메뉴 건너뛰기




Volumn 52, Issue 3, 2010, Pages 194-202

Spatial and temporal expression of CCR3 and the common beta chain of the IL-3, IL-5 and GM-CSF receptor in the nasal epithelium and lymphoid tissues in a rat model of allergic rhinitis

Author keywords

Allergic rhinitis; Beta chain; CCR3; Inflammation; Nasal mucosa

Indexed keywords

ALLERGEN; CHEMOKINE RECEPTOR CCR3; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 3; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 5; MESSENGER RNA; MUCIN 5AC; TUMOR NECROSIS FACTOR ALPHA; CCR3 PROTEIN, RAT; PRIMER DNA;

EID: 79953302461     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.07.005     Document Type: Article
Times cited : (10)

References (57)
  • 1
    • 0042672665 scopus 로고    scopus 로고
    • Links between rhinitis and asthma
    • Bousquet J., Vignola A.M., Demoly P. Links between rhinitis and asthma. Allergy 2003, 58:691-706.
    • (2003) Allergy , vol.58 , pp. 691-706
    • Bousquet, J.1    Vignola, A.M.2    Demoly, P.3
  • 2
    • 35348864254 scopus 로고    scopus 로고
    • Allergic rhinitis and asthma: inflammation in a one-airway condition
    • Jeffery P., Haahtela T. Allergic rhinitis and asthma: inflammation in a one-airway condition. BMC Pulm Med 2006, 6:S5.
    • (2006) BMC Pulm Med , vol.6
    • Jeffery, P.1    Haahtela, T.2
  • 3
    • 7444228630 scopus 로고    scopus 로고
    • Inflammatory mediators in allergic rhinitis
    • Gelfand E.W. Inflammatory mediators in allergic rhinitis. J Allergy Clin Immunol 2004, 114:S135-S138.
    • (2004) J Allergy Clin Immunol , vol.114
    • Gelfand, E.W.1
  • 4
    • 0032822390 scopus 로고    scopus 로고
    • Allergic rhinobronchitis: the asthma-allergic rhinitis link
    • Simons F. Allergic rhinobronchitis: the asthma-allergic rhinitis link. J Allergy Clin Immunol 1999, 104:534-540.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 534-540
    • Simons, F.1
  • 5
    • 0037841802 scopus 로고    scopus 로고
    • Rhinitis and asthma: evidence for respiratory system integration
    • Togias A. Rhinitis and asthma: evidence for respiratory system integration. J Allergy Clin Immunol 2003, 111:1171-1183.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1171-1183
    • Togias, A.1
  • 7
    • 0032875421 scopus 로고    scopus 로고
    • Perennial rhinitis: an independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey
    • Leynaert B., Bousquet J., Neukirch C., Liard R., Neukirch F. Perennial rhinitis: an independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey. J Allergy Clin Immunol 1999, 104:301-304.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 301-304
    • Leynaert, B.1    Bousquet, J.2    Neukirch, C.3    Liard, R.4    Neukirch, F.5
  • 9
    • 3042538102 scopus 로고    scopus 로고
    • Effect of glucocorticosteroids on tumour necrosis factor-α-induced intercellular adhesion molecule-1 expression in cultured primary human nasal epithelial cells
    • Shirasaki H., Watanabe K., Kanaizumi E., Sato J., Konno N., Narita S., et al. Effect of glucocorticosteroids on tumour necrosis factor-α-induced intercellular adhesion molecule-1 expression in cultured primary human nasal epithelial cells. Clin Exp Allergy 2004, 34:945-951.
    • (2004) Clin Exp Allergy , vol.34 , pp. 945-951
    • Shirasaki, H.1    Watanabe, K.2    Kanaizumi, E.3    Sato, J.4    Konno, N.5    Narita, S.6
  • 13
    • 0025008579 scopus 로고
    • The eosinophil and bronchial asthma: current understanding
    • Gleich G.J. The eosinophil and bronchial asthma: current understanding. J Allergy Clin Immunol 1990, 85:422-436.
    • (1990) J Allergy Clin Immunol , vol.85 , pp. 422-436
    • Gleich, G.J.1
  • 16
    • 0029060674 scopus 로고
    • Cloning and functional expression of a human eosinophil CC chemokine receptor
    • Combadiere C., Ahuja S.K., Murphy P.M. Cloning and functional expression of a human eosinophil CC chemokine receptor. J Biol Chem 1995, 270:16491-16494.
    • (1995) J Biol Chem , vol.270 , pp. 16491-16494
    • Combadiere, C.1    Ahuja, S.K.2    Murphy, P.M.3
  • 17
    • 0027715955 scopus 로고
    • The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo
    • Griffiths-Johnson D., Collins P., Rossi A., Jose P., Williams T. The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo. Biochem Biophys Res Commun 1993, 197:1167-1172.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1167-1172
    • Griffiths-Johnson, D.1    Collins, P.2    Rossi, A.3    Jose, P.4    Williams, T.5
  • 18
    • 0028140133 scopus 로고
    • Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. Tokyo Joshi-Idai Asthma Research Group
    • Jose P.J., Griffiths-Johnson D.A., Collins P.D., Walsh D.T., Moqbel R., Totty N.F., et al. Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. Tokyo Joshi-Idai Asthma Research Group. J Exp Med 1994, 179:881-887.
    • (1994) J Exp Med , vol.179 , pp. 881-887
    • Jose, P.J.1    Griffiths-Johnson, D.A.2    Collins, P.D.3    Walsh, D.T.4    Moqbel, R.5    Totty, N.F.6
  • 19
    • 0242467200 scopus 로고    scopus 로고
    • Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity
    • Yang M., Hogan S.P., Mahalingam S., Pope S.M., Zimmermann N., Fulkerson P., et al. Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. J Allergy Clin Immunol 2003, 112:935-943.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 935-943
    • Yang, M.1    Hogan, S.P.2    Mahalingam, S.3    Pope, S.M.4    Zimmermann, N.5    Fulkerson, P.6
  • 21
    • 0025861759 scopus 로고
    • Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors
    • Kitamura T., Sato N., Arai K., Miyajima A. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 1991, 66:1165-1174.
    • (1991) Cell , vol.66 , pp. 1165-1174
    • Kitamura, T.1    Sato, N.2    Arai, K.3    Miyajima, A.4
  • 22
    • 0034702534 scopus 로고    scopus 로고
    • Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study
    • Tamaoki J., Kondo M., Sakai N., Aoshiba K., Tagaya E., Nakata J., et al. Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Lancet 2000, 356:273-278.
    • (2000) Lancet , vol.356 , pp. 273-278
    • Tamaoki, J.1    Kondo, M.2    Sakai, N.3    Aoshiba, K.4    Tagaya, E.5    Nakata, J.6
  • 23
    • 33746358214 scopus 로고    scopus 로고
    • Cytokines or their antagonists for the treatment of asthma
    • O'Byrne P.M. Cytokines or their antagonists for the treatment of asthma. Chest 2006, 130:244-250.
    • (2006) Chest , vol.130 , pp. 244-250
    • O'Byrne, P.M.1
  • 26
    • 33746584330 scopus 로고    scopus 로고
    • CCR3, CCR5, CCR8 and CXCR3 expression in memory T helper cells from allergic rhinitis patients, asymptomatically sensitized and healthy individuals
    • Holse M., Assing K., Poulsen L.K. CCR3, CCR5, CCR8 and CXCR3 expression in memory T helper cells from allergic rhinitis patients, asymptomatically sensitized and healthy individuals. Clin Mol Allergy 2006, 4:6-12.
    • (2006) Clin Mol Allergy , vol.4 , pp. 6-12
    • Holse, M.1    Assing, K.2    Poulsen, L.K.3
  • 28
    • 33344458849 scopus 로고    scopus 로고
    • Increased expression of RANTES, CCR3 and CCR5 in the lesional skin of patients with atopic eczema
    • Kato Y., Pawankar R., Kimura Y., Kawana S. Increased expression of RANTES, CCR3 and CCR5 in the lesional skin of patients with atopic eczema. Int Arch Allergy Immunol 2006, 139:245-257.
    • (2006) Int Arch Allergy Immunol , vol.139 , pp. 245-257
    • Kato, Y.1    Pawankar, R.2    Kimura, Y.3    Kawana, S.4
  • 29
    • 0041734942 scopus 로고    scopus 로고
    • Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge
    • Liu L., Jarjour N., Busse W., Kelly E. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge. J Allergy Clin Immunol 2003, 112:556-562.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 556-562
    • Liu, L.1    Jarjour, N.2    Busse, W.3    Kelly, E.4
  • 30
    • 33744994158 scopus 로고    scopus 로고
    • Aberrant expression of CC and CXC chemokines and their receptors in patients with asthma
    • Lun S., Wong C., Ko F., Ip W., Hui D., Lam C. Aberrant expression of CC and CXC chemokines and their receptors in patients with asthma. J Clin Immunol 2006, 26:145-152.
    • (2006) J Clin Immunol , vol.26 , pp. 145-152
    • Lun, S.1    Wong, C.2    Ko, F.3    Ip, W.4    Hui, D.5    Lam, C.6
  • 31
    • 0032884733 scopus 로고    scopus 로고
    • CCR3 mRNA expression in bronchial epithelial cells and various cells in allergic inflammation
    • Oyamada H., Kamada Y., Kuwasaki T., Yamada Y., Kobayashi Y., Cui C., et al. CCR3 mRNA expression in bronchial epithelial cells and various cells in allergic inflammation. Int Arch Allergy Immunol 1999, 120:45-47.
    • (1999) Int Arch Allergy Immunol , vol.120 , pp. 45-47
    • Oyamada, H.1    Kamada, Y.2    Kuwasaki, T.3    Yamada, Y.4    Kobayashi, Y.5    Cui, C.6
  • 32
  • 33
    • 8644254156 scopus 로고    scopus 로고
    • Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases
    • Elsner J., Escher S.E., Forssmann U. Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases. Allergy 2004, 59:1243-1258.
    • (2004) Allergy , vol.59 , pp. 1243-1258
    • Elsner, J.1    Escher, S.E.2    Forssmann, U.3
  • 34
    • 33751094071 scopus 로고    scopus 로고
    • Effects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in rats
    • Fortin M., Ferrari N., Higgins M.-E., Seguin S., Allam M., Allakhverdi Z., et al. Effects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in rats. Oligonucleotides 2006, 16:203-212.
    • (2006) Oligonucleotides , vol.16 , pp. 203-212
    • Fortin, M.1    Ferrari, N.2    Higgins, M.-E.3    Seguin, S.4    Allam, M.5    Allakhverdi, Z.6
  • 35
    • 0036314229 scopus 로고    scopus 로고
    • CCR3-blocking antibody inhibits allergen-induced eosinophil recruitment in human skin xenografts from allergic patients
    • Senechal S., Fahy O., Gentina T., Vorng H., Capron M., Walls A., et al. CCR3-blocking antibody inhibits allergen-induced eosinophil recruitment in human skin xenografts from allergic patients. Lab Invest 2002, 82:929-939.
    • (2002) Lab Invest , vol.82 , pp. 929-939
    • Senechal, S.1    Fahy, O.2    Gentina, T.3    Vorng, H.4    Capron, M.5    Walls, A.6
  • 37
    • 33745268232 scopus 로고    scopus 로고
    • Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation
    • Das A.M., Vaddi K.G., Solomon K.A., Krauthauser C., Jiang X., McIntyre K.W., et al. Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation. J Pharmacol Exp Ther 2006, 318:411-417.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 411-417
    • Das, A.M.1    Vaddi, K.G.2    Solomon, K.A.3    Krauthauser, C.4    Jiang, X.5    McIntyre, K.W.6
  • 38
    • 0036528907 scopus 로고    scopus 로고
    • Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma
    • Allakhverdi Z., Allam M., Renzi P.M. Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma. Am J Respir Crit Care Med 2002, 165:1015-1021.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1015-1021
    • Allakhverdi, Z.1    Allam, M.2    Renzi, P.M.3
  • 39
    • 42949132127 scopus 로고    scopus 로고
    • Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses
    • Gauvreau G.M., Boulet L.P., Cockcroft D.W., Baatjes A., Cote J., Deschesnes F., et al. Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. Am J Respir Crit Care Med 2008, 177:952-958.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 952-958
    • Gauvreau, G.M.1    Boulet, L.P.2    Cockcroft, D.W.3    Baatjes, A.4    Cote, J.5    Deschesnes, F.6
  • 40
    • 34248327274 scopus 로고    scopus 로고
    • Rodent models of allergic rhinitis: relevance to human pathophysiology
    • Wagner J.G., Harkema J.R. Rodent models of allergic rhinitis: relevance to human pathophysiology. Curr Allergy Asthma Rep 2007, 7:134-140.
    • (2007) Curr Allergy Asthma Rep , vol.7 , pp. 134-140
    • Wagner, J.G.1    Harkema, J.R.2
  • 41
    • 0023223047 scopus 로고
    • Effects of an ambient level of ozone on primate nasal epithelial mucosubstances. Quantitative histochemistry
    • Harkema J., Plopper C., Hyde D., St George J., Dungworth D. Effects of an ambient level of ozone on primate nasal epithelial mucosubstances. Quantitative histochemistry. Am J Pathol 1987, 127:90-96.
    • (1987) Am J Pathol , vol.127 , pp. 90-96
    • Harkema, J.1    Plopper, C.2    Hyde, D.3    St George, J.4    Dungworth, D.5
  • 42
    • 0036307446 scopus 로고    scopus 로고
    • Enhancement of nasal inflammatory and epithelial responses after ozone and allergen coexposure in brown Norway rats
    • Wagner J.G., Hotchkiss J.A., Harkema J.R. Enhancement of nasal inflammatory and epithelial responses after ozone and allergen coexposure in brown Norway rats. Toxicol Sci 2002, 67:284-294.
    • (2002) Toxicol Sci , vol.67 , pp. 284-294
    • Wagner, J.G.1    Hotchkiss, J.A.2    Harkema, J.R.3
  • 44
    • 0036846875 scopus 로고    scopus 로고
    • Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T Cells and interleukin-9
    • Whittaker L., Niu N., Temann U.A., Stoddard A., Flavell R.A., Ray A., et al. Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T Cells and interleukin-9. Am J Respir Cell Mol Biol 2002, 27:593-602.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 593-602
    • Whittaker, L.1    Niu, N.2    Temann, U.A.3    Stoddard, A.4    Flavell, R.A.5    Ray, A.6
  • 45
    • 33646777094 scopus 로고    scopus 로고
    • The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium
    • Harkema J., Carey S., Wagner J. The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium. Toxicol Pathol 2006, 34:252-269.
    • (2006) Toxicol Pathol , vol.34 , pp. 252-269
    • Harkema, J.1    Carey, S.2    Wagner, J.3
  • 46
    • 2942711806 scopus 로고    scopus 로고
    • Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice
    • Farraj A.K., Harkema J.R., Kaminski N.E. Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice. Toxicol Sci 2004, 79:315-325.
    • (2004) Toxicol Sci , vol.79 , pp. 315-325
    • Farraj, A.K.1    Harkema, J.R.2    Kaminski, N.E.3
  • 47
    • 0042591315 scopus 로고    scopus 로고
    • Ozone exposure enhances endotoxin-induced mucous cell metaplasia in rat pulmonary airways
    • Wagner J.G., Van Dyken S.J., Wierenga J.R., Hotchkiss J.A., Harkema J.R. Ozone exposure enhances endotoxin-induced mucous cell metaplasia in rat pulmonary airways. Toxicol Sci 2003, 74:437-446.
    • (2003) Toxicol Sci , vol.74 , pp. 437-446
    • Wagner, J.G.1    Van Dyken, S.J.2    Wierenga, J.R.3    Hotchkiss, J.A.4    Harkema, J.R.5
  • 48
    • 0030638533 scopus 로고    scopus 로고
    • Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3
    • Humbert M., Ying S., Corrigan C., Menz G., Barkans J., Pfister R., et al. Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3. Am J Respir Cell Mol Biol 1997, 16:1-8.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 1-8
    • Humbert, M.1    Ying, S.2    Corrigan, C.3    Menz, G.4    Barkans, J.5    Pfister, R.6
  • 49
    • 0033485409 scopus 로고    scopus 로고
    • Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and CC chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics
    • Ying S., Meng Q., Zeibecoglou K., Robinson D.S., Macfarlane A., Humbert M., et al. Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and CC chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1999, 163:6321-6329.
    • (1999) J Immunol , vol.163 , pp. 6321-6329
    • Ying, S.1    Meng, Q.2    Zeibecoglou, K.3    Robinson, D.S.4    Macfarlane, A.5    Humbert, M.6
  • 50
    • 35548959281 scopus 로고    scopus 로고
    • Complementary DNA microarray analysis of chemokines and their receptors in allergic rhinitis
    • Zhang R.X., Yu S.Q., Jiang J.Z., Liu G.J. Complementary DNA microarray analysis of chemokines and their receptors in allergic rhinitis. J Investig Allergol Clin Immunol 2007, 17:329-336.
    • (2007) J Investig Allergol Clin Immunol , vol.17 , pp. 329-336
    • Zhang, R.X.1    Yu, S.Q.2    Jiang, J.Z.3    Liu, G.J.4
  • 51
    • 0026603643 scopus 로고
    • Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia
    • Durham S.R., Ying S., Varney V.A., Jacobson M.R., Sudderick R.M., Mackay I.S., et al. Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. J Immunol 1992, 148:2390-2394.
    • (1992) J Immunol , vol.148 , pp. 2390-2394
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3    Jacobson, M.R.4    Sudderick, R.M.5    Mackay, I.S.6
  • 52
    • 0028355144 scopus 로고
    • Interleukin-5 gene expression in nasal mucosa and changes in amount of interleukin-5 in nasal lavage fluid after antigen challenge
    • Terada N., Konno A., Fukuda S., Yamashita T., Shirotori K., Okamoto Y., et al. Interleukin-5 gene expression in nasal mucosa and changes in amount of interleukin-5 in nasal lavage fluid after antigen challenge. Acta Otolaryngol 1994, 114:203-208.
    • (1994) Acta Otolaryngol , vol.114 , pp. 203-208
    • Terada, N.1    Konno, A.2    Fukuda, S.3    Yamashita, T.4    Shirotori, K.5    Okamoto, Y.6
  • 53
    • 38949201705 scopus 로고    scopus 로고
    • Immunomodulators for allergic respiratory disorders
    • Casale T.B., Stokes J.R. Immunomodulators for allergic respiratory disorders. J Allergy Clin Immunol 2008, 121:288-296.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 288-296
    • Casale, T.B.1    Stokes, J.R.2
  • 54
    • 0035881031 scopus 로고    scopus 로고
    • The kinetics of allergen-induced eotaxin level in nasal lavage fluid. Its key role in eosinophil recruitment in nasal mucosa
    • Terada N., Hamano N., Kim W.J., Hirai K., Nakajima T., Yamada H., et al. The kinetics of allergen-induced eotaxin level in nasal lavage fluid. Its key role in eosinophil recruitment in nasal mucosa. Am J Respir Crit Care Med 2001, 164:575-579.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 575-579
    • Terada, N.1    Hamano, N.2    Kim, W.J.3    Hirai, K.4    Nakajima, T.5    Yamada, H.6
  • 56
    • 34247178673 scopus 로고    scopus 로고
    • Intranasal antisense therapy: preclinical models with a clinical future?
    • Bitko V., Barik S. Intranasal antisense therapy: preclinical models with a clinical future?. Curr Opin Mol Ther 2007, 9:119-125.
    • (2007) Curr Opin Mol Ther , vol.9 , pp. 119-125
    • Bitko, V.1    Barik, S.2
  • 57
    • 33645382880 scopus 로고    scopus 로고
    • Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo
    • Griesenbach U., Kitson C., Escudero Garcia S., Farley R., Singh C., Somerton L., et al. Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo. Respir Res 2006, 7:26-41.
    • (2006) Respir Res , vol.7 , pp. 26-41
    • Griesenbach, U.1    Kitson, C.2    Escudero Garcia, S.3    Farley, R.4    Singh, C.5    Somerton, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.