TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in Tobacco smoke-exposed lung cells

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Lemjabbar Alaoui, Hassan ^a   Sidhu, Sukhvinder S ^a   Mengistab, Aklilu ^a   Gallup, Marianne ^a   Basbaum, Carol ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE C EPSILON; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; ADAM PROTEIN; ISOENZYME; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SMOKE; SMOKING; TOBACCO; ANIMAL; BIOLOGICAL MODEL; BRONCHUS; CELL CULTURE; CHEMISTRY; ENZYMOLOGY; EPITHELIUM CELL; GENE SILENCING; LUNG; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRECANCER;

ANIMALIA; NICOTIANA TABACUM;

ADAM PROTEINS; ANIMALS; BRONCHI; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; HUMANS; ISOENZYMES; LUNG; MICE; MODELS, BIOLOGICAL; PHOSPHORYLATION; PRECANCEROUS CONDITIONS; PROTEIN KINASE C-EPSILON; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMOKING; SRC-FAMILY KINASES; TOBACCO;

EID: 79952654912     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017489     Document Type: Article

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