-
2
-
-
12244265471
-
Thyroid-stimulating monoclonal antibodies
-
Sanders J, Jeffreys J, Depraetere H, Richards T, Evans M, Kiddie A, Brereton K, Groenen M, Oda Y, Furmaniak J, Rees Smith B 2002 Thyroid-stimulating monoclonal antibodies. Thyroid 12:1043-1050
-
(2002)
Thyroid
, vol.12
, pp. 1043-1050
-
-
Sanders, J.1
Jeffreys, J.2
Depraetere, H.3
Richards, T.4
Evans, M.5
Kiddie, A.6
Brereton, K.7
Groenen, M.8
Oda, Y.9
Furmaniak, J.10
Rees Smith, B.11
-
3
-
-
0036895765
-
A monoclonal thyroid-stimulating antibody
-
Ando T, Latif R, Pritsker A, Moran T, Nagayama Y, Davies TF 2002 A monoclonal thyroid-stimulating antibody. J Clin Invest 110:1667-1674
-
(2002)
J Clin Invest
, vol.110
, pp. 1667-1674
-
-
Ando, T.1
Latif, R.2
Pritsker, A.3
Moran, T.4
Nagayama, Y.5
Davies, T.F.6
-
4
-
-
0036921438
-
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity
-
Costagliola S, Franssen JD, Bonomi M, Urizar E, Willnich M, Bergmann A, Vassart G 2002 Generation of a mouse monoclonal TSH receptor antibody with stimulating activity. Biochem Biophys Res Commun 299:891-896
-
(2002)
Biochem Biophys Res Commun
, vol.299
, pp. 891-896
-
-
Costagliola, S.1
Franssen, J.D.2
Bonomi, M.3
Urizar, E.4
Willnich, M.5
Bergmann, A.6
Vassart, G.7
-
5
-
-
0037967531
-
Human monoclonal thyroid stimulating autoantibody
-
Sanders J, Evans M, Premawardhana LD, Depraetere H, Jeffreys J, Richards T, Furmaniak J, Rees Smith B 2003 Human monoclonal thyroid stimulating autoantibody. Lancet 362:126-128
-
(2003)
Lancet
, vol.362
, pp. 126-128
-
-
Sanders, J.1
Evans, M.2
Premawardhana, L.D.3
Depraetere, H.4
Jeffreys, J.5
Richards, T.6
Furmaniak, J.7
Rees Smith, B.8
-
6
-
-
9644295678
-
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity
-
Costagliola S, Bonomi M, Morgenthaler NG, Van Durme J, Panneels V, Refetoff S, Vassart G 2004 Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol 18:3020-3034
-
(2004)
Mol Endocrinol
, vol.18
, pp. 3020-3034
-
-
Costagliola, S.1
Bonomi, M.2
Morgenthaler, N.G.3
Van Durme, J.4
Panneels, V.5
Refetoff, S.6
Vassart, G.7
-
7
-
-
0345275971
-
Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum
-
Morgenthaler NG, Minich WB, Willnich M, Bogusch T, Hollidt JM, Weglohner W, Lenzner C, Bergmann A 2003 Affinity purification and diagnostic use of TSH receptor autoantibodies from human serum. Mol Cell Endocrinol 212:73-79
-
(2003)
Mol Cell Endocrinol
, vol.212
, pp. 73-79
-
-
Morgenthaler, N.G.1
Minich, W.B.2
Willnich, M.3
Bogusch, T.4
Hollidt, J.M.5
Weglohner, W.6
Lenzner, C.7
Bergmann, A.8
-
8
-
-
0032807561
-
Differences in the levels of TSH-binding inhibitor immunoglobulins in goitrous and agoitrous autoimmune thyroiditis after twelve months of l-thyroxine therapy
-
Khoo DH, Eng PH, Ho SC, Fok AC 1999 Differences in the levels of TSH-binding inhibitor immunoglobulins in goitrous and agoitrous autoimmune thyroiditis after twelve months of l-thyroxine therapy. Clin Endocrinol (Oxf) 51:73-79
-
(1999)
Clin Endocrinol (Oxf)
, vol.51
, pp. 73-79
-
-
Khoo, D.H.1
Eng, P.H.2
Ho, S.C.3
Fok, A.C.4
-
9
-
-
0032902454
-
Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease
-
Costagliola S, Morgenthaler NG, Hoermann R, Badenhoop K, Struck J, Freitag D, Poertl S, Weglohner W, Hollidt JM, Quadbeck B, Dumont JE, Schumm-Draeger PM, Bergmann A, Mann K, Vassart G, Usadel KH 1999 Second generation assay for thyrotropin receptor antibodies has superior diagnostic sensitivity for Graves' disease. J Clin Endocrinol Metab 84:90-97
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 90-97
-
-
Costagliola, S.1
Morgenthaler, N.G.2
Hoermann, R.3
Badenhoop, K.4
Struck, J.5
Freitag, D.6
Poertl, S.7
Weglohner, W.8
Hollidt, J.M.9
Quadbeck, B.10
Dumont, J.E.11
Schumm-Draeger, P.M.12
Bergmann, A.13
Mann, K.14
Vassart, G.15
Usadel, K.H.16
-
10
-
-
0033753758
-
Detecting TSH-receptor antibodies with the recombinant TBII assay: Technical and clinical evaluation
-
Schott M, Feldkamp J, Bathan C, Fritzen R, Scherbaum WA, Seissler J 2000 Detecting TSH-receptor antibodies with the recombinant TBII assay: technical and clinical evaluation. Horm Metab Res 32:429-435
-
(2000)
Horm Metab Res
, vol.32
, pp. 429-435
-
-
Schott, M.1
Feldkamp, J.2
Bathan, C.3
Fritzen, R.4
Scherbaum, W.A.5
Seissler, J.6
-
11
-
-
0031945537
-
Application of a bioassay with CHO cells for the routine detection of stimulating and blocking autoantibodies to the TSH-receptor
-
Morgenthaler NG, Pampel I, Aust G, Seissler J, Scherbaum WA 1998 Application of a bioassay with CHO cells for the routine detection of stimulating and blocking autoantibodies to the TSH-receptor. Horm Metab Res 30:162-168
-
(1998)
Horm Metab Res
, vol.30
, pp. 162-168
-
-
Morgenthaler, N.G.1
Pampel, I.2
Aust, G.3
Seissler, J.4
Scherbaum, W.A.5
-
12
-
-
0025159836
-
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones
-
Perret J, Ludgate M, Libert F, Gerard C, Dumont JE, Vassart G, Parmentier M 1990 Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones. Biochem Biophys Res Commun 171:1044-1050
-
(1990)
Biochem Biophys Res Commun
, vol.171
, pp. 1044-1050
-
-
Perret, J.1
Ludgate, M.2
Libert, F.3
Gerard, C.4
Dumont, J.E.5
Vassart, G.6
Parmentier, M.7
-
13
-
-
0034281466
-
Development of serum-free bioreactor production of recombinant human thyroid stimulating hormone receptor
-
Stiens LR, Buntemeyer H, Lutkemeyer D, Lehmann J, Bergmann A, Weglohner W 2000 Development of serum-free bioreactor production of recombinant human thyroid stimulating hormone receptor. Biotechnol Prog 16:703-709
-
(2000)
Biotechnol Prog
, vol.16
, pp. 703-709
-
-
Stiens, L.R.1
Buntemeyer, H.2
Lutkemeyer, D.3
Lehmann, J.4
Bergmann, A.5
Weglohner, W.6
-
14
-
-
84969001783
-
The attraction of proteins for small molecules and ions
-
Scatchard G 1949 The attraction of proteins for small molecules and ions. Ann NY Acad Sci 51:600-672
-
(1949)
Ann NY Acad Sci
, vol.51
, pp. 600-672
-
-
Scatchard, G.1
-
15
-
-
0029645408
-
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats
-
Kajava AV, Vassart G, Wodak SJ 1995 Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure 3:867-877
-
(1995)
Structure
, vol.3
, pp. 867-877
-
-
Kajava, A.V.1
Vassart, G.2
Wodak, S.J.3
-
16
-
-
10944228424
-
Identification of a novel epitope in the TSH receptor ectodomain acting as intramolecular signalling interface
-
Kleinau G, Jaeschke H, Neumann S, Laettig J, Paschke R, Krause G 2004 Identification of a novel epitope in the TSH receptor ectodomain acting as intramolecular signalling interface. J Biol Chem 279:51590-51600
-
(2004)
J Biol Chem
, vol.279
, pp. 51590-51600
-
-
Kleinau, G.1
Jaeschke, H.2
Neumann, S.3
Laettig, J.4
Paschke, R.5
Krause, G.6
-
17
-
-
11344254774
-
Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling
-
Nunez Miguel R, Sanders J, Jeffreys J, Depraetere H, Evans M, Richards T, Blundell TL, Rees Smith B, Furmaniak J 2004 Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling. Thyroid 14:991-1011
-
(2004)
Thyroid
, vol.14
, pp. 991-1011
-
-
Nunez Miguel, R.1
Sanders, J.2
Jeffreys, J.3
Depraetere, H.4
Evans, M.5
Richards, T.6
Blundell, T.L.7
Rees Smith, B.8
Furmaniak, J.9
-
18
-
-
0030752377
-
Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera
-
Chazenbalk GD, Jaume JC, McLachlan SM, Rapoport B 1997 Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera. J Biol Chem 272:18959-18965
-
(1997)
J Biol Chem
, vol.272
, pp. 18959-18965
-
-
Chazenbalk, G.D.1
Jaume, J.C.2
McLachlan, S.M.3
Rapoport, B.4
-
19
-
-
0035928771
-
Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor
-
Cornelis S, Uttenweiler-Joseph S, Panneels V, Vassart G, Costagliola S 2001 Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor. Biochemistry 40:9860-9869
-
(2001)
Biochemistry
, vol.40
, pp. 9860-9869
-
-
Cornelis, S.1
Uttenweiler-Joseph, S.2
Panneels, V.3
Vassart, G.4
Costagliola, S.5
-
20
-
-
0025831943
-
Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors
-
Nagayama Y, Wadsworth HL, Russo D, Chazenbalk GD, Rapoport B 1991 Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors. J Clin Invest 88:336-340
-
(1991)
J Clin Invest
, vol.88
, pp. 336-340
-
-
Nagayama, Y.1
Wadsworth, H.L.2
Russo, D.3
Chazenbalk, G.D.4
Rapoport, B.5
-
21
-
-
0027260342
-
Use of thyrotropin receptor (TSHR) mutants to detect stimulating TSHR antibodies in hypothyroid patients with idiopathic myxedema, who have blocking TSHR antibodies
-
Kosugi S, Ban T, Akamizu T, Valente W, Kohn LD 1993 Use of thyrotropin receptor (TSHR) mutants to detect stimulating TSHR antibodies in hypothyroid patients with idiopathic myxedema, who have blocking TSHR antibodies. J Clin Endocrinol Metab 77:19-24
-
(1993)
J Clin Endocrinol Metab
, vol.77
, pp. 19-24
-
-
Kosugi, S.1
Ban, T.2
Akamizu, T.3
Valente, W.4
Kohn, L.D.5
-
22
-
-
0036198831
-
Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor
-
Schwarz-Lauer L, Chazenbalk GD, McLachlan SM, Ochi Y, Nagayama Y, Rapoport B 2002 Evidence for a simplified view of autoantibody interactions with the thyrotropin receptor. Thyroid 12:115-120
-
(2002)
Thyroid
, vol.12
, pp. 115-120
-
-
Schwarz-Lauer, L.1
Chazenbalk, G.D.2
McLachlan, S.M.3
Ochi, Y.4
Nagayama, Y.5
Rapoport, B.6
-
24
-
-
1842611681
-
Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor
-
Minich WB, Lenzner C, Morgenthaler NG 2004 Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor. Clin Exp Immunol 136:129-136
-
(2004)
Clin Exp Immunol
, vol.136
, pp. 129-136
-
-
Minich, W.B.1
Lenzner, C.2
Morgenthaler, N.G.3
-
25
-
-
9244245203
-
Dissecting linear and conformational epitopes on the native thyrotropin receptor
-
Ando T, Latif R, Daniel S, Eguchi K, Davies TF 2004 Dissecting linear and conformational epitopes on the native thyrotropin receptor. Endocrinology 145:5185-5193
-
(2004)
Endocrinology
, vol.145
, pp. 5185-5193
-
-
Ando, T.1
Latif, R.2
Daniel, S.3
Eguchi, K.4
Davies, T.F.5
-
26
-
-
0038182549
-
Glycoprotein hormone receptors: Determinants in leucine-rich repeats responsible for ligand specificity
-
Smits G, Campillo M, Govaerts C, Janssens V, Richter C, Vassart G, Pardo L, Costagliola S 2003 Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity. EMBO J 22:2692-2703
-
(2003)
EMBO J
, vol.22
, pp. 2692-2703
-
-
Smits, G.1
Campillo, M.2
Govaerts, C.3
Janssens, V.4
Richter, C.5
Vassart, G.6
Pardo, L.7
Costagliola, S.8
-
27
-
-
12744280744
-
Structure of human follicle-stimulating hormone in complex with its receptor
-
Fan QR, Hendrickson WA 2005 Structure of human follicle-stimulating hormone in complex with its receptor. Nature 433:269-277
-
(2005)
Nature
, vol.433
, pp. 269-277
-
-
Fan, Q.R.1
Hendrickson, W.A.2
-
28
-
-
4544336634
-
Affinity-enrichment of thyrotropin receptor autoantibodies from Graves' patients and normal individuals provides insight into their properties and possible origin from natural antibodies
-
Latrofa F, Chazenbalk GD, Pichurin P, Chen CR, McLachlan SM, Rapoport B 2004 Affinity-enrichment of thyrotropin receptor autoantibodies from Graves' patients and normal individuals provides insight into their properties and possible origin from natural antibodies. J Clin Endocrinol Metab 89:4734-4745
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4734-4745
-
-
Latrofa, F.1
Chazenbalk, G.D.2
Pichurin, P.3
Chen, C.R.4
McLachlan, S.M.5
Rapoport, B.6
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