메뉴 건너뛰기




Volumn 18, Issue 7, 2011, Pages 1079-1084

In vitro models for the study of non-alcoholic fatty liver disease

Author keywords

Biological models; Biomedical research; Fatty acids; Fatty liver

Indexed keywords

FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 79952776936     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986711794940842     Document Type: Article
Times cited : (45)

References (64)
  • 3
    • 63349086412 scopus 로고    scopus 로고
    • Ethnic differences in hepatic steatosis: An insulin resistance paradox?
    • Guerrero, R.; Vega, G.L.; Grundy, S.M.; Browning, J.D. Ethnic differences in hepatic steatosis: An insulin resistance paradox? Hepatology (Baltimore, Md., 2009, 49(3), 791-801.
    • (2009) Hepatology (Baltimore, Md.) , vol.49 , Issue.3 , pp. 791-801
    • Guerrero, R.1    Vega, G.L.2    Grundy, S.M.3    Browning, J.D.4
  • 4
    • 33846900939 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: Further expression of the metabolic syndrome
    • DOI 10.1111/j.1440-1746.2007.04824.x
    • Tarantino, G.; Saldalamacchia, G.; Conca, P.; Arena, A. Non-alcoholic fatty liver disease: Further expression of the metabolic syndrome. J. Gastroenterol. Hepatol., 2007, 22(3), 293-303. (Pubitemid 46238755)
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , Issue.3 , pp. 293-303
    • Tarantino, G.1    Saldalamacchia, G.2    Conca, P.3    Arena, A.4
  • 6
    • 75349091707 scopus 로고    scopus 로고
    • Pediatric non-alcoholic fatty liver disease: Preventive and therapeutic value of lifestyle intervention
    • Nobili, V.; Alisi, A.; Raponi, M. Pediatric non-alcoholic fatty liver disease: Preventive and therapeutic value of lifestyle intervention. World J. Gastroenterol., 2009, 15(48), 6017-6022.
    • (2009) World J. Gastroenterol. , vol.15 , Issue.48 , pp. 6017-6022
    • Nobili, V.1    Alisi, A.2    Raponi, M.3
  • 7
    • 56649106415 scopus 로고    scopus 로고
    • Effects of weight loss on nonalcoholic fatty liver disease
    • Rafiq, N.; Younossi, Z.M. Effects of weight loss on nonalcoholic fatty liver disease. Semin. Liver Dis., 2008, 28(4), 427-433.
    • (2008) Semin. Liver Dis. , vol.28 , Issue.4 , pp. 427-433
    • Rafiq, N.1    Younossi, Z.M.2
  • 8
    • 56549117448 scopus 로고    scopus 로고
    • Animal models of NASH: Getting both pathology and metabolic context right
    • Larter, C.Z.; Yeh, M.M. Animal models of NASH: Getting both pathology and metabolic context right. J. Gastroenterol. Hepatol., 2008, 23(11), 1635-1648.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , Issue.11 , pp. 1635-1648
    • Larter, C.Z.1    Yeh, M.M.2
  • 9
    • 4644341747 scopus 로고    scopus 로고
    • Human hepatocytes in primary culture: The choice to investigate drug metabolism in man
    • DOI 10.2174/1389200043335414
    • Gomez-Lechon, M.J.; Donato, M.T.; Castell, J.V.; Jover, R. Human hepatocytes in primary culture: The choice to investigate drug metabolism in man. Curr. Drug Metab., 2004, 5(5), 443-462. (Pubitemid 39276606)
    • (2004) Current Drug Metabolism , vol.5 , Issue.5 , pp. 443-462
    • Gomez-Lechon, M.J.1    Donato, M.T.2    Castell, J.V.3    Jover, R.4
  • 10
    • 38849184046 scopus 로고    scopus 로고
    • Cell lines: A tool for in vitro drug metabolism studies
    • DOI 10.2174/138920008783331086
    • Donato, M.T.; Lahoz, A.; Castell, J.V.; Gomez-Lechon, M.J. Cell lines: A tool for in. vitro drug metabolism studies. Curr. Drug Metab., 2008, 9(1), 1-11 (Pubitemid 351201665)
    • (2008) Current Drug Metabolism , vol.9 , Issue.1 , pp. 1-11
    • Donato, M.T.1    Lahoz, A.2    Castell, J.V.3    Gomez-Lechon, M.J.4
  • 11
    • 58949088510 scopus 로고    scopus 로고
    • Natural history: The importance of viral load, liver damage and HCC
    • Wursthorn, K.; Manns, M.P.; Wedemeyer, H. Natural history: The importance of viral load, liver damage and HCC. Best Pract. Res. Clin. Gastroentrol., 2008, 22(6), 1063-1079.
    • (2008) Best Pract. Res. Clin. Gastroentrol. , vol.22 , Issue.6 , pp. 1063-1079
    • Wursthorn, K.1    Manns, M.P.2    Wedemeyer, H.3
  • 12
    • 13444284018 scopus 로고    scopus 로고
    • New technologies and screening strategies for hepatotoxicity: Use of in vitro models
    • DOI 10.1080/01926230590522284
    • Dambach, D.M.; Andrews, B.A.; Moulin, F. New technologies and screening strategies for hepatotoxicity: Use of in vitro models. Toxicol. Pathol., 2005, 33(1), 17-26. (Pubitemid 40216800)
    • (2005) Toxicologic Pathology , vol.33 , Issue.1 , pp. 17-26
    • Dambach, D.M.1    Andrews, B.A.2    Moulin, F.3
  • 14
    • 34249930707 scopus 로고    scopus 로고
    • Establishment of immortalized rat Kupffer cell lines
    • DOI 10.1016/j.cyto.2007.03.003, PII S1043466607000403
    • Peng, Y.; Murr, M.M. Establishment of immortalized rat Kupffer cell lines. Cytokine, 2007, 37(3), 185-191. (Pubitemid 46880387)
    • (2007) Cytokine , vol.37 , Issue.3 , pp. 185-191
    • Peng, Y.1    Murr, M.M.2
  • 15
    • 67449097127 scopus 로고    scopus 로고
    • Maintaining hepatocyte differentiation in. vitro through co-culture with hepatic stellate cells
    • Krause, P.; Saghatolislam, F.; Koenig, S.; Unthan-Fechner, K.; Probst, I. Maintaining hepatocyte differentiation in. vitro through co-culture with hepatic stellate cells. In Vitro Cell. Dev. Biol., 2009, 45(5-6), 205-212.
    • (2009) Vitro Cell. Dev. Biol. , vol.45 , Issue.5-6 , pp. 205-212
    • Krause, P.1    Saghatolislam, F.2    Koenig, S.3    Unthan-Fechner, K.4    Probst, I.5
  • 16
    • 33644961249 scopus 로고    scopus 로고
    • The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro
    • Thomas, R.J.; Bhandari, R.; Barrett, D.A.; Bennett, A.J.; Fry, J.R.; Powe, D.; Thomson, B.J.; Shakesheff, K.M. The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro. Cells Tissues Org., 2005, 181(2), 67-79.
    • (2005) Cells Tissues Org. , vol.181 , Issue.2 , pp. 67-79
    • Thomas, R.J.1    Bhandari, R.2    Barrett, D.A.3    Bennett, A.J.4    Fry, J.R.5    Powe, D.6    Thomson, B.J.7    Shakesheff, K.M.8
  • 18
    • 33746045298 scopus 로고    scopus 로고
    • Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu
    • DOI 10.1016/j.cbi.2006.05.006, PII S0009279706001128
    • van de Bovenkamp, M.; Groothuis, G.M.; Meijer, D.K.; Slooff, M.J.; Olinga, P. Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu. Chemico-Biol. Interact., 2006, 162(1), 62-69. (Pubitemid 44080167)
    • (2006) Chemico-Biological Interactions , vol.162 , Issue.1 , pp. 62-69
    • Van De Bovenkamp, M.1    Groothuis, G.M.M.2    Meijer, D.K.F.3    Slooff, M.J.H.4    Olinga, P.5
  • 19
    • 0016828072 scopus 로고
    • Fatty liver induced by tetracycline in the rat. Dose-response relationships and effect of sex
    • Breen, K.J.; Schenker, S.; Heimberg, M. Fatty liver induced by tetracycline in the rat. Dose-response relationships and effect of sex. Gastroenterology, 1975, 69(3), 714-723.
    • (1975) Gastroenterology , vol.69 , Issue.3 , pp. 714-723
    • Breen, K.J.1    Schenker, S.2    Heimberg, M.3
  • 20
    • 0024549203 scopus 로고
    • Investigation into the mechanism of tetracycline-induced steatosis: Study in isolated hepatocytes
    • DOI 10.1016/0041-008X(89)90252-4
    • Deboyser, D.; Goethals, F.; Krack, G.; Roberfroid, M. Investigation into the mechanism of tetracycline-induced steatosis: Study in isolated hepatocytes. Toxicol. Appl. Pharmacol., 1989, 97(3), 473-479. (Pubitemid 19094963)
    • (1989) Toxicology and Applied Pharmacology , vol.97 , Issue.3 , pp. 473-479
    • Deboyser, D.1    Goethals, F.2    Krack, G.3    Roberfroid, M.4
  • 21
    • 85033532182 scopus 로고    scopus 로고
    • Tetracycline-induced steatosis in primary canine hepatocyte cultures
    • Amacher, D.E.; Martin, B.A. Tetracycline-induced steatosis in primary canine hepatocyte cultures. Fundam. Appl. Toxicol., 1997, 40(2), 256-263.
    • (1997) Fundam. Appl. Toxicol. , vol.40 , Issue.2 , pp. 256-263
    • Amacher, D.E.1    Martin, B.A.2
  • 22
    • 30944455145 scopus 로고    scopus 로고
    • Insulin resistance: A metabolic pathway to chronic liver disease
    • DOI 10.1002/hep.20920
    • Bugianesi, E.; McCullough, A.J.; Marchesini, G. Insulin resistance: A metabolic pathway to chronic liver disease. Hepatology, 2005, 42(5), 987-1000. (Pubitemid 43112663)
    • (2005) Hepatology , vol.42 , Issue.5 , pp. 987-1000
    • Bugianesi, E.1    McCullough, A.J.2    Marchesini, G.3
  • 23
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic Fatty Liver Disease: Cytokine-Adipokine Interplay and Regulation of Insulin Resistance
    • DOI 10.1053/j.gastro.2006.05.054, PII S0016508506012078
    • Tilg, H.; Hotamisligil, G.S. Nonalcoholic fatty liver disease: Cytokineadipokine interplay and regulation of insulin resistance. Gastroenterology, 2006, 131(3), 934-945. (Pubitemid 44307061)
    • (2006) Gastroenterology , vol.131 , Issue.3 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 24
    • 33845663688 scopus 로고    scopus 로고
    • High glucose alone, as well as in combination with proinflammatory cytokines, stimulates nuclear factor kappa-B-mediated transcription in hepatocytes in vitro
    • DOI 10.1016/j.jdiacomp.2006.02.001, PII S1056872706000110
    • Iwasaki, Y.; Kambayashi, M.; Asai, M.; Yoshida, M.; Nigawara, T.; Hashimoto, K. High glucose alone, as well as in combination with proinflammatory cytokines, stimulates nuclear factor kappa-B-mediated transcription in hepatocytes in vitro. J. Diabetes Complicat., 2007, 21(1), 56-62. (Pubitemid 44960844)
    • (2007) Journal of Diabetes and its Complications , vol.21 , Issue.1 , pp. 56-62
    • Iwasaki, Y.1    Kambayashi, M.2    Asai, M.3    Yoshida, M.4    Nigawara, T.5    Hashimoto, K.6
  • 25
    • 55849106577 scopus 로고    scopus 로고
    • Role of body fat distribution and the metabolic complications of obesity
    • Jensen, M.D. Role of body fat distribution and the metabolic complications of obesity. J. Clin. Endocrinol. Metab., 2008, 93(11 Suppl 1), S57-63.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.11 SUPPL. 1
    • Jensen, M.D.1
  • 27
    • 67649653963 scopus 로고    scopus 로고
    • Age-associated increase in cytokine production during systemic inflammation: Adipose tissue as a major source of IL-6
    • Starr, M.E.; Evers, B.M.; Saito, H. Age-associated increase in cytokine production during systemic inflammation: Adipose tissue as a major source of IL-6. J. Gerontol., 2009, 64(7), 723-730.
    • (2009) J. Gerontol. , vol.64 , Issue.7 , pp. 723-730
    • Starr, M.E.1    Evers, B.M.2    Saito, H.3
  • 28
    • 67650360218 scopus 로고    scopus 로고
    • Obesity provides a permissive milieu in inflammation-associated carcinogenesis: Analysis of insulin and IGF pathways
    • Nunez, N.P.; Hursting, S.D.; Yakar, S.; Fowler, D.; Vinson, C. Obesity provides a permissive milieu in inflammation-associated carcinogenesis: Analysis of insulin and IGF pathways. Methods Mol. Biol. (Clifton, N.J.), 2009, 512, 29-37.
    • (2009) Methods Mol. Biol. (Clifton, N.J.) , vol.512 , pp. 29-37
    • Nunez, N.P.1    Hursting, S.D.2    Yakar, S.3    Fowler, D.4    Vinson, C.5
  • 29
    • 67651216391 scopus 로고    scopus 로고
    • Adipokines as regulators of muscle metabolism and insulin sensitivity
    • Dyck, D.J. Adipokines as regulators of muscle metabolism and insulin sensitivity. Appl. Physiol. Nutr. Metab., 2009, 34(3), 396-402.
    • (2009) Appl. Physiol. Nutr. Metab. , vol.34 , Issue.3 , pp. 396-402
    • Dyck, D.J.1
  • 30
  • 31
    • 55949114663 scopus 로고    scopus 로고
    • Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism
    • Girard, J.; Lafontan, M. Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism. Diabetes Metab., 2008, 34(5), 439-445.
    • (2008) Diabetes Metab. , vol.34 , Issue.5 , pp. 439-445
    • Girard, J.1    Lafontan, M.2
  • 32
    • 38449101948 scopus 로고    scopus 로고
    • Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line
    • DOI 10.1002/bit.21568
    • Srivastava, S.; Chan, C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnol. Bioeng., 2008, 99(2), 399-410. (Pubitemid 351158288)
    • (2008) Biotechnology and Bioengineering , vol.99 , Issue.2 , pp. 399-410
    • Srivastava, S.1    Chan, C.2
  • 33
    • 58149473989 scopus 로고    scopus 로고
    • Nutritional lipidinduced oxidative stress leads to mitochondrial dysfunction followed by necrotic death in FaO hepatocytes
    • Tirosh, O.; Ilan, E.; Anavi, S.; Ramadori, G.; Madar, Z. Nutritional lipidinduced oxidative stress leads to mitochondrial dysfunction followed by necrotic death in FaO hepatocytes. Nutrition (Burbank, Los Angeles County, Calif), 2009, 25(2), 200-208.
    • (2009) Nutrition (Burbank, Los Angeles County, Calif) , vol.25 , Issue.2 , pp. 200-208
    • Tirosh, O.1    Ilan, E.2    Anavi, S.3    Ramadori, G.4    Madar, Z.5
  • 35
    • 33744948514 scopus 로고    scopus 로고
    • Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis
    • DOI 10.1074/jbc.M510660200
    • Malhi, H.; Bronk, S.F.; Werneburg, N.W.; Gores, G.J. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. J. Biol. Chem., 2006, 281(17), 12093-12101. (Pubitemid 43855473)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.17 , pp. 12093-12101
    • Malhi, H.1    Bronk, S.F.2    Werneburg, N.W.3    Gores, G.J.4
  • 36
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two hits?
    • Day, C.P.; James, O.F. Steatohepatitis: A tale of two "hits"? Gastroenterology, 1998, 114(4), 842-845.
    • (1998) Gastroenterology , vol.114 , Issue.4 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 38
    • 34548746833 scopus 로고    scopus 로고
    • Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes
    • DOI 10.1002/hep.21752
    • Joshi-Barve, S.; Barve, S.S.; Amancherla, K.; Gobejishvili, L.; Hill, D.; Cave, M.; Hote, P.; McClain, C.J. Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes. Hepatology (Baltimore, Md.), 2007, 46(3), 823-830. (Pubitemid 47436129)
    • (2007) Hepatology , vol.46 , Issue.3 , pp. 823-830
    • Joshi-Barve, S.1    Barve, S.S.2    Amancherla, K.3    Gobejishvili, L.4    Hill, D.5    Cave, M.6    Hote, P.7    McClain, C.J.8
  • 39
    • 63549141896 scopus 로고    scopus 로고
    • Development of an in vitro cell culture model of hepatic steatosis using hepatocyte-derived reporter cells
    • Janorkar, A.V.; King, K.R.; Megeed, Z.; Yarmush, M.L. Development of an in vitro cell culture model of hepatic steatosis using hepatocyte-derived reporter cells. Biotechnol. Bioeng., 2009, 102(5), 1466-1474.
    • (2009) Biotechnol. Bioeng. , vol.102 , Issue.5 , pp. 1466-1474
    • Janorkar, A.V.1    King, K.R.2    Megeed, Z.3    Yarmush, M.L.4
  • 40
    • 79952781211 scopus 로고    scopus 로고
    • Increased expression of IL-6 and IL-8 mrna in human immortalized hepatocytes after fat overload
    • Chavez-Tapia, N.; Rosso, N.; Tiribelli, C. Increased expression of IL-6 and IL-8 mrna in human immortalized hepatocytes after fat overload. J. Hepatol., 2009, 698.
    • (2009) J. Hepatol. , vol.698
    • Chavez-Tapia, N.1    Rosso, N.2    Tiribelli, C.3
  • 41
    • 48649110854 scopus 로고    scopus 로고
    • The role of fatty acids in the development and progression of nonalcoholic fatty liver disease
    • Gentile, C.L.; Pagliassotti, M.J. The role of fatty acids in the development and progression of nonalcoholic fatty liver disease. J. Nutr. Biochem., 2008, 19(9), 567-576.
    • (2008) J. Nutr. Biochem. , vol.19 , Issue.9 , pp. 567-576
    • Gentile, C.L.1    Pagliassotti, M.J.2
  • 44
    • 17744410109 scopus 로고    scopus 로고
    • Insights into binding of fatty acids by fatty acid binding proteins
    • DOI 10.1023/A:1020502624234
    • Hanhoff, T.; Lucke, C.; Spener, F. Insights into binding of fatty acids by fatty acid binding proteins. Mol. Cell. Biochem., 2002, 239(1-2), 45-54. (Pubitemid 35385794)
    • (2002) Molecular and Cellular Biochemistry , vol.239 , Issue.1-2 , pp. 45-54
    • Hanhoff, T.1    Lucke, C.2    Spener, F.3
  • 45
    • 1442357806 scopus 로고    scopus 로고
    • Enterocyte fatty acid uptake and intestinal fatty acid-binding protein
    • DOI 10.1042/BST0320075
    • Tso, P.; Nauli, A.; Lo, C.M. Enterocyte fatty acid uptake and intestinal fatty acid-binding protein. Biochem. Soc. Trans., 2004, 32(Pt 1), 75-78. (Pubitemid 38283017)
    • (2004) Biochemical Society Transactions , vol.32 , Issue.1 , pp. 75-78
    • Tso, P.1    Nauli, A.2    Lo, C.-M.3
  • 46
    • 0027275837 scopus 로고
    • Interactions of long-chain fatty acids and albumin: Determination of free fatty acid levels using the fluorescent probe ADIFAB
    • Richieri, G.V.; Anel, A.; Kleinfeld, A.M. Interactions of long-chain fatty acids and albumin: Determination of free fatty acid levels using the fluorescent probe ADIFAB. Biochemistry, 1993, 32(29), 7574-7580. (Pubitemid 23232334)
    • (1993) Biochemistry , vol.32 , Issue.29 , pp. 7574-7580
    • Richieri, G.V.1    Anel, A.2    Kleinfeld, A.M.3
  • 47
    • 0032030819 scopus 로고    scopus 로고
    • Reduction in hepatic cytochrome P-450 is correlated to the degree of liver fat content in animal models of steatosis in the absence of inflammation
    • DOI 10.1016/S0168-8278(98)80314-0
    • Leclercq, I.; Horsmans, Y.; Desager, J.P.; Delzenne, N.; Geubel, A.P. Reduction in hepatic cytochrome P-450 is correlated to the degree of liver fat content in animal models of steatosis in the absence of inflammation. J. Hepatol., 1998, 28(3), 410-416. (Pubitemid 28133544)
    • (1998) Journal of Hepatology , vol.28 , Issue.3 , pp. 410-416
    • Leclercq, I.1    Horsmans, Y.2    Desager, J.-P.3    Delzenne, N.4    Geubel, A.-P.5
  • 48
    • 0037369729 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis
    • DOI 10.1053/jhep.2003.50095
    • Chalasani, N.; Gorski, J.C.; Asghar, M.S.; Asghar, A.; Foresman, B.; Hall, S.D.; Crabb, D.W. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis. Hepatology, 2003, 37(3), 544-550. (Pubitemid 36258775)
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 544-550
    • Chalasani, N.1    Christopher Gorski, J.2    Asghar, M.S.3    Asghar, A.4    Foresman, B.5    Hall, S.D.6    Crabb, D.W.7
  • 49
    • 0031962151 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
    • DOI 10.1002/hep.510270121
    • Weltman, M.D.; Farrell, G.C.; Hall, P.; Ingelman-Sundberg, M.; Liddle, C. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. Hepatology, 1998, 27(1), 128-133. (Pubitemid 28041545)
    • (1998) Hepatology , vol.27 , Issue.1 , pp. 128-133
    • Weltman, M.D.1    Farrell, G.C.2    Hall, P.3    Ingelman-Sundberg, M.4    Liddle, C.5
  • 50
    • 0030034099 scopus 로고    scopus 로고
    • Expression of genes coding for antioxidant enzymes and heat shock proteins is altered in primary cultures of rat hepatocytes
    • DOI 10.1002/(SICI)1097-4652(199602)166:2<453::AID-JCP24>3.0.CO;2-A
    • Van Remmen, H.; Williams, M.D.; Heydari, A.R.; Takahashi, R.; Chung, H.Y.; Yu, B.P.; Richardson, A. Expression of genes coding for antioxidant enzymes and heat shock proteins is altered in primary cultures of rat hepatocytes. J. Cell. Physiol., 1996, 166(2), 453-460. (Pubitemid 26042423)
    • (1996) Journal of Cellular Physiology , vol.166 , Issue.2 , pp. 453-460
    • Van Remmen, H.1    Williams, M.D.2    Heydari, A.R.3    Takahashi, R.4    Chung, H.Y.5    Yu, B.P.6    Richardson, A.7
  • 51
    • 0036301269 scopus 로고    scopus 로고
    • Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells
    • DOI 10.1080/00498250210128675
    • Rodriguez-Antona, C.; Donato, M.T.; Boobis, A.; Edwards, R.J.; Watts, P.S.; Castell, J.V.; Gomez-Lechon, M.J. Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: Molecular mechanisms that determine lower expression in cultured cells. Xenobiotica, 2002, 32(6), 505-520. (Pubitemid 34743622)
    • (2002) Xenobiotica , vol.32 , Issue.6 , pp. 505-520
    • Rodriguez-Antona, C.1    Donato, M.T.2    Boobis, A.3    Edwards, R.J.4    Watts, P.S.5    Castell, J.V.6    Gomez-Lechon, M.-J.7
  • 55
    • 65749090011 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate, a NF-kappaB inhibitor, upregulates MMP-1 and MMP-13 in IL-1beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes
    • Kim, K.S.; Oh da, H.; Choi, H.M.; Bang, J.S.; Ryu, C.J.; Kim, J.H.; Yoo, M.C.; Yang, H.I. Pyrrolidine dithiocarbamate, a NF-kappaB inhibitor, upregulates MMP-1 and MMP-13 in IL-1beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes. Eur. J. Pharmacol., 2009, 613(1-3), 167-175.
    • (2009) Eur. J. Pharmacol. , vol.613 , Issue.1-3 , pp. 167-175
    • Kim, K.S.1    Oh Da, H.2    Choi, H.M.3    Bang, J.S.4    Ryu, C.J.5    Kim, J.H.6    Yoo, M.C.7    Yang, H.I.8
  • 56
    • 34548124842 scopus 로고    scopus 로고
    • Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes
    • DOI 10.1016/j.febslet.2007.07.076, PII S0014579307008575
    • Zhou, L.; Sell, H.; Eckardt, K.; Yang, Z.; Eckel, J. Conditioned medium obtained from in. vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. FEBS Lett., 2007, 581(22), 4303-4308. (Pubitemid 47301863)
    • (2007) FEBS Letters , vol.581 , Issue.22 , pp. 4303-4308
    • Zhou, L.1    Sell, H.2    Eckardt, K.3    Yang, Z.4    Eckel, J.5
  • 58
    • 33746312598 scopus 로고    scopus 로고
    • Fatty acids bound to human serum albumin and its structural variants modulate apolipoprotein B secretion in HepG2 cells
    • DOI 10.1016/j.bbalip.2006.05.016, PII S1388198106001636
    • Ha, J.S.; Theriault, A.; Bhagavan, N.V.; Ha, C.E. Fatty acids bound to human serum albumin and its structural variants modulate apolipoprotein B secretion in HepG2 cells. Biochim. Biophys. Acta, 2006, 1761(7), 717-724. (Pubitemid 44108752)
    • (2006) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1761 , Issue.7 , pp. 717-724
    • Ha, J.-S.1    Theriault, A.2    Bhagavan, N.V.3    Ha, C.-E.4
  • 60
    • 0016724114 scopus 로고
    • Fragments of bovine serum albumin produced by limited proteolysis. Conformation and ligand binding
    • Reed, R.G.; Feldhoff, R.C.; Clute, O.L.; Peters, T., Jr. Fragments of bovine serum albumin produced by limited proteolysis. Conformation and ligand binding. Biochemistry, 1975, 14(21), 4578-4583.
    • (1975) Biochemistry , vol.14 , Issue.21 , pp. 4578-4583
    • Reed, R.G.1    Feldhoff, R.C.2    Clute, O.L.3    Peters, Jr.T.4
  • 61
    • 33745828301 scopus 로고    scopus 로고
    • Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
    • DOI 10.1152/ajpendo.00644.2005
    • Wei, Y.; Wang, D.; Topczewski, F.; Pagliassotti, M.J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am. J. Physiol. Endocrinol. Metab., 2006, 291(2), E275- 281. (Pubitemid 44035286)
    • (2006) American Journal of Physiology - Endocrinology and Metabolism , vol.291 , Issue.2
    • Wei, Y.1    Wang, D.2    Topczewski, F.3    Pagliassotti, M.J.4
  • 64
    • 34250315771 scopus 로고    scopus 로고
    • Ethanol and fish oil induce NFκB transactivation of the collagen α2(I) promoter through lipid peroxidation-driven activation of the PKC-PI3K-akt pathway
    • DOI 10.1002/hep.21659
    • Nieto, N. Ethanol and fish oil induce NFkappaB transactivation of the collagen alpha2(I) promoter through lipid peroxidation-driven activation of the PKC-PI3K-Akt pathway. Hepatology, 2007, 45(6), 1433-1445. (Pubitemid 46918327)
    • (2007) Hepatology , vol.45 , Issue.6 , pp. 1433-1445
    • Nieto, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.