Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1A mutations

Journal of Neuroscience

Volumn 31, Issue 11, 2011, Pages 4311-4326

  Mark, Melanie D ^a   Maejima, Takashi ^a   Kuckelsberg, Denise ^a   Yoo, Jong W ^c   Hyde, Robert A ^b   Shah, Viral ^b   Gutierrez, Davina ^b   Moreno, Rosa L ^d   Kruse, Wolfgang ^a   Noebels, Jeffrey L ^c   Herlitze, Stefan ^a,b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATAXIA; CACNA1A GENE; CEREBELLUM; CONTROLLED STUDY; DYSKINESIA; FOREBRAIN; GENE; GENE DELETION; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PURKINJE CELL;

ANALYSIS OF VARIANCE; ANIMALS; ATAXIA; CALCIUM CHANNELS, P-TYPE; CALCIUM CHANNELS, Q-TYPE; CEREBELLUM; DYSKINESIAS; ELECTROENCEPHALOGRAPHY; ELECTROPHYSIOLOGY; EPILEPSY, ABSENCE; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE; MICE, TRANSGENIC; MUTATION; PHENOTYPE; PURKINJE CELLS;

EID: 79952755742     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5342-10.2011     Document Type: Article

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