Binding of small molecules to cavity forming mutants of a de novo designed protein

Protein Science

Volumn 20, Issue 4, 2011, Pages 702-711

  Das, Aditi ^a,b   Wei, Yinan ^a,c   Pelczer, Istvan ^a   Hecht, Michael H ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Binary code for protein design; Cavity forming mutants; De novo design; NMR; Pulse field gradient spin echo; Saturation transfer difference

Indexed keywords

PEPTIDE LIBRARY; PHENYLALANINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; MUTANT; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEINS;

EID: 79953194094     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.601     Document Type: Article

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