-
1
-
-
0031025249
-
-
Nyce JW, Metzger WJ: DNA antisense therapy for asthma in an animal model. Nature (1997) 385(6618):721-725. • The first report of the use of RASONS against asthma in an animal model.
-
Nyce JW, Metzger WJ: DNA antisense therapy for asthma in an animal model. Nature (1997) 385(6618):721-725. • The first report of the use of RASONS against asthma in an animal model.
-
-
-
-
2
-
-
0036528907
-
Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common β chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma
-
Allakhverdi Z, Allam M, Renzi PM: Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common β chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma. Am J Respir Crit Care Med (2002) 165(7):1015-1021.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, Issue.7
, pp. 1015-1021
-
-
Allakhverdi, Z.1
Allam, M.2
Renzi, P.M.3
-
3
-
-
0035061661
-
Absorption, distribution, metabolism, and excretion of a respirable antisense oligonucleotide for asthma
-
Ali S, Leonard SA, Kukoly CA, Metzger WJ, Wooles WR, McGinty JF, Tanaka M, Sandrasagra A, Nyce JW: Absorption, distribution, metabolism, and excretion of a respirable antisense oligonucleotide for asthma. Am J Respir Crit Care Med (2001) 163(4):989-993.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, Issue.4
, pp. 989-993
-
-
Ali, S.1
Leonard, S.A.2
Kukoly, C.A.3
Metzger, W.J.4
Wooles, W.R.5
McGinty, J.F.6
Tanaka, M.7
Sandrasagra, A.8
Nyce, J.W.9
-
4
-
-
14944350956
-
Inhaled p38α mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice
-
Duan W, Chan JH, McKay K, Crosby JR, Choo HH, Leung BP, Karras JG, Wong WS: Inhaled p38α mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. Am J Respir Crit Care Med (2005) 171(6):571-578.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.6
, pp. 571-578
-
-
Duan, W.1
Chan, J.H.2
McKay, K.3
Crosby, J.R.4
Choo, H.H.5
Leung, B.P.6
Karras, J.G.7
Wong, W.S.8
-
5
-
-
0035806279
-
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression
-
Finotto S, De Sanctis GT, Lehr HA, Herz U, Buerke M, Schipp M, Bartsch B, Atreya R, Schmitt E, Galle PR, Renz H et al: Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression. J Exp Med (2001) 193(11):1247-1260.
-
(2001)
J Exp Med
, vol.193
, Issue.11
, pp. 1247-1260
-
-
Finotto, S.1
De Sanctis, G.T.2
Lehr, H.A.3
Herz, U.4
Buerke, M.5
Schipp, M.6
Bartsch, B.7
Atreya, R.8
Schmitt, E.9
Galle, P.R.10
Renz, H.11
-
6
-
-
0032797697
-
CFTR antisense phosphorothioate oligodeoxynucleotides (S-ODNs) induce tracheo-bronchial mucin (TBM) mRNA expression in human airway mucosa
-
Verma M, Baraniuk J, Blass C, Ali M, Yuta A, Biedlningmaier J, Davidson EA: CFTR antisense phosphorothioate oligodeoxynucleotides (S-ODNs) induce tracheo-bronchial mucin (TBM) mRNA expression in human airway mucosa. Glycoconjugate J (1999) 16(1):7-11.
-
(1999)
Glycoconjugate J
, vol.16
, Issue.1
, pp. 7-11
-
-
Verma, M.1
Baraniuk, J.2
Blass, C.3
Ali, M.4
Yuta, A.5
Biedlningmaier, J.6
Davidson, E.A.7
-
7
-
-
24744466699
-
-
Li BJ, Tang Q, Cheng D, Qin C, Xie FY, Wei Q, Xu J, Liu Y, Zheng BJ, Woodle MC, Zhong N et al: Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med (2005) 11(9):944-951. • The first report of using RNAi against SARS-CoV in an animal model.
-
Li BJ, Tang Q, Cheng D, Qin C, Xie FY, Wei Q, Xu J, Liu Y, Zheng BJ, Woodle MC, Zhong N et al: Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med (2005) 11(9):944-951. • The first report of using RNAi against SARS-CoV in an animal model.
-
-
-
-
8
-
-
13444262170
-
-
Bitko V, Musiyenko A, Shulyayeva O, Barik S: Inhibition of respiratory viruses by nasally administered siRNA. Nat Med (2005) 11(1):50-55. • This research formed the basis of the first clinical trial (by Alnylam) of nasal siRNA against RSV.
-
Bitko V, Musiyenko A, Shulyayeva O, Barik S: Inhibition of respiratory viruses by nasally administered siRNA. Nat Med (2005) 11(1):50-55. • This research formed the basis of the first clinical trial (by Alnylam) of nasal siRNA against RSV.
-
-
-
-
9
-
-
2942530436
-
Inhibition of influenza virus production in virus-infected mice by RNA interference
-
Ge Q, Filip L, Bai A, Nguyen T, Eisen HN, Chen J: Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc Natl Acad Sci USA (2004) 101(23):8676-8681.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.23
, pp. 8676-8681
-
-
Ge, Q.1
Filip, L.2
Bai, A.3
Nguyen, T.4
Eisen, H.N.5
Chen, J.6
-
10
-
-
2942620143
-
Protection against lethal influenza virus challenge by RNA interference in vivo
-
Tompkins SM, Lo CY, Tumpey TM, Epstein SL: Protection against lethal influenza virus challenge by RNA interference in vivo. Proc Natl Acad Sci USA (2004) 101(23):8682-8686.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.23
, pp. 8682-8686
-
-
Tompkins, S.M.1
Lo, C.Y.2
Tumpey, T.M.3
Epstein, S.L.4
-
11
-
-
26044469804
-
Silence of the transcripts: RNA interference in medicine
-
Barik S: Silence of the transcripts: RNA interference in medicine. J Mol Med (2005) 83(10):764-773.
-
(2005)
J Mol Med
, vol.83
, Issue.10
, pp. 764-773
-
-
Barik, S.1
-
12
-
-
33750809978
-
Prospects of RNA interference therapy in respiratory viral diseases: Update 2006
-
Barik S, Bitko V: Prospects of RNA interference therapy in respiratory viral diseases: Update 2006. Expert Opin Biol Ther (2006) 6(11):1151-1160.
-
(2006)
Expert Opin Biol Ther
, vol.6
, Issue.11
, pp. 1151-1160
-
-
Barik, S.1
Bitko, V.2
-
13
-
-
1542269161
-
Progress in antisense technology
-
Crooke ST: Progress in antisense technology. Annu Rev Med (2004) 55:61-95.
-
(2004)
Annu Rev Med
, vol.55
, pp. 61-95
-
-
Crooke, S.T.1
-
14
-
-
0035721542
-
Respirable antisense oligonucleotides: A new drug class for respiratory disease
-
Tanaka M, Nyce JW: Respirable antisense oligonucleotides: A new drug class for respiratory disease. Respir Res (2001) 2(1):5-9.
-
(2001)
Respir Res
, vol.2
, Issue.1
, pp. 5-9
-
-
Tanaka, M.1
Nyce, J.W.2
-
15
-
-
0023057552
-
-
Minshull J, Hunt T: The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. Nucleic Acids Res (1986) 14(16):6433-6451. • The first study demonstrating that antisense oligonucleotides appear to act specifically by directing RNase H cleavage and destabilizing their complementary mRNA.
-
Minshull J, Hunt T: The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. Nucleic Acids Res (1986) 14(16):6433-6451. • The first study demonstrating that antisense oligonucleotides appear to act specifically by directing RNase H cleavage and destabilizing their complementary mRNA.
-
-
-
-
16
-
-
0024041180
-
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
-
Walder RY, Walder JA: Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc Natl Acad Sci USA (1988) 85(14):5011-1015.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, Issue.14
, pp. 5011-1015
-
-
Walder, R.Y.1
Walder, J.A.2
-
17
-
-
0025102250
-
Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: Studies of An2 and cyclin in embryogenesis
-
Dagle JM, Walder JA, Weeks DL: Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: Studies of An2 and cyclin in embryogenesis. Nucleic Acids Res (1990) 18(16):4751-4757.
-
(1990)
Nucleic Acids Res
, vol.18
, Issue.16
, pp. 4751-4757
-
-
Dagle, J.M.1
Walder, J.A.2
Weeks, D.L.3
-
18
-
-
0034780950
-
Drug properties of secondgeneration antisense oligonucleotides: How do they measure up to their predecessors?
-
Henry SP, Geary RS, Yu R, Levin AA: Drug properties of secondgeneration antisense oligonucleotides: How do they measure up to their predecessors? Curr Opin Investig Drugs (2001) 2(10):1444-1449.
-
(2001)
Curr Opin Investig Drugs
, vol.2
, Issue.10
, pp. 1444-1449
-
-
Henry, S.P.1
Geary, R.S.2
Yu, R.3
Levin, A.A.4
-
19
-
-
0027168725
-
Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, Kawasaki AM, Cook PD, Freier SM: Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J Biol Chem (1993) 268(19):14514-14522.
-
(1993)
J Biol Chem
, vol.268
, Issue.19
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
20
-
-
0032473890
-
LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition
-
Koshkin AA, Singh SK, Nielsen P, Rajwanshi VK, Kumar R, Melgaard M, Olsen CE, Wengel J: LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition. Tetrahedron (1998) 54(14):3607-3630.
-
(1998)
Tetrahedron
, vol.54
, Issue.14
, pp. 3607-3630
-
-
Koshkin, A.A.1
Singh, S.K.2
Nielsen, P.3
Rajwanshi, V.K.4
Kumar, R.5
Melgaard, M.6
Olsen, C.E.7
Wengel, J.8
-
21
-
-
0035113736
-
Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA
-
Braasch DA, Corey DR: Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA. Chem Biol (2001) 8(1):1-7.
-
(2001)
Chem Biol
, vol.8
, Issue.1
, pp. 1-7
-
-
Braasch, D.A.1
Corey, D.R.2
-
22
-
-
0035048016
-
Application of PNA and LNA oligomers to chemotherapy
-
Elayadi AN, Corey DR: Application of PNA and LNA oligomers to chemotherapy. Curr Opin Investig Drugs (2001) 2(4):558-561.
-
(2001)
Curr Opin Investig Drugs
, vol.2
, Issue.4
, pp. 558-561
-
-
Elayadi, A.N.1
Corey, D.R.2
-
23
-
-
0033607615
-
Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation
-
Dias N, Dheur S, Nielsen PE, Gryaznov S, Van Aerschot A, Herdewijn P, Helene C, Saison-Behmoaras TE: Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation. J Mol Biol (1991) 294(2):403-416.
-
(1991)
J Mol Biol
, vol.294
, Issue.2
, pp. 403-416
-
-
Dias, N.1
Dheur, S.2
Nielsen, P.E.3
Gryaznov, S.4
Van Aerschot, A.5
Herdewijn, P.6
Helene, C.7
Saison-Behmoaras, T.E.8
-
24
-
-
0032724911
-
Novel mechanisms for antisense-mediated regulation of gene expression
-
Baker BF, Monia BP: Novel mechanisms for antisense-mediated regulation of gene expression. Biochim Biophys Acta (1999) 1489(1):3-18.
-
(1999)
Biochim Biophys Acta
, vol.1489
, Issue.1
, pp. 3-18
-
-
Baker, B.F.1
Monia, B.P.2
-
25
-
-
0030862707
-
Morpholino antisense oligomers: Design, preparation, and properties
-
Summerton J, Weller D: Morpholino antisense oligomers: Design, preparation, and properties. Antisense Nucleic Acid Drug Dev (1997) 7(3):187-195.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, Issue.3
, pp. 187-195
-
-
Summerton, J.1
Weller, D.2
-
26
-
-
0028983405
-
Oligonucleotide N3′→P5′ phosphoramidates
-
Gryaznov SM, Lloyd DH, Chen JK, Schultz RG, DeDionisio LA, Ratmeyer L, Wilson WD: Oligonucleotide N3′→P5′ phosphoramidates. Proc Nat Acad Sci USA (1995) 92(13):5798-5802.
-
(1995)
Proc Nat Acad Sci USA
, vol.92
, Issue.13
, pp. 5798-5802
-
-
Gryaznov, S.M.1
Lloyd, D.H.2
Chen, J.K.3
Schultz, R.G.4
DeDionisio, L.A.5
Ratmeyer, L.6
Wilson, W.D.7
-
27
-
-
0029156023
-
Synthesis of oligodeoxyribonucleotide N3′→P5′ phosphoramidates
-
Chen JK, Schultz RG, Lloyd DH, Gryaznov SM: Synthesis of oligodeoxyribonucleotide N3′→P5′ phosphoramidates. Nucleic Acids Res (1995) 23(14):2661-2668.
-
(1995)
Nucleic Acids Res
, vol.23
, Issue.14
, pp. 2661-2668
-
-
Chen, J.K.1
Schultz, R.G.2
Lloyd, D.H.3
Gryaznov, S.M.4
-
28
-
-
0029664865
-
Oligonucleotide N3′→ P5′ phosphoramidates as antisense agents
-
Gryaznov S, Skorski T, Cucco C, Nieborowska-Skorska M, Chiu CY, Lloyd D, Chen JK, Koziolkiewicz M, Calabretta B: Oligonucleotide N3′→ P5′ phosphoramidates as antisense agents. Nucleic Acids Res (1996) 24(8):1508-1514.
-
(1996)
Nucleic Acids Res
, vol.24
, Issue.8
, pp. 1508-1514
-
-
Gryaznov, S.1
Skorski, T.2
Cucco, C.3
Nieborowska-Skorska, M.4
Chiu, C.Y.5
Lloyd, D.6
Chen, J.K.7
Koziolkiewicz, M.8
Calabretta, B.9
-
29
-
-
0030937825
-
Antileukemia effect of c-myc N3′→P5′ phosphoramidate antisense oligonucleotides in vivo
-
Skorski T, Perrotti D, Nieborowska-Skorska M, Gryaznov S, Calabretta B: Antileukemia effect of c-myc N3′→P5′ phosphoramidate antisense oligonucleotides in vivo. Proc Natl Acad Sci USA (1997) 94(8):3966-3971.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.8
, pp. 3966-3971
-
-
Skorski, T.1
Perrotti, D.2
Nieborowska-Skorska, M.3
Gryaznov, S.4
Calabretta, B.5
-
30
-
-
0000015743
-
-
Dias N, Stein CA: Antisense oligonucleotides: Basic concepts and mechanisms. Mol Cancer Ther (2002) 1(5):347-355. • This review summarized various chemical modifications of antisense oligonucleotides and discussed advantages of various chemical modifications.
-
Dias N, Stein CA: Antisense oligonucleotides: Basic concepts and mechanisms. Mol Cancer Ther (2002) 1(5):347-355. • This review summarized various chemical modifications of antisense oligonucleotides and discussed advantages of various chemical modifications.
-
-
-
-
31
-
-
0033555551
-
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression
-
McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM: Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-α expression. J Biol Chem (1999) 274(3):1715-1722.
-
(1999)
J Biol Chem
, vol.274
, Issue.3
, pp. 1715-1722
-
-
McKay, R.A.1
Miraglia, L.J.2
Cummins, L.L.3
Owens, S.R.4
Sasmor, H.5
Dean, N.M.6
-
32
-
-
0032052790
-
Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells
-
Giles RV, Spiller DG, Grzybowski J, Clark RE, Nicklin P, Tidd DM: Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells. Nucleic Acids Res (1998) 26(7):1567-1575.
-
(1998)
Nucleic Acids Res
, vol.26
, Issue.7
, pp. 1567-1575
-
-
Giles, R.V.1
Spiller, D.G.2
Grzybowski, J.3
Clark, R.E.4
Nicklin, P.5
Tidd, D.M.6
-
33
-
-
0030909609
-
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
-
Agrawal S, Jiang Z, Zhao Q, Shaw D, Cai Q, Roskey A, Channavajjala L, Saxinger C, Zhang R: Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies. Proc Natl Acad Sci USA (1997) 94(6):2620-2625.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.6
, pp. 2620-2625
-
-
Agrawal, S.1
Jiang, Z.2
Zhao, Q.3
Shaw, D.4
Cai, Q.5
Roskey, A.6
Channavajjala, L.7
Saxinger, C.8
Zhang, R.9
-
34
-
-
0031727487
-
Impact of mixed-backbone oligonucleotides on target binding affinity and target cleaving specificity and selectivity by Escherichia coli RNase H
-
Shen LX, Kandimalla ER, Agrawal S: Impact of mixed-backbone oligonucleotides on target binding affinity and target cleaving specificity and selectivity by Escherichia coli RNase H. Bioorg Med Chem (1998) 6(10):1695-1705.
-
(1998)
Bioorg Med Chem
, vol.6
, Issue.10
, pp. 1695-1705
-
-
Shen, L.X.1
Kandimalla, E.R.2
Agrawal, S.3
-
35
-
-
0031910668
-
Pharmacokinetics and metabolism of an oligodeoxynucleotide phosphorothioate (GEM91) in cynomolgus monkeys following intravenous infusion
-
Grindel JM, Musick TJ, Jiang Z, Roskey A, Agrawal S: Pharmacokinetics and metabolism of an oligodeoxynucleotide phosphorothioate (GEM91) in cynomolgus monkeys following intravenous infusion. Antisense Nucleic Acid Drug Dev (1998) 8(1): 43-52.
-
(1998)
Antisense Nucleic Acid Drug Dev
, vol.8
, Issue.1
, pp. 43-52
-
-
Grindel, J.M.1
Musick, T.J.2
Jiang, Z.3
Roskey, A.4
Agrawal, S.5
-
36
-
-
0028934855
-
Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1
-
Zhang R, Diasio RB, Lu Z, Liu T, Jiang Z, Galbraith WM, Agrawal S: Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1. Biochem Pharmacol (1995) 49(7):929-939.
-
(1995)
Biochem Pharmacol
, vol.49
, Issue.7
, pp. 929-939
-
-
Zhang, R.1
Diasio, R.B.2
Lu, Z.3
Liu, T.4
Jiang, Z.5
Galbraith, W.M.6
Agrawal, S.7
-
37
-
-
0033763150
-
Pharmacokinetic and toxicity profile of a phosphorothioate oligonucleotide following inhalation delivery to lung in mice
-
Templin MV, Levin AA, Graham MJ, Aberg PM, Axelsson BI, Butler M, Geary RS, Bennett CF: Pharmacokinetic and toxicity profile of a phosphorothioate oligonucleotide following inhalation delivery to lung in mice. Antisense Nucleic Acid Drug Dev (2000) 10(5):359-368.
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, Issue.5
, pp. 359-368
-
-
Templin, M.V.1
Levin, A.A.2
Graham, M.J.3
Aberg, P.M.4
Axelsson, B.I.5
Butler, M.6
Geary, R.S.7
Bennett, C.F.8
-
38
-
-
30944443047
-
Antisense- and RNA interference-based therapeutic strategies in allergy
-
Popescu FD: Antisense- and RNA interference-based therapeutic strategies in allergy. J Cell Mol Med (2005) 9(4):840-853.
-
(2005)
J Cell Mol Med
, vol.9
, Issue.4
, pp. 840-853
-
-
Popescu, F.D.1
-
39
-
-
33847607512
-
Anti-inflammatory activity of inhaled IL-4 receptor-α antisense oligonucleotide in mice
-
Karras JG, Crosby JR, Guha M, Tung D, Miller DA, Gaarde WA, Geary RS, Monia BP, Gregory SA: Anti-inflammatory activity of inhaled IL-4 receptor-α antisense oligonucleotide in mice. Am J Respir Cell Mol Biol (2007) 36(3):276-285.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, Issue.3
, pp. 276-285
-
-
Karras, J.G.1
Crosby, J.R.2
Guha, M.3
Tung, D.4
Miller, D.A.5
Gaarde, W.A.6
Geary, R.S.7
Monia, B.P.8
Gregory, S.A.9
-
40
-
-
0026625347
-
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness
-
Bentley AM, Menz G, Storz C, Robinson DS, Bradley B, Jeffery PK, Durham SR, Kay AB: Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness. Am Rev Respir Dis (1992) 146(2):500-506.
-
(1992)
Am Rev Respir Dis
, vol.146
, Issue.2
, pp. 500-506
-
-
Bentley, A.M.1
Menz, G.2
Storz, C.3
Robinson, D.S.4
Bradley, B.5
Jeffery, P.K.6
Durham, S.R.7
Kay, A.B.8
-
41
-
-
0039101293
-
Asthma: An inflammatory mediator soup
-
Bjornsdottir US, Cypcar DM: Asthma: An inflammatory mediator soup. Allergy (1999) 54(49):55-61.
-
(1999)
Allergy
, vol.54
, Issue.49
, pp. 55-61
-
-
Bjornsdottir, U.S.1
Cypcar, D.M.2
-
43
-
-
0038387445
-
To respond or not to respond: T cells in allergic asthma
-
Herrick CA, Bottomly K: To respond or not to respond: T cells in allergic asthma. Nat Rev Immunol (2003) 3(5):405-412.
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.5
, pp. 405-412
-
-
Herrick, C.A.1
Bottomly, K.2
-
44
-
-
0029828994
-
Transcription factor GATA-3 is required for development of the T-cell lineage
-
Ting CN, Olson MC, Barton KP, Leiden JM: Transcription factor GATA-3 is required for development of the T-cell lineage. Nature (1996) 384(6608):474-478.
-
(1996)
Nature
, vol.384
, Issue.6608
, pp. 474-478
-
-
Ting, C.N.1
Olson, M.C.2
Barton, K.P.3
Leiden, J.M.4
-
45
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA: The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell (1997) 89(4):587-596.
-
(1997)
Cell
, vol.89
, Issue.4
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
46
-
-
0036083901
-
Ragweed-induced expression of GATA-3, IL-4, and IL-5 by eosinophils in the lungs of allergic C57BL/6J mice
-
Justice JP, Borchers MT, Lee JJ, Rowan WH, Shibata Y, Van Scott MR: Ragweed-induced expression of GATA-3, IL-4, and IL-5 by eosinophils in the lungs of allergic C57BL/6J mice. Am J Physiol Lung Cell Mol Physiol (2002) 282(2):L302-L309.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
, Issue.2
-
-
Justice, J.P.1
Borchers, M.T.2
Lee, J.J.3
Rowan, W.H.4
Shibata, Y.5
Van Scott, M.R.6
-
47
-
-
0035806279
-
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression
-
Finotto S, De Sanctis GT, Lehr HA, Herz U, Buerke M, Schipp M, Bartsch B, Atreya R, Schmitt E, Galle PR, Renz H et al: Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression. J Exp Med (2001) 193(11):1247-1260.
-
(2001)
J Exp Med
, vol.193
, Issue.11
, pp. 1247-1260
-
-
Finotto, S.1
De Sanctis, G.T.2
Lehr, H.A.3
Herz, U.4
Buerke, M.5
Schipp, M.6
Bartsch, B.7
Atreya, R.8
Schmitt, E.9
Galle, P.R.10
Renz, H.11
-
48
-
-
0035113157
-
Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthma
-
Finotto S, Buerke M, Lingnau K, Schmitt E, Galle PR, Neurath MF: Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthma. J Allergy Clin Immunol (2001) 107(2):279-286.
-
(2001)
J Allergy Clin Immunol
, vol.107
, Issue.2
, pp. 279-286
-
-
Finotto, S.1
Buerke, M.2
Lingnau, K.3
Schmitt, E.4
Galle, P.R.5
Neurath, M.F.6
-
49
-
-
14944350956
-
Inhaled p38α mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice
-
Duan W, Chan JH, McKay K, Crosby JR, Choo HH, Leung BP, Karras JG, Wong WS: Inhaled p38α mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. Am J Respir Crit Care Med (2005) 171(6):571-578.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.6
, pp. 571-578
-
-
Duan, W.1
Chan, J.H.2
McKay, K.3
Crosby, J.R.4
Choo, H.H.5
Leung, B.P.6
Karras, J.G.7
Wong, W.S.8
-
50
-
-
0031807018
-
The Syk protein tyrosine kinase is essential for Fc-γ receptor signaling in macrophages and neutrophils
-
Kiefer F, Brumell J, Al-Alawi N, Latour S, Cheng A, Veillette A, Grinstein S, Pawson T: The Syk protein tyrosine kinase is essential for Fc-γ receptor signaling in macrophages and neutrophils. Mol Cell Biol (1998) 18(7):4209-4220.
-
(1998)
Mol Cell Biol
, vol.18
, Issue.7
, pp. 4209-4220
-
-
Kiefer, F.1
Brumell, J.2
Al-Alawi, N.3
Latour, S.4
Cheng, A.5
Veillette, A.6
Grinstein, S.7
Pawson, T.8
-
51
-
-
0030829551
-
A critical role for Syk in signal transduction and phagocytosis mediated by Fc-γ receptors on macrophages
-
Crowley MT, Costello PS, Fitzer-Attas CJ, Turner M, Meng F, Lowell C, Tybulewicz VL, DeFranco AL: A critical role for Syk in signal transduction and phagocytosis mediated by Fc-γ receptors on macrophages. J Exp Med (1997) 186(7):1027-1039.
-
(1997)
J Exp Med
, vol.186
, Issue.7
, pp. 1027-1039
-
-
Crowley, M.T.1
Costello, P.S.2
Fitzer-Attas, C.J.3
Turner, M.4
Meng, F.5
Lowell, C.6
Tybulewicz, V.L.7
DeFranco, A.L.8
-
52
-
-
0037100457
-
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase
-
Stenton GR, Ulanova M, Dery RE, Merani S, Kim MK, Gilchrist M, Puttagunta L, Musat-Marcu S, James D, Schreiber AD, Befus AD: Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. J Immunol (2002) 169(2):1028-1036.
-
(2002)
J Immunol
, vol.169
, Issue.2
, pp. 1028-1036
-
-
Stenton, G.R.1
Ulanova, M.2
Dery, R.E.3
Merani, S.4
Kim, M.K.5
Gilchrist, M.6
Puttagunta, L.7
Musat-Marcu, S.8
James, D.9
Schreiber, A.D.10
Befus, A.D.11
-
53
-
-
78651040655
-
Recovery of cytopathogenic agent from chimpanzees with coryza
-
Blount RE Jr, Morris JA, Savage RE: Recovery of cytopathogenic agent from chimpanzees with coryza. Proc Soc Exp Biol Med (1956) 92(3):544-549.
-
(1956)
Proc Soc Exp Biol Med
, vol.92
, Issue.3
, pp. 544-549
-
-
Blount Jr, R.E.1
Morris, J.A.2
Savage, R.E.3
-
54
-
-
0000089226
-
Respiratory syncytial virus
-
Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Strans SE Eds, Lippincott-Raven, Philadelphia, PA, USA
-
Collins PL, McIntosh K, Chanock RM: Respiratory syncytial virus. In: Field's Virology. Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Strans SE (Eds), Lippincott-Raven, Philadelphia, PA, USA (1996):1313-1351.
-
(1996)
Field's Virology
, pp. 1313-1351
-
-
Collins, P.L.1
McIntosh, K.2
Chanock, R.M.3
-
55
-
-
33845497739
-
Brief report: Respiratory syncytial virus activity - United States, 2005-2006
-
Fowlkes AL, Fry AM, Anderson LJ: Brief report: Respiratory syncytial virus activity - United States, 2005-2006. Morb Mortal Wkly Rep (2006) 55(47):1277-1279.
-
(2006)
Morb Mortal Wkly Rep
, vol.55
, Issue.47
, pp. 1277-1279
-
-
Fowlkes, A.L.1
Fry, A.M.2
Anderson, L.J.3
-
56
-
-
33747106534
-
Respiratory syncytial virus infections: Recent prospects for control
-
Sidwell RW, Barnard DL: Respiratory syncytial virus infections: Recent prospects for control. Antiviral Res (2006) 71(2-3):379-390.
-
(2006)
Antiviral Res
, vol.71
, Issue.2-3
, pp. 379-390
-
-
Sidwell, R.W.1
Barnard, D.L.2
-
57
-
-
2442468768
-
-
Maggon K, Barik S: New drugs and treatment for respiratory syncytial virus. Rev Med Virol (2004) 14(3):149-168. • A comprehensive review on existing treatments for RSV.
-
Maggon K, Barik S: New drugs and treatment for respiratory syncytial virus. Rev Med Virol (2004) 14(3):149-168. • A comprehensive review on existing treatments for RSV.
-
-
-
-
58
-
-
0032555288
-
Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA
-
Player MR, Barnard DL, Torrence PF: Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA. Proc Natl Acad Sci USA (1998) 95(15):8874-8879.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.15
, pp. 8874-8879
-
-
Player, M.R.1
Barnard, D.L.2
Torrence, P.F.3
-
59
-
-
0031036222
-
Inhibition of respiratory syncytial virus replication by antisense oligodeoxyribonucleotides
-
Jairath S, Vargas PB, Hamlin HA, Field AK, Kilkuskie RE: Inhibition of respiratory syncytial virus replication by antisense oligodeoxyribonucleotides. Antiviral Res (1997) 33(3):201-213.
-
(1997)
Antiviral Res
, vol.33
, Issue.3
, pp. 201-213
-
-
Jairath, S.1
Vargas, P.B.2
Hamlin, H.A.3
Field, A.K.4
Kilkuskie, R.E.5
-
60
-
-
0036061381
-
-
Leaman DW, Longano FJ, Okicki JR, Soike KF, Torrence PF, Silverman RH, Cramer H: Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense. Virology (2002) 292(1):70-77. • The first report of the successful intranasal application of an unusual antisense ODN against respiratory infection in an animal model.
-
Leaman DW, Longano FJ, Okicki JR, Soike KF, Torrence PF, Silverman RH, Cramer H: Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense. Virology (2002) 292(1):70-77. • The first report of the successful intranasal application of an unusual antisense ODN against respiratory infection in an animal model.
-
-
-
-
61
-
-
0032545933
-
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 391(6669):806-811. •• The discovery of RNAi is reported. This research led to the Nobel Prize (2006) being awarded to the researchers.
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 391(6669):806-811. •• The discovery of RNAi is reported. This research led to the Nobel Prize (2006) being awarded to the researchers.
-
-
-
-
62
-
-
0035920256
-
Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice
-
Yet SF, Tian R, Layne MD, Wang ZY, Maemura K, Solovyeva M, Ith B, Melo LG, Zhang L, Ingwall JS, Dzau VJ et al: Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice. Circ Res (2001) 89(2):168-173.
-
(2001)
Circ Res
, vol.89
, Issue.2
, pp. 168-173
-
-
Yet, S.F.1
Tian, R.2
Layne, M.D.3
Wang, Z.Y.4
Maemura, K.5
Solovyeva, M.6
Ith, B.7
Melo, L.G.8
Zhang, L.9
Ingwall, J.S.10
Dzau, V.J.11
-
64
-
-
0032900940
-
Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury
-
Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, Choi AM: Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest (1999) 103(7):1047-1054.
-
(1999)
J Clin Invest
, vol.103
, Issue.7
, pp. 1047-1054
-
-
Otterbein, L.E.1
Kolls, J.K.2
Mantell, L.L.3
Cook, J.L.4
Alam, J.5
Choi, A.M.6
-
65
-
-
0029156942
-
Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: Protective effect against heme and hemoglobin toxicity
-
Abraham NG, Lavrovsky Y, Schwartzman ML, Stoltz RA, Levere RD, Gerritsen ME, Shibahara S, Kappas A: Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: Protective effect against heme and hemoglobin toxicity. Proc Natl Acad Sci USA (1995) 92(15):6798-6802.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.15
, pp. 6798-6802
-
-
Abraham, N.G.1
Lavrovsky, Y.2
Schwartzman, M.L.3
Stoltz, R.A.4
Levere, R.D.5
Gerritsen, M.E.6
Shibahara, S.7
Kappas, A.8
-
66
-
-
1642265345
-
Carbon monoxide heme oxygenase-1 in lung disease
-
Marczin N, Kharitonov S, Yacoub M, Barnes P Eds, Marcel Dekker Inc, New York, NY, USA
-
Lee PJ, Otterbein LE, Sethi J, Sasidhar M, Choi AM: Carbon monoxide heme oxygenase-1 in lung disease. In: Disease Markers in Exhaled Breath. Marczin N, Kharitonov S, Yacoub M, Barnes P (Eds), Marcel Dekker Inc, New York, NY, USA (2002):117-127.
-
(2002)
Disease Markers in Exhaled Breath
, pp. 117-127
-
-
Lee, P.J.1
Otterbein, L.E.2
Sethi, J.3
Sasidhar, M.4
Choi, A.M.5
-
67
-
-
1642291631
-
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis
-
Zhang X, Shan P, Jiang D, Noble PW, Abraham NG, Kappas A, Lee PJ: Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J Biol Chem (2004) 279(11):10677-10684.
-
(2004)
J Biol Chem
, vol.279
, Issue.11
, pp. 10677-10684
-
-
Zhang, X.1
Shan, P.2
Jiang, D.3
Noble, P.W.4
Abraham, N.G.5
Kappas, A.6
Lee, P.J.7
-
68
-
-
33645770464
-
Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis
-
Qureshi ST, Zhang X, Aberg E, Bousette N, Giaid A, Shan P, Medzhitov RM, Lee PJ: Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis. J Immunol (2006) 176(8):4950-4958.
-
(2006)
J Immunol
, vol.176
, Issue.8
, pp. 4950-4958
-
-
Qureshi, S.T.1
Zhang, X.2
Aberg, E.3
Bousette, N.4
Giaid, A.5
Shan, P.6
Medzhitov, R.M.7
Lee, P.J.8
-
69
-
-
18644366031
-
Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis
-
Matsuyama W, Watanabe M, Shirahama Y, Oonakahara K, Higashimoto I, Yoshimura T, Osame M, Arimura K: Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis. J Immunol (2005) 174(10):6490-6498.
-
(2005)
J Immunol
, vol.174
, Issue.10
, pp. 6490-6498
-
-
Matsuyama, W.1
Watanabe, M.2
Shirahama, Y.3
Oonakahara, K.4
Higashimoto, I.5
Yoshimura, T.6
Osame, M.7
Arimura, K.8
-
70
-
-
33644649577
-
Discoidin domain receptor 1 contributes to the survival of lung fibroblast in idiopathic pulmonary fibrosis
-
Matsuyama W, Watanabe M, Shirahama Y, Mitsuyama H, Higashimoto I, Osame M, Arimura K: Discoidin domain receptor 1 contributes to the survival of lung fibroblast in idiopathic pulmonary fibrosis. Am J Pathol (2006) 168(3):866-877.
-
(2006)
Am J Pathol
, vol.168
, Issue.3
, pp. 866-877
-
-
Matsuyama, W.1
Watanabe, M.2
Shirahama, Y.3
Mitsuyama, H.4
Higashimoto, I.5
Osame, M.6
Arimura, K.7
-
71
-
-
33747113061
-
Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis
-
Avivi-Green C, Singal M, Vogel WF: Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med (2006) 174(4):420-427.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, Issue.4
, pp. 420-427
-
-
Avivi-Green, C.1
Singal, M.2
Vogel, W.F.3
-
72
-
-
31144476253
-
Suppression of discoidin domain receptor 1 by RNA interference attenuates lung inflammation
-
Matsuyama W, Watanabe M, Shirahama Y, Hirano R, Mitsuyama H, Higashimoto I, Osame M, Arimura K: Suppression of discoidin domain receptor 1 by RNA interference attenuates lung inflammation. J Immunol (2006) 176(3):1928-1936.
-
(2006)
J Immunol
, vol.176
, Issue.3
, pp. 1928-1936
-
-
Matsuyama, W.1
Watanabe, M.2
Shirahama, Y.3
Hirano, R.4
Mitsuyama, H.5
Higashimoto, I.6
Osame, M.7
Arimura, K.8
-
73
-
-
19044381013
-
-
Bitko V, Barik S. Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses. BMC Microbiol (2001) 1:34. •• This is the first report of RNAi as an antiviral agent.
-
Bitko V, Barik S. Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses. BMC Microbiol (2001) 1:34. •• This is the first report of RNAi as an antiviral agent.
-
-
-
-
74
-
-
0038617774
-
The classification of viruses infecting the respiratory tract
-
Mackie PL: The classification of viruses infecting the respiratory tract. Paediatr Respir Rev (2003) 4(2):84-90.
-
(2003)
Paediatr Respir Rev
, vol.4
, Issue.2
, pp. 84-90
-
-
Mackie, P.L.1
-
75
-
-
34247244992
-
-
Centers for Disease Control and Prevention, Atlanta, GA, USA
-
The influenza (flu) viruses: Centers for Disease Control and Prevention, Atlanta, GA, USA (2006). http://www.cdc.gov/flu/about/fluviruses. htm
-
(2006)
The influenza (flu) viruses
-
-
-
76
-
-
0032517071
-
Benefits of influenza vaccination for low-, intermediate-, and high-risk senior citizens
-
Nichol KL, Wuorenma J, von Sternberg T: Benefits of influenza vaccination for low-, intermediate-, and high-risk senior citizens. Arch Intern Med (1998) 158(16):1769-1776.
-
(1998)
Arch Intern Med
, vol.158
, Issue.16
, pp. 1769-1776
-
-
Nichol, K.L.1
Wuorenma, J.2
von Sternberg, T.3
-
77
-
-
0023503015
-
Survey of underlying conditions of persons hospitalized with acute respiratory disease during influenza epidemics in Houston, 1978-1981
-
Glezen WP, Decker M, Perrotta DM: Survey of underlying conditions of persons hospitalized with acute respiratory disease during influenza epidemics in Houston, 1978-1981. Am Rev Respir Dis (1987) 136(3):550- 555.
-
(1987)
Am Rev Respir Dis
, vol.136
, Issue.3
, pp. 550-555
-
-
Glezen, W.P.1
Decker, M.2
Perrotta, D.M.3
-
78
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J: RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA (2003) 100(5):2718-2723.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.5
, pp. 2718-2723
-
-
Ge, Q.1
McManus, M.T.2
Nguyen, T.3
Shen, C.H.4
Sharp, P.A.5
Eisen, H.N.6
Chen, J.7
-
79
-
-
13444252624
-
Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene
-
Zhang W, Yang H, Kong X, Mohapatra S, San Juan-Vergara H, Hellermann G, Behera S, Singam R, Lockey RF, Mohapatra SS: Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene. Nat Med (2005) 11(1):56-62.
-
(2005)
Nat Med
, vol.11
, Issue.1
, pp. 56-62
-
-
Zhang, W.1
Yang, H.2
Kong, X.3
Mohapatra, S.4
San Juan-Vergara, H.5
Hellermann, G.6
Behera, S.7
Singam, R.8
Lockey, R.F.9
Mohapatra, S.S.10
-
80
-
-
0032889254
-
Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein
-
Teng MN, Collins PL: Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein. J Virol (1999) 73(1):466-473.
-
(1999)
J Virol
, vol.73
, Issue.1
, pp. 466-473
-
-
Teng, M.N.1
Collins, P.L.2
-
81
-
-
0034691566
-
Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo
-
Jin H, Zhou H, Cheng X, Tang R, Munoz M, Nguyen N: Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo. Virology (2000) 273(1):210-218.
-
(2000)
Virology
, vol.273
, Issue.1
, pp. 210-218
-
-
Jin, H.1
Zhou, H.2
Cheng, X.3
Tang, R.4
Munoz, M.5
Nguyen, N.6
-
82
-
-
0033803734
-
Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees
-
Teng MN, Whitehead SS, Bermingham A, St Claire M, Elkins WR, Murphy BR, Collins PL: Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees. J Virol (2000) 74(19):9317-9321.
-
(2000)
J Virol
, vol.74
, Issue.19
, pp. 9317-9321
-
-
Teng, M.N.1
Whitehead, S.S.2
Bermingham, A.3
St Claire, M.4
Elkins, W.R.5
Murphy, B.R.6
Collins, P.L.7
-
83
-
-
32044433987
-
The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humans
-
Wright PF, Karron RA, Madhi SA, Treanor JJ, King JC, O'Shea A, Ikizler MR, Zhu Y, Collins PL, Cutland C, Randolph VB et al: The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humans. J Infect Dis (2006) 193(4):573-581.
-
(2006)
J Infect Dis
, vol.193
, Issue.4
, pp. 573-581
-
-
Wright, P.F.1
Karron, R.A.2
Madhi, S.A.3
Treanor, J.J.4
King, J.C.5
O'Shea, A.6
Ikizler, M.R.7
Zhu, Y.8
Collins, P.L.9
Cutland, C.10
Randolph, V.B.11
-
84
-
-
20044387307
-
Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and α/β interferon responsiveness
-
Lo MS, Brazas RM, Holtzman MJ: Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and α/β interferon responsiveness. J Virol (2005) 79(14):9315-9319.
-
(2005)
J Virol
, vol.79
, Issue.14
, pp. 9315-9319
-
-
MS, L.1
Brazas, R.M.2
Holtzman, M.J.3
-
85
-
-
33744903380
-
The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response
-
Kotelkin A, Belyakov IM, Yang L, Berzofsky JA, Collins PL, Bukreyev A: The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response. J Virol (2006) 80(12):5958-5967.
-
(2006)
J Virol
, vol.80
, Issue.12
, pp. 5958-5967
-
-
Kotelkin, A.1
Belyakov, I.M.2
Yang, L.3
Berzofsky, J.A.4
Collins, P.L.5
Bukreyev, A.6
-
86
-
-
30044431891
-
Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction
-
Ramaswamy M, Shi L, Varga SM, Barik S, Behlke MA, Look DC: Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction. Virology (2006) 344(2):328-339.
-
(2006)
Virology
, vol.344
, Issue.2
, pp. 328-339
-
-
Ramaswamy, M.1
Shi, L.2
Varga, S.M.3
Barik, S.4
Behlke, M.A.5
Look, D.C.6
-
87
-
-
33846815515
-
Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-κB-dependent, interferon-independent mechanism and facilitate virus growth
-
Bitko V, Shulyayeva O, Mazumder B, Musiyenko A, Ramaswamy M, Look DC, Barik S: Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-κB-dependent, interferon-independent mechanism and facilitate virus growth. J Virol (2007) 81(4):1786-1795.
-
(2007)
J Virol
, vol.81
, Issue.4
, pp. 1786-1795
-
-
Bitko, V.1
Shulyayeva, O.2
Mazumder, B.3
Musiyenko, A.4
Ramaswamy, M.5
Look, D.C.6
Barik, S.7
-
88
-
-
0242717589
-
Coronavirus as a possible cause of severe acute respiratory syndrome
-
Peiris JS, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, Nicholls J, Yee WK, Yan WW, Cheung MT, Cheng VC et al: Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet (2003) 361(9366): 1319-1325.
-
(2003)
Lancet
, vol.361
, Issue.9366
, pp. 1319-1325
-
-
Peiris, J.S.1
Lai, S.T.2
Poon, L.L.3
Guan, Y.4
Yam, L.Y.5
Lim, W.6
Nicholls, J.7
Yee, W.K.8
Yan, W.W.9
Cheung, M.T.10
Cheng, V.C.11
-
89
-
-
34247179346
-
-
Basic information about SARS: Centers for Disease Control and Prevention, Atlanta, GA, USA (2005). http://www.cdc.gov/ncidod/sars/ factsheet.htm
-
Basic information about SARS: Centers for Disease Control and Prevention, Atlanta, GA, USA (2005). http://www.cdc.gov/ncidod/sars/ factsheet.htm
-
-
-
-
90
-
-
33750071716
-
Emerging respiratory viruses: Challenges and vaccine strategies
-
Gillim-Ross L, Subbarao K: Emerging respiratory viruses: Challenges and vaccine strategies. Clin Microbiol Rev (2006) 19(4):614-636.
-
(2006)
Clin Microbiol Rev
, vol.19
, Issue.4
, pp. 614-636
-
-
Gillim-Ross, L.1
Subbarao, K.2
-
91
-
-
21344471227
-
An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus
-
Qin C, Wang J, Wei Q, She M, Marasco WA, Jiang H, Tu X, Zhu H, Ren L, Gao H, Guo L et al: An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus. J Pathol (2005) 206(3):251-259.
-
(2005)
J Pathol
, vol.206
, Issue.3
, pp. 251-259
-
-
Qin, C.1
Wang, J.2
Wei, Q.3
She, M.4
Marasco, W.A.5
Jiang, H.6
Tu, X.7
Zhu, H.8
Ren, L.9
Gao, H.10
Guo, L.11
-
92
-
-
3042736199
-
Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus
-
Zheng BJ, Guan Y, Tang Q, Du C, Xie FY, He ML, Chan KW, Wong KL, Lader E, Woodle MC, Lu PY et al: Prophylactic and therapeutic effects of small interfering RNA targeting SARS-coronavirus. Antivir Ther (2004) 9(3):365-374.
-
(2004)
Antivir Ther
, vol.9
, Issue.3
, pp. 365-374
-
-
Zheng, B.J.1
Guan, Y.2
Tang, Q.3
Du, C.4
Xie, F.Y.5
He, M.L.6
Chan, K.W.7
Wong, K.L.8
Lader, E.9
Woodle, M.C.10
Lu, P.Y.11
-
94
-
-
34247261833
-
-
Sirna Therapeutics Inc, San Francisco, CA, USA
-
Therapeutic pipeline: Sirna Therapeutics Inc, San Francisco, CA, USA (2007). http://www.sirna.com/wt/page/product_pipeline
-
(2007)
Therapeutic pipeline
-
-
-
95
-
-
84911392093
-
-
Nastech Pharmaceutical Co, Bothell, WA, USA
-
Pipeline: Nastech Pharmaceutical Co, Bothell, WA, USA (2007). http://www.nastech.com/nastech/pipeline
-
(2007)
Pipeline
-
-
-
96
-
-
33748054817
-
RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
-
Howard KA, Rahbek UL, Liu X, Damgaard CK, Glud SZ, Andersen MO, Hovgaard MB, Schmitz A, Nyengaard JR, Besenbacher F, Kjems J: RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. Mol Ther (2006) 14(4):476-484.
-
(2006)
Mol Ther
, vol.14
, Issue.4
, pp. 476-484
-
-
Howard, K.A.1
Rahbek, U.L.2
Liu, X.3
Damgaard, C.K.4
Glud, S.Z.5
Andersen, M.O.6
Hovgaard, M.B.7
Schmitz, A.8
Nyengaard, J.R.9
Besenbacher, F.10
Kjems, J.11
-
97
-
-
4644302416
-
Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice
-
Massaro D, Massaro GD, Clerch LB: Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice. Am J Physiol Lung Cell Mol Physiol (2004) 287(5):L1066-L1070.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, Issue.5
-
-
Massaro, D.1
Massaro, G.D.2
Clerch, L.B.3
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