A Full Biological Response to Autoantibodies in Graves' Disease Requires a Disulfide-bonded Loop in the Thyrotropin Receptor N Terminus Homologous to a Laminin Epidermal Growth Factor-like Domain

Journal of Biological Chemistry

Volumn 276, Issue 18, 2001, Pages 14767-14772

  Chen, Chun Rong ^b   Tanaka, Kunihiko ^b   Chazenbalk, Gregorio D ^b   McLachlan, Sandra M ^b   Rapoport, Basil ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIGENS; DISEASES; PATHOLOGY; PATIENT TREATMENT;

PATHOGENESIS;

ANTIBODIES;

AUTOANTIBODY; EPIDERMAL GROWTH FACTOR; LAMININ; THYROID STIMULATING IMMUNOGLOBULIN; THYROTROPIN; THYROTROPIN RECEPTOR; DISULFIDE;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; CHO CELL; DISULFIDE BOND; GRAVES DISEASE; HORMONE RECEPTOR INTERACTION; IMMUNOPATHOGENESIS; MOLECULAR MIMICRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; HAMSTER; HUMAN; IMMUNOLOGY; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIBODIES; CHO CELLS; CRICETINAE; DISULFIDES; EPIDERMAL GROWTH FACTOR; GRAVES DISEASE; HUMANS; LAMININ; MOLECULAR SEQUENCE DATA; RECEPTORS, THYROTROPIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035805619     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008001200     Document Type: Article

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