B.3
Büsselmann, I.4
-
26
-
-
0026751981
-
Fetal and neonatal hyperthyroidism and hypothyroidism due to maternal TSH receptor antibodies
-
(doi:10.1089/thy.1992.2.155)
-
McKenzie JM & Zakarija M 1992 Fetal and neonatal hyperthyroidism and hypothyroidism due to maternal TSH receptor antibodies. Thyroid 2 155-159. (doi:10.1089/thy.1992.2.155)
-
(1992)
Thyroid
, vol.2
, pp. 155-159
-
-
McKenzie, J.M.1
Zakarija, M.2
-
27
-
-
0029795598
-
Monoclonal, human autoanti-bodies to the TSH receptor-the holy grail and why are we looking for it
-
(doi:10.1210/jc.81.9.3152)
-
McLachlan SM & Rapoport B 1996 Monoclonal, human autoanti-bodies to the TSH receptor-the holy grail and why are we looking for it? Journal of Clinical Endocrinology and Metabolism 81 3152-3154. (doi:10.1210/jc.81.9.3152)
-
(1996)
Journal of Clinical Endocrinology and Metabolism
, vol.81
, pp. 3152-3154
-
-
McLachlan, S.M.1
Rapoport, B.2
-
28
-
-
0034056124
-
Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis
-
(doi:10.1055/s-2000-5804)
-
Minich WB & Loos U 2000 Detection of functionally different types of pathological autoantibodies against thyrotropin receptor in Graves' patients sera by luminescent immunoprecipitation analysis. Experimental and Clinical Endocrinology and Diabetes 108 110-119. (doi:10.1055/s-2000-5804)
-
(2000)
Experimental and Clinical Endocrinology and Diabetes
, vol.108
, pp. 110-119
-
-
Minich, W.B.1
Loos, U.2
-
30
-
-
43049109876
-
The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction
-
(doi:10.1210/ me.2007-0407)
-
Mizutori Y, Chen CR, McLachan SM & Rapoport B 2008 The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction. Molecular Endocrinology 22 1171-1182. (doi:10.1210/ me.2007-0407)
-
(2008)
Molecular Endocrinology
, vol.22
, pp. 1171-1182
-
-
Mizutori, Y.1
Chen, C.R.2
McLachan, S.M.3
Rapoport, B.4
-
31
-
-
0345275971
-
Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum
-
(doi:10.1016/ j.mce.2003.09.018)
-
Morganthaler NG, Minich WB, Willnich M, Bogusch T, Hollidt JM, Weglohner W, Lenzner C & Bergmann A 2003 Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum. Molecular and Cellular Endocrinology 212 73-79. (doi:10.1016/ j.mce.2003.09.018)
-
(2003)
Molecular and Cellular Endocrinology
, vol.212
, pp. 73-79
-
-
Morganthaler, N.G.1
Minich, W.B.2
Willnich, M.3
Bogusch, T.4
Hollidt, J.M.5
Weglohner, W.6
Lenzner, C.7
Bergmann, A.8
-
32
-
-
33947496301
-
Stimulating and blocking thyroid stimulating hormone (TSH) receptor autoantibodies from patients with Graves' disease and autoimmune hypothyroidism have very similar concentration, TSH receptor affinity, and binding sites
-
(doi:10.1210/jc.2006-2213)
-
Morganthaler NG, Ho SC & Minich WB 2007 Stimulating and blocking thyroid stimulating hormone (TSH) receptor autoantibodies from patients with Graves' disease and autoimmune hypothyroidism have very similar concentration, TSH receptor affinity, and binding sites. Journal of Clinical Endocrinology and Metabolism 92 1058-1065. (doi:10.1210/jc.2006-2213)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, pp. 1058-1065
-
-
Morganthaler, N.G.1
Ho, S.C.2
Minich, W.B.3
-
33
-
-
49649125175
-
Extended hormone binding site of the human thyroid stimulating hormone receptor
-
(doi:10.1074/jbc.M800449200)
-
Mueller S, Kleinau G, Jaeschke H, Paschke R & Krause G 2008 Extended hormone binding site of the human thyroid stimulating hormone receptor. Journal of Biological Chemistry 283 18048-18055. (doi:10.1074/jbc.M800449200)
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 18048-18055
-
-
Mueller, S.1
Kleinau, G.2
Jaeschke, H.3
Paschke, R.4
Krause, G.5
-
34
-
-
0025831943
-
Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors
-
(doi:10.1172/JCI115297)
-
Nagayama Y, Wadsworth HL, Russo D, Chazenbalk GD & Rapoport B 1991 Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors. Journal of Clinical Investigation 88 336-340. (doi:10.1172/JCI115297)
-
(1991)
Journal of Clinical Investigation
, vol.88
, pp. 336-340
-
-
Nagayama, Y.1
Wadsworth, H.L.2
Russo, D.3
Chazenbalk, G.D.4
Rapoport, B.5
-
35
-
-
33845244176
-
Estimation of serum TSH receptor autoantibody concentration and affinity
-
(doi:10.1089/thy.2006.16. 1077)
-
Nakatake N, Sanders J, Richards T, Burne P, Barrett C, Dal Pra C, Presotto F, Betterle C, Furmaniak J & Rees Smith B 2006 Estimation of serum TSH receptor autoantibody concentration and affinity. Thyroid 16 1077-1084. (doi:10.1089/thy.2006.16. 1077)
-
(2006)
Thyroid
, vol.16
, pp. 1077-1084
-
-
Nakatake, N.1
Sanders, J.2
Richards, T.3
Burne, P.4
Barrett, C.5
Pra, C.D.6
Presotto, F.7
Betterle, C.8
Furmaniak, J.9
Smith, B.R.10
-
36
-
-
55749106015
-
FSH and TSH binding to their respective receptors: Similarities, differences and implication for glycoprotein hormone specificity
-
(doi:10.1677/JME-08-0040)
-
Núñez Miguel R, Sanders J, Chirgadze DY, Blundell TL, Furmaniak J & Rees Smith B 2008 FSH and TSH binding to their respective receptors: similarities, differences and implication for glycoprotein hormone specificity. Journal of Molecular Endocrinology 41 145-164. (doi:10.1677/JME-08-0040)
-
(2008)
Journal of Molecular Endocrinology
, vol.41
, pp. 145-164
-
-
Núñez, M.R.1
Sanders, J.2
Chirgadze, D.Y.3
Blundell, T.L.4
Furmaniak, J.5
Smith, B.R.6
-
37
-
-
67649361912
-
Thyroid stimulating autoantibody M22 mimics TSH binding to the TSH receptor leucine rich domain: A comparative structural study of protein-protein interactions
-
(doi:10.1677/JME-08-0152)
-
Núñez Miguel R, Sanders J, Chirgadze DY, Furmaniak J & Rees Smith B 2009 Thyroid stimulating autoantibody M22 mimics TSH binding to the TSH receptor leucine rich domain: a comparative structural study of protein-protein interactions. Journal of Molecular Endocrinology 42 381-395. (doi:10.1677/JME-08-0152)
-
(2009)
Journal of Molecular Endocrinology
, vol.42
, pp. 381-395
-
-
Núñez, M.R.1
Sanders, J.2
Chirgadze, D.Y.3
Furmaniak, J.4
Smith, B.R.5
-
38
-
-
0025275610
-
On the nature of antibody combining sites. Unusual structural features that may confer on these sites an enhanced capacity for binding ligands
-
(doi:10.1002/prot. 340070203)
-
Padlan EA 1990 On the nature of antibody combining sites. Unusual structural features that may confer on these sites an enhanced capacity for binding ligands. Proteins 7 112-124. (doi:10.1002/prot. 340070203)
-
(1990)
Proteins
, vol.7
, pp. 112-124
-
-
Padlan, E.A.1
-
39
-
-
0032247323
-
The thyrotropin (TSH) receptor: Interaction with TSH and autoanti-bodies
-
(doi:10.1210/er.19.6.673)
-
Rapoport B, Chazenbalk GD, Jaume JC & McLachlan SM 1998 The thyrotropin (TSH) receptor: interaction with TSH and autoanti-bodies. Endocrine Reviews 19 673-716. (doi:10.1210/er.19.6.673)
-
(1998)
Endocrine Reviews
, vol.19
, pp. 673-716
-
-
Rapoport, B.1
Chazenbalk, G.D.2
Jaume, J.C.3
McLachlan, S.M.4
-
40
-
-
0023956698
-
Autoantibodies to the thyrotropin receptor
-
(doi:10. 1210/edrv-9-1-106)
-
Rees Smith B, McLachlan SM & Furmaniak J 1988 Autoantibodies to the thyrotropin receptor. Endocrine Reviews 9 106-121. (doi:10. 1210/edrv-9-1-106)
-
(1988)
Endocrine Reviews
, vol.9
, pp. 106-121
-
-
Smith, B.R.1
McLachlan, S.M.2
Furmaniak, J.3
-
41
-
-
35948945305
-
TSH receptor antibodies
-
(doi:10.1089/thy.2007.0239)
-
Rees Smith B, Sanders J & Furmaniak J 2007 TSH receptor antibodies. Thyroid 17 923-938. (doi:10.1089/thy.2007.0239)
-
(2007)
Thyroid
, vol.17
, pp. 923-938
-
-
Smith, B.R.1
Sanders, J.2
Furmaniak, J.3
-
42
-
-
68149160223
-
TSH receptor-autoantibody interactions
-
(doi:10.1055/s-0029-1220913)
-
Rees Smith B, Sanders J, Evans M, Tagami T & Furmaniak J 2009 TSH receptor-autoantibody interactions. Hormone and Metabolic Research 41 448-455. (doi:10.1055/s-0029-1220913)
-
(2009)
Hormone and Metabolic Research
, vol.41
, pp. 448-455
-
-
Smith, B.R.1
Sanders, J.2
Evans, M.3
Tagami, T.4
Furmaniak, J.5
-
43
-
-
0021755764
-
Solvent accessible surface area excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect
-
doi:10.1016/0022-2836(84)90231-6
-
Richmond TJ 1984 Solvent accessible surface area excluded volume in proteins. Analytical equations for overlapping spheres and implications for the hydrophobic effect. Journal of Molecular Biology 178 63-89. (doi:10.1016/0022-2836(84)90231-6)
-
(1984)
Journal of Molecular Biology
, vol.178
, pp. 63-89
-
-
Richmond, T.J.1
-
44
-
-
0031408669
-
Understanding the thyrotropin receptor function-structure relationship
-
doi:10.1016/S0950-351X(97)80693-3
-
Sanders J,Oda Y, Roberts SA, Maruyama M, Furmaniak J & Rees Smith B 1997 Understanding the thyrotropin receptor function-structure relationship. Baillière's Clinical Endocrinology and Metabolism 11 451-479. (doi:10.1016/S0950-351X(97)80693-3)
-
(1997)
Baillière's Clinical Endocrinology and Metabolism
, vol.11
, pp. 451-479
-
-
Sanders, J.1
-
45
-
-
0033305013
-
125I-labelled TSH receptor
-
(doi:10.1210/jc.84.10.3797)
-
125I-labelled TSH receptor. Journal of Clinical Endocrinology and Metabolism 84 3797-3802. (doi:10.1210/jc.84.10.3797)
-
(1999)
Journal of Clinical Endocrinology and Metabolism
, vol.84
, pp. 3797-3802
-
-
Sanders, J.1
Oda, Y.2
Roberts, S.3
Kiddie, A.4
Richards, T.5
Bolton, J.6
McGrath, V.7
Walters, S.8
Jaskólski, D.9
Furmaniak, J.10
-
46
-
-
12244265471
-
Thyroid stimulating monoclonal antibodies
-
(doi:10. 1089/105072502321085135)
-
Sanders J, Jeffreys J, Depraetere H, Richards T, Evans M, Kiddie A, Brereton K, Groenen M, Oda Y, Furmaniak J et al. 2002 Thyroid stimulating monoclonal antibodies. Thyroid 12 1043-1050. (doi:10. 1089/105072502321085135)
-
(2002)
Thyroid
, vol.12
, pp. 1043-1050
-
-
Sanders, J.1
Jeffreys, J.2
Depraetere, H.3
Richards, T.4
Evans, M.5
Kiddie, A.6
Brereton, K.7
Groenen, M.8
Oda, Y.9
Furmaniak, J.10
-
47
-
-
0037967531
-
Human monoclonal thyroid stimulating autoantibody
-
doi:10. 1016/S0140-6736(03)13866-4
-
Sanders J, Evans M, Premawardhana LDKE, Depraetere H, Jeffreys J, Richards T, Furmaniak J & Rees Smith B 2003 Human monoclonal thyroid stimulating autoantibody. Lancet 362 126-128. (doi:10. 1016/S0140-6736(03)13866-4)
-
(2003)
Lancet
, vol.362
, pp. 126-128
-
-
Sanders, J.1
Evans, M.2
Premawardhana, L.D.K.E.3
Depraetere, H.4
Jeffreys, J.5
Richards, T.6
Furmaniak, J.7
Smith, B.R.8
-
48
-
-
4143063483
-
Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: Sequence structure and function
-
(doi:10.1089/1050725041692918)
-
Sanders J, Jeffreys J, Depraetere H, Evans M, Richards T, Kiddie A, Brereton K, Premawardhana LD, Chirgadze DY, Núñez Miguel R et al. 2004 Characteristics of a human monoclonal autoantibody to the thyrotropin receptor: sequence structure and function. Thyroid 14 560-570. (doi:10.1089/1050725041692918)
-
(2004)
Thyroid
, vol.14
, pp. 560-570
-
-
Sanders, J.1
Jeffreys, J.2
Depraetere, H.3
Evans, M.4
Richards, T.5
Kiddie, A.6
Brereton, K.7
Premawardhana, L.D.8
Chirgadze, D.Y.9
Núñez, M.R.10
-
49
-
-
23644454099
-
Characteristics of a monoclonal antibody to the thyrotropin receptor that acts as a powerful thyroid-stimulating autoantibody antagonist
-
doi:10.1089/thy.2005.15.672
-
Sanders J, Allen F, Jeffreys J, Bolton J, Richards T, Depraetere H, Nakatake N, Evans M, Kiddie A, Premawardhana LDKE et al. 2005 Characteristics of a monoclonal antibody to the thyrotropin receptor that acts as a powerful thyroid-stimulating autoantibody antagonist. Thyroid 15 672-682. (doi:10.1089/thy.2005.15.672)
-
(2005)
Thyroid
, vol.15
, pp. 672-682
-
-
Sanders, J.1
Allen, F.2
Jeffreys, J.3
Bolton, J.4
Richards, T.5
Depraetere, H.6
Nakatake, N.7
Evans, M.8
Kiddie, A.9
Premawardhana, L.D.K.E.10
-
50
-
-
33846156211
-
Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH
-
(doi:10. 1089/thy.2006.16.1195)
-
Sanders J, Bolton J, Sanders P, Jeffreys J, Nakatake N, Richards T, Evans M, Kiddie A, Summerhayes S, Roberts E et al. 2006 Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH. Thyroid 16 1195-1206. (doi:10. 1089/thy.2006.16.1195)
-
(2006)
Thyroid
, vol.16
, pp. 1195-1206
-
-
Sanders, J.1
Bolton, J.2
Sanders, P.3
Jeffreys, J.4
Nakatake, N.5
Richards, T.6
Evans, M.7
Kiddie, A.8
Summerhayes, S.9
Roberts, E.10
-
51
-
-
34249941108
-
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
-
(doi:10.1089/thy.2007.0034)
-
Sanders J, Chirgadze DY, Sanders P, Baker S, Sullivan A, Bhardwaja A, Bolton J, Reeve M, Nakatake N, Evans M et al. 2007a Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody. Thyroid 17 395-410. (doi:10.1089/thy.2007.0034)
-
(2007)
Thyroid
, vol.17
, pp. 395-410
-
-
Sanders, J.1
Chirgadze, D.Y.2
Sanders, P.3
Baker, S.4
Sullivan, A.5
Bhardwaja, A.6
Bolton, J.7
Reeve, M.8
Nakatake, N.9
Evans, M.10
-
52
-
-
35948937324
-
Molecular interactions between the TSH receptor and a thyroid-stimulating monoclonal autoantibody
-
(doi:10.1089/thy.2007.0041)
-
Sanders J, Núñez Miguel R, Bolton J, Bhardwaja A, Sanders P, Nakatake N, Evans M, Furmaniak J & Rees Smith B 2007b Molecular interactions between the TSH receptor and a thyroid-stimulating monoclonal autoantibody. Thyroid 17 699-706. (doi:10.1089/thy.2007.0041)
-
(2007)
Thyroid
, vol.17
, pp. 699-706
-
-
Sanders, J.1
Núñez, M.R.2
Bolton, J.3
Bhardwaja, A.4
Sanders, P.5
Nakatake, N.6
Evans, M.7
Furmaniak, J.8
Smith, B.R.9
-
53
-
-
47549103701
-
A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity
-
(doi:10.1089/thy. 2007.0327)
-
Sanders J, Evans M, Betterle C, Sanders P, Bhardwaja A, Young S, Roberts E, Wilmot J, Richards T, Kiddie A et al. 2008 A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity. Thyroid 18 735-746. (doi:10.1089/thy. 2007.0327)
-
(2008)
Thyroid
, vol.18
, pp. 735-746
-
-
Sanders, J.1
Evans, M.2
Betterle, C.3
Sanders, P.4
Bhardwaja, A.5
Young, S.6
Roberts, E.7
Wilmot, J.8
Richards, T.9
Kiddie, A.10
-
54
-
-
0036198831
-
Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor
-
(doi:10.1089/105072502753522347)
-
Schwarz-Lauer L, Chazenbalk GD, McLachlan SM, Ochi Y, Nagayama Y & Rapoport B 2002 Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor. Thyroid 12 115-120. (doi:10.1089/105072502753522347)
-
(2002)
Thyroid
, vol.12
, pp. 115-120
-
-
Schwarz-Lauer, L.1
Chazenbalk, G.D.2
McLachlan, S.M.3
Ochi, Y.4
Nagayama, Y.5
Rapoport, B.6
-
55
-
-
0025951486
-
Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients
-
(doi:10.1016/0006-291X(91)91335-A)
-
Tahara K,Ban T,Minegishi T and Kohn LD 1991 Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients. Biochemical and Biophysical Research Communications 179 70-77. (doi:10.1016/0006-291X(91)91335-A)
-
(1991)
Biochemical and Biophysical Research Communications
, vol.179
, pp. 70-77
-
-
Tahara, K.1
Ban, T.2
Minegishi, T.3
Kohn, L.D.4
-
56
-
-
0031463319
-
Epitopes for thyroid stimulating and thyroid blocking autoantibodies on the extracellular domain of the human thyrotropin receptor
-
(doi:10.1089/thy. 1997.7.867)
-
Tahara K, Ishikawa N, Yamamoto K, Hirai A, Ito K, Tamura Y, Yoshida S, Saito Y & Kohn LD 1997 Epitopes for thyroid stimulating and thyroid blocking autoantibodies on the extracellular domain of the human thyrotropin receptor. Thyroid 7 867-877. (doi:10.1089/thy. 1997.7.867)
-
(1997)
Thyroid
, vol.7
, pp. 867-877
-
-
Tahara, K.1
Ishikawa, N.2
Yamamoto, K.3
Hirai, A.4
Ito, K.5
Tamura, Y.6
Yoshida, S.7
Saito, Y.8
Kohn, L.D.9
-
57
-
-
34547460183
-
Molecular evolution of affinity and flexibility in the immune system
-
(doi:10. 1073/pnas.0610064104)
-
Thorpe IF & Brooks CL 2007 Molecular evolution of affinity and flexibility in the immune system. PNAS 104 8821-8826. (doi:10. 1073/pnas.0610064104)
-
(2007)
PNAS
, vol.104
, pp. 8821-8826
-
-
Thorpe, I.F.1
Brooks, C.L.2
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