Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke

Toxicology and Applied Pharmacology

Volumn 141, Issue 1, 1996, Pages 76-83

  Gebremichael, A ^a   Tullis, K ^a   Denison, M S ^a   Cheek, J M ^a   Pinkerton, K E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; AROMATIC HYDROCARBON RECEPTOR; CIGARETTE SMOKE; CYTOCHROME P450 ISOENZYME; ETHOXYRESORUFIN DEETHYLASE; LUCIFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME INDUCTION; GENE EXPRESSION; GENE TRANSFER; LIVER CELL; LUNG; MOUSE; NONHUMAN;

ANIMALIA;

EID: 0030296896     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.0262     Document Type: Article

References (53)

1. Abramson, R. K., and Hutton, J. J. (1975). Effects of cigarette smoking on aryl hydrocarbon hydroxylase activity in lungs and tissues of inbred mice. Cancer Res. 35, 23-9.
2. Aix, L., Rey-Grobellet, X., Larri, G., Lesca, P., and Galtier, P. (1994). Thiabendazole is an inducer of cytochrome P4501A1 in cultured rabbit hepatocytes. Biochem. Biophys. Res. Commun. 202, 1483-1489.
3. Akin, F. J., Chamberlain, W. J., and Chortyk, O. T. (1975). Mouse skin tumorigenesis and induction of aryl hydrocarbon hydroxylase by tobacco smoke fractions. J. Natl. Cancer Inst. 54, 907-912.
4. Bartsch, H., Castegnaro, M., Rojas, M., Camus, A. M., Alexandrov, K., and Lang, M. (1992). Expression of pulmonary cytochrome P4501A1 and carcinogen DNA adduct formation in high risk subjects for tobacco-related lung cancer. Toxicol. Lett. Spec No:477-83.
5. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-54.
6. Burke, M. D., Thompson, S., Elcombe, C., Halpert, J., Haaparanta, T., and Mayer, R. (1985). Ethoxy, pentoxy and benzyloxy phenoxazones and homologues: A series of substrates to distinguish between different induced cytochrome P450. Biochem. Pharmacol. 34, 3337-3345.
7. Denison, M. S., Fisher, J. M., and Whitlock, J. P. (1988a). Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc. Natl. Acad. Sci. USA 85, 2528-2532.
8. Denison, M. S., Fisher, J. M., and Whitlock, J. P., Jr. (1988b). The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. J. Biol. Chem. 263, 17221-17224.
9. de Wet, J. R., Wood, K. V., Helinski, D. R., and DeLuca, M. (1985). Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc. Natl. Acad. Sci. USA 82, 725-737.
10. de Wet, J. R., Wood, K. V., DeLuca, M., Helinski, D. R., and Subramani, S. (1987). Firefly luciferase gene: Structure and expression in mammalian cells. Mol. Cell. Biol. 7, 725-737.
11. EPA (Environmental Protection Agency) (1992). Respiratory health effects of passive smoking: Lung cancer and other disorders, pp. 6-1-6-29. EPA, Washington, DC.
12. Garrison, P. M., Tullis, K., Aarts, J. M. M. J. G., Brouwer, A., Giesy, J. P., and Denison, M. S. (1996). Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam. Appl. Toxicol. 30, 194-203.
13. Gasiewicz, T. A., and Rucci, G. (1991). Alpha-naphthoflavone acts as an antagonist of 2,3,7,8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor. Mol. Pharmacol. 40, 607-612.
14. Gebremichael, A., Chang, A., Buckpitt, A. R., Plopper, C. G., and Pinkerton, K. E. (1995). Postnatal development of cytochrome P4501A1 and 2B1 in rat lung and liver: Effect of aged and diluted sidestream cigarette smoke. Toxicol. Appl. Pharmacol. 135, 246-253.
15. Gooden, P. M., Kass, G., Mayer, R. T., and Burke, M. D. (1987). The effects of cigarette smoke compared to 3-methylcholanthrene and phenobarbitone on alkoxyresorufin metabolism by lung and liver microsomes from rats. Biochem. Pharmacol. 6, 3393-3398.
16. Gonzalez, F. A. (1995). Genetic polymorphism and cancer susceptibility: Fourteenth Sapporo cancer seminar. Cancer Res. 55, 710-715.
17. Graziano, M. J., and Dorough, H. W. (1984). Effect of cigarette smoking on hepatic biotransformations in rats. Toxicol. Appl. Pharmacol. 75, 229-239.
18. Guengerich, F. P. (1982). Microsomal enzymes involved in toxicology-analysis and separation. In Principles and Methods in Toxicology (A. W. Hayes, Ed.), Raven Press, New York.
19. Hahn, M. E., Lamb, T. M., Schultz, M. E., Smolowitz, R. M., and Stegeman, J. (1993). Cytochrome P4501A induction and inhibition by 3,3′4,4′-tetrachlorobiphenyl in an Ah receptor-containing fish hepatoma cell line (PLHC-1). Aquat. Toxicol. 26, 185-208.
20. Hankinson, O. (1995). The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35, 307-340.
21. Hardin, J. A., Hinoshita, F., and Sherr, D. H. (1992). Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis. Toxicol. Appl. Pharmacol. 117, 155-164.
22. Kapitulnik, J., and Gonzalez, F. J. (1993). Marked endogenous activation of the CYP1A1 and CYP1A2 genes in the congenitally jaundiced Gunn rat. Mol. Pharmacol. 43, 722-725.
23. Kawajiri, K., Nakachi, K., Imai, K., Yoshii, A., Shinoda, N., and Watanabe, J. (1990). Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P4501A1 gene. FEBS 263, 131-133.
24. Kennedy, S. W., Lorenzen, A., James, C. A., and Collins, B. T. (1993). Ethoxyresorufin-O-deethylase and porphyrn analysis in chicken embryo hepatocyte cultures with a fluorescence multiwell plate reader. Anal. Biochem. 211, 102-112.
25. Lowry, O. H., Rosebrough, N. J., Farr, A. I., and Randall, R. J. (1951). Protein measurement with the folin-phenol reagent. J. Biol. Chem. 193, 265-275.
26. Lubet, R. A., Brunda, M. J., Taramelli, D., Dansie, D., Nebert, D. W., and Kouri, R. E. (1984). Induction of immunotoxicity by polycyclic hydrocarbons: Role of the Ah locus. (1984). Arch. Toxicol. 56, 18-24.
27. McLemore, T. L., Adelberg, S., Liu, M. C., McMahon, N. A., Yu, S. J., Hubbard, W. C., Czerwinski, M., Wood, T. G., Storeng, R., Lubet, R. A., et al. (1990). Expression of CYP1A1 gene in patients with lung cancer: Evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. J. Natl. Cancer Inst. 82, 1333-1339.
28. Miller, A. G., Israel, D., and Whitlock, J. P., Jr. (1983). Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity. J. Biol. Chem. 258, 523-527.
29. Nakachi, K., Imai, K., Hayashi, S., Watanabe, J., and Kawajiri, K. (1991). Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res. 51, 5177-5180.
30. Nebert, D. W., and Gelboin, H. V. (1969). The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states. Arch. Biochem. Biophys. 134, 157-168.
31. NRC (National Research Council) (1986). Environmental tobacco smoke: Measuring exposures and assessing health effects. Board on Environmental Studies and Toxicology, Committee on Passive Smoking, National Research Council, Natl. Acad. Press, Washington, DC.
32. Okamoto, T., Mitsuhashi, M., Fujita, I., Sindhu, R. K., and Kikkawa, Y. (1993). Induction of cytochrome P4501A1 and 1A2 by hyperoxia. Biochem. Biophys. Res. Commun. 197, 878-885.
33. Okey, A. B., Vella, L. M., and Harper, P. A. (1989). Detection and characterization of a low affinity form of cytosolic Ah-receptor in livers of mice nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene. Mol. Pharmacol. 35, 823-830.
34. Plopper, C. G., Weir, A. J., Morin, D., Chang, A., Philpot, R. M., and Buckpitt, A. R. (1993). Postnatal changes in the expression and distribution of pulmonary cytochrome P450 monooxygenases during Clara cell differentiation in rabbits. Mol. Pharmacol. 44, 51-61.
35. Poland, A., and Glover, E. (1976). Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol: Evidence that binding species is receptor for induction of aryl hydrocarbon hydroxylase. J. Biol. Chem. 251, 4936-4946.
36. Poland, A., and Knutson, J. C. (1982). 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22, 517-555.
37. Rajini, P., Last, J. A., Pinkerton, K. E., Hendrickx, A. G., and Witschi, H. (1994). Decreased fetal weights in rats exposed to sidestream cigarette smoke. Fundam. Appl. Toxicol. 22, 400-404.
38. Safe, S. H. (1986). Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. Annu. Rev. Pharmacol. Toxicol. 26, 371-399.
39. Sawyer, T. W., Vatcher, A. D., and Safe S. (1984). Comparative aryl hydrocarbon hydroxylase induction activity of commercial PCBs in Wistar rats and rat hepatome H-4-II E cells in culture. Chemosphere 13, 695-701.
40. Silkworth, J. B., Antrim, L., and Kaminsky, L. S. (1984). Correlations between polychlorinated biphenyl immunotoxicity, the aromatic hydrocarbon locus, and liver microsomal enzyme induction in C57BL/6 and DBA/2 mice. Toxicol. Appl. Pharmacol. 75, 156-165.
41. Swanson, H. I., and Bradfield, C. A. (1993). The Ah-receptor: Genetics, structure and function. Pharmacogenetics 3, 213-230.
42. Tachi, N., and Aoyama, M. (1983). Effect of cigarette smoke and carbon monoxide inhalation by gravid rats on the conceptus weight. Bull. Env. Contam. Toxicol. 31, 85-92.
43. Tachi, N., and Aoyama, M. (1990). Postnatal growth in rats prenatally exposed to cigarette smoke or carbon monoxide. Bull. Env. Contam. Toxicol. 45, 641-648.
44. Taioli, E., Crofts, F., Trachman, J., Demopoulos, R., Toniolo, P., and Garte, S., J. (1995). A specific African-American CYP1A1 polymorphism is associated with adenocarcinoma of the lung. Cancer Res. 55, 472-473.
45. Teague, S. V., Pinkerton, K. E., Goldsmith, M., Gebremichael, A., Chang, S., Genkins, R. A., and Moneyhun, J. H. (1994). Sidestream cigarette smoke generation and exposure system for environmental tobacco smoke studies. Inhalation Toxicol. 6, 79-93.
46. Thomas, P. E., Kouri, R. E., and Hutton, J. J. (1972). The genetics of aryl hydrocarbon hydroxylase induction in mice: A single gene difference between C57BL/6J and DBA/2J. Biochem. Genet. 6, 157-168.
47. Thompson, J. F., Hayes, L. S., and Lloyd, D. B. (1991). Modulation of firefly luciferase stability and impact on studies of gene regulation. Gene 103, 171-177.
48. Ueng, T. H., Ueng, Y. F., Chen, T. L., Park, S. S, Iwasaki, M., and Guengerich F. P. (1993). Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting. Toxicol. Appl. Pharmacol. 119, 66-73.
49. Uotila, P. (1977). Effects of single and repeated cigarette smoke-exposures on the activities of aryl hydrocarbon hydroxylase, epoxide hydratase and UDP glucuronosyltransferase in rat lung, kidney and small intestinal mucosa. Res. Commun. Chem. Pathol. Pharmacol. 17, 101-114.
50. Van Cantfort, J., and Gielen, J. (1977). Induction by cigarette smoke of aryl hydrocarbon hydroxylase activity in the rat kidney and lung. Int. J. Cancer 19, 538-545.
51. Villard, P. H., Seree, E., Lacarelle, B., Therene-Fenoglio, M. C., Barra, Y., Attolini, L., Bruguerole, B., Durand, A., and Catalin, J. (1994). Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: Evidence for CYP2E1 induction in lung. Biochem. Biophys. Res. Commun. 202, 1731-1737.
52. Whitlock, J. P., Jr. (1986). The regulation of cytochrome P-450 gene expression. Annu. Rev. Pharmacol. Toxicol. 26, 333-369.
53. Whitlock, J. P., Jr. (1993). Mechanistic aspects of dioxin action. Chem. Res. Toxicol. 6, 754-763.