Electrochemistry-on-chip for on-line conversions in drug metabolism studies

Biosensors and Bioelectronics

Volumn 26, Issue 4, 2010, Pages 1521-1527

  Odijk, M ^a   Baumann, A ^b   Olthuis, W ^a   van den Berg, A ^a   Karst, U ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Drug metabolism; Electrochemistry; High turnover; IrOx; Lab in a Briefcase; Lab on chip; Procainamide

Indexed keywords

DRUG METABOLISMS; HIGH-TURNOVER; IROX; LAB-IN-A-BRIEFCASE; LAB-ON-CHIP; PROCAINAMIDE;

CELLS; ELECTROCHEMICAL CELLS; ELECTROCHEMISTRY; ELECTROLYSIS; ELECTROLYTIC ANALYSIS; ELECTROLYTIC CELLS; IRIDIUM; IRIDIUM COMPOUNDS; LABORATORIES; LIVER; METABOLISM; PLATINUM;

ELECTROCHEMICAL ELECTRODES;

CYTOCHROME P450; IRIDIUM COMPLEX; IRIDIUM OXIDE; PLATINUM; PROCAINAMIDE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG STRUCTURE; ELECTROCHEMISTRY; ENZYME MECHANISM; EXPERIMENTAL DESIGN; HUMAN; HUMAN CELL; INCUBATION TIME; LAB ON A CHIP; LIVER MICROSOME; MALE; NONHUMAN; ONLINE SYSTEM; PH ELECTRODE; PROTEIN FAMILY; RAT; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; BIOSENSING TECHNIQUES; ELECTROCHEMICAL TECHNIQUES; ELECTRODES; EQUIPMENT DESIGN; HUMANS; HYDROGEN-ION CONCENTRATION; IRIDIUM; LAB-ON-A-CHIP DEVICES; MICROSOMES, LIVER; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; PLATINUM; PROCAINAMIDE; RATS;

RATTUS;

EID: 78649732401     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2010.07.102     Document Type: Article

References (26)

1. Bard A., Faulkner L. Electrochemical Methods 2001, Wiley, p. 52. 2nd ed.
2. Baumann A., Lohmann W., Schubert B., Oberacher H., Karst U. J. Chromatogr. A 2009, 1216(15):3192-3198.
3. Baumann A., Karst U. Expert Opin. Drug Metab. Toxicol. 2010, 6(6):715-731.
4. Brandon E., Raap C., Meijerman I., Beijnen J., Schellens J. Toxicol. Appl. Pharmacol. 2003, 189:233-246.
5. Carroll S., Baldwin R. Anal. Chem. 2010, 82:878-885.
6. Guengerich F. Drug Metabolism in Drug Design and Development 2007, Wiley & Sons Inc., pp. 15-31.
7. Ha H., Follath F. Curr. Drug Metab. 2004, 5:543-571.
8. Ives D., Janz G. Reference Electrodes 1961, Academic Press.
9. Iyer R., Zhang D. Drug Metabolism in Drug Design and Development 2007, Wiley & Sons Inc., p. 265.
10. Johansson T., Weidolf L., Jurva U. Rapid Commun. Mass Spectrom. 2007, 21:2323-2331.
11. Li C., Wu P., Jung W., Ahn C., Shutter L., Narayan R. IEEE Transducers Conf. 2009, T4B.
12. Lohmann W., Karst U. Anal. Chem. 2007, 79:6831-6839.
13. Lohmann W., Karst U. Anal. Bioanal. Chem. 2008, 391:79-96.
14. Lohmann W., Hayen H., Karst U. Anal. Chem. 2009, 80:714-9719.
15. Marzouk S., Ufer S., Buck R., Johnson T., Dunlap L., Cascio W. Anal. Chem. 1998, 70:5054-5061.
16. Midgley D. Talanta 1990, 37(8):767-781.
17. Nissila, T., Sainiemi, L., Karikko, M., Kemell, M., Ritala, M., Franssila, S., 2009. Microtas Conf., W72F.
18. Odijk M., Baumann A., Lohmann W., van den Brink F., Olthuis W., Karst U. Lab Chip 2009, 9:1687-1693.
19. Olthuis W., Robben M., Bergveld P., Bos M., van der Linden W. Sens. Actuators B 1990, 4:247-256.
20. Park B., Kitteringham N., Maggs J., Pirmohamed M., Williams D. Annu. Rev. Pharmacol. Toxicol. 2000, 45:177-202.
21. Permentier H., Bruins A., Bischoff R. Mini-Rev. Med. Chem. 2008, 8:46-56.
22. Schabmueller C., Loppow D., Piechotta G., Schütze B., Albers J., Hintsche R. Biosens. Bioelectron. 2006, 21(9):1770-1776.
23. van Leeuwen S., Blankert B., Kaufmann J.M., Karst U. Anal. Bioanal. Chem. 2005, 382:742-750.
24. Wang M., Yao S., Madou M. Sens. Actuators B 2002, 81:313-315.
25. Yang H., Kang S., Choi C., Kim H., Shin D., Kim Y. Lab Chip 2004, 4:42-46.
26. Yao S., Wang M., Madou M. J. Electrochem. Soc. 2001, 148:H29-H36.