Rodent models of allergic rhinitis: Relevance to human pathophysiology

Current Allergy and Asthma Reports

Volumn 7, Issue 2, 2007, Pages 134-140

  Wagner, James G ^a   Harkema, Jack R ^b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CHEMOATTRACTANT; CYTOKINE; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 5; LEUKOTRIENE; NITRIC OXIDE; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN; THROMBOCYTE ACTIVATING FACTOR; TRYPTASE;

AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; ALLERGIC RHINITIS; ASTHMA; BASOPHIL; BREATHING MECHANICS; DISEASE ASSOCIATION; DISEASE MODEL; GENETICS; GUINEA PIG; HISTOPATHOLOGY; IMMUNOLOGY; MAST CELL; MEDICAL ASSESSMENT; MEDICAL RESEARCH; MUCUS SECRETION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NOSE OBSTRUCTION; OUTCOME ASSESSMENT; PATHOLOGICAL ANATOMY; PATHOPHYSIOLOGY; PROTEIN SECRETION; PROVOCATION TEST; RESPIRATORY SYSTEM; REVIEW; RODENT; SENSITIZATION; SNEEZING; STRAIN DIFFERENCE;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; CHRONIC DISEASE; CONJUNCTIVITIS, ALLERGIC; DISEASE MODELS, ANIMAL; GUINEA PIGS; HUMANS; MICE; NASAL OBSTRUCTION; RATS; RESPIRATORY SYSTEM; RHINITIS, ALLERGIC, PERENNIAL; RHINITIS, ALLERGIC, SEASONAL;

EID: 34248327274     PISSN: 15297322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11882-007-0011-5     Document Type: Review

References (49)

1. Asher MI, Montefort S, Bjorksten B, et al.: Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006, 368:733-743.
2. Gaugris S, Sazonov-Kocevar V, Thomas M: Burden of concomitant allergic rhinitis in adults with asthma. J Asthma 2006, 43:1-7.
3. Ponikau JU, Sherris DA, Kephart GM, et al.: Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: is the histopathology similar to asthma? J Allergy Clin Immunol 2003, 112:877-882.
4. Ciprandi G, Cirillo I: The lower airway pathology of rhinitis. J Allergy Clin Immunol 2006, 118:1105-1109.
5. Greisner WA 3rd, Settipane RJ, Settipane GA: Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students. Allergy Asthma Proc 1998, 19:185-188.
6. Chanez P, Vignola AM, Vic P, et al.: Comparison between nasal and bronchial inflammation in asthmatic and control subjects. Am J Respir Crit Care Med 1999, 159:588-595.
7. Bousquet J, Van Cauwenberge P, Khaltaev N: Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001, 108:S147-334.
8. McMillan SJ, Lloyd CM: Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin Exp Allergy 2004, 34:497-507.
9. Wegmann M, Fehrenbach H, Fehrenbach A, et al.: Involvement of distal airways in a chronic model of experimental asthma. Clin Exp Allergy 2005, 35:1263-1271.
10. Yu M, Tsai M, Tam SY, et al.: Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006, 116:1633-1641.
11. Southam DS, Dolovich M, O'Byrne PM, et al.: Distribution of intranasal instillations in mice: effects of volume, time, body position, and anesthesia. Am J Pbysiol Lung Cell Mol Pbysiol 2002, 282:L833-839.
12. Pauluhn J, Mohr U: Experimental approaches to evaluate respiratory allergy in animal models. Exp Toxicol Pathol 2005, 56:203-234.
13. Farraj AK, Harkema JR, Kaminski NE: Topical application versus intranasal instillation: a qualitative comparison of the effect of the route of sensitization on trimellitic anhydride-induced allergic rhinitis in A/J mice. Toxicol Sci 2006, 92:321-328.
14. Widdicombe JG: Nasal pathophysiology. Respir Med 1990, 84(Suppl A):3-9; discussion 9-10.
15. Patou J, De Smedt H, van Cauwenberge P, et al.: Pathophysiology of nasal obstruction and meta-analysis of early and late effects of levocetirizine. Clin Exp Allergy 2006, 36:972-981.
16. Szelenyi I, Marx D, Jahn W: Animal models of allergic rhinitis. Arzneimittelforschung 2000, 50:1037-1042.
17. Al Suleimani M, Ying D, Walker MJ: A comprehensive model of allergic rhinitis in guinea pigs. J Pharmacol Toxicol Methods 2006, Epub ahead of print.
18. Kaise T, Ukai K, Pedersen OF, et al.: Accuracy of measurement of acoustic rhinometry applied to small experimental animals. Am J Rhinol 1999, 13:125-129.
19. Lomask M: Further exploration of the Penh parameter. Exp Toxicol Pathol 2006, 57(Suppl 2):13-20.
20. Bates J, Irvin C, Brusasco V, et al.: The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol 2004, 31:373-374.
21. Nakaya M, Dohi M, Okunishi K, et al.: Noninvasive system for evaluating allergen-induced nasal hypersensitivity in murine allergic rhinitis. Lab Invest 2006, 86:917-926.
22. Bates JH, Irvin CG: Measuring lung function in mice: the phenotyping uncertainty principle. J Appl Physiol 2003, 94:1297-1306.
23. Miyahara S, Miyahara N, Takeda K, et al.: Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI). J Allergy Clin Immunol 2005, 116:1020-1027.
24. Miyahara S, Miyahara N, Matsubara S, et al.: IL-13 is essential to the late-phase response in allergic rhinitis. J Allergy Clin Immunol 2006, 118:1110-1116.
25. Zhao Y, Woo JK, Leung PC, et al.: Symptomatic and pathophysiological observations in a modified animal model of allergic rhinitis. Rhinology 2005, 43:47-54.
26. Pawankar R: Allergic rhinitis and asthma: are they manifestations of one syndrome? Clin Exp Allergy 2006, 36:1-4.
27. Li J, Saito H, Crawford L, et al.: Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology 2005, 114:386-396.
28. Fukuda S, Midoro K, Gyoten M, et al.: Effects of TAK-427 on acute nasal symptoms and nasal obstruction in guinea pig model of experimental allergic rhinitis. Eur J Pharmacol 2003, 476:239-247.
29. McLeod RL, Young SS, Erickson CH, et al.: Characterization of nasal obstruction in the allergic guinea pig using the forced oscillation method. J Pharmacol Toxicol Methods 2002, 48:153-159.
30. Ciprandi G, Cirillo I, Vizzaccaro A, et al.: Airway function and nasal inflammation in seasonal allergic rhinitis and asthma. Clin Exp Allergy 2004, 34:891-896.
31. Harkema JR: Comparative aspects of nasal airway anatomy: relevance to inhalation toxicology. Toxicol Pathol 1991, 19:321-336.
32. Harkema JR, Carey SA, Wagner JG: The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium. Toxicol Pathol 2006, 34:252-269.
33. Gross EA, Swenberg JA, Fields S, et al.: Comparative morphometry of the nasal cavity in rats and mice. J Anat 1982, 135:83-88.
34. Wagner JG, Hotchkiss JA, Harkema JR: Enhancement of nasal inflammatory and epithelial responses after ozone and allergen coexposure in Brown Norway rats. Toxicol Sci 2002, 67:284-294.
35. Berger G, Marom Z, Ophir D: Goblet cell density of the inferior turbinates in patients with perennial allergic and nonallergic rhinitis. Am J Rhinol 1997, 11:233-236.
36. Berger G, Moroz A, Marom Z, et al.: Inferior turbinate goblet cell secretion in patients with perennial allergic and nonallergic rhinitis. Am J Rhinol 1999, 13:473-477.
37. Ciprandi G, Cirillo I, Vizzaccaro A, et al.: Correlation of nasal inflammation and nasal airflow with forced expiratory volume in 1 second in patients with perennial allergic rhinitis and asthma. Ann Allergy Asthma Immunol 2004, 93:575-580.
38. Yamasaki M, Mizutani N, Sasaki K, et al.: No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. Eur J Pharmacol 2002, 439:159-169.
39. Singer M, Lefort J, Vargaftig BB: Granulocyte depletion and dexamethasone differentially modulate airways hyperreactivity, inflammation, mucus accumulation, and secretion induced by rmIL-13 or antigen. Am J Respir Cell Mol Biol 2002, 26:74-84.
40. Humbles AA, Lloyd CM, McMillan SJ, et al.: A critical role for eosinophils in allergic airways remodeling. Science 2004, 305:1776-1779.
41. Berger G, Goldberg A, Ophir D: The inferior turbinate mast cell population of patients with perennial allergic and nonallergic rhinitis. Am J Rhinol 1997, 11:63-66.
42. Amin K, Rinne J, Haahtela T, et al.: Inflammatory cell and epithelial characteristics of perennial allergic and nonallergic rhinitis with a symptom history of 1 to 3 years' duration. J Allergy Clin Immunol 2001, 107:249-257.
43. Fokkens WJ, Godthelp T, Holm AF, et al.: Dynamics of mast cells in the nasal mucosa of patients with allergic rhinitis and non-allergic controls: a biopsy study. Clin Exp Allergy 1992, 22:701-710.
44. Kawaguchi S, Majima Y, Sakakura Y: Nasal mast cells in experimentally induced allergic rhinitis in guinea-pigs. Clin Exp Allergy 1994, 24:238-244.
45. Lindsay R, Slaughter T, Britton-Webb J, et al.: Development of a murine model of chronic rhinosinusitis. Otolaryngol Head Neck Surg 2006, 134:724-730; discussion 731-722.
46. Salib RJ, Howarth PH: Remodelling of the upper airways in allergic rhinitis: is it a feature of the disease? Clin Exp Allergy 2003, 33:1629-1633.
47. Mery S, Gross EA, Joyner DR, et al.: Nasal diagrams: a tool for recording the distribution of nasal lesions in rats and mice. Toxicol Pathol 1994, 22:353-372.
48. Young JT: Histopathologic examination of the rat nasal cavity. Fundam Appl Toxicol 1981, 1:309-312.
49. Farraj AK, Harkema JR, Jan TR, et al.: Immune responses in the lung and local lymph node of A/J mice to intranasal sensitization and challenge with adjuvant-free ovalbumin. Toxicol Pathol 2003, 31:432-447.