-
1
-
-
52949108830
-
Anticancer alkylphospholipids: Mechanisms of action, cellular sensitivity and resistance, and clinical prospects
-
van Blitterswijk, W. J., and M. Verheij. 2008. Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects. Curr. Pharm. Des. 14: 2061-2074.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2061-2074
-
-
Van Blitterswijk, W.J.1
Verheij, M.2
-
2
-
-
0034038174
-
3-induced apoptosis of human leukemic cells
-
DOI 10.1002/(SICI)1097-0215(20000415)86:2<208::AID-IJC10>3.0.CO;2-E
-
Gajate, C., A. M. Santos-Beneit, A. Macho, M. Lazaro, A. Hernandez-De Rojas, M. Modolell, E. Muñoz, and F. Mollinedo. 2000. Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells. Int. J. Cancer 86: 208-218. (Pubitemid 30180816)
-
(2000)
International Journal of Cancer
, vol.86
, Issue.2
, pp. 208-218
-
-
Gajate, C.1
Santos-Beneit, A.M.2
Macho, A.3
Lazaro, M.D.C.4
Hernandez-De, R.A.5
Modolell, M.6
Munoz, E.7
Mollinedo, F.8
-
3
-
-
0033570960
-
3 induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling
-
Cuvillier, O., E. Mayhew, A. S. Janoff, and S. Spiegel. 1999. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling. Blood 94: 3583-3592. (Pubitemid 29536155)
-
(1999)
Blood
, vol.94
, Issue.10
, pp. 3583-3592
-
-
Cuvillier, O.1
Mayhew, E.2
Janoff, A.S.3
Spiegel, S.4
-
4
-
-
1842290345
-
3 (edelfosine): Molecular structure requirements, cellular uptake, and protection by bcl-2 and bcl-x(L)
-
Mollinedo, F., J. L. Fernández-Luna, C. Gajate, B. Mart?́n-Mart?́n, A. Benito, R. Mart?́nez-Dalmau, and M. Modolell. 1997. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-XL. Cancer Res. 57: 1320-1328. (Pubitemid 27152558)
-
(1997)
Cancer Research
, vol.57
, Issue.7
, pp. 1320-1328
-
-
Mollinedo, F.1
Fernandez-Luna, J.L.2
Gajate, C.3
Martin-Martin, B.4
Benito, A.5
Martinez-Dalmau, R.6
Modolell, M.7
-
5
-
-
0034903053
-
Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac- glycero-3-phosphocholine in p53-defective hepatocytes
-
Vrablic, A. S., C. D. Albright, C. N. Craciunescu, R. I. Salganik, and S. H. Zeisel. 2001. Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac- glycero-3-phosphocholine in p53-defective hepatocytes. FASEB J. 15: 1739-1744.
-
(2001)
FASEB J.
, vol.15
, pp. 1739-1744
-
-
Vrablic, A.S.1
Albright, C.D.2
Craciunescu, C.N.3
Salganik, R.I.4
Zeisel, S.H.5
-
6
-
-
0028987154
-
Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step
-
Boggs, K. P., C. O. Rock, and S. Jackowski. 1995. Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step. J. Biol. Chem. 270: 7757-7764.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7757-7764
-
-
Boggs, K.P.1
Rock, C.O.2
Jackowski, S.3
-
7
-
-
27844522310
-
Cytotoxicity of an anti-cancer lysophospholipid through selective modification of lipid raft composition
-
Zaremberg, V., C. Gajate, L. M. Cacharro, F. Mollinedo, and C. R. McMaster. 2005. Cytotoxicity of an anti-cancer lysophospholipid through selective modification of lipid raft composition. J. Biol. Chem. 280: 38047-38058.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38047-38058
-
-
Zaremberg, V.1
Gajate, C.2
Cacharro, L.M.3
Mollinedo, F.4
McMaster, C.R.5
-
8
-
-
0037131168
-
Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis
-
van der Luit, A. H., M. Budde, P. Ruurs, M. Verheij, and W. J. van Blitterswijk. 2002. Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis. J. Biol. Chem. 277: 39541-39547.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39541-39547
-
-
Van Der Luit, A.H.1
Budde, M.2
Ruurs, P.3
Verheij, M.4
Van Blitterswijk, W.J.5
-
9
-
-
3543078747
-
Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fasen-riched rafts in selective tumor cell apoptosis
-
Gajate, C., E. Del Canto-Jañez, A. U. Acuña, F. Amat-Guerri, E. Geijo, A. M. Santos-Beneit, R. J. Veldman, and F. Mollinedo. 2004. Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fasen-riched rafts in selective tumor cell apoptosis. J. Exp. Med. 200: 353-365.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 353-365
-
-
Gajate, C.1
Del Canto-Jañez, E.2
Acuña, A.U.3
Amat-Guerri, F.4
Geijo, E.5
Santos-Beneit, A.M.6
Veldman, R.J.7
Mollinedo, F.8
-
10
-
-
64549139703
-
Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells
-
Gajate, C., F. Gonzalez-Camacho, and F. Mollinedo. 2009. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells. PLoS One 4: e5044.
-
(2009)
PLoS One
, vol.4
-
-
Gajate, C.1
Gonzalez-Camacho, F.2
Mollinedo, F.3
-
11
-
-
1642378564
-
Tracking down lipid flippases and their biological functions
-
DOI 10.1242/jcs.01055
-
Pomorski, T., J. C. Holthuis, A. Herrmann, and G. van Meer. 2004. Tracking down lipid flippases and their biological functions. J. Cell Sci. 117: 805-813. (Pubitemid 38386939)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.6
, pp. 805-813
-
-
Pomorski, T.1
Holthuis, J.C.M.2
Hermann, A.3
Van Meer, G.4
-
12
-
-
14644393694
-
Lipid traffic: Floppy drives and a super-highway
-
Holthuis, J. C., and T. P. Levine. 2005. Lipid traffic: floppy drives and a super-highway. Nat. Rev. Mol. Cell Biol. 6: 209-220.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 209-220
-
-
Holthuis, J.C.1
Levine, T.P.2
-
13
-
-
33646576217
-
Proteins involved in lipid translocation in eukaryotic cells
-
Devaux, P. F., I. López-Montero, and S. Bryde. 2006. Proteins involved in lipid translocation in eukaryotic cells. Chem. Phys. Lipids 141: 119-132.
-
(2006)
Chem. Phys. Lipids
, vol.141
, pp. 119-132
-
-
Devaux, P.F.1
López-Montero, I.2
Bryde, S.3
-
14
-
-
33847628162
-
Phospholipid flippases
-
Daleke, D. L. 2007. Phospholipid flippases. J. Biol. Chem. 282: 821-825.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 821-825
-
-
Daleke, D.L.1
-
15
-
-
77952718617
-
A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells
-
Verhulst, P. M., L. M. van der Velden, V. Oorschot, E. E. van Faassen, J. Klumperman, R. H. Houwen, T. G. Pomorski, J. C. Holthuis, and L. W. Klomp. 2010. A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. Hepatology 51: 2049-2060.
-
(2010)
Hepatology
, vol.51
, pp. 2049-2060
-
-
Verhulst, P.M.1
Van Der Velden, L.M.2
Oorschot, V.3
Van Faassen, E.E.4
Klumperman, J.5
Houwen, R.H.6
Pomorski, T.G.7
Holthuis, J.C.8
Klomp, L.W.9
-
16
-
-
0141704333
-
Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine
-
Hanson, P. K., L. Malone, J. L. Birchmore, and J. W. Nichols. 2003. Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine. J. Biol. Chem. 278: 36041-36050.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36041-36050
-
-
Hanson, P.K.1
Malone, L.2
Birchmore, J.L.3
Nichols, J.W.4
-
17
-
-
0037020182
-
A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae
-
Kato, U., K. Emoto, C. Fredriksson, H. Nakamura, A. Ohta, T. Kobayashi, K. Murakami-Murofushi, T. Kobayashi, and M. Umeda. 2002. A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae. J. Biol. Chem. 277: 37855-37862.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37855-37862
-
-
Kato, U.1
Emoto, K.2
Fredriksson, C.3
Nakamura, H.4
Ohta, A.5
Kobayashi, T.6
Murakami-Murofushi, K.7
Kobayashi, T.8
Umeda, M.9
-
18
-
-
33845987531
-
Uptake and utilization of lysophosphatidylethanolamine by Saccharomyces cerevisiae
-
Riekhof, W. R., and D. R. Voelker. 2006. Uptake and utilization of lysophosphatidylethanolamine by Saccharomyces cerevisiae. J. Biol. Chem. 281: 36588-36596.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36588-36596
-
-
Riekhof, W.R.1
Voelker, D.R.2
-
19
-
-
28844471880
-
Fluorescent, acyl chain-labeled phosphatidylcholine analogs reveal novel transport pathways across the plasma membrane of yeast
-
Elvington, S. M., F. Bu, and J. W. Nichols. 2005. Fluorescent, acyl chain-labeled phosphatidylcholine analogs reveal novel transport pathways across the plasma membrane of yeast. J. Biol. Chem. 280: 40957-40964.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40957-40964
-
-
Elvington, S.M.1
Bu, F.2
Nichols, J.W.3
-
20
-
-
16644393623
-
Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico
-
Katoh, Y., and M. Katoh. 2004. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. Oncol. Rep. 12: 939-943.
-
(2004)
Oncol. Rep.
, vol.12
, pp. 939-943
-
-
Katoh, Y.1
Katoh, M.2
-
21
-
-
0023181459
-
Perspectives in platelet-activating factor research
-
Braquet, P., L. Touqui, T. Y. Shen, and B. B. Vargaftig. 1987. Perspectives in platelet-activating factor research. Pharmacol. Rev. 39: 97-145.
-
(1987)
Pharmacol. Rev.
, vol.39
, pp. 97-145
-
-
Braquet, P.1
Touqui, L.2
Shen, T.Y.3
Vargaftig, B.B.4
-
22
-
-
0036669418
-
Platelet-activating factor receptor
-
DOI 10.1016/S0090-6980(02)00058-8, PII S0090698002000588
-
Ishii, S., T. Nagase, and T. Shimizu. 2002. Platelet-activating factor receptor. Prostaglandins Other Lipid Mediat. 68-69: 599-609. (Pubitemid 35247423)
-
(2002)
Prostaglandins and Other Lipid Mediators
, vol.68-69
, pp. 599-609
-
-
Ishii, S.1
Nagase, T.2
Shimizu, T.3
-
23
-
-
0033783028
-
Platelet-activating factor and related lipid mediators
-
Prescott, S. M., G. A. Zimmerman, D. M. Stafforini, and T. M. McIntyre. 2000. Platelet-activating factor and related lipid mediators. Annu. Rev. Biochem. 69: 419-445.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 419-445
-
-
Prescott, S.M.1
Zimmerman, G.A.2
Stafforini, D.M.3
McIntyre, T.M.4
-
24
-
-
0033061891
-
Platelet activating factor receptor (PAF-R) is found in a large endosomal compartment in human umbilical vein endothelial cells
-
Ihida, K., D. Predescu, R. P. Czekay, and G. E. Palade. 1999. Platelet activating factor receptor (PAF-R) is found in a large endosomal compartment in human umbilical vein endothelial cells. J. Cell Sci. 112: 285-295.
-
(1999)
J. Cell Sci.
, vol.112
, pp. 285-295
-
-
Ihida, K.1
Predescu, D.2
Czekay, R.P.3
Palade, G.E.4
-
25
-
-
33749080403
-
2, PAF, and LPA1 receptors
-
2, PAF, and LPA1 receptors. Can. J. Physiol. Pharmacol. 84: 377-391.
-
(2006)
Can. J. Physiol. Pharmacol.
, vol.84
, pp. 377-391
-
-
Zhu, T.1
Gobeil, F.2
Vazquez-Tello, A.3
Leduc, M.4
Rihakova, L.5
Bossolasco, M.6
Bkaily, G.7
Peri, K.8
Varma, D.R.9
Orvoine, R.10
Chemtob, S.11
-
26
-
-
0026323473
-
Platelet-activating factor and polyunsaturated fatty acids in cerebral ischemia or convulsions: Intracellular PAF-binding sites and activation of a fos/jun/AP-1 transcriptional signaling system
-
Bazan, N. G., S. P. Squinto, P. Braquet, T. Panetta, and V. L. Marcheselli. 1991. Platelet-activating factor and polyunsaturated fatty acids in cerebral ischemia or convulsions: intracellular PAF-binding sites and activation of a fos/jun/AP-1 transcriptional signaling system. Lipids 26: 1236-1242.
-
(1991)
Lipids
, vol.26
, pp. 1236-1242
-
-
Bazan, N.G.1
Squinto, S.P.2
Braquet, P.3
Panetta, T.4
Marcheselli, V.L.5
-
27
-
-
0036884098
-
Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor
-
Marrache, A. M., F. Gobeil, Jr., S. G. Bernier, J. Stankova, M. Rola-Pleszczynski, S. Choufani, G. Bkaily, A. Bourdeau, M. G. Sirois, A. Vazquez-Tello, et al. 2002. Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor. J. Immunol. 169: 6474-6481. (Pubitemid 36903498)
-
(2002)
Journal of Immunology
, vol.169
, Issue.11
, pp. 6474-6481
-
-
Marrache, A.M.1
Gobeil Jr., F.2
Bernier, S.G.3
Stankova, J.4
Rola-Pleszczynski, M.5
Choufani, S.6
Bkaily, G.7
Bourdeau, A.8
Sirois, M.G.9
Vazquez-Tello, A.10
Fan, L.11
Joyal, J.-S.12
Filep, J.G.13
Varma, D.R.14
Ribeiro-da-Silva, A.15
Chemtob, S.16
-
28
-
-
70350398248
-
Cross-talk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis
-
Melnikova, V. O., K. Balasubramanian, G. J. Villares, A. S. Dobroff, M. Zigler, H. Wang, F. Petersson, J. E. Price, A. Schroit, V. G. Prieto, et al. 2009. Cross-talk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis. J. Biol. Chem. 284: 28845-28855.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28845-28855
-
-
Melnikova, V.O.1
Balasubramanian, K.2
Villares, G.J.3
Dobroff, A.S.4
Zigler, M.5
Wang, H.6
Petersson, F.7
Price, J.E.8
Schroit, A.9
Prieto, V.G.10
-
29
-
-
0025968877
-
A model for the extracellular release of PAF: The influence of plasma membrane phospholipid asymmetry
-
Bratton, D. L., J. M. Kailey, K. L. Clay, and P. M. Henson. 1991. A model for the extracellular release of PAF: the influence of plasma membrane phospholipid asymmetry. Biochim. Biophys. Acta 1062: 24-34.
-
(1991)
Biochim. Biophys. Acta
, vol.1062
, pp. 24-34
-
-
Bratton, D.L.1
Kailey, J.M.2
Clay, K.L.3
Henson, P.M.4
-
30
-
-
46649119687
-
A yeast PAF acetylhydrolase ortholog suppresses oxidative death
-
Foulks, J. M., A. S. Weyrich, G. A. Zimmerman, and T. M. McIntyre. 2008. A yeast PAF acetylhydrolase ortholog suppresses oxidative death. Free Radic. Biol. Med. 45: 434-442.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 434-442
-
-
Foulks, J.M.1
Weyrich, A.S.2
Zimmerman, G.A.3
McIntyre, T.M.4
-
31
-
-
70350374353
-
Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XL
-
Chen, R., A. E. Feldstein, and T. M. McIntyre. 2009. Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XL. J. Biol. Chem. 284: 26297-26308.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26297-26308
-
-
Chen, R.1
Feldstein, A.E.2
McIntyre, T.M.3
-
32
-
-
34548312473
-
Cytotoxic phospholipid oxidation products. Cell death from mitochondrial damage and the intrinsic caspase cascade
-
Chen, R., L. Yang, and T. M. McIntyre. 2007. Cytotoxic phospholipid oxidation products. Cell death from mitochondrial damage and the intrinsic caspase cascade. J. Biol. Chem. 282: 24842-24850.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24842-24850
-
-
Chen, R.1
Yang, L.2
McIntyre, T.M.3
-
33
-
-
79952763477
-
Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis, by lipoprotein-associated phospholipase A2/PAF acetylhydrolase
-
In press
-
Liu, J., R. Chen, G. K. Marathe, M. Febbraio, W. Zou, and T. M McIntyre. 2010. Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis, by lipoprotein-associated phospholipase A2/PAF acetylhydrolase. Circ. Res. In press.
-
(2010)
Circ. Res.
-
-
Liu, J.1
Chen, R.2
Marathe, G.K.3
Febbraio, M.4
Zou, W.5
McIntyre, T.M.6
-
35
-
-
0037064036
-
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions
-
Podrez, E. A., E. Poliakov, Z. Shen, R. Zhang, Y. Deng, M. Sun, P. J. Finton, L. Shan, M. Febbraio, D. P. Hajjar, et al. 2002. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J. Biol. Chem. 277: 38517-38523.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38517-38523
-
-
Podrez, E.A.1
Poliakov, E.2
Shen, Z.3
Zhang, R.4
Deng, Y.5
Sun, M.6
Finton, P.J.7
Shan, L.8
Febbraio, M.9
Hajjar, D.P.10
-
36
-
-
77954566401
-
Chronic alcohol exposure increases circulating bioactive oxidized phospholipids
-
Yang, L., C. Latchoumycandane, M. R. McMullen, B. T. Pratt, R. Zhang, B. G. Papouchado, L. E. Nagy, A. E. Feldstein, and T. M. McIntyre. 2010. Chronic alcohol exposure increases circulating bioactive oxidized phospholipids. J. Biol. Chem. 285: 22211-22220.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22211-22220
-
-
Yang, L.1
Latchoumycandane, C.2
McMullen, M.R.3
Pratt, B.T.4
Zhang, R.5
Papouchado, B.G.6
Nagy, L.E.7
Feldstein, A.E.8
McIntyre, T.M.9
-
37
-
-
27444446947
-
Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage
-
Marathe, G. K., C. Johnson, S. D. Billings, M. D. Southall, Y. Pei, D. Spandau, R. C. Murphy, G. A. Zimmerman, T. M. McIntyre, and J. B. Travers. 2005. Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage. J. Biol. Chem. 280: 35448-35457.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35448-35457
-
-
Marathe, G.K.1
Johnson, C.2
Billings, S.D.3
Southall, M.D.4
Pei, Y.5
Spandau, D.6
Murphy, R.C.7
Zimmerman, G.A.8
McIntyre, T.M.9
Travers, J.B.10
-
38
-
-
0030926826
-
Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking
-
Lehr, H. A., A. S. Weyrich, R. K. Saetzler, A. Jurek, K. E. Arfors, G. A. Zimmerman, S. M. Prescott, and T. M. McIntyre. 1997. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J. Clin. Invest. 99: 2358-2364.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2358-2364
-
-
Lehr, H.A.1
Weyrich, A.S.2
Saetzler, R.K.3
Jurek, A.4
Arfors, K.E.5
Zimmerman, G.A.6
Prescott, S.M.7
McIntyre, T.M.8
-
39
-
-
38649113883
-
ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity
-
Paulusma, C. C., D. E. Folmer, K. S. Ho-Mok, D. R. de Waart, P. M. Hilarius, A. J. Verhoeven, and R. P. Oude Elferink. 2008. ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity. Hepatology 47: 268-278.
-
(2008)
Hepatology
, vol.47
, pp. 268-278
-
-
Paulusma, C.C.1
Folmer, D.E.2
Ho-Mok, K.S.3
De Waart, D.R.4
Hilarius, P.M.5
Verhoeven, A.J.6
Oude Elferink, R.P.7
-
40
-
-
6044275973
-
Fluorescent phenylpolyene analogues of the ether phospholipid edelfosine for the selective labeling of cancer cells
-
Quesada, E., J. Delgado, C. Gajate, F. Mollinedo, A. U. Acuña, and F. Amat-Guerri. 2004. Fluorescent phenylpolyene analogues of the ether phospholipid edelfosine for the selective labeling of cancer cells. J. Med. Chem. 47: 5333-5335.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 5333-5335
-
-
Quesada, E.1
Delgado, J.2
Gajate, C.3
Mollinedo, F.4
Acuña, A.U.5
Amat-Guerri, F.6
-
41
-
-
0032981815
-
Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: Involvement of the Fas receptor/ligand system
-
Cabaner, C., C. Gajate, A. Macho, E. Muñoz, M. Modolell, and F. Mollinedo. 1999. Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system. Br. J. Pharmacol. 127: 813-825.
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 813-825
-
-
Cabaner, C.1
Gajate, C.2
Macho, A.3
Muñoz, E.4
Modolell, M.5
Mollinedo, F.6
-
42
-
-
0033974266
-
Intracellular triggering of FAS, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis
-
DOI 10.1002/(SICI)1097-0215(20000301)85:5<674::AID-IJC13>3.0.CO;2-Z
-
Gajate, C., R. I. Fonteriz, C. Cabaner, G. Alvarez-Noves, Y. Alvarez-Rodriguez, M. Modolell, and F. Mollinedo. 2000. Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis. Int. J. Cancer 85: 674-682. (Pubitemid 30080481)
-
(2000)
International Journal of Cancer
, vol.85
, Issue.5
, pp. 674-682
-
-
Gajate, C.1
Fonteriz, R.I.2
Cabaner, C.3
Alvarez-Noves, G.4
Alvarez-Rodriguez, Y.5
Modolell, M.6
Mollinedo, F.7
-
43
-
-
78650051607
-
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4 ATPases
-
van der Velden, L. M., C. G. Wichers, A. E. van Breevoort, J. A. Coleman, R. S. Molday, R. Berger, L. W. Klomp, and S. F. van de Graaf. 2010. Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4 ATPases. J. Biol. Chem. 285: 40088-40096.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40088-40096
-
-
Van Der Velden, L.M.1
Wichers, C.G.2
Van Breevoort, A.E.3
Coleman, J.A.4
Molday, R.S.5
Berger, R.6
Klomp, L.W.7
Van De Graaf, S.F.8
-
44
-
-
3042728119
-
Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae
-
Saito, K., K. Fujimura-Kamada, N. Furuta, U. Kato, M. Umeda, and K. Tanaka. 2004. Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol. Biol. Cell 15: 3418-3432.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3418-3432
-
-
Saito, K.1
Fujimura-Kamada, K.2
Furuta, N.3
Kato, U.4
Umeda, M.5
Tanaka, K.6
-
45
-
-
5644241027
-
Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity
-
DOI 10.1111/j.1365-2443.2004.00782.x
-
Iwamoto, K., S. Kobayashi, R. Fukuda, M. Umeda, T. Kobayashi, and A. Ohta. 2004. Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity. Genes Cells 9: 891-903. (Pubitemid 39369022)
-
(2004)
Genes to Cells
, vol.9
, Issue.10
, pp. 891-903
-
-
Iwamoto, K.1
Kobayashi, S.2
Fukuda, R.3
Umeda, M.4
Kobayashi, T.5
Ohta, A.6
-
46
-
-
33846177595
-
Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway
-
Furuta, N., K. Fujimura-Kamada, K. Saito, T. Yamamoto, and K. Tanaka. 2007. Endocytic recycling in yeast is regulated by putative phospholipid translocases and the Ypt31p/32p-Rcy1p pathway. Mol. Biol. Cell 18: 295-312.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 295-312
-
-
Furuta, N.1
Fujimura-Kamada, K.2
Saito, K.3
Yamamoto, T.4
Tanaka, K.5
-
47
-
-
35548947966
-
Transbilayer Phospholipid Flipping Regulates Cdc42p Signaling during Polarized Cell Growth via Rga GTPase-Activating Proteins
-
DOI 10.1016/j.devcel.2007.09.014, PII S1534580707003553
-
Saito, K., K. Fujimura-Kamada, H. Hanamatsu, U. Kato, M. Umeda, K. G. Kozminski, and K. Tanaka. 2007. Transbilayer phospholipid flipping regulates Cdc42p signaling during polarized cell growth via Rga GTPase-activating proteins. Dev. Cell 13: 743-751. (Pubitemid 350011986)
-
(2007)
Developmental Cell
, vol.13
, Issue.5
, pp. 743-751
-
-
Saito, K.1
Fujimura-Kamada, K.2
Hanamatsu, H.3
Kato, U.4
Umeda, M.5
Kozminski, K.G.6
Tanaka, K.7
-
48
-
-
36549038241
-
Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: Antiangiogenic properties of a new class of antitumor agents
-
DOI 10.1097/CAD.0b013e3282f16d36, PII 0000181320080100000008
-
Zerp, S. F., S. R. Vink, G. A. Ruiter, P. Koolwijk, E. Peters, A. H. van der Luit, D. de Jong, M. Budde, H. Bartelink,W. J. van Blitterswijk, and M. Verheij. 2008. Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: antiangiogenic properties of a new class of antitumor agents. Anticancer Drugs 19: 65-75. (Pubitemid 350190969)
-
(2008)
Anti-Cancer Drugs
, vol.19
, Issue.1
, pp. 65-75
-
-
Zerp, S.F.1
Vink, S.R.2
Ruiter, G.A.3
Koolwijk, P.4
Peters, E.5
Van Der, L.A.H.6
De Jong, D.7
Budde, M.8
Bartelink, H.9
Van Blitterswijk, W.J.10
Verheij, M.11
-
49
-
-
0030872157
-
Dissociation of the effects of the antitumour ether lipid ET-18-OCH3 on cytosolic calcium and on apoptosis
-
Alonso, M. T., C. Gajate, F. Mollinedo, M. Modolell, J. Alvarez, and J. García-Sancho. 1997. Dissociation of the effects of the antitumour ether lipid ET-18-OCH3 on cytosolic calcium and on apoptosis. Br. J. Pharmacol. 121: 1364-1368.
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 1364-1368
-
-
Alonso, M.T.1
Gajate, C.2
Mollinedo, F.3
Modolell, M.4
Alvarez, J.5
García-Sancho, J.6
-
50
-
-
33747639280
-
Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites
-
Pérez-Victoria, F. J., M. P. Sánchez-Cañete, S. Castanys, and F. Gamarro. 2006. Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites. J. Biol. Chem. 281: 23766-23775.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23766-23775
-
-
Pérez-Victoria, F.J.1
Sánchez-Cañete, M.P.2
Castanys, S.3
Gamarro, F.4
-
51
-
-
65649096220
-
Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug
-
Sánchez-Cañete, M. P., L. Carvalho, F. J. Pérez-Victoria, F. Gamarro, and S. Castanys. 2009. Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob. Agents Chemother. 53: 1305-1313.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 1305-1313
-
-
Sánchez-Cañete, M.P.1
Carvalho, L.2
Pérez-Victoria, F.J.3
Gamarro, F.4
Castanys, S.5
-
52
-
-
0033912094
-
Increase in fragmented phosphatidylcholine in blood plasma by oxidative stress
-
Frey, B., R. Haupt, S. Alms, G. Holzmann, T. König, H. Kern, W. Kox, B. Rüstow, and M. Schlame. 2000. Increase in fragmented phosphatidylcholine in blood plasma by oxidative stress. J. Lipid Res. 41: 1145-1153. (Pubitemid 30483020)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.7
, pp. 1145-1153
-
-
Frey, B.1
Haupt, R.2
Alms, S.3
Holzmann, G.4
Konig, T.5
Kern, H.6
Kox, W.7
Rustow, B.8
Schlame, M.9
-
53
-
-
0036634160
-
Bioactive oxidized lipids in the plasma of cardiac surgical intensive care patients
-
Frey, B., W. Johnen, R. Haupt, H. Kern, B. Rüstow, W. J. Kox, and M. Schlame. 2002. Bioactive oxidized lipids in the plasma of cardiac surgical intensive care patients. Shock 18: 14-17.
-
(2002)
Shock
, vol.18
, pp. 14-17
-
-
Frey, B.1
Johnen, W.2
Haupt, R.3
Kern, H.4
Rüstow, B.5
Kox, W.J.6
Schlame, M.7
-
54
-
-
45349107192
-
UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system
-
Zhang, Q., Y. Yao, R. L. Konger, A. L. Sinn, S. Cai, K. E. Pollok, and J. B. Travers. 2008. UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system. J. Invest. Dermatol. 128: 1780-1787.
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 1780-1787
-
-
Zhang, Q.1
Yao, Y.2
Konger, R.L.3
Sinn, A.L.4
Cai, S.5
Pollok, K.E.6
Travers, J.B.7
-
55
-
-
0025908558
-
Human plasma platelet-activating factor acetylhydrolase: Oxidatively fragmented phospholipids as substrates
-
Stremler, K. E., D. M. Stafforini, S. M. Prescott, and T. M. McIntyre. 1991. Human plasma platelet-activating factor acetylhydrolase: oxidatively fragmented phospholipids as substrates. J. Biol. Chem. 266: 11095-11103.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11095-11103
-
-
Stremler, K.E.1
Stafforini, D.M.2
Prescott, S.M.3
McIntyre, T.M.4
-
57
-
-
0036556784
-
Activation of vascular cells by PAF-like lipids in oxidized LDL
-
Marathe, G. K., G. A. Zimmerman, S. M. Prescott, and T. M. McIntyre. 2002. Activation of vascular cells by PAF-like lipids in oxidized LDL. Vascul. Pharmacol. 38: 193-200.
-
(2002)
Vascul. Pharmacol.
, vol.38
, pp. 193-200
-
-
Marathe, G.K.1
Zimmerman, G.A.2
Prescott, S.M.3
McIntyre, T.M.4
-
58
-
-
71549140677
-
2, a marker of vascular inflammation and systemic vulnerability
-
2, a marker of vascular inflammation and systemic vulnerability. Eur. Heart J. 30: 2829-2831.
-
(2009)
Eur. Heart J.
, vol.30
, pp. 2829-2831
-
-
Münzel, T.1
Gori, T.2
|