Kinetics of anesthetic-induced conformational transitions in a four-α-helix bundle protein

Biochemistry

Volumn 45, Issue 5, 2006, Pages 1435-1441

  Solt, Ken ^a   Johansson, Jonas S ^b   Raines, Douglas E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETICS; BIOCHEMISTRY; CONFORMATIONS; FLUORESCENCE; MOLECULAR DYNAMICS; REACTION KINETICS;

CONFORMATIONAL TRANSITIONS; FLUORESCENCE SPECTROSCOPY; LIGAND-GATED ION CHANNELS (LGIC); SPECTROFLUORIMETERS;

PROTEINS;

CYCLOPROPANE; CYSTEINE; DESFLURANE; HALOTHANE; INHALATION ANESTHETIC AGENT; ION CHANNEL; ISOFLURANE; SEVOFLURANE; TRYPTOPHAN;

ALPHA HELIX; ARTICLE; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANESTHETICS, INHALATION; CYSTEINE; HALOTHANE; ION CHANNEL GATING; ION CHANNELS; KINETICS; LIGANDS; METHYL ETHERS; MODELS, CHEMICAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE;

EID: 32244438024     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052206o     Document Type: Article

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