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Volumn , Issue , 2008, Pages 63-73

Integrins in angiogenesis

Author keywords

Angiogenesis; Apoptosis; Cell Invasion; Extracellular Matrix; Integrin

Indexed keywords


EID: 79952752543     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-71518-6_6     Document Type: Chapter
Times cited : (2)

References (142)
  • 1
    • 0030448814 scopus 로고    scopus 로고
    • Blood vessel formation: What is its molecular basis?
    • Folkman J, D'Amore PA. Blood vessel formation: what is its molecular basis? Cell 1996;87(7):1153-5.
    • (1996) Cell , vol.87 , Issue.7 , pp. 1153-1155
    • Folkman, J.1    D'Amore, P.A.2
  • 2
    • 0024315634 scopus 로고
    • Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: Role of extracellular matrix
    • Ingber DE, Folkman J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. The Journal of cell biology 1989;109(1):317-30.
    • (1989) The Journal of Cell Biology , vol.109 , Issue.1 , pp. 317-330
    • Ingber, D.E.1    Folkman, J.2
  • 3
    • 0020631281 scopus 로고
    • Basement membrane collagen: Degradation by migrating endothelial cells
    • Kalebic T, Garbisa S, Glaser B, Liotta LA. Basement membrane collagen: degradation by migrating endothelial cells. Science 1983;221(4607):281-3.
    • (1983) Science , vol.221 , Issue.4607 , pp. 281-283
    • Kalebic, T.1    Garbisa, S.2    Glaser, B.3    Liotta, L.A.4
  • 4
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69(1):11-25.
    • (1992) Cell , vol.69 , Issue.1 , pp. 11-25
    • Hynes, R.O.1
  • 5
    • 0034715923 scopus 로고    scopus 로고
    • Focal adhesions: A nexus for intracel-lular signaling and cytoskeletal dynamics
    • Sastry SK, Burridge K. Focal adhesions: a nexus for intracel-lular signaling and cytoskeletal dynamics. Experimental cell research 2000;261(1):25-36.
    • (2000) Experimental Cell Research , vol.261 , Issue.1 , pp. 25-36
    • Sastry, S.K.1    Burridge, K.2
  • 8
    • 0033554723 scopus 로고    scopus 로고
    • Id1 and id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
    • Lyden D, Young AZ, Zagzag D, et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 1999;401(6754):670-7.
    • (1999) Nature , vol.401 , Issue.6754 , pp. 670-677
    • Lyden, D.1    Young, A.Z.2    Zagzag, D.3
  • 11
    • 0033843942 scopus 로고    scopus 로고
    • Regulation of angiogen-esis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin
    • Kim S, Bell K, Mousa SA, Varner JA. Regulation of angiogen-esis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin. The American journal of pathology 2000;156(4):1345-62.
    • (2000) The American Journal of Pathology , vol.156 , Issue.4 , pp. 1345-1362
    • Kim, S.1    Bell, K.2    Mousa, S.A.3    Varner, J.A.4
  • 13
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994;264(5158): 569-71.
    • (1994) Science , vol.264 , Issue.5158 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 14
    • 20444483652 scopus 로고    scopus 로고
    • Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation
    • Garmy-Susini B, Jin H, Zhu Y, Sung RJ, Hwang R, Varner J. Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation. The Journal of clinical investigation 2005;115(6): 1542-51.
    • (2005) The Journal of Clinical Investigation , vol.115 , Issue.6 , pp. 1542-1551
    • Garmy-Susini, B.1    Jin, H.2    Zhu, Y.3    Sung, R.J.4    Hwang, R.5    Varner, J.6
  • 15
    • 0141725517 scopus 로고    scopus 로고
    • Endothelial expression of the alpha6beta4 integrin is negatively regulated during angiogenesis
    • Hiran TS, Mazurkiewicz JE, Kreienberg P, Rice FL, LaFlamme SE. Endothelial expression of the alpha6beta4 integrin is negatively regulated during angiogenesis. Journal of cell science 2003;116(Pt 18):3771-81.
    • (2003) Journal of Cell Science , vol.116 , Issue.PART 18 , pp. 3771-3781
    • Hiran, T.S.1    Mazurkiewicz, J.E.2    Kreienberg, P.3    Rice, F.L.4    LaFlamme, S.E.5
  • 16
    • 0028171068 scopus 로고
    • The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin
    • Yokosaki Y, Palmer EL, Prieto AL, et al. The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin. The Journal of biological chemistry 1994;269(43):26691-6.
    • (1994) The Journal of Biological Chemistry , vol.269 , Issue.43 , pp. 26691-26696
    • Yokosaki, Y.1    Palmer, E.L.2    Prieto, A.L.3
  • 17
    • 0029946457 scopus 로고    scopus 로고
    • Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin
    • Smith LL, Cheung HK, Ling LE, et al. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by alpha9beta1 integrin. The Journal of biological chemistry 1996;271(45):28485-91.
    • (1996) The Journal of Biological Chemistry , vol.271 , Issue.45 , pp. 28485-28491
    • Smith, L.L.1    Cheung, H.K.2    Ling, L.E.3
  • 18
    • 0033583322 scopus 로고    scopus 로고
    • The integrin alpha-9beta1 mediates adhesion to activated endothelial cells and transendothelial neutrophil migration through interaction with vascular cell adhesion molecule-1
    • Taooka Y, Chen J, Yednock T, Sheppard D. The integrin alpha-9beta1 mediates adhesion to activated endothelial cells and transendothelial neutrophil migration through interaction with vascular cell adhesion molecule-1. The Journal of cell biology 1999;145(2):413-20.
    • (1999) The Journal of Cell Biology , vol.145 , Issue.2 , pp. 413-420
    • Taooka, Y.1    Chen, J.2    Yednock, T.3    Sheppard, D.4
  • 19
    • 0033948027 scopus 로고    scopus 로고
    • Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1
    • Huang XZ, Wu JF, Ferrando R, et al. Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1. Molecular and cellular biology 2000;20(14):5208-15.
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5208-5215
    • Huang, X.Z.1    Wu, J.F.2    Ferrando, R.3
  • 20
    • 0035983579 scopus 로고    scopus 로고
    • Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies
    • Francis SE, Goh KL, Hodivala-Dilke K, et al. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):927-33.
    • (2002) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.22 , Issue.6 , pp. 927-933
    • Francis, S.E.1    Goh, K.L.2    Hodivala-Dilke, K.3
  • 21
    • 0027371908 scopus 로고
    • Embryonic mesodermal defects in alpha 5 integrin-deficient mice
    • Yang JT, Rayburn H, Hynes RO. Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development (Cambridge, England) 1993;119(4):1093-105.
    • (1993) Development (Cambridge, England) , vol.119 , Issue.4 , pp. 1093-1105
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3
  • 22
    • 0032514841 scopus 로고    scopus 로고
    • Extensive vascu-logenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins
    • Bader BL, Rayburn H, Crowley D, Hynes RO. Extensive vascu-logenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell 1998;95(4):507-19.
    • (1998) Cell , vol.95 , Issue.4 , pp. 507-519
    • Bader, B.L.1    Rayburn, H.2    Crowley, D.3    Hynes, R.O.4
  • 24
    • 0032590042 scopus 로고    scopus 로고
    • Beta3-integrin-deficient mice are a model for glanzmann thrombas-thenia showing placental defects and reduced survival
    • Hodivala-Dilke KM, McHugh KP, Tsakiris DA, et al. Beta3-integrin- deficient mice are a model for Glanzmann thrombas-thenia showing placental defects and reduced survival. The Journal of clinical investigation 1999;103(2):229-38.
    • (1999) The Journal of Clinical Investigation , vol.103 , Issue.2 , pp. 229-238
    • Hodivala-Dilke, K.M.1    McHugh, K.P.2    Tsakiris, D.A.3
  • 26
    • 15844376477 scopus 로고    scopus 로고
    • Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin
    • Huang XZ, Wu JF, Cass D, et al. Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin. The Journal of cell biology 1996;133(4):921-8.
    • (1996) The Journal of Cell Biology , vol.133 , Issue.4 , pp. 921-928
    • Huang, X.Z.1    Wu, J.F.2    Cass, D.3
  • 27
    • 0036152857 scopus 로고    scopus 로고
    • Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins
    • Reynolds LE, Wyder L, Lively JC, et al. Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nature medicine 2002;8(1):27-34.
    • (2002) Nature Medicine , vol.8 , Issue.1 , pp. 27-34
    • Reynolds, L.E.1    Wyder, L.2    Lively, J.C.3
  • 28
    • 20044380507 scopus 로고    scopus 로고
    • Accelerated re-epithe-lialization in beta3-integrin-deficientmice is associated with enhanced TGF-beta1 signaling
    • Reynolds LE, Conti FJ, Lucas M, et al. Accelerated re-epithe-lialization in beta3-integrin-deficientmice is associated with enhanced TGF-beta1 signaling. Nature medicine 2005;11(2): 167-74.
    • (2005) Nature Medicine , vol.11 , Issue.2 , pp. 167-174
    • Reynolds, L.E.1    Conti, F.J.2    Lucas, M.3
  • 30
    • 84885750775 scopus 로고    scopus 로고
    • Cooperation between VEGF and {beta}3 integrin during cardiac vascular development
    • Weis SM, Lindquist JN, Barnes LA, et al. Cooperation between VEGF and {beta}3 integrin during cardiac vascular development. Blood 2006.
    • (2006) Blood
    • Weis, S.M.1    Lindquist, J.N.2    Barnes, L.A.3
  • 31
    • 0030814976 scopus 로고    scopus 로고
    • Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF
    • Schneller M, Vuori K, Ruoslahti E. Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF. The EMBO journal 1997;16(18):5600-7.
    • (1997) The EMBO Journal , vol.16 , Issue.18 , pp. 5600-5607
    • Schneller, M.1    Vuori, K.2    Ruoslahti, E.3
  • 32
    • 0034704174 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain
    • Borges E, Jan Y, Ruoslahti E. Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain. The Journal of biological chemistry 2000;275(51):39867-73.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.51 , pp. 39867-39873
    • Borges, E.1    Jan, Y.2    Ruoslahti, E.3
  • 33
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metallopro-teinase-9 triggers the angiogenic switch during carcinogenesis
    • Bergers G, Brekken R, McMahon G, et al. Matrix metallopro-teinase-9 triggers the angiogenic switch during carcinogenesis. Nature cell biology 2000;2(10):737-44.
    • (2000) Nature Cell Biology , vol.2 , Issue.10 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3
  • 34
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
    • Brooks PC, Stromblad S, Sanders LC, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996;85(5): 683-93.
    • (1996) Cell , vol.85 , Issue.5 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3
  • 35
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
    • Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 1998;92(3):391-400.
    • (1998) Cell , vol.92 , Issue.3 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalscha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 36
    • 0035802109 scopus 로고    scopus 로고
    • Proteolytic exposure of a cryptic site within collagen type IV is required for angio-genesis and tumor growth in vivo
    • Xu J, Rodriguez D, Petitclerc E, et al. Proteolytic exposure of a cryptic site within collagen type IV is required for angio-genesis and tumor growth in vivo. The Journal of cell biology 2001;154(5):1069-79.
    • (2001) The Journal of Cell Biology , vol.154 , Issue.5 , pp. 1069-1079
    • Xu, J.1    Rodriguez, D.2    Petitclerc, E.3
  • 37
    • 0029965462 scopus 로고    scopus 로고
    • Transient functional expression of alphaVbeta 3 on vascular cells during wound repair
    • Clark RA, Tonnesen MG, Gailit J, Cheresh DA. Transient functional expression of alphaVbeta 3 on vascular cells during wound repair. The American journal of pathology 1996;148(5): 1407-21.
    • (1996) The American Journal of Pathology , vol.148 , Issue.5 , pp. 1407-1421
    • Clark, R.A.1    Tonnesen, M.G.2    Gailit, J.3    Cheresh, D.A.4
  • 38
    • 0024208660 scopus 로고
    • Pathogenesis of tumor stroma generation: A critical role for leaky blood vessels and fibrin deposition
    • Nagy JA, Brown LF, Senger DR, et al. Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition. Biochimica et biophysica acta 1989;948(3): 305-26.
    • (1989) Biochimica et Biophysica Acta , vol.948 , Issue.3 , pp. 305-326
    • Nagy, J.A.1    Brown, L.F.2    Senger, D.R.3
  • 40
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. The New England journal of medicine 1986;315(26):1650-9.
    • (1986) The New England Journal of Medicine , vol.315 , Issue.26 , pp. 1650-1659
    • Dvorak, H.F.1
  • 41
    • 0033847194 scopus 로고    scopus 로고
    • RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins
    • Bayless KJ, Salazar R, Davis GE. RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins. The American journal of pathology 2000;156(5):1673-83.
    • (2000) The American Journal of Pathology , vol.156 , Issue.5 , pp. 1673-1683
    • Bayless, K.J.1    Salazar, R.2    Davis, G.E.3
  • 44
    • 0036142782 scopus 로고    scopus 로고
    • The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
    • Senger DR, Perruzzi CA, Streit M, Koteliansky VE, de Foug-erolles AR, Detmar M. The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. The American journal of pathology 2002;160(1): 195-204.
    • (2002) The American Journal of Pathology , vol.160 , Issue.1 , pp. 195-204
    • Senger, D.R.1    Perruzzi, C.A.2    Streit, M.3    Koteliansky, V.E.4    De Foug-Erolles, A.R.5    Detmar, M.6
  • 45
    • 0032498640 scopus 로고    scopus 로고
    • Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
    • Eliceiri BP, Klemke R, Stromblad S, Cheresh DA. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. The Journal of cell biology 1998;140(5):1255-63.
    • (1998) The Journal of Cell Biology , vol.140 , Issue.5 , pp. 1255-1263
    • Eliceiri, B.P.1    Klemke, R.2    Stromblad, S.3    Cheresh, D.A.4
  • 48
    • 0030038229 scopus 로고    scopus 로고
    • Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
    • Stromblad S, Becker JC, Yebra M, Brooks PC, Cheresh DA. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. The Journal of clinical investigation 1996;98(2):426-33.
    • (1996) The Journal of Clinical Investigation , vol.98 , Issue.2 , pp. 426-433
    • Stromblad, S.1    Becker, J.C.2    Yebra, M.3    Brooks, P.C.4    Cheresh, D.A.5
  • 50
    • 0029925079 scopus 로고    scopus 로고
    • Subcutaneous injection of a cyclic peptide antagonist of vitro-nectin receptor-type integrins inhibits retinal neovascularization
    • Hammes HP, Brownlee M, Jonczyk A, Sutter A, Preissner KT. Subcutaneous injection of a cyclic peptide antagonist of vitro-nectin receptor-type integrins inhibits retinal neovascularization. Nature medicine 1996;2(5):529-33.
    • (1996) Nature Medicine , vol.2 , Issue.5 , pp. 529-533
    • Hammes, H.P.1    Brownlee, M.2    Jonczyk, A.3    Sutter, A.4    Preissner, K.T.5
  • 51
    • 0035943604 scopus 로고    scopus 로고
    • Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis
    • Maeshima Y, Yerramalla UL, Dhanabal M, et al. Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis. The Journal of biological chemistry 2001;276(34):31959-68.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.34 , pp. 31959-31968
    • Maeshima, Y.1    Yerramalla, U.L.2    Dhanabal, M.3
  • 52
    • 0036796781 scopus 로고    scopus 로고
    • Get a ligand, get a life: Integrins, signaling and cell survival
    • Stupack DG, Cheresh DA. Get a ligand, get a life: integrins, signaling and cell survival. Journal of cell science 2002;115(Pt 19):3729-38.
    • (2002) Journal of Cell Science , vol.115 , Issue.PART 19 , pp. 3729-3738
    • Stupack, D.G.1    Cheresh, D.A.2
  • 53
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A question of life or death
    • Mehlen P, Puisieux A. Metastasis: a question of life or death. Nature reviews 2006;6(6):449-58.
    • (2006) Nature Reviews , vol.6 , Issue.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 54
    • 30144434107 scopus 로고    scopus 로고
    • Potentiation of neuroblas-toma metastasis by loss of caspase-8
    • Stupack DG, Teitz T, Potter MD, et al. Potentiation of neuroblas-toma metastasis by loss of caspase-8. Nature 2006;439(7072): 95-9.
    • (2006) Nature , vol.439 , Issue.7072 , pp. 95-99
    • Stupack, D.G.1    Teitz, T.2    Potter, M.D.3
  • 55
    • 0034604650 scopus 로고    scopus 로고
    • Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties
    • Maeshima Y, Colorado PC, Kalluri R. Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. The Journal of biological chemistry 2000;275(31):23745-50.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.31 , pp. 23745-23750
    • Maeshima, Y.1    Colorado, P.C.2    Kalluri, R.3
  • 56
    • 0033551899 scopus 로고    scopus 로고
    • Integrin signaling
    • Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999;285(5430):1028-32.
    • (1999) Science , vol.285 , Issue.5430 , pp. 1028-1032
    • Giancotti, F.G.1    Ruoslahti, E.2
  • 58
    • 1542328956 scopus 로고    scopus 로고
    • A mitochondrial protein, bit1, mediates apoptosis regulated by integrins and groucho/TLE corepressors
    • Jan Y, Matter M, Pai JT, et al. A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell 2004;116(5):751-62.
    • (2004) Cell , vol.116 , Issue.5 , pp. 751-762
    • Jan, Y.1    Matter, M.2    Pai, J.T.3
  • 63
    • 0037134486 scopus 로고    scopus 로고
    • Loss of p53 compensates for alpha v-integrin function in retinal neovascularization
    • Stromblad S, Fotedar A, Brickner H, et al. Loss of p53 compensates for alpha v-integrin function in retinal neovascularization. The Journal of biological chemistry 2002;277(16): 13371-4.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.16 , pp. 13371-13374
    • Stromblad, S.1    Fotedar, A.2    Brickner, H.3
  • 64
    • 10744223801 scopus 로고    scopus 로고
    • Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin
    • Hamano Y, Zeisberg M, Sugimoto H, et al. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer cell 2003;3(6):589-601.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 589-601
    • Hamano, Y.1    Zeisberg, M.2    Sugimoto, H.3
  • 65
    • 0035805614 scopus 로고    scopus 로고
    • Identification of the anti-angiogenic site within vascular basement membranederived tumstatin
    • Maeshima Y, Manfredi M, Reimer C, et al. Identification of the anti-angiogenic site within vascular basement membranederived tumstatin. The Journal of biological chemistry 2001;276(18):15240-8.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.18 , pp. 15240-15248
    • Maeshima, Y.1    Manfredi, M.2    Reimer, C.3
  • 67
    • 0037016498 scopus 로고    scopus 로고
    • Tumstatin, an endothelial cell-specific inhibitor of protein synthesis
    • Maeshima Y, Sudhakar A, Lively JC, et al. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science 2002;295(5552):140-3.
    • (2002) Science , vol.295 , Issue.5552 , pp. 140-143
    • Maeshima, Y.1    Sudhakar, A.2    Lively, J.C.3
  • 68
    • 23044451988 scopus 로고    scopus 로고
    • Integrins as a distinct subtype of dependence receptors
    • Stupack DG. Integrins as a distinct subtype of dependence receptors. Cell death and differentiation 2005;12(8):1021-30.
    • (2005) Cell Death and Differentiation , vol.12 , Issue.8 , pp. 1021-1030
    • Stupack, D.G.1
  • 69
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for src kinases during VEGF-induced angiogenesis and vascular permeability
    • Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability. Molecular Cell 1999;4(6):915-24.
    • (1999) Molecular Cell , vol.4 , Issue.6 , pp. 915-924
    • Eliceiri, B.P.1    Paul, R.2    Schwartzberg, P.L.3    Hood, J.D.4    Leng, J.5    Cheresh, D.A.6
  • 70
    • 0038724937 scopus 로고    scopus 로고
    • Role of raf in vascular protection from distinct apoptotic stimuli
    • Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. Role of Raf in vascular protection from distinct apoptotic stimuli. Science 2003;301(5629):94-6.
    • (2003) Science , vol.301 , Issue.5629 , pp. 94-96
    • Alavi, A.1    Hood, J.D.2    Frausto, R.3    Stupack, D.G.4    Cheresh, D.A.5
  • 71
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • Hood JD, Bednarski M, Frausto R, et al. Tumor regression by targeted gene delivery to the neovasculature. Science 2002;296(5577): 2404-7.
    • (2002) Science , vol.296 , Issue.5577 , pp. 2404-2407
    • Hood, J.D.1    Bednarski, M.2    Frausto, R.3
  • 72
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes: Structure, assembly and role in tumour angiogenesis
    • Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nature reviews 2003;3(6):422-33.
    • (2003) Nature Reviews , vol.3 , Issue.6 , pp. 422-433
    • Kalluri, R.1
  • 73
    • 0034194237 scopus 로고    scopus 로고
    • Anti-angiogenic cues from vascular basement membrane collagen
    • Colorado PC, Torre A, Kamphaus G, et al. Anti-angiogenic cues from vascular basement membrane collagen. Cancer research 2000;60(9):2520-6.
    • (2000) Cancer Research , vol.60 , Issue.9 , pp. 2520-2526
    • Colorado, P.C.1    Torre, A.2    Kamphaus, G.3
  • 74
    • 0034307327 scopus 로고    scopus 로고
    • Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase
    • Kim YM, Jang JW, Lee OH, et al. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer research 2000;60(19):5410-3.
    • (2000) Cancer Research , vol.60 , Issue.19 , pp. 5410-5413
    • Kim, Y.M.1    Jang, J.W.2    Lee, O.H.3
  • 75
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly MS, Boehm T, Shing Y, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997;88(2):277-85.
    • (1997) Cell , vol.88 , Issue.2 , pp. 277-285
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 76
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y, et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994;79(2):315-28.
    • (1994) Cell , vol.79 , Issue.2 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 77
    • 0033979905 scopus 로고    scopus 로고
    • Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth
    • Kamphaus GD, Colorado PC, Panka DJ, et al. Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. The Journal of biological chemistry 2000;275(2):1209-15.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.2 , pp. 1209-1215
    • Kamphaus, G.D.1    Colorado, P.C.2    Panka, D.J.3
  • 78
    • 0034677760 scopus 로고    scopus 로고
    • New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo
    • Petitclerc E, Boutaud A, Prestayko A, et al. New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo. The Journal of biological chemistry 2000;275(11): 8051-61.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 8051-8061
    • Petitclerc, E.1    Boutaud, A.2    Prestayko, A.3
  • 79
    • 20144379162 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis
    • Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer research 2005;65(10):3967-79.
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 3967-3979
    • Nyberg, P.1    Xie, L.2    Kalluri, R.3
  • 80
    • 0037008721 scopus 로고    scopus 로고
    • Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1
    • Kim YM, Hwang S, Kim YM, et al. Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. The Journal of biological chemistry 2002;277(31):27872-9.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.31 , pp. 27872-27879
    • Kim, Y.M.1    Hwang, S.2    Kim, Y.M.3
  • 82
    • 0034672644 scopus 로고    scopus 로고
    • Generation and degradation of human endostatin proteins by various proteinases
    • Ferreras M, Felbor U, Lenhard T, Olsen BR, Delaisse J. Generation and degradation of human endostatin proteins by various proteinases. FEBS letters 2000;486(3):247-51.
    • (2000) FEBS Letters , vol.486 , Issue.3 , pp. 247-251
    • Ferreras, M.1    Felbor, U.2    Lenhard, T.3    Olsen, B.R.4    Delaisse, J.5
  • 83
    • 0034647922 scopus 로고    scopus 로고
    • Distinct antitumor properties of a type IV collagen domain derived from basement membrane
    • Maeshima Y, Colorado PC, Torre A, et al. Distinct antitumor properties of a type IV collagen domain derived from basement membrane. The Journal of biological chemistry 2000;275(28):21340-8.
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.28 , pp. 21340-21348
    • Maeshima, Y.1    Colorado, P.C.2    Torre, A.3
  • 84
    • 0036734093 scopus 로고    scopus 로고
    • A reevaluation of integrins as regulators of angiogenesis
    • Hynes RO. A reevaluation of integrins as regulators of angiogenesis. Nature medicine 2002;8(9):918-21.
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 918-921
    • Hynes, R.O.1
  • 86
    • 0033575658 scopus 로고    scopus 로고
    • Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding
    • Yamaguchi N, Anand-Apte B, Lee M, et al. Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. The EMBO journal 1999;18(16): 4414-23.
    • (1999) The EMBO Journal , vol.18 , Issue.16 , pp. 4414-4423
    • Yamaguchi, N.1    Anand-Apte, B.2    Lee, M.3
  • 88
    • 0037157106 scopus 로고    scopus 로고
    • Endostatin binds to the catalytic domain of matrix metalloproteinase-2
    • Lee SJ, Jang JW, Kim YM, et al. Endostatin binds to the catalytic domain of matrix metalloproteinase-2. FEBS letters 2002;519 (1-3):147-52.
    • (2002) FEBS Letters , vol.519 , Issue.1-3 , pp. 147-152
    • Lee, S.J.1    Jang, J.W.2    Kim, Y.M.3
  • 89
    • 0037590989 scopus 로고    scopus 로고
    • Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2,-9, and-13
    • Nyberg P, Heikkila P, Sorsa T, et al. Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2,-9, and-13. The Journal of biological chemistry 2003;278(25):22404-11.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22404-22411
    • Nyberg, P.1    Heikkila, P.2    Sorsa, T.3
  • 91
    • 0034088799 scopus 로고    scopus 로고
    • Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase
    • Deryugina EI, Bourdon MA, Jungwirth K, Smith JW, Strongin AY. Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase. International journal of cancer 2000;86(1):15-23.
    • (2000) International Journal of Cancer , vol.86 , Issue.1 , pp. 15-23
    • Deryugina, E.I.1    Bourdon, M.A.2    Jungwirth, K.3    Smith, J.W.4    Strongin, A.Y.5
  • 92
    • 0242405617 scopus 로고    scopus 로고
    • Endothelial-pericyte interactions in angiogenesis
    • Gerhardt H, Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell and tissue research 2003;314(1):15-23.
    • (2003) Cell and Tissue Research , vol.314 , Issue.1 , pp. 15-23
    • Gerhardt, H.1    Betsholtz, C.2
  • 94
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellstrom M, Kalen M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development (Cambridge, England) 1999;126(14):3047-55.
    • (1999) Development (Cambridge, England) , vol.126 , Issue.14 , pp. 3047-3055
    • Hellstrom, M.1    Kalen, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 95
    • 0035972251 scopus 로고    scopus 로고
    • Lack of pericytes leads to endothelial Hyperplasia and abnormal vascular morphogenesis
    • Hellstrom M, Gerhardt H, Kalen M, et al. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. The Journal of cell biology 2001;153(3):543-53.
    • (2001) The Journal of Cell Biology , vol.153 , Issue.3 , pp. 543-553
    • Hellstrom, M.1    Gerhardt, H.2    Kalen, M.3
  • 96
    • 0026093380 scopus 로고
    • Connective tissue production by vascular smooth muscle in development and disease
    • Mecham RP, Stenmark KR, Parks WC. Connective tissue production by vascular smooth muscle in development and disease. Chest 1991;99(3 Suppl):43S-7S.
    • (1991) Chest , vol.99 , Issue.3 SUPPL.
    • Mecham, R.P.1    Stenmark, K.R.2    Parks, W.C.3
  • 97
    • 0026350710 scopus 로고
    • Extracellular matrix gene expression by human endothelial and smooth muscle cells
    • Tan EM, Glassberg E, Olsen DR, et al. Extracellular matrix gene expression by human endothelial and smooth muscle cells. Matrix (Stuttgart, Germany) 1991;11(6):380-7.
    • (1991) Matrix (Stuttgart, Germany) , vol.11 , Issue.6 , pp. 380-387
    • Tan, E.M.1    Glassberg, E.2    Olsen, D.R.3
  • 98
    • 33646027901 scopus 로고    scopus 로고
    • Defective blood vessel development and pericyte/pvSMC distribution in alpha 4 integrin-deficient mouse embryos
    • Grazioli A, Alves CS, Konstantopoulos K, Yang JT. Defective blood vessel development and pericyte/pvSMC distribution in alpha 4 integrin-deficient mouse embryos. Developmental biology 2006;293(1):165-77.
    • (2006) Developmental Biology , vol.293 , Issue.1 , pp. 165-177
    • Grazioli, A.1    Alves, C.S.2    Konstantopoulos, K.3    Yang, J.T.4
  • 99
    • 0041976960 scopus 로고    scopus 로고
    • Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration
    • Goldfinger LE, Han J, Kiosses WB, Howe AK, Ginsberg MH. Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. The Journal of cell biology 2003;162(4):731-41.
    • (2003) The Journal of Cell Biology , vol.162 , Issue.4 , pp. 731-741
    • Goldfinger, L.E.1    Han, J.2    Kiosses, W.B.3    Howe, A.K.4    Ginsberg, M.H.5
  • 100
    • 0037182578 scopus 로고    scopus 로고
    • Dual functions of [alpha]4[beta]1 integrin in epicardial development: Initial migration and long-term attachment
    • Sengbusch JK, He W, Pinco KA, Yang JT. Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment. The Journal of cell biology 2002;157(5):873-82.
    • (2002) The Journal of Cell Biology , vol.157 , Issue.5 , pp. 873-882
    • Sengbusch, J.K.1    He, W.2    Pinco, K.A.3    Yang, J.T.4
  • 101
    • 0027169160 scopus 로고
    • Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin
    • Kassner PD, Hemler ME. Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin. The Journal of experimental medicine 1993;178(2):649-60.
    • (1993) The Journal of Experimental Medicine , vol.178 , Issue.2 , pp. 649-660
    • Kassner, P.D.1    Hemler, M.E.2
  • 102
    • 0036708599 scopus 로고    scopus 로고
    • Alpha4beta1 integrin regulates lamellipodia protrusion via a focal complex/focal adhesion-independent mechanism
    • Pinco KA, He W, Yang JT. alpha4beta1 integrin regulates lamellipodia protrusion via a focal complex/focal adhesion-independent mechanism. Molecular biology of the cell 2002;13(9):3203-17.
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.9 , pp. 3203-3217
    • Pinco, K.A.1    He, W.2    Yang, J.T.3
  • 103
    • 17344366888 scopus 로고    scopus 로고
    • An alpha4 integrin-paxillin-arf-GAP complex restricts rac activation to the leading edge of migrating cells
    • Nishiya N, Kiosses WB, Han J, Ginsberg MH. An alpha4 integrin-paxillin- Arf-GAP complex restricts Rac activation to the leading edge of migrating cells. Nature cell biology 2005;7(4):343-52.
    • (2005) Nature Cell Biology , vol.7 , Issue.4 , pp. 343-352
    • Nishiya, N.1    Kiosses, W.B.2    Han, J.3    Ginsberg, M.H.4
  • 105
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn L, Hession C, Tizard R, et al. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 1989;59(6):1203-11.
    • (1989) Cell , vol.59 , Issue.6 , pp. 1203-1211
    • Osborn, L.1    Hession, C.2    Tizard, R.3
  • 106
    • 0025161990 scopus 로고
    • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
    • Elices MJ, Osborn L, Takada Y, et al. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 1990;60(4):577-84.
    • (1990) Cell , vol.60 , Issue.4 , pp. 577-584
    • Elices, M.J.1    Osborn, L.2    Takada, Y.3
  • 107
    • 0025124607 scopus 로고
    • Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1
    • Guan JL, Hynes RO. Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell 1990;60(1):53-61.
    • (1990) Cell , vol.60 , Issue.1 , pp. 53-61
    • Guan, J.L.1    Hynes, R.O.2
  • 108
    • 0038386470 scopus 로고    scopus 로고
    • Role of bone marrow-derived cells in tumor angiogenesis and treatment
    • Jain RK, Duda DG. Role of bone marrow-derived cells in tumor angiogenesis and treatment. Cancer cell 2003;3(6):515-6.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 515-516
    • Jain, R.K.1    Duda, D.G.2
  • 109
    • 4043052443 scopus 로고    scopus 로고
    • Administration of CD34+ cells after stroke enhances neurogenesis via angiogen-esis in a mouse model
    • Taguchi A, Soma T, Tanaka H, et al. Administration of CD34+ cells after stroke enhances neurogenesis via angiogen-esis in a mouse model. The Journal of clinical investigation 2004;114(3):330-8.
    • (2004) The Journal of Clinical Investigation , vol.114 , Issue.3 , pp. 330-338
    • Taguchi, A.1    Soma, T.2    Tanaka, H.3
  • 110
    • 11144355004 scopus 로고    scopus 로고
    • VEGF-A stimulates lym-phangiogenesis and hemangiogenesis in inflammatory neovas-cularization via macrophage recruitment
    • Cursiefen C, Chen L, Borges LP, et al. VEGF-A stimulates lym-phangiogenesis and hemangiogenesis in inflammatory neovas-cularization via macrophage recruitment. The Journal of clinical investigation 2004;113(7):1040-50.
    • (2004) The Journal of Clinical Investigation , vol.113 , Issue.7 , pp. 1040-1050
    • Cursiefen, C.1    Chen, L.2    Borges, L.P.3
  • 111
    • 11144356370 scopus 로고    scopus 로고
    • CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A
    • Scapini P, Morini M, Tecchio C, et al. CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A. J Immunol 2004;172(8):5034-40.
    • (2004) J Immunol , vol.172 , Issue.8 , pp. 5034-5040
    • Scapini, P.1    Morini, M.2    Tecchio, C.3
  • 112
    • 33644555196 scopus 로고    scopus 로고
    • Integrin alpha4beta1 promotes monocyte trafficking and angiogenesis in tumors
    • Jin H, Su J, Garmy-Susini B, Kleeman J, Varner J. Integrin alpha4beta1 promotes monocyte trafficking and angiogenesis in tumors. Cancer research 2006;66(4):2146-52.
    • (2006) Cancer Research , vol.66 , Issue.4 , pp. 2146-2152
    • Jin, H.1    Su, J.2    Garmy-Susini, B.3    Kleeman, J.4    Varner, J.5
  • 113
    • 33644650332 scopus 로고    scopus 로고
    • A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovascula-ture
    • Jin H, Aiyer A, Su J, et al. A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovascula-ture. The Journal of clinical investigation 2006;116(3):652-62.
    • (2006) The Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 652-662
    • Jin, H.1    Aiyer, A.2    Su, J.3
  • 114
    • 0142195911 scopus 로고    scopus 로고
    • Effect of angiogen-esis inhibition by id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors
    • Ruzinova MB, Schoer RA, Gerald W, et al. Effect of angiogen-esis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer cell 2003;4(4):277-89.
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 277-289
    • Ruzinova, M.B.1    Schoer, R.A.2    Gerald, W.3
  • 115
    • 16244373354 scopus 로고    scopus 로고
    • EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy
    • Dietrich J, Lacagnina M, Gass D, et al. EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy. Nature medicine 2005;11(3):277-83.
    • (2005) Nature Medicine , vol.11 , Issue.3 , pp. 277-283
    • Dietrich, J.1    Lacagnina, M.2    Gass, D.3
  • 117
    • 0033866240 scopus 로고    scopus 로고
    • In vivo therapy of malignant melanoma by means of antagonists of alphav integrins
    • Mitjans F, Meyer T, Fittschen C, et al. In vivo therapy of malignant melanoma by means of antagonists of alphav integrins. International journal of cancer 2000;87(5):716-23.
    • (2000) International Journal of Cancer , vol.87 , Issue.5 , pp. 716-723
    • Mitjans, F.1    Meyer, T.2    Fittschen, C.3
  • 118
    • 0034283972 scopus 로고    scopus 로고
    • Identification and in vivo efficacy of small-molecule antagonists of integrin alphavbeta3 (the vitronectin receptor)
    • Miller WH, Keenan RM, Willette RN, Lark MW. Identification and in vivo efficacy of small-molecule antagonists of integrin alphavbeta3 (the vitronectin receptor). Drug Discov Today 2000;5(9):397-408.
    • (2000) Drug Discov Today , vol.5 , Issue.9 , pp. 397-408
    • Miller, W.H.1    Keenan, R.M.2    Willette, R.N.3    Lark, M.W.4
  • 119
    • 0037186502 scopus 로고    scopus 로고
    • Nanomo-lar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins
    • Goodman SL, Holzemann G, Sulyok GA, Kessler H. Nanomo-lar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins. Journal of medicinal chemistry 2002;45(5):1045-51.
    • (2002) Journal of Medicinal Chemistry , vol.45 , Issue.5 , pp. 1045-1051
    • Goodman, S.L.1    Holzemann, G.2    Sulyok, G.A.3    Kessler, H.4
  • 120
    • 0033870756 scopus 로고    scopus 로고
    • Targeted antian-giogenic therapy for cancer using vitaxin: A humanized monoclonal antibody to the integrin alphavbeta3
    • Gutheil JC, Campbell TN, Pierce PR, et al. Targeted antian-giogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3. Clin Cancer Res 2000;6(8):3056-61.
    • (2000) Clin Cancer Res , vol.6 , Issue.8 , pp. 3056-3061
    • Gutheil, J.C.1    Campbell, T.N.2    Pierce, P.R.3
  • 121
    • 27744563296 scopus 로고    scopus 로고
    • Phase I trial of a monoclonal antibody specific for alphavbeta3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion
    • McNeel DG, Eickhoff J, Lee FT, et al. Phase I trial of a monoclonal antibody specific for alphavbeta3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion. Clin Cancer Res 2005;11(21): 7851-60.
    • (2005) Clin Cancer Res , vol.11 , Issue.21 , pp. 7851-7860
    • McNeel, D.G.1    Eickhoff, J.2    Lee, F.T.3
  • 122
    • 33749349945 scopus 로고    scopus 로고
    • Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent
    • Ramakrishnan V, Bhaskar V, Law DA, et al. Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent. Journal of experimental therapeutics & oncology 2006;5(4):273-86.
    • (2006) Journal of Experimental Therapeutics & Oncology , vol.5 , Issue.4 , pp. 273-286
    • Ramakrishnan, V.1    Bhaskar, V.2    Law, D.A.3
  • 123
    • 2442488748 scopus 로고    scopus 로고
    • CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo
    • Trikha M, Zhou Z, Nemeth JA, et al. CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo. International journal of cancer 2004;110(3):326-35.
    • (2004) International Journal of Cancer , vol.110 , Issue.3 , pp. 326-335
    • Trikha, M.1    Zhou, Z.2    Nemeth, J.A.3
  • 126
    • 0347155579 scopus 로고    scopus 로고
    • Phase I and pharma-cokinetic study of continuous twice weekly intravenous administration of cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours
    • Eskens FA, Dumez H, Hoekstra R, et al. Phase I and pharma-cokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours. Eur J Cancer 2003;39(7):917-26.
    • (2003) Eur J Cancer , vol.39 , Issue.7 , pp. 917-926
    • Eskens, F.A.1    Dumez, H.2    Hoekstra, R.3
  • 127
    • 0032080854 scopus 로고    scopus 로고
    • A peptidomimetic antagonist of the integrin alpha(v)beta3 inhibits leydig cell tumor growth and the development of hypercalcemia of malignancy
    • Carron CP, Meyer DM, Pegg JA, et al. A peptidomimetic antagonist of the integrin alpha(v)beta3 inhibits Leydig cell tumor growth and the development of hypercalcemia of malignancy. Cancer research 1998;58(9):1930-5.
    • (1998) Cancer Research , vol.58 , Issue.9 , pp. 1930-1935
    • Carron, C.P.1    Meyer, D.M.2    Pegg, J.A.3
  • 128
    • 0037728975 scopus 로고    scopus 로고
    • Alphavbeta3 integ-rin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice
    • Reinmuth N, Liu W, Ahmad SA, et al. Alphavbeta3 integ-rin antagonist S247 decreases colon cancer metastasis and angiogenesis and improves survival in mice. Cancer research 2003;63(9):2079-87.
    • (2003) Cancer Research , vol.63 , Issue.9 , pp. 2079-2087
    • Reinmuth, N.1    Liu, W.2    Ahmad, S.A.3
  • 131
    • 12144287687 scopus 로고    scopus 로고
    • 18F-labeled RGD peptide: Initial evaluation for imaging brain tumor angiogenesis
    • Chen X, Park R, Shahinian AH, et al. 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nuclear medicine and biology 2004;31(2):179-89.
    • (2004) Nuclear Medicine and Biology , vol.31 , Issue.2 , pp. 179-189
    • Chen, X.1    Park, R.2    Shahinian, A.H.3
  • 132
    • 0842263619 scopus 로고    scopus 로고
    • MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F-and 64Cu-labeled RGD peptide
    • Chen X, Park R, Tohme M, Shahinian AH, Bading JR, Conti PS. MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F-and 64Cu-labeled RGD peptide. Bioconjugate chemistry 2004;15(1):41-9.
    • (2004) Bioconjugate Chemistry , vol.15 , Issue.1 , pp. 41-49
    • Chen, X.1    Park, R.2    Tohme, M.3    Shahinian, A.H.4    Bading, J.R.5    Conti, P.S.6
  • 133
    • 0842263586 scopus 로고    scopus 로고
    • [18F]Galacto-RGD: Synthesis, radiolabeling, metabolic stability, and radiation dose estimates
    • Haubner R, Kuhnast B, Mang C, et al. [18F]Galacto-RGD: synthesis, radiolabeling, metabolic stability, and radiation dose estimates. Bioconjugate chemistry 2004;15(1):61-9.
    • (2004) Bioconjugate Chemistry , vol.15 , Issue.1 , pp. 61-69
    • Haubner, R.1    Kuhnast, B.2    Mang, C.3
  • 134
    • 0035266374 scopus 로고    scopus 로고
    • Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography
    • Haubner R, Wester HJ, Weber WA, et al. Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer research 2001;61(5):1781-5.
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1781-1785
    • Haubner, R.1    Wester, H.J.2    Weber, W.A.3
  • 135
    • 33750377517 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of 64Cu-labeled Abegrin TM, a humanized monoclonal antibody against integrin {alpha}v{beta}3
    • Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X. In vitro and In vivo Characterization of 64Cu-Labeled Abegrin TM, a Humanized Monoclonal Antibody against Integrin {alpha}v{beta}3. Cancer research 2006;66(19):9673-81.
    • (2006) Cancer Research , vol.66 , Issue.19 , pp. 9673-9681
    • Cai, W.1    Wu, Y.2    Chen, K.3    Cao, Q.4    Tice, D.A.5    Chen, X.6
  • 136
    • 0036930886 scopus 로고    scopus 로고
    • Comparison of a monomeric and dimeric radiolabeled RGD-peptide for tumor targeting
    • Janssen M, Oyen WJ, Massuger LF, et al. Comparison of a monomeric and dimeric radiolabeled RGD-peptide for tumor targeting. Cancer biotherapy & radiopharmaceuticals 2002;17(6):641-6.
    • (2002) Cancer Biotherapy & Radiopharmaceuticals , vol.17 , Issue.6 , pp. 641-646
    • Janssen, M.1    Oyen, W.J.2    Massuger, L.F.3
  • 137
    • 0036829759 scopus 로고    scopus 로고
    • Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model
    • Janssen ML, Oyen WJ, Dijkgraaf I, et al. Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model. Cancer research 2002;62(21):6146-51.
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6146-6151
    • Janssen, M.L.1    Oyen, W.J.2    Dijkgraaf, I.3
  • 138
    • 7444235966 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts
    • Chen X, Conti PS, Moats RA. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer research 2004;64(21):8009-14.
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 8009-8014
    • Chen, X.1    Conti, P.S.2    Moats, R.A.3
  • 139
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998;279(5349):377-80.
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 140
    • 0141990623 scopus 로고    scopus 로고
    • Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin
    • Schiffelers RM, Koning GA, ten Hagen TL, et al. Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin. J Control Release 2003;91(1-2):115-22.
    • (2003) J Control Release , vol.91 , Issue.1-2 , pp. 115-122
    • Schiffelers, R.M.1    Koning, G.A.2    Ten Hagen, T.L.3
  • 141
    • 0032835001 scopus 로고    scopus 로고
    • Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector
    • Kasono K, Blackwell JL, Douglas JT, et al. Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector. Clin Cancer Res 1999;5(9):2571-9.
    • (1999) Clin Cancer Res , vol.5 , Issue.9 , pp. 2571-2579
    • Kasono, K.1    Blackwell, J.L.2    Douglas, J.T.3
  • 142
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J, et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic acids research 2004;32(19): e149.
    • (2004) Nucleic Acids Research , vol.32 , Issue.19
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3


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