Comparison of the secondary metabolites in Penicillium chrysogenum between pilot and industrial penicillin G fermentations

Applied Microbiology and Biotechnology

Volumn 89, Issue 4, 2011, Pages 1193-1202

  Cao, Ying Xiu ^a   Qiao, Bin ^a   Lu, Hua ^b   Chen, Yao ^b   Yuan, Ying Jin ^a  

^a TIANJIN UNIVERSITY   (China)

^b CSPC Pharmaceutical Technology Co Ltd   (China)

Author keywords

Penicillin fermentation; Penicillium chrysogenum; Q TOF MS; Scale up; Secondary metabolites

Indexed keywords

PENICILLIN FERMENTATION; PENICILLIUM CHRYSOGENUM; Q-TOF-MS; SCALE-UP; SECONDARY METABOLITES;

AMINO ACIDS; BIOMOLECULES; CARBOXYLIC ACIDS; DRUG PRODUCTS; ENZYME ACTIVITY; FERMENTATION; INDUCTIVELY COUPLED PLASMA; INDUSTRY; LAKES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM;

METABOLITES;

6 AMINOPENICILLANIC ACID; 6 OXOPIPERIDE 2 CARBOXYLIC ACID; AMINO ACID DERIVATIVE; BIS DELTA(ALPHA AMINOADIPYL)CYSTEINYL VALINE; CARBOXYLIC ACID DERIVATIVE; ISOPENICILLIN N; ISOPENICILLIN N SYNTHETASE; PENICILLIN G; PENICILLIN G DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTICS; BIOMASS; CARBOXYLIC ACID; COMPARATIVE STUDY; CONCENTRATION (COMPOSITION); CULTIVATION; ENZYME ACTIVITY; FERMENTATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SCALE EFFECT; SECONDARY METABOLITE;

ARTICLE; BACTERIAL METABOLISM; BIOMASS PRODUCTION; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FERMENTATION; FERMENTATION TECHNIQUE; INDUSTRIAL FERMENTATION; INDUSTRIAL PRODUCTION; LARGE SCALE PRODUCTION; METABOLITE; NONHUMAN; PENICILLIUM CHRYSOGENUM; PILOT FERMENTATION; PRODUCTIVITY; QUADRUPOLE MASS SPECTROMETRY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SECONDARY METABOLITE;

CHROMATOGRAPHY, LIQUID; FERMENTATION; OLIGOPEPTIDES; PENICILLIN G; PENICILLINS; PENICILLIUM CHRYSOGENUM; TANDEM MASS SPECTROMETRY;

PENICILLIUM CHRYSOGENUM;

EID: 79952535527     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2910-y     Document Type: Article

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