Presynaptic Ca2+ influx at a mouse central synapse with Ca2+ channel subunit mutations

Journal of Neuroscience

Volumn 20, Issue 1, 2000, Pages 163-170

  Qian, Jing ^a   Noebels, Jeffrey L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cooperativity; Hippocampus; Magnesium green; Power function; PPF; Presynaptic terminal; Transmitter release

Indexed keywords

CALCIUM CHANNEL; GUANINE NUCLEOTIDE BINDING PROTEIN; OMEGA CONOTOXIN GVIA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; HIPPOCAMPUS; MOUSE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN INTERACTION; SYNAPSE; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP;

EID: 0033994299     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-01-00163.2000     Document Type: Article

References (37)

1. Borst JGG, Sakmann B (1996) Calcium influx and transmitter release in a fast CNS synapse. Nature 383:431-434.
2. Burgess DL, Noebels JL (1999) Voltage-dependent calcium channel mutations in neurological disease. Ann NY Acad Sci 868:199-212.
3. 2+ channel β subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell 88:385-392.
4. 2+ channel subunit compositions in lethargic mouse brain. Mol Cell Neurosci 13:293-311.
5. tg) mouse thalami. J Neurophysiol 81:2066-2074.
6. Campbell V, Borrow NS, Fitzgerald EM, Brickley K, Dolphin AC (1995) Inhibition of the interaction of G protein G(o) with calcium channels by the calcium channel beta-subunit in rat neurones. J Physiol (Lond) 485:365-372.
7. De Waard M, Liu H, Walker D, Scott VE, Gurnett CA, Campbell KP (1997) Direct binding of G-protein beta gamma complex to voltage-dependent calcium channels. Nature 385:446-650.
8. Dodge Jr FA, Rahamimoff R (1967) Co-operative action of calcium ions in transmitter release at the neuromuscular junction. J Physiol (Lond) 193:419-432.
9. Dolphin AC (1998) Mechanisms of modulation of voltage-dependent calcium channels by G proteins. J Physiol (Lond) 506:3-11.
10. Dove LS, Abbott LC, Griffith WH (1998) Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice. J Neurosci 18:7687-7699.
11. Doyle J, Ren X, Lennon G, Stubbs L (1997) Mutations in the Cacn11a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice. Mamm Genome 8:113-120.
12. 2+ channels in mammalian central neurons. Trends Neurosci 18:89-98.
13. Fletcher CF, Lutz CM, O'Sullivan TN, Shaughnessy Jr JD, Hawkes R, Frankel WN, Copeland NG, Jenkins NA (1996) Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 15:607-617.
14. Helekar SA, Noebels JL (1994) Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering. J Neurophysiol 1994 71:1-10.
15. B receptor activation in absence seizures of lethargic (lh/lh) mice. Science 257:398-401.
16. Iwasaki S, Takahashi T (1998) Developmental changes in calcium channel types mediating synaptic transmission in rat auditory brainstem. J Physiol (Lond) 509:419-423.
17. Lorenzon NM, Lutz CM, Frankel WN, Beam KG (1998) Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner. J Neurosci 18:4482-4489.
18. McEnery MW, Copeland TD, Vance CL (1998) Altered expression and assembly of N-type calcium channel alpha 1B and beta subunits in epileptic lethargic (lh/lh) mouse. J Biol Chem 273:21435-21438.
19. Mintz IM, Sabatini BL, Regehr WG (1995) Calcium control of transmitter release at a cerebellar synapse. Neuron 15:675-688.
20. Noebels JL (1984) Isolating single genes of the inherited epilepsies. Ann Neurol 16:18-21.
21. Nochels JL, Sidman RL (1979) Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering. Science 204:1334-1336.
22. 2+ channel defects in migraine, ataxia and epilepsy. Trends Pharmacol Sci 19:121-127.
23. Poncer JC, McKinney RA, Gahwiler BH, Thompson SM (1997) Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron 18:463-472.
24. Qian J, Saggau P (1999) Modulation of transmitter release by action potential duration at the hippocampal CA3-CA1 synapse. J. Neurophysiol 81:288-298.
25. Qian J, Colmers WF, Saggau P (1997) Inhibition of synaptic transmission by neuropeptide Y in rat hippocampal area CA1: modulation of presynaptic Ca entry. J Neurosci 17:8169-8177.
26. Rhyu IJ, Abbott LC, Walker DB, Sotelo C (1999) An ultrastructural study of granule cell/Purkinje cell synapses in tottering (tg/tg), leaner (tg(la)/tg(la)) and compound heterozygous tottering/leaner (tg/tg(la)) mice. Neurosciencc 90:717-728.
27. Roche JP, Anantharam V, Treistman SN (1995) Abolition of G protein inhibition of alpha IA and alpha IB calcium channels by co-expression of the beta 3 subunit. FEBS Lett 371:43-46.
28. Sheng ZH, Rettig J, Cook T, Catterall WA (1996) Calcium-dependent interaction of N-type calcium channels with the synaptic core complex. Nature 379:451-454.
29. Tanaka O, Sakagami H, Kondo H (1995) Localization of mRNAs of voltage-dependent Ca(2+)-channels: four subtypes of alpha 1- and beta-subunits in developing and mature rat brain. Brain Res Mol Brain Res 30:1-16.
30. Wakamori M, Yamazaki K, Matsunodaira H, Teramoto T, Tanaka I, Niidome T, Sawada K, Nishizawa Y, Sekiguchi N, Mori E, Mori Y, Imoto K (1998) Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel. J Biol Chem 273:34857-34867.
31. 2+ channels: role in channel function. Trends Neurosci 21:148-154.
32. 2+ channel activation. J Biol Chem 274:12383-12390.
33. 2+ channels in supporting hippocampal synaptic transmission. Science 264:107-111.
34. Wu LG, Saggau P (1994) Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus. Neuron 12:1139-1148.
35. B receptor-mediated presynaptic inhibition in guinea pig hippocampus is caused by reduction of presynaptic Ca influx. J. Physiol (Lond) 485:649-657.
36. 2+ currents evoke transmitter release at a rat central synapse. Proc Natl Acad Sci USA 95:4720-4725.
37. Wu LG, Westenbrock RE, Borst JGG, Catterall WA, Sakmann B (1999) Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses. J Neurosci 19:726-736.