Electrochemistry in the mimicry of oxidative drug metabolism by cytochrome P450s

Current Drug Metabolism

Volumn 12, Issue 4, 2011, Pages 359-371

  Nouri Nigjeh, Eslam ^a   Bischoff, Rainer ^a   Bruins, Andries P ^a   Permentier, Hjalmar P ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Cytochrome P450; Drug metabolism; Electrochemistry; Electrode modification; Mass spectrometry; Mimicry; Reactive oxygen species

Indexed keywords

CARBON; CYTOCHROME P450; CYTOCHROME P450 101; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; CYTOCHROME REDUCTASE; DRUG METABOLITE; FERRIC ION; FERROUS ION; HYDROGEN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; METALLOPORPHYRIN; MYOGLOBIN; N ACETYL 1,4 BENZOQUINONE IMINE; REACTIVE OXYGEN METABOLITE; ROTIGOTINE; UNCLASSIFIED DRUG; VALPROIC ACID;

ARTICLE; BIOMIMETICS; COVALENT BOND; DEALKYLATION; DEHYDROGENATION; DRUG METABOLISM; DRUG OXIDATION; ELECTROCHEMISTRY; ELECTRODE; EPOXIDATION; FENTON REACTION; HUMAN; HYDROXYLATION; IN VIVO STUDY; MOLECULAR MIMICRY; PROTEIN ENGINEERING; REDUCTION;

EID: 79953656393     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920011795202929     Document Type: Article

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