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Volumn 53, Issue 4, 2009, Pages 1305-1313

Low plasma membrane expression of the miltefosine transport complex renders leishmania braziliensis refractory to the drug

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; LDMT PROTEIN; LDROS3 PROTEIN; MILTEFOSINE; UNCLASSIFIED DRUG;

EID: 65649096220     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01694-08     Document Type: Article
Times cited : (71)

References (23)
  • 3
    • 33847685204 scopus 로고    scopus 로고
    • In vitro activity of perifosine: A novel alkylphospholipid against the promastigote stage of Leishmania species
    • DOI 10.1007/s00436-006-0408-4
    • Cabrera-Serra, M. G., J. Lorenzo-Morales, M. Romero, B. Valladares, and J. E. Pinero. 2007. In vitro activity of perifosine: a novel alkylphospholipid against the promastigote stage of Leishmania species. Parasitol. Res. 100: 1155-1157. (Pubitemid 46354882)
    • (2007) Parasitology Research , vol.100 , Issue.5 , pp. 1155-1157
    • Cabrera-Serra, M.G.1    Lorenzo-Morales, J.2    Romero, M.3    Valladares, B.4    Pinero, J.E.5
  • 5
    • 0036150927 scopus 로고    scopus 로고
    • 3 (edelfosine) and amphotericin B
    • DOI 10.1016/S0001-706X(01)00197-8, PII S0001706X01001978
    • Escobar, P., S. Matu, C. Marques, and S. L. Croft. 2002. Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta Trop. 81:151-157. (Pubitemid 34093805)
    • (2002) Acta Tropica , vol.81 , Issue.2 , pp. 151-157
    • Escobar, P.1    Matu, S.2    Marques, C.3    Croft, S.L.4
  • 6
    • 0343267840 scopus 로고    scopus 로고
    • Use of the green fluorescent protein as a marker in transfected Leishmania
    • DOI 10.1016/0166-6851(96)02580-7
    • Ha, D. S., J. K. Schwarz, S. J. Turco, and S. M. Beverley. 1996. Use of the green fluorescent protein as a marker in transfected Leishmania. Mol. Biochem. Parasitol. 77:57-64. (Pubitemid 26186162)
    • (1996) Molecular and Biochemical Parasitology , vol.77 , Issue.1 , pp. 57-64
    • Sean Ha, D.1    Schwarz, J.K.2    Turco, S.J.3    Beverley, S.M.4
  • 7
    • 0031553979 scopus 로고    scopus 로고
    • Automated laser-induced fluorescence DNA sequencing: Equalizing signal-to-noise ratios significantly enhances overall performance
    • DOI 10.1006/abio.1996.9933
    • Lario, A, A. González, and G. Dorado. 1997. Automated laser-induced fluorescence DNA sequencing: equalizing signal-to-noise ratios significantly enhances overall performance. Anal. Biochem. 247:30-33. (Pubitemid 27161489)
    • (1997) Analytical Biochemistry , vol.247 , Issue.1 , pp. 30-33
    • Lario, A.1    Gonzalez, A.2    Dorado, G.3
  • 8
    • 34247178377 scopus 로고    scopus 로고
    • Cutaneous leishmaniasis treatment
    • DOI 10.1016/j.tmaid.2006.09.004, PII S1477893906001025
    • Minodier, P., and P. Parola. 2007. Cutaneous leishmaniasis treatment. Travel Med. Infect. Dis. 5:150-158. (Pubitemid 46585958)
    • (2007) Travel Medicine and Infectious Disease , vol.5 , Issue.3 , pp. 150-158
    • Minodier, P.1    Parola, P.2
  • 9
    • 1842290345 scopus 로고    scopus 로고
    • 3 (edelfosine): Molecular structure requirements, cellular uptake, and protection by bcl-2 and bcl-x(L)
    • Mollinedo, F., J. L. Fernández-Luna, C. Gajate, B. Martín-Martín, A. Benito, R. Martínez-Dalmau, and M. Modolell. 1997. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (edelfosine): mo-lecular structure requirements, cellular uptake, and protection by Bcl-2 and BCI-XL. Cancer Res. 57:1320-1328. (Pubitemid 27152558)
    • (1997) Cancer Research , vol.57 , Issue.7 , pp. 1320-1328
    • Mollinedo, F.1    Fernandez-Luna, J.L.2    Gajate, C.3    Martin-Martin, B.4    Benito, A.5    Martinez-Dalmau, R.6    Modolell, M.7
  • 10
    • 0041767590 scopus 로고    scopus 로고
    • Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug
    • DOI 10.1128/AAC.47.8.2397-2403.2003
    • Pérez-Victoria, F. J., S. Castanys, and F. Gamarro. 2003. Leishmania dono-vani resistance to miltefosine involves a defective inward translocation of the drag. Antimicrob. Agents Chemother. 47:2397-2403. (Pubitemid 36919436)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.8 , pp. 2397-2403
    • Perez-Victoria, F.J.1    Castanys, S.2    Gamarro, F.3
  • 11
    • 0346118937 scopus 로고    scopus 로고
    • Functional cloning of the miltefosine transporter: A novel p-type phospholipid translocase from leishmania involved in drug resistance
    • DOI 10.1074/jbc.M308352200
    • Pérez-Victoria, F. J., F. Gamarro, M. Ouellette, and S. Castanys. 2003. Functional cloning of the miltefosine transporter. A novel P-type phospho-lipid translocase from Leishmania involved in drug resistance. J. Biol. Chem. 278:49965-49971. (Pubitemid 37548832)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.50 , pp. 49965-49971
    • Perez-Victoria, F.J.1    Gamarro, F.2    Ouellette, M.3    Castanys, S.4
  • 12
    • 33747639280 scopus 로고    scopus 로고
    • Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites
    • DOI 10.1074/jbc.M605214200
    • Pérez-Victoria, F. J., M. P. Sánchez-Cañete, S. Castanys, and F. Gamarro. 2006. Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites. J. Biol. Chem. 281:23766-23775. (Pubitemid 44274152)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.33 , pp. 23766-23775
    • Perez-Victoria, F.J.1    Sanchez-Canete, M.P.2    Castanys, S.3    Gamarro, F.4
  • 13
    • 33745253122 scopus 로고    scopus 로고
    • Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use
    • DOI 10.1016/j.drup.2006.04.001, PII S1368764606000215
    • Pérez-Victoria, F. J., M. P. Sánchez-Cañete, K. Seifert, S. L. Croft, S. Sundar, S. Castanys, and F. Gamarro. 2006. Mechanisms of experimental resistance of Leishmania to miltefosine: implications for clinical use. Drug Resist. Updat. 9:26-39. (Pubitemid 43928805)
    • (2006) Drug Resistance Updates , vol.9 , Issue.1-2 , pp. 26-39
    • Perez-Victoria, F.J.1    Sanchez-Canete, M.P.2    Seifert, K.3    Croft, S.L.4    Sundar, S.5    Castanys, S.6    Gamarro, F.7
  • 14
    • 34547337720 scopus 로고    scopus 로고
    • Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo
    • DOI 10.1016/j.ijantimicag.2007.05.007, PII S092485790700252X
    • Seifert, K., F. J. Pérez-Victoria, M. Stettier, M. P. Sánchez-Cañete, S. Cas-tanys, F. Gamarro, and S. L. Croft. 2007. Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. Int. J. Anti-microb. Agents 30:229-235. (Pubitemid 47135625)
    • (2007) International Journal of Antimicrobial Agents , vol.30 , Issue.3 , pp. 229-235
    • Seifert, K.1    Perez-Victoria, F.J.2    Stettler, M.3    Sanchez-Canete, M.P.4    Castanys, S.5    Gamarro, F.6    Croft, S.L.7
  • 15
    • 0030816631 scopus 로고    scopus 로고
    • Characterization of an HL-60 cell variant resistant to the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
    • DOI 10.1007/s11745-997-0091-3
    • Small, G. W., J. C. Strum, and L. W. Daniel. 1997. Characterization of an HL-60 cell variant resistant to the antineoplastic ether lipid 1-O-octadecyl-2-0-methyl-rac-glycero-3-phosphocholine. Lipids 32:715-723. (Pubitemid 27328052)
    • (1997) Lipids , vol.32 , Issue.7 , pp. 715-723
    • Small, G.W.1    Strum, J.C.2    Daniel, L.W.3
  • 17
    • 33749336171 scopus 로고    scopus 로고
    • Treatment of New World cutaneous leishmaniasis with miltefosine
    • DOI 10.1016/j.trstmh.2006.02.022, PII S0035920306002112
    • Soto, J., and J. Berman. 2006. Treatment of New World cutaneous leish-maniasis with miltefosine. Trans. R. Soc. Trop. Med. Hyg. 100(Suppl. 1): S34-S40. (Pubitemid 44490170)
    • (2006) Transactions of the Royal Society of Tropical Medicine and Hygiene , vol.100 , Issue.SUPPL. 1
    • Soto, J.1    Berman, J.2
  • 23
    • 0029147362 scopus 로고
    • Animal cell mutants unable to take up biologically active glycerophospholipids
    • Zoeller, R. A., M. D. Layne, and E. J. Modest. 1995. Animal cell mutants unable to take up biologically active glycerophospholipids. J. Lipid Res. 36:1866-1875.
    • (1995) J. Lipid Res. , vol.36 , pp. 1866-1875
    • Zoeller, R.A.1    Layne, M.D.2    Modest, E.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.