-
1
-
-
34249982884
-
A receptor-channel kinetic behavior
-
DOI 10.1111/j.1460-9568.2007.05530.x
-
Barberis A, Mozrzymas JW, Ortinski PI, and Vicini S (2007) Desensitization and binding properties determine distinct α1β2γ 2 and α3β2γ2 GABAA receptorchannel kinetic behavior. Eur J Neurosci 25:2726-2740. (Pubitemid 46888845)
-
(2007)
European Journal of Neuroscience
, vol.25
, Issue.9
, pp. 2726-2740
-
-
Barberis, A.1
Mozrzymas, J.W.2
Ortinski, P.I.3
Vicini, S.4
-
2
-
-
0037195864
-
A receptors: Insight into the absolute arrangement
-
DOI 10.1074/jbc.M207663200
-
Baumann SW, Baur R, and Sigel E (2002) Forced subunit assembly in α1β2γ2 GABAA receptors. Insight into the absolute arrangement. J Biol Chem 277:46020-46025. (Pubitemid 35417587)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.48
, pp. 46020-46025
-
-
Baumann, S.W.1
Baur, R.2
Sigel, E.3
-
3
-
-
0027938035
-
Distribution, prevalence, and drug binding profile of γ-aminobutyric acid type A receptor subtypes differing in the β-subunit variant
-
Benke D, Fritschy JM, Trzeciak A, Bannwarth W, and Mohler H (1994) Distribution, prevalence, and drug binding profile of γ-aminobutyric acid type A receptor subtypes differing in the β-subunit variant. J Biol Chem 269:27100-27107. (Pubitemid 24332916)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.43
, pp. 27100-27107
-
-
Benke, D.1
Fritschy, J.-M.2
Trzeciak, A.3
Bannwarth, W.4
Mohler, H.5
-
4
-
-
0036794311
-
A receptor desensitization: Structural determinants and possible relevance for synaptic function
-
A receptor desensitization: structural determinants and possible relevance for synaptic function. J Physiol 544:3-18.
-
(2002)
J Physiol
, vol.544
, pp. 3-18
-
-
Bianchi, M.T.1
Macdonald, R.L.2
-
6
-
-
0028268676
-
A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygens
-
Borders CL Jr, Broadwater JA, Bekeny PA, Salmon JE, Lee AS, Eldridge AM, and Pett VB (1994) A structural role for arginine in proteins: multiple hydrogen bonds to backbone carbonyl oxygens. Protein Sci 3:541-548. (Pubitemid 24136359)
-
(1994)
Protein Science
, vol.3
, Issue.4
, pp. 541-548
-
-
Borders Jr., C.L.1
Broadwater, J.A.2
Bekeny, P.A.3
Salmon, J.E.4
Lee, A.S.5
Eldridge, A.M.6
Pett, V.B.7
-
8
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
DOI 10.1038/35077011
-
Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, and Sixma TK (2001) Crystal structure of an ACh-binding protein reveals the ligandbinding domain of nicotinic receptors. Nature 411:269-276. (Pubitemid 32467026)
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der, O.J.5
Smit, A.B.6
Sixma, T.K.7
-
10
-
-
0032199006
-
Binding, gating, affinity and efficacy: The interpretation of structure-activity relationships for agonists and of the effects of mutating receptors
-
Colquhoun D (1998) Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125:924-947.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 924-947
-
-
Colquhoun, D.1
-
11
-
-
0000410893
-
The principles of the stochastic interpretation of ion-channel mechanisms
-
Sakmann B and Neher E eds Plenum, New York
-
Colquhoun D and Hawkes AG (1995a) The principles of the stochastic interpretation of ion-channel mechanisms, in Single-Channel Recording (Sakmann B and Neher E eds) pp 397-482, Plenum, New York.
-
(1995)
Single-Channel Recording
, pp. 397-482
-
-
Colquhoun, D.1
Hawkes, A.G.2
-
12
-
-
0000410893
-
A Q-matrix cookbook. How to write only one program to calculate the single-channel and macroscopic predictions for any kinetic mechanism
-
Sakmann B and Neher E eds Plenum, New York
-
Colquhoun D and Hawkes AG (1995b) A Q-matrix cookbook. How to write only one program to calculate the single-channel and macroscopic predictions for any kinetic mechanism, in Single-Channel Recording (Sakmann B and Neher E eds) pp 589-633, Plenum, New York.
-
(1995)
Single-Channel Recording
, pp. 589-633
-
-
Colquhoun, D.1
Hawkes, A.G.2
-
14
-
-
58149093958
-
An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating
-
Gleitsman KR, Kedrowski SM, Lester HA, and Dougherty DA (2008) An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating. J Biol Chem 283:35638-35643.
-
(2008)
J Biol Chem
, vol.283
, pp. 35638-35643
-
-
Gleitsman, K.R.1
Kedrowski, S.M.2
Lester, H.A.3
Dougherty, D.A.4
-
16
-
-
0030322783
-
Double-mutant cycles: A powerful tool for analyzing protein structure and function
-
Horovitz A (1996) Double-mutant cycles: a powerful tool for analyzing protein structure and function. Fold Des 1:R121-R126.
-
(1996)
Fold Des
, vol.1
-
-
Horovitz, A.1
-
17
-
-
0025663105
-
Strength and co-operativity of contributions of surface salt bridges to protein stability
-
Horovitz A, Serrano L, Avron B, Bycroft M, and Fersht AR (1990) Strength and co-operativity of contributions of surface salt bridges to protein stability. J Mol Biol 216:1031-1044.
-
(1990)
J Mol Biol
, vol.216
, pp. 1031-1044
-
-
Horovitz, A.1
Serrano, L.2
Avron, B.3
Bycroft, M.4
Fersht, A.R.5
-
18
-
-
0034753212
-
A receptor agonists from antagonists
-
Jones MV, Jonas P, Sahara Y, and Westbrook GL (2001) Microscopic kinetics and energetics distinguish GABAA receptor agonists from antagonists. Biophys J 81:2660-2670. (Pubitemid 33020053)
-
(2001)
Biophysical Journal
, vol.81
, Issue.5
, pp. 2660-2670
-
-
Jones, M.V.1
Jonas, P.2
Sahara, Y.3
Westbrook, G.L.4
-
20
-
-
0029112106
-
A channel responses to brief agonist pulses
-
A channel responses to brief agonist pulses. Neuron 15:181-191.
-
(1995)
Neuron
, vol.15
, pp. 181-191
-
-
Jones, M.V.1
Westbrook, G.L.2
-
21
-
-
0037448581
-
A receptor
-
DOI 10.1038/nature01280
-
Kash TL, Jenkins A, Kelley JC, Trudell JR, and Harrison NL (2003) Coupling of agonist binding to channel gating in the GABAA receptor. Nature 421:272-275. (Pubitemid 36139131)
-
(2003)
Nature
, vol.421
, Issue.6920
, pp. 272-275
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
23
-
-
33846455076
-
A receptor
-
DOI 10.1124/mol.106.028662
-
Kloda JH and Czajkowski C (2007) Agonist-, antagonist-, and benzodiazepineinduced structural changes in the α1 Met113-Leu132 region of the GABAA receptor. Mol Pharmacol 71:483-493. (Pubitemid 46147915)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.2
, pp. 483-493
-
-
Kloda, J.H.1
Czajkowski, C.2
-
24
-
-
70349967621
-
Modeling neuronal nicotinic and GABA receptors: Important interface salt-links and protein dynamics
-
Law RJ and Lightstone FC (2009) Modeling neuronal nicotinic and GABA receptors: important interface salt-links and protein dynamics. Biophys J 97:1586-1594.
-
(2009)
Biophys J
, vol.97
, pp. 1586-1594
-
-
Law, R.J.1
Lightstone, F.C.2
-
25
-
-
0024474066
-
Kinetic properties of the GABA(A) receptor main conductance state of mouse spinal cord neurones in culture
-
Macdonald RL, Rogers CJ, and Twyman RE (1989) Kinetic properties of the GABAA receptor main conductance state of mouse spinal neurones in culture. J Physiol 410:479-499. (Pubitemid 19075156)
-
(1989)
Journal of Physiology
, vol.410
, pp. 479-499
-
-
McDonald, R.L.1
Rogers, C.J.2
Twyman, R.E.3
-
26
-
-
0037432563
-
Contribution of surface salt bridges to protein stability: Guidelines for protein engineering
-
DOI 10.1016/S0022-2836(03)00233-X
-
Makhatadze GI, Loladze VV, Ermolenko DN, Chen X, and Thomas ST (2003) Contribution of surface salt bridges to protein stability: guidelines for protein engineering. J Mol Biol 327:1135-1148. (Pubitemid 36363718)
-
(2003)
Journal of Molecular Biology
, vol.327
, Issue.5
, pp. 1135-1148
-
-
Makhatadze, G.I.1
Loladze, V.V.2
Ermolenko, D.N.3
Chen, X.4
Thomas, S.T.5
-
27
-
-
0029670123
-
Which GABAA-receptor subtypes really occur in the brain?
-
McKernan RM and Whiting PJ (1996) Which GABAA-receptor subtypes really occur in the brain? Trends Neurosci 19:139-143.
-
(1996)
Trends Neurosci
, vol.19
, pp. 139-143
-
-
McKernan, R.M.1
Whiting, P.J.2
-
28
-
-
33745015539
-
A receptor
-
DOI 10.1021/bi060222v
-
Muroi Y, Czajkowski C, and Jackson MB (2006) Local and global ligand-induced changes in the structure of the GABAA receptor. Biochemistry 45:7013-7022. (Pubitemid 43877390)
-
(2006)
Biochemistry
, vol.45
, Issue.23
, pp. 7013-7022
-
-
Muroi, Y.1
Czajkowski, C.2
Jackson, M.B.3
-
29
-
-
10644270878
-
2 subunit produces a spontaneously open channel: A trigger for channel activation
-
DOI 10.1523/JNEUROSCI.3746-04.2004
-
Newell JG, McDevitt RA, and Czajkowski C (2004) Mutation of glutamate 155 of the GABAA receptor β2 subunit produces a spontaneously open channel: a trigger for channel activation. J Neurosci 24:11226-11235. (Pubitemid 39658257)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.50
, pp. 11226-11235
-
-
Newell, J.G.1
McDevitt, R.A.2
Czajkowski, C.3
-
30
-
-
17844374081
-
A receptor examined using Brownian dynamics
-
DOI 10.1529/biophysj.104.051664
-
O'Mara M, Cromer B, Parker M, and Chung SH (2005) Homology model of the GABAA receptor examined using Brownian dynamics. Biophys J 88:3286-3299. (Pubitemid 40586580)
-
(2005)
Biophysical Journal
, vol.88
, Issue.5
, pp. 3286-3299
-
-
O'Mara, M.1
Cromer, B.2
Parker, M.3
Chung, S.-H.4
-
32
-
-
34548485996
-
C receptors
-
DOI 10.1074/jbc.M702524200
-
Price KL, Millen KS, and Lummis SC (2007) Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors. J Biol Chem 282:25623-25630. (Pubitemid 47372843)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.35
, pp. 25623-25630
-
-
Price, K.L.1
Millen, K.S.2
Lummis, S.C.R.3
-
33
-
-
0019229699
-
The variance of sodium current fluctuations at the node of Ranvier
-
Sigworth FJ (1980) The variance of sodium current fluctuations at the node of Ranvier. J Physiol 307:97-129.
-
(1980)
J Physiol
, vol.307
, pp. 97-129
-
-
Sigworth, F.J.1
-
35
-
-
77952377218
-
Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation
-
Todorovic J, Welsh BT, Bertaccini EJ, Trudell JR, and Mihic SJ (2010) Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation. Proc Natl Acad Sci USA 107:7987-7992.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7987-7992
-
-
Todorovic, J.1
Welsh, B.T.2
Bertaccini, E.J.3
Trudell, J.R.4
Mihic, S.J.5
-
36
-
-
0035141668
-
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation
-
Wagner DA and Czajkowski C (2001) Structure and dynamics of the GABA binding pocket: a narrowing cleft that constricts during activation. J Neurosci 21:67-74. (Pubitemid 32098727)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.1
, pp. 67-74
-
-
Wagner, D.A.1
Czajkowski, C.2
-
37
-
-
1642282626
-
A Receptor
-
DOI 10.1523/JNEUROSCI.4316-03.2004
-
Wagner DA, Czajkowski C, and Jones MV (2004) An arginine involved in GABA binding and unbinding but not gating of the GABAA receptor. J Neurosci 24:2733-2741. (Pubitemid 38380950)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.11
, pp. 2733-2741
-
-
Wagner, D.A.1
Czajkowski, C.2
Jones, M.V.3
-
38
-
-
0033516983
-
1, subunit is essential for GABA binding and chloride ion current gating
-
Westh-Hansen SE, Witt MR, Dekermendjian K, Liljefors T, Rasmussen PB, and Nielsen M (1999) Arginine residue 120 of the human GABAA receptor α1 subunit is essential for GABA binding and chloride ion current gating. Neuroreport 10:2417-2421. (Pubitemid 29367949)
-
(1999)
NeuroReport
, vol.10
, Issue.11
, pp. 2417-2421
-
-
Westh-Hansen, S.E.1
Witt, M.R.2
Dekermendjian, K.3
Liljefors, T.4
Rasmussen, P.B.5
Nielsen, M.6
|