Ozone exposure enhances endotoxin-induced mucous cell metaplasia in rat pulmonary airways

Toxicological Sciences

Volumn 74, Issue 2, 2003, Pages 437-446

  Wagner, James G ^a   Van Dyken, Steven J ^a   Wierenga, Janelle R ^a   Hotchkiss, Jon A ^a   Harkema, Jack R ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Inflammation; Lipopolysaccharide; Mucin; Mucous cell metaplasia; Neutrophil; Ozone

Indexed keywords

ENDOTOXIN; MESSENGER RNA; MUCIN; OZONE; SODIUM CHLORIDE;

AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DENSITY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; INFLAMMATORY CELL; LEUKOCYTE COUNT; LUNG LAVAGE; MALE; METAPLASIA; MICROSCOPY; MORPHOMETRICS; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RAT; RESPIRATORY TRACT MUCOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RODENT; STEADY STATE;

ADMINISTRATION, INTRANASAL; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DRUG SYNERGISM; INHALATION EXPOSURE; LIPOPOLYSACCHARIDES; LUNG; MALE; METAPLASIA; MUCINS; NEUTROPHIL INFILTRATION; NEUTROPHILS; OXIDANTS, PHOTOCHEMICAL; OZONE; PSEUDOMONAS AERUGINOSA; RATS; RATS, INBRED F344; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ANIMALIA; BACTERIA (MICROORGANISMS); RODENTIA;

EID: 0042591315     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg120     Document Type: Article

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