Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases

Journal of Medicinal Chemistry

Volumn 54, Issue 6, 2011, Pages 1682-1692

  Davis, Rohan A ^a   Hofmann, Andreas ^a   Osman, Asiah ^a   Hall, Rebecca A ^c   Mühlschlegel, Fritz A ^c,d   Vullo, Daniela ^b   Innocenti, Alessio ^b   Supuran, Claudiu T ^b   Poulsen, Sally Ann ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF KENT   (United Kingdom)

^d EAST KENT HOSPITALS UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; DIHYDROGUAIARETIC ACID; ENDIANDRIN A; ENDIANDRIN B; NATURAL PRODUCT; PHENOL; PHENOL DERIVATIVE; POLYANDROCARPAMINE A; POLYANDROCARPAMINE B; SULFAMIC ACID; SULFANILAMIDE; TOPIRAMATE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE; XYLARIAMIDE A; ZONISAMIDE;

ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG ISOLATION; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BIOLOGICAL PRODUCTS; CANDIDA ALBICANS; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYTIC DOMAIN; CRYPTOCOCCUS NEOFORMANS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PHENOLS; PROTEIN BINDING; SMALL MOLECULE LIBRARIES;

EID: 79952786687     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1013242     Document Type: Article

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