Activation of vascular cells by PAF-like lipids in oxidized LDL

Vascular Pharmacology

Volumn 38, Issue 4, 2002, Pages 193-200

  Marathe, Gopal K ^a,b   Zimmerman, Guy A ^a,b   Prescott, Stephen M ^c   McIntyre, Thomas M ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Inflammation; Monocyte; Oxidized low density lipoproteins; PAF

Indexed keywords

ACETIC ACID; CHOLINE DERIVATIVE; FATTY ACID; GINKGOLIDE B; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; THROMBOCYTE ACTIVATING FACTOR LIKE LIPID; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; CELL ACTIVATION; CELL ACTIVITY; CELL FUNCTION; CONTROLLED STUDY; FOAM CELL; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; MOLECULAR MIMICRY; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN FUNCTION; THROMBOCYTE;

BLOOD VESSELS; CALCIUM SIGNALING; CELL ADHESION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORESCENT DYES; FURA-2; HUMANS; LIPOPROTEINS, LDL; MONOCYTES; NEUTROPHILS; OXIDATION-REDUCTION; PHOSPHOLIPIDS; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; STIMULATION, CHEMICAL;

EID: 0036556784     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1537-1891(02)00169-6     Document Type: Article

References (61)

1. Berliner J.A., Heinecke J.W. The role of oxidized lipoproteins in atherogenesis. Free Radic. Biol. Med. 20:1996;707-727.
2. Cines D.B., Pollak E.S., Buck C.A.et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood. 91:1998;3527-3561.
3. Cohnheim J. Lectures on General Pathology. A Handbook for Practitioners and Students. 1889;New Sydenham Society, London.
4. Davies S.S., Pontsler A.V., Marathe G.K.et al. Oxidized phospholipids are specific, high affinity PPAR{gamma} ligands and agonists. J. Biol. Chem. 276:2001;16015-16023.
5. Diagne A., Fauvel J., Record M.et al. Studies on ether phospholipids: comparative composition of various tissues from human, rat and guinea pig. Biochim. Biophys. Acta. 793:1984;221-231.
6. Dong Z.M., Chapman S.M., Brown A.A.et al. The combined role of P- and E-selectins in atherosclerosis. J. Clin. Invest. 102:1998;145-152.
7. Elstad M.R., Prescott S.M., McIntyre T.M.et al. Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes. J. Immunol. 140:1988;1618-1624.
8. Feliste R., Perret B., Braquet P.et al. Protective effect of BN 52021, a specific antagonist of platelet-activating factor (PAF-acether) against diet-induced cholesteryl ester deposition in rabbit aorta. Atherosclerosis. 78:1989;151-158.
9. Frei B., Stocker R., Ames B.N. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc. Natl. Acad. Sci. U. S. A. 85:1988;9748-9752.
10. Frenette P.S., Moyna C., Hartwell D.W.et al. Platelet-endothelial interactions in inflamed mesenteric venules. Blood. 91:1998;1318-1324.
11. Frey B., Haupt R., Alms S.et al. Increase in fragmented phosphatidylcholine in blood plasma by oxidative stress. J. Lipid Res. 41:2000;1145-1153.
12. Guyton J.R. Phospholipid hydrolytic enzymes in a 'cesspool' of arterial intimal lipoproteins: a mechanism for atherogenic lipid accumulation. Arterioscler. Thromb. Vasc. Biol. 21:2001;884-886.
13. Heery J.M., Kozak M., Stafforini D.M.et al. Oxidatively modified LDL contains phospholipids with PAF-like activity and stimulates the growth of smooth muscle cells. J. Clin. Invest. 96:1995;2322-2330.
14. Holland M.R., Whatley R.E., Stroud E.D.et al. Activation of the acetyl-CoA: LysoPAF acetyltransferase regulates platelet activating factor synthesis in endothelial cells. Circulation. 82:1990;III-372.
15. Honda Z., Nakamura M., Miki I.et al. Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung. Nature. 349:1991;342-346.
16. Hwang S.-B. Identification of a second putative receptor of platelet-activating factor from human polymorphonuclear leukocytes. J. Biol. Chem. 263:1988;3225-3233.
17. Recombinant platelet activating factor acetylhydrolase (PAFASE) decreases the incidence of acute respiratory distress syndrome (ARDS) and 28 day all cause mortality. Intensive Care Med. 26:2000;S321.
18. Imaizumi T., Satoh K., Yoshida H.et al. Effect of cigarette smoking on the levels of platelet-activating factor-like lipid(s) in plasma lipoproteins. Atherosclerosis. 87:1991;47-55.
19. Lawson J.A., Rokach J., FitzGerald G.A. Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo. J. Biol. Chem. 274:1999;24441-24444.
20. Lee H., Shi W., Tontonoz P.et al. Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circ. Res. 87:2000;516-521.
21. Lehr H.A., Kress E., Menger M.D.et al. Cigarette smoke elicits leukocyte adhesion to endothelium in hamsters: inhibition by CuZn-SOD. Free Radic. Biol. Med. 14:1993;573-581.
22. Lehr H.A., Seemuller J., Hubner C.et al. Oxidized LDL-induced leukocyte/endothelium interaction in vivo involves the receptor for platelet-activating factor. Arterioscler. Thromb. 13:1993;1013-1018.
23. Lehr H.A., Frei B., Arfors K.E. Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc. Natl. Acad. Sci. U. S. A. 91:1994;7688-7692.
24. Lehr H.A., Weyrich A.S., Saetzler R.K.et al. Vitamin C blocks inflammatory PAF mimetics created by cigarette smoking. J. Clin. Invest. 99:1997;2358-2364.
25. Marathe G.K., Davies S.S., Harrison K.A.et al. Inflammatory PAF-like lipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. J. Biol. Chem. 274:1999;28395-28405.
26. Marathe G.K., Harrison K.A., Murphy R.C.et al. Bioactive phospholipid oxidation products. Free Radic. Biol. Med. 28:2000;1762-1770.
27. Marathe G.K., Harrison K.A., Roberts L.J. IIet al. Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. J. Lipid Res. 42:2001;587-596.
28. Marathe G.K., Silva A.R., de Castro Faria Neto H.C.et al. Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids. J. Lipid Res. 42:2001;1430-1437.
29. McIntyre T.M., Zimmerman G.A., Satoh K.et al. Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. J. Clin. Invest. 76:1985;271-280.
30. 4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc. Natl. Acad. Sci. U. S. A. 83:1986;2204-2208.
31. McIntyre T.M., Zimmerman G.A., Prescott S.M. Biologically active oxidized phospholipids. J. Biol. Chem. 274:1999;25189-25192.
32. O'Flaherty J.T., Salzer W.L., Cousart S.et al. Platelet-activating factor and analogues: comparative studies with human neutrophils and rabbit platelets. Res. Commun. Chem. Pathol. Pharmacol. 39:1983;291-309.
33. Prescott S.M., Zimmerman G.A., Stafforini D.M.et al. Platelet-activating factor and related lipid mediators. Annu. Rev. Biochem. 69:2000;419-445.
34. Pryor W.A., Stone K. Oxidants in cigarette smoke. Ann. N.Y. Acad. Sci. 686:1993;12-28.
35. Quarck R., De Geest B., Stengel D.et al. Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice. Circulation. 103:2001;2495-2500.
36. Roberts L.J. II, Morrow J.D. The generation and actions of isoprostanes. Biochim. Biophys. Acta. 1345:1997;121-135.
37. Ross R. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340:1999;115-126.
38. Shimizu T., Honda Z., Nakamura M.et al. Platelet-activating factor receptor and signal transduction. Biochem. Pharmacol. 44:1992;1001-1008.
39. Siess W., Zangl K.J., Essler M.et al. Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc. Natl. Acad. Sci. U. S. A. 96:1999;6931-6936.
40. Smiley P.L., Stremler K.E., Prescott S.M.et al. Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. J. Biol. Chem. 266:1991;11104-11110.
41. Stafforini D.M., Prescott S.M., McIntyre T.M. Human plasma platelet-activating factor acetylhydrolase: purification and properties. J. Biol. Chem. 262:1987;4223-4230.
42. Stafforini D.M., Prescott S.M., McIntyre T.M. Platelet-activating factor acetylhydrolase in human erythrocytes. FASEB J. 2:1988;A1375.
43. Stafforini D.M., Carter M.E., Zimmerman G.A.et al. Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma. Proc. Natl. Acad. Sci. U. S. A. 86:1989;2393-2397.
44. Stafforini D.M., McIntyre T.M., Zimmerman G.A.et al. Platelet-activating factor acetylhydrolases. J. Biol. Chem. 272:1997;17895-17898.
45. Steinberg D. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272:1997;20963-20966.
46. Stenberg P.E., McEver R.P., Shuman M.A.et al. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J. Cell. Biol. 101:1985;880-886.
47. Stremler K.E., Stafforini D.M., Prescott S.M.et al. An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma. J. Biol. Chem. 264:1989;5331-5334.
48. Stremler K.E., Stafforini D.M., Prescott S.M.et al. Human plasma platelet-activating factor acetylhydrolase: oxidatively-fragmented phospholipids as substrates. J. Biol. Chem. 266:1991;11095-11103.
49. Subbanagounder G., Leitinger N., Shih P.T.et al. Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis: in vitro and In vivo inhibition by WEB 2086. Circ. Res. 85:1999;311-318.
50. 2+/ascorbate/EDTA-induced lipid peroxidation. Biochim. Biophys. Acta. 1166:1993;264-274.
51. Tanaka T., Iimori M., Tsukatani H.et al. Platelet-aggregating effects of platelet-activating factor-like phospholipids formed by oxidation of phosphatidylcholines containing an sn-2-polyunsaturated fatty acyl group. Biochim. Biophys. Acta. 1210:1994;202-208.
52. Tokumura A., Kamiyasu K., Takauchi K.et al. Evidence for existence of various homologues and analogues of platelet activating factor in a lipid extract of bovine brain. Biochem. Biophys. Res. Commun. 145:1987;415-425.
53. van Tits L.J., Hak-Lemmers H.L., Demacker P.N.et al. Oxidized low-density lipoprotein induces calcium influx in polymorphonuclear leukocytes. Free Radic. Biol. Med. 29:2000;747-755.
54. Watson A.D., Leitinger N., Navab M.et al. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J. Biol. Chem. 272:1997;13597-13607.
55. Weyrich A.S., McIntyre T.M., McEver R.P.et al. Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-α secretion: signal integration and NF-kB translocation. J. Clin. Invest. 95:1995;2297-2303.
56. Weyrich A.S., Elstad M.R., McEver R.P.et al. Activated platelets signal chemokine synthesis by human monocytes. J. Clin. Invest. 97:1996;1525-1534.
57. Whatley R.E., Nelson P., Zimmerman G.A.et al. The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C. J. Biol. Chem. 264:1989;6325-6333.
58. Yamada Y., Ichihara S., Fujimura T.et al. Identification of the G994→T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men. Metabolism. 47:1998;177-181.
59. Zimmerman G.A., McIntyre T.M. Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms. J. Clin. Invest. 81:1988;531-537.
60. Zimmerman G.A., McIntyre T.M., Prescott S.M. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J. Clin. Invest. 76:1985;2235-2246.
61. Zimmerman G.A., McIntyre T.M., Prescott S.M. Walz D.A., Fenton J.W. II, Shuman M.A. Bioregulatory Functions of Thrombin. vol. 485:1986;349-368 Annals of the New York Academy of Sciences, New York.