Early dysregulation of the mitochondrial proteome in a mouse model of Alzheimer's disease

Journal of Proteomics

Volumn 74, Issue 4, 2011, Pages 466-479

  Chou, Jose L ^a   Shenoy, Deepa V ^a   Thomas, Nicy ^a   Choudhary, Pankaj K ^a   LaFerla, Frank M ^b   Goodman, Steven R ^a,c   Breen, Gail A M ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

2D DIGE; Alzheimer's disease; BN SDS PAGE; Comparative proteomics; IEF SDS PAGE; Mitochondrial proteomics; Triple transgenic AD mice

Indexed keywords

KETONE; MITOCHONDRIAL PROTEIN; PROTEOME; TAU PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN DYSFUNCTION; CITRIC ACID CYCLE; CONTROLLED STUDY; FATTY ACID OXIDATION; GENE MUTATION; GLYCOLYSIS; HUMAN; ION TRANSPORT; MALE; METABOLISM; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; TRANSGENE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ALZHEIMER DISEASE; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; NEUROFIBRILLARY TANGLES; PROTEOME; PROTEOMICS; TIME FACTORS; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

MUS; MUS MUSCULUS;

EID: 79952247298     PISSN: 18743919     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprot.2010.12.012     Document Type: Article

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