-
1
-
-
54149085536
-
In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: Receptor-based bioassay screens
-
Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, et al. (2008) In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect 116:1203-1210.
-
(2008)
Environ Health Perspect
, vol.116
, pp. 1203-1210
-
-
Ahn, K.C.1
Zhao, B.2
Chen, J.3
Cherednichenko, G.4
Sanmarti, E.5
Denison, M.S.6
Lasley, B.7
Pessah, I.N.8
Kültz, D.9
Chang, D.P.10
-
2
-
-
0030830108
-
Metabolism of 2,4,5,2′,4′,5′-hexachlorobiphenyl (PCB153) in guinea pig
-
Ariyoshi N, Koga N, Yoshimura H, and Oguri K (1997) Metabolism of 2,4,5,2′,4′,5′-hexachlorobiphenyl (PCB153) in guinea pig. Xenobiotica 27:973-983.
-
(1997)
Xenobiotica
, vol.27
, pp. 973-983
-
-
Ariyoshi, N.1
Koga, N.2
Yoshimura, H.3
Oguri, K.4
-
3
-
-
77952510091
-
Online electrochemistry/mass spectrometry in drug metabolism studies: Principles and applications
-
Baumann A and Karst U (2010) Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications. Expert Opin Drug Metab Toxicol 6:715-731.
-
(2010)
Expert Opin Drug Metab Toxicol
, vol.6
, pp. 715-731
-
-
Baumann, A.1
Karst, U.2
-
4
-
-
0018144597
-
Biotransformation products of 3,4,4'-trichlorocarbanilide in rat, monkey, and man
-
Birch CG, Hiles RA, Eichhold TH, Jeffcoat AR, Handy RW, Hill JM, Willis SL, Hess TR, and Wall ME (1978) Biotransformation products of 3,4,4′-trichlorocarbanilide in rat, monkey, and man. Drug Metab Dispos 6:169-176. (Pubitemid 8357489)
-
(1978)
Drug Metabolism and Disposition
, vol.6
, Issue.2
, pp. 169-176
-
-
Birch, C.G.1
Hiles, R.A.2
Eichhold, T.H.3
-
5
-
-
0034068228
-
Role of quinones in toxicology
-
Bolton JL, Trush MA, Penning TM, Dryhurst G, and Monks TJ (2000) Role of quinones in toxicology. Chem Res Toxicol 13:135-160.
-
(2000)
Chem Res Toxicol
, vol.13
, pp. 135-160
-
-
Bolton, J.L.1
Trush, M.A.2
Penning, T.M.3
Dryhurst, G.4
Monks, T.J.5
-
6
-
-
40849139427
-
Triclocarban enhances testosterone action: A new type of endocrine disruptor?
-
Chen J, Ahn KC, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, and Lasley BL (2008) Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology 149:1173-1179.
-
(2008)
Endocrinology
, vol.149
, pp. 1173-1179
-
-
Chen, J.1
Ahn, K.C.2
Gee, N.A.3
Ahmed, M.I.4
Duleba, A.J.5
Zhao, L.6
Gee, S.J.7
Hammock, B.D.8
Lasley, B.L.9
-
7
-
-
0018369910
-
Effect of hexachlorophene, tribromsalan, trichlorcarban and cloflucarban on hexobarbital sleeping time and hepatic drug-metabolizing enzyme activity in vitro in the rat
-
Condie LW and Buhler DR (1979) Effect of hexachlorophene, tribromsalan, trichlorcarban and cloflucarban on hexobarbital sleeping time and hepatic drug-metabolizing enzyme activity in vitro in the rat. Biochem Pharmacol 28:375-380.
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 375-380
-
-
Condie, L.W.1
Buhler, D.R.2
-
8
-
-
54149098291
-
-
European Commission, Scientific Committee on Consumer Products Colipa no. P29. SCCP/0851/04. European Commission, Brussels, Belgium
-
European Commission, Scientific Committee on Consumer Products (2005) Opinion on triclocarban for other uses than as a preservative. Colipa no. P29. SCCP/0851/04. European Commission, Brussels, Belgium.
-
(2005)
Opinion on Triclocarban for Other Uses Than As a Preservative
-
-
-
9
-
-
1642281756
-
Drug-protein adducts: An industry perspective on minimizing the potential for drug bioactivation in drug discovery and development
-
Evans DC, Watt AP, Nicoll-Griffith DA, and Baillie TA (2004) Drug-protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development. Chem Res Toxicol 17:3-16.
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 3-16
-
-
Evans, D.C.1
Watt, A.P.2
Nicoll-Griffith, D.A.3
Baillie, T.A.4
-
10
-
-
79960129718
-
Oxidative, reductive and hydrolytic metabolism of drugs
-
(Zhang D, Zhu M, and Humphreys WG eds) Wiley & Sons Inc., Hoboken, NJ
-
Guengerich FP (2007) Oxidative, reductive and hydrolytic metabolism of drugs, in Drug Metabolism in Drug Design and Development (Zhang D, Zhu M, and Humphreys WG eds) p 265, Wiley & Sons Inc., Hoboken, NJ.
-
(2007)
Drug Metabolism in Drug Design and Development
, pp. 265
-
-
Guengerich, F.P.1
-
11
-
-
4544252329
-
Analysis of triclocarban in aquatic samples by liquid chromatography electrospray ionization mass spectrometry
-
Halden RU and Paull DH (2004) Analysis of triclocarban in aquatic samples by liquid chromatography electrospray ionization mass spectrometry. Environ Sci Technol 38:4849-4855.
-
(2004)
Environ Sci Technol
, vol.38
, pp. 4849-4855
-
-
Halden, R.U.1
Paull, D.H.2
-
12
-
-
15244355672
-
Co-occurrence of triclocarban and triclosan in U.S. water resources
-
Halden RU and Paull DH (2005) Co-occurrence of triclocarban and triclosan in U.S. water resources. Environ Sci Technol 39:1420-1426.
-
(2005)
Environ Sci Technol
, vol.39
, pp. 1420-1426
-
-
Halden, R.U.1
Paull, D.H.2
-
13
-
-
14044270107
-
Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters, and guinea pigs
-
Haraguchi K, Koga N, and Kato Y (2005) Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters, and guinea pigs. Drug Metab Dispos 33:373-380.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 373-380
-
-
Haraguchi, K.1
Koga, N.2
Kato, Y.3
-
14
-
-
0017684960
-
14C]carbanilide (TFC) in rats
-
14C]carbanilide (TFC) in rats. Food Cosmet Toxicol 15:205-211.
-
(1977)
Food Cosmet Toxicol
, vol.15
, pp. 205-211
-
-
Hiles, R.A.1
-
15
-
-
0018098526
-
The absorption, excretion, and biotransformation of 3,4,4′- trichlorocarbanilide in humans
-
Hiles RA and Birch CG (1978a) The absorption, excretion, and biotransformation of 3,4,4′-trichlorocarbanilide in humans. Drug Metab Dispos 6:177-183.
-
(1978)
Drug Metab Dispos
, vol.6
, pp. 177-183
-
-
Hiles, R.A.1
Birch, C.G.2
-
16
-
-
0018081244
-
Nonlinear metabolism and disposition of 3,4,4′-trichlorocarbanilide in the rat
-
Hiles RA and Birch CG (1978b) Nonlinear metabolism and disposition of 3,4,4′-trichlorocarbanilide in the rat. Toxicol Appl Pharmacol 46:323-337.
-
(1978)
Toxicol Appl Pharmacol
, vol.46
, pp. 323-337
-
-
Hiles, R.A.1
Birch, C.G.2
-
17
-
-
0018237357
-
The metabolism and disposition of 3,4,4′-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (M. mulatta)
-
Hiles RA, Caudill D, Birch CG, and Eichhold T (1978) The metabolism and disposition of 3,4,4′-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (M. mulatta). Toxicol Appl Pharmacol 46:593-608.
-
(1978)
Toxicol Appl Pharmacol
, vol.46
, pp. 593-608
-
-
Hiles, R.A.1
Caudill, D.2
Birch, C.G.3
Eichhold, T.4
-
18
-
-
70349636047
-
Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases
-
Imig JD and Hammock BD (2009) Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat Rev Drug Discov 8:794-805.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 794-805
-
-
Imig, J.D.1
Hammock, B.D.2
-
19
-
-
0017573761
-
The metabolism and toxicity of halogenated carbanilides. Biliary metabolites of 3,4,4′-trichlorocarbanilide and 3-trifluoromethyl-4, 4′-dichlorocarbanilide in the rat
-
Jeffcoat AR, Handy RW, Francis MT, Willis S, Wall ME, Birch CG, and Hiles RA (1977) The metabolism and toxicity of halogenated carbanilides. Biliary metabolites of 3,4,4′-trichlorocarbanilide and 3-trifluoromethyl-4, 4′-dichlorocarbanilide in the rat. Drug Metab Dispos 5:157-166.
-
(1977)
Drug Metab Dispos
, vol.5
, pp. 157-166
-
-
Jeffcoat, A.R.1
Handy, R.W.2
Francis, M.T.3
Willis, S.4
Wall, M.E.5
Birch, C.G.6
Hiles, R.A.7
-
20
-
-
34547165961
-
Mimicry of phase I drug metabolism - Novel methods for metabolite characterization and synthesis
-
Johansson T, Weidolf L, and Jurva U (2007) Mimicry of phase I drug metabolism - novel methods for metabolite characterization and synthesis. Rapid Commun Mass Spectrom 21:2323-2331.
-
(2007)
Rapid Commun Mass Spectrom
, vol.21
, pp. 2323-2331
-
-
Johansson, T.1
Weidolf, L.2
Jurva, U.3
-
21
-
-
0035996573
-
On the diversity of oxidative bioactivation reactions on nitrogen-containing xenobiotics
-
Kalgutkar AS, Dalvie DK, O'Donnell JP, Taylor TJ, and Sahakian DC (2002) On the diversity of oxidative bioactivation reactions on nitrogen-containing xenobiotics. Curr Drug Metab 3:379-424.
-
(2002)
Curr Drug Metab
, vol.3
, pp. 379-424
-
-
Kalgutkar, A.S.1
Dalvie, D.K.2
O'Donnell, J.P.3
Taylor, T.J.4
Sahakian, D.C.5
-
22
-
-
0031777752
-
Occurrence of the NIH shift upon the cytochrome P450-catalyzed in vivo and in vitro aromatic ring hydroxylation of fluorobenzenes
-
Koerts J, Soffers AE, Vervoort J, De Jager A, and Rietjens IM (1998) Occurrence of the NIH shift upon the cytochrome P450-catalyzed in vivo and in vitro aromatic ring hydroxylation of fluorobenzenes. Chem Res Toxicol 11:503-512.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 503-512
-
-
Koerts, J.1
Soffers, A.E.2
Vervoort, J.3
De Jager, A.4
Rietjens, I.M.5
-
23
-
-
84890020009
-
Boron-doped diamond: A compact review on a new, versatile electrode material
-
Kraft A (2007) Boron-doped diamond: a compact review on a new, versatile electrode material. Int J Electrochem Sci 2:355-385.
-
(2007)
Int J Electrochem Sci
, vol.2
, pp. 355-385
-
-
Kraft, A.1
-
24
-
-
0011623520
-
Liver microsomes: A convenient tool for metabolism
-
(Boobis AR, Kremers P, Pelkonen O, and Pithan K eds) Office for Official Publications of the European Communities, Luxembourg
-
Kremers P (1999) Liver microsomes: a convenient tool for metabolism, in European Symposium on the Prediction of Drug Metabolism in Man: Progress and Problems (Boobis AR, Kremers P, Pelkonen O, and Pithan K eds) pp 38-52, Office for Official Publications of the European Communities, Luxembourg.
-
(1999)
European Symposium on the Prediction of Drug Metabolism in Man: Progress and Problems
, pp. 38-52
-
-
Kremers, P.1
-
25
-
-
67349235583
-
Electrochemical degradation of chlorobenzene on boron-doped diamond and platinum electrodes
-
Liu L, Zhao G, Wu M, Lei Y, and Geng R (2009) Electrochemical degradation of chlorobenzene on boron-doped diamond and platinum electrodes. J Hazard Mater 168:179-186.
-
(2009)
J Hazard Mater
, vol.168
, pp. 179-186
-
-
Liu, L.1
Zhao, G.2
Wu, M.3
Lei, Y.4
Geng, R.5
-
26
-
-
58149134070
-
Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry
-
Lohmann W, Hayen H, and Karst U (2008) Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry. Anal Chem 80:9714-9719.
-
(2008)
Anal Chem
, vol.80
, pp. 9714-9719
-
-
Lohmann, W.1
Hayen, H.2
Karst, U.3
-
27
-
-
33751182073
-
Simulation of the detoxification of paracetamol using on-line electrochemistry/liquid chromatography/mass spectrometry
-
Lohmann W and Karst U (2006) Simulation of the detoxification of paracetamol using on-line electrochemistry/liquid chromatography/mass spectrometry. Anal Bioanal Chem 386:1701-1708.
-
(2006)
Anal Bioanal Chem
, vol.386
, pp. 1701-1708
-
-
Lohmann, W.1
Karst, U.2
-
28
-
-
34548577031
-
Generation and identification of reactive metabolites by electrochemistry and immobilized enzymes coupled on-line to liquid chromatography/mass spectrometry
-
Lohmann W and Karst U (2007) Generation and identification of reactive metabolites by electrochemistry and immobilized enzymes coupled on-line to liquid chromatography/mass spectrometry. Anal Chem 79:6831-6839.
-
(2007)
Anal Chem
, vol.79
, pp. 6831-6839
-
-
Lohmann, W.1
Karst, U.2
-
29
-
-
42449137466
-
Biomimetic modeling of oxidative drug metabolism: Strategies, advantages and limitations
-
Lohmann W and Karst U (2008) Biomimetic modeling of oxidative drug metabolism: strategies, advantages and limitations. Anal Bioanal Chem 391:79-96.
-
(2008)
Anal Bioanal Chem
, vol.391
, pp. 79-96
-
-
Lohmann, W.1
Karst, U.2
-
30
-
-
67449133537
-
Electrochemistry meets enzymes: Instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene
-
Lohmann W and Karst U (2009) Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene. Anal Bioanal Chem 394:1341-1348.
-
(2009)
Anal Bioanal Chem
, vol.394
, pp. 1341-1348
-
-
Lohmann, W.1
Karst, U.2
-
31
-
-
34250731278
-
Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: Correlation to in vitro drug metabolism
-
Madsen KG, Olsen J, Skonberg C, Hansen SH, and Jurva U (2007) Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism. Chem Res Toxicol 20:821-831.
-
(2007)
Chem Res Toxicol
, vol.20
, pp. 821-831
-
-
Madsen, K.G.1
Olsen, J.2
Skonberg, C.3
Hansen, S.H.4
Jurva, U.5
-
32
-
-
75349100795
-
Toxicology in the fast lane: Application of high-throughput bioassays to detect modulation of key enzymes and receptors
-
Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, and Hammock BD (2009) Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect 117:1867-1872.
-
(2009)
Environ Health Perspect
, vol.117
, pp. 1867-1872
-
-
Morisseau, C.1
Merzlikin, O.2
Lin, A.3
He, G.4
Feng, W.5
Padilla, I.6
Denison, M.S.7
Pessah, I.N.8
Hammock, B.D.9
-
33
-
-
33845386728
-
Detection of triclocarban and two co-contaminating chlorocarbanilides in US aquatic environments using isotope dilution liquid chromatography tandem mass spectrometry
-
Sapkota A, Heidler J, and Halden RU (2007) Detection of triclocarban and two co-contaminating chlorocarbanilides in US aquatic environments using isotope dilution liquid chromatography tandem mass spectrometry. Environ Res 103:21-29.
-
(2007)
Environ Res
, vol.103
, pp. 21-29
-
-
Sapkota, A.1
Heidler, J.2
Halden, R.U.3
-
34
-
-
0016442566
-
Percutaneous penetration and disposition of triclocarban in man: Body showering
-
Scharpf LG Jr, Hill ID, and Maibach HI (1975) Percutaneous penetration and disposition of triclocarban in man: body showering. Arch Environ Health 30:7-14.
-
(1975)
Arch Environ Health
, vol.30
, pp. 7-14
-
-
Scharpf Jr., L.G.1
Hill, I.D.2
Maibach, H.I.3
-
35
-
-
0021686434
-
The hydroxylation, dechlorination, and glucuronidation of 4,4′-dichlorobiphenyl (4-DCB) by human hepatic microsomes
-
Schnellmann RG, Volp RF, Putnam CW, and Sipes IG (1984) The hydroxylation, dechlorination, and glucuronidation of 4,4′- dichlorobiphenyl (4-DCB) by human hepatic microsomes. Biochem Pharmacol 33:3503-3509.
-
(1984)
Biochem Pharmacol
, vol.33
, pp. 3503-3509
-
-
Schnellmann, R.G.1
Volp, R.F.2
Putnam, C.W.3
Sipes, I.G.4
-
36
-
-
77952552647
-
-
U.S. Environmental Protection Agency EPA-822-R-08-014. U.S. Environmental Protection Agency, Washington, DC
-
U.S. Environmental Protection Agency (2009) Targeted National Sewage Sludge Survey: overview report. EPA-822-R-08-014. U.S. Environmental Protection Agency, Washington, DC.
-
(2009)
Targeted National Sewage Sludge Survey: Overview Report
-
-
-
37
-
-
21244505432
-
Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry
-
van Leeuwen SM, Blankert B, Kauffmann JM, and Karst U (2005) Prediction of clozapine metabolism by on-line electrochemistry/liquid chromatography/mass spectrometry. Anal Bioanal Chem 382:742-750.
-
(2005)
Anal Bioanal Chem
, vol.382
, pp. 742-750
-
-
Van Leeuwen, S.M.1
Blankert, B.2
Kauffmann, J.M.3
Karst, U.4
-
38
-
-
0642367328
-
HQSAR and CoMFA approaches in predicting reactivity of halogenated compounds with hydroxyl radicals
-
Vrtacnik M and Voda K (2003) HQSAR and CoMFA approaches in predicting reactivity of halogenated compounds with hydroxyl radicals. Chemosphere 52:1689-1699.
-
(2003)
Chemosphere
, vol.52
, pp. 1689-1699
-
-
Vrtacnik, M.1
Voda, K.2
-
40
-
-
0018095163
-
Identification of the metabolites of trichlorocarbanilide in the rat
-
Warren JT, Allen R, and Carter DE (1978) Identification of the metabolites of trichlorocarbanilide in the rat. Drug Metab Dispos 6:38-44.
-
(1978)
Drug Metab Dispos
, vol.6
, pp. 38-44
-
-
Warren, J.T.1
Allen, R.2
Carter, D.E.3
-
41
-
-
13844319935
-
Drug bioactivation, covalent binding to target proteins and toxicity relevance
-
Zhou S, Chan E, Duan W, Huang M, and Chen YZ (2005) Drug bioactivation, covalent binding to target proteins and toxicity relevance. Drug Metab Rev 37:41-213.
-
(2005)
Drug Metab Rev
, vol.37
, pp. 41-213
-
-
Zhou, S.1
Chan, E.2
Duan, W.3
Huang, M.4
Chen, Y.Z.5
|