Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu

Toxicological Sciences

Volumn 85, Issue 1, 2005, Pages 632-638

  van de Bovenkamp, Marja ^a,b   Groothuis, Geny M M ^b   Draaisma, Annelies L ^b   Merema, Marjolijn T ^b   Bezuijen, Judith I ^b   van Gils, Marit J ^b   Meijer, Dirk K F ^b   Friedman, Scott L ^c   Olinga, Peter ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon tetrachloride; Hepatic stellate cells; Precision cut liver slices

Indexed keywords

ALPHA CRYSTALLIN; BIOLOGICAL MARKER; CARBON TETRACHLORIDE; DESMIN; ERYTHROID KRUPPEL LIKE FACTOR; HEAT SHOCK PROTEIN 47; MESSENGER RNA;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL FUNCTION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; FIBROGENESIS; GENE OVEREXPRESSION; IN VITRO STUDY; INCUBATION TIME; LIVER FIBROSIS; LIVER SLICE; NONHUMAN; PHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; WOUND HEALING;

ANIMALS; BIOLOGICAL MARKERS; CARBON TETRACHLORIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; L-LACTATE DEHYDROGENASE; LIVER; LIVER CIRRHOSIS; MALE; MODELS, BIOLOGICAL; ORGAN CULTURE TECHNIQUES; RATS;

ANIMALIA;

EID: 18144395823     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi127     Document Type: Article

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