Hydrogen peroxide activates focal adhesion kinase and c-Src by a phosphatidylinositol 3 kinase-dependent mechanism and promotes cell migration in Caco-2 cell monolayers

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 299, Issue 1, 2010, Pages

  Basuroy, Shyamali ^a   Dunagan, Mitzi ^a   Sheth, Parimal ^a   Seth, Ankur ^a   Rao, R K ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Barrier function; Cell motility; Epithelium; Protein phosphorylation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; FOCAL ADHESION KINASE; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; WORTMANNIN; XANTHINE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL STIMULATION; CELL STRAIN CACO 2; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; INTESTINE EPITHELIUM; NONHUMAN; ONCOGENE SRC; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CACO-2 CELLS; CELL MOVEMENT; CHICKENS; CRK-ASSOCIATED SUBSTRATE PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FOCAL ADHESION KINASE 1; HUMANS; HYDROGEN PEROXIDE; INTESTINAL MUCOSA; MICE; MUTATION; OXIDANTS; OXIDATIVE STRESS; PAXILLIN; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TYROSINE; VINCULIN; XANTHINE; XANTHINE OXIDASE;

EID: 77954365525     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00368.2009     Document Type: Article

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