메뉴 건너뛰기




Volumn 118, Issue 1, 2009, Pages 181-195

The role of proteomics in dementia and Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA ENOLASE; ALPHA1 GLYCOPROTEIN; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; BETA 2 MICROGLOBULIN; BETA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C4A; CYSTATIN C; FATTY ACID BINDING PROTEIN; FIBRINOGEN; FRUCTOSE BISPHOSPHATE ALDOLASE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN HEAVY CHAIN; PENTRAXIN; PEROXIREDOXIN 2; PHOSPHOGLYCERATE MUTASE; PROSTAGLANDIN D SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RETINOL BINDING PROTEIN; THIOREDOXIN; TRIOSEPHOSPHATE ISOMERASE; VOLTAGE DEPENDENT ANION CHANNEL;

EID: 67349280701     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-009-0502-7     Document Type: Review
Times cited : (54)

References (112)
  • 1
    • 33747409456 scopus 로고    scopus 로고
    • Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders
    • Abdi F, Quinn JF, Jankovic J et al (2006) Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis 9:293-348
    • (2006) J Alzheimers Dis , vol.9 , pp. 293-348
    • Abdi, F.1    Quinn, J.F.2    Jankovic, J.3
  • 2
    • 0019177562 scopus 로고
    • Increased activity of brain and platelet monoamine-oxidase in dementia of Alzheimer type
    • doi: 10.1016/0024-3205(80)90025-9
    • Adolfsson R, Gottfries CG, Oreland L, Wiberg A, Winblad B (1980) Increased activity of brain and platelet monoamine-oxidase in dementia of Alzheimer type. Life Sci 27:1029-1034. doi: 10.1016/ 0024-3205(80)90025-9
    • (1980) Life Sci , vol.27 , pp. 1029-1034
    • Adolfsson, R.1    Gottfries, C.G.2    Oreland, L.3    Wiberg, A.4    Winblad, B.5
  • 4
    • 0035917819 scopus 로고    scopus 로고
    • Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease
    • doi: 10.1016/S0304-3940(01)01636-6
    • Aksenov MY, Markesbery WR (2001) Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease. Neurosci Lett 302:141-145. doi: 10.1016/ S0304-3940(01)01636-6
    • (2001) Neurosci Lett , vol.302 , pp. 141-145
    • Aksenov, M.Y.1    Markesbery, W.R.2
  • 5
    • 0022462178 scopus 로고
    • Isoelectric-focusing and two-dimensional gel-electrophoresis in plasma and cerebrospinal-fluid from patients with dementia
    • doi: 10.1159/000116023
    • Alafuzoff I, Adolfsson R, Bucht G, Jellum E, Mehta PD, Winblad B (1986) Isoelectric-focusing and two-dimensional gel-electrophoresis in plasma and cerebrospinal-fluid from patients with dementia. Eur Neurol 25:285-289. doi: 10.1159/000116023
    • (1986) Eur Neurol , vol.25 , pp. 285-289
    • Alafuzoff, I.1    Adolfsson, R.2    Bucht, G.3    Jellum, E.4    Mehta, P.D.5    Winblad, B.6
  • 6
    • 0037253267 scopus 로고    scopus 로고
    • A novel experimental design for comparative two-dimensional gel analysis: Two-dimensional difference gel electrophoresis incorporating a pooled internal standard
    • doi: 10.1002/pmic.200390006
    • Alban A, David SO, Bjorkesten L et al (2003) A novel experimental design for comparative two-dimensional gel analysis: Two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics 3:36-44. doi: 10.1002/pmic.200390006
    • (2003) Proteomics , vol.3 , pp. 36-44
    • Alban, A.1    David, S.O.2    Bjorkesten, L.3
  • 7
    • 0026743110 scopus 로고
    • Distribution of Alzheimer-type pathological changes in nondemented elderly individuals matches the pattern in Alzheimers disease
    • Arriagada PV, Marzloff K, Hyman BT (1992) Distribution of Alzheimer-type pathological changes in nondemented elderly individuals matches the pattern in Alzheimers disease. Neurology 42:1681-1688
    • (1992) Neurology , vol.42 , pp. 1681-1688
    • Arriagada, P.V.1    Marzloff, K.2    Hyman, B.T.3
  • 8
    • 25144513449 scopus 로고    scopus 로고
    • CSF biomarkers for Alzheimer's disease: Use in early diagnosis and evaluation of drug treatment
    • doi: 10.1586/14737159.5.5.661
    • Blennow K (2005) CSF biomarkers for Alzheimer's disease: Use in early diagnosis and evaluation of drug treatment. Expert Rev Mol Diagn 5:661-672. doi: 10.1586/14737159.5.5.661
    • (2005) Expert Rev Mol Diagn , vol.5 , pp. 661-672
    • Blennow, K.1
  • 9
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • doi: 10.1016/S1474-4422(03)00530-1
    • Blennow K, Hampel H (2003) CSF markers for incipient Alzheimer's disease. Lancet Neurol 2:605-613. doi: 10.1016/S1474-4422(03)00530-1
    • (2003) Lancet Neurol , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 10
    • 55749111850 scopus 로고    scopus 로고
    • Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease
    • doi: 10.1002/pmic.200800375
    • Brechlin P, Jahn O, Steinacker P et al (2008) Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease. Proteomics 8:4357-4366. doi: 10.1002/pmic.200800375
    • (2008) Proteomics , vol.8 , pp. 4357-4366
    • Brechlin, P.1    Jahn, O.2    Steinacker, P.3
  • 11
    • 1842467230 scopus 로고    scopus 로고
    • Proteomic analysis of oxidatively modified proteins in Alzheimer's disease brain: Insights into neurodegeneration
    • Butterfield DA, Castegna A (2003) Proteomic analysis of oxidatively modified proteins in Alzheimer's disease brain: Insights into neurodegeneration. Cell Mol Biol 49:747-751
    • (2003) Cell Mol Biol , vol.49 , pp. 747-751
    • Butterfield, D.A.1    Castegna, A.2
  • 12
    • 34548588380 scopus 로고    scopus 로고
    • Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder
    • Butterfield DA, Sultana R (2007) Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: Insights into the progression of this dementing disorder. J Alzheimers Dis 12:61-72
    • (2007) J Alzheimers Dis , vol.12 , pp. 61-72
    • Butterfield, D.A.1    Sultana, R.2
  • 13
    • 44849106187 scopus 로고    scopus 로고
    • Identification of 3-nitrotyosine-modified brain proteins by redox proteomics. Nitric oxide, Part F
    • Butterfield DA, Sultana R (2008) Identification of 3-nitrotyosine-modified brain proteins by redox proteomics. Nitric oxide, Part F. Methods Enzymol 440:295-308
    • (2008) Methods Enzymol , vol.440 , pp. 295-308
    • Butterfield, D.A.1    Sultana, R.2
  • 14
    • 0141767139 scopus 로고    scopus 로고
    • Proteomics in Alzheimer's disease: Insights into potential mechanisms of neurodegeneration
    • doi: 10.1046/j.1471-4159.2003.01948.x
    • Butterfield DA, Boyd-Kimball D, Castegna A (2003) Proteomics in Alzheimer's disease: Insights into potential mechanisms of neurodegeneration. J Neurochem 86:1313-1327. doi: 10.1046/ j.1471-4159.2003.01948.x
    • (2003) J Neurochem , vol.86 , pp. 1313-1327
    • Butterfield, D.A.1    Boyd-Kimball, D.2    Castegna, A.3
  • 15
    • 33747036919 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics
    • doi: 10.1016/j.ejphar.2006.06.026
    • Butterfield DA, Perluigi M, Sultana R (2006) Oxidative stress in Alzheimer's disease brain: New insights from redox proteomics. Eur J Pharmacol 545:39-50. doi: 10.1016/j.ejphar.2006.06.026
    • (2006) Eur J Pharmacol , vol.545 , pp. 39-50
    • Butterfield, D.A.1    Perluigi, M.2    Sultana, R.3
  • 16
    • 0041358773 scopus 로고    scopus 로고
    • A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease
    • doi: 10.1002/pmic.200300470
    • Carrette O, Demalte I, Scherl A et al (2003) A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease. Proteomics 3:1486-1494. doi: 10.1002/pmic.200300470
    • (2003) Proteomics , vol.3 , pp. 1486-1494
    • Carrette, O.1    Demalte, I.2    Scherl, A.3
  • 17
    • 33645776682 scopus 로고    scopus 로고
    • Comparative proteomics of cerebrospinal fluid in neuropathologically confirmed Alzheimer's disease and non-demented elderly subjects
    • doi: 10.1179/016164106X98035
    • Castano EM, Roher AE, Esh CL, Kokjohn TA, Beach T (2006) Comparative proteomics of cerebrospinal fluid in neuropathologically confirmed Alzheimer's disease and non-demented elderly subjects. Neurol Res 28:155-163. doi: 10.1179/016164106X98035
    • (2006) Neurol Res , vol.28 , pp. 155-163
    • Castano, E.M.1    Roher, A.E.2    Esh, C.L.3    Kokjohn, T.A.4    Beach, T.5
  • 18
    • 0037101889 scopus 로고    scopus 로고
    • Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part 1. Creatine kinase bb, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
    • doi: 10.1016/S0891-5849(02)00914-0
    • Castegna A, Aksenov M, Aksenova M et al (2002) Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part 1. Creatine kinase bb, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med 33:562-571. doi: 10.1016/ S0891-5849(02)00914-0
    • (2002) Free Radic Biol Med , vol.33 , pp. 562-571
    • Castegna, A.1    Aksenov, M.2    Aksenova, M.3
  • 19
    • 0036733145 scopus 로고    scopus 로고
    • Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II. Dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71
    • doi: 10.1046/j.1471-4159.2002.01103.x
    • Castegna A, Aksenov M, Thongboonkerd V et al (2002) Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II. Dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. J Neurochem 82:1524-1532. doi: 10.1046/ j.1471-4159.2002.01103.x
    • (2002) J Neurochem , vol.82 , pp. 1524-1532
    • Castegna, A.1    Aksenov, M.2    Thongboonkerd, V.3
  • 20
    • 0038472495 scopus 로고    scopus 로고
    • Proteomic identification of nitrated proteins in Alzheimer's disease brain
    • doi: 10.1046/j.1471-4159.2003.01786.x
    • Castegna A, Thongboonkerd V, Klein JB, Lynn B, Markesbery WR, Butterfield DA (2003) Proteomic identification of nitrated proteins in Alzheimer's disease brain. J Neurochem 85:1394-1401. doi: 10.1046/ j.1471-4159.2003.01786.x
    • (2003) J Neurochem , vol.85 , pp. 1394-1401
    • Castegna, A.1    Thongboonkerd, V.2    Klein, J.B.3    Lynn, B.4    Markesbery, W.R.5    Butterfield, D.A.6
  • 21
    • 0026706930 scopus 로고
    • Weighing naked proteins: Practical, high-accuracy mass measurement of peptides and proteins
    • doi: 10.1126/science.1411504
    • Chait BT, Kent SBH (1992) Weighing naked proteins: Practical, high-accuracy mass measurement of peptides and proteins. Science 257:1885-1894. doi: 10.1126/science.1411504
    • (1992) Science , vol.257 , pp. 1885-1894
    • Chait, B.T.1    Kent, S.B.H.2
  • 22
    • 1542405141 scopus 로고    scopus 로고
    • Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease
    • Cheon MS, Kim SH, Fountoulakis M, Lubec G (2003) Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease. J Neural Trans Suppl 225-234
    • (2003) J Neural Trans Suppl , pp. 225-234
    • Cheon, M.S.1    Kim, S.H.2    Fountoulakis, M.3    Lubec, G.4
  • 23
    • 0036638618 scopus 로고    scopus 로고
    • Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease
    • doi: 10.1002/1522-2683(200207)23:14<2247::AID-ELPS2247>3.0.CO;2-M
    • Choe LH, Dutt MJ, Relkin N, Lee KH (2002) Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease. Electrophoresis 23:2247-2251. doi: 10.1002/ 1522-2683(200207)23:14<2247::AID-ELPS2247>3.0.CO;2-M
    • (2002) Electrophoresis , vol.23 , pp. 2247-2251
    • Choe, L.H.1    Dutt, M.J.2    Relkin, N.3    Lee, K.H.4
  • 24
    • 11144290985 scopus 로고    scopus 로고
    • Proteomic analysis of human serum by two-dimensional differential gel electrophoresis after depletion of high-abundant proteins
    • doi: 10.1021/pr049921p
    • Chromy BA, Gonzales AD, Perkins J et al (2004) Proteomic analysis of human serum by two-dimensional differential gel electrophoresis after depletion of high-abundant proteins. J Proteome Res 3:1120-1127. doi: 10.1021/pr049921p
    • (2004) J Proteome Res , vol.3 , pp. 1120-1127
    • Chromy, B.A.1    Gonzales, A.D.2    Perkins, J.3
  • 25
    • 1042265051 scopus 로고    scopus 로고
    • Platelet APP, ADAM 10 and BACE alterations in the early stages of Alzheimer disease
    • Colciaghi F, Marcello E, Borroni B et al (2004) Platelet APP, ADAM 10 and BACE alterations in the early stages of Alzheimer disease. Neurology 62:498-501
    • (2004) Neurology , vol.62 , pp. 498-501
    • Colciaghi, F.1    Marcello, E.2    Borroni, B.3
  • 26
    • 0037203346 scopus 로고    scopus 로고
    • Studies of the pathophysiological mechanisms in frontotemporal dementia by proteome analysis of CSF proteins
    • doi: 10.1016/S0169-328X(02)00549-1
    • Davidsson P, Sjogren M, Andreasen N et al (2002) Studies of the pathophysiological mechanisms in frontotemporal dementia by proteome analysis of CSF proteins. Brain Res Mol Brain Res 109:128-133. doi: 10.1016/S0169-328X(02)00549-1
    • (2002) Brain Res Mol Brain Res , vol.109 , pp. 128-133
    • Davidsson, P.1    Sjogren, M.2    Andreasen, N.3
  • 27
    • 0037117721 scopus 로고    scopus 로고
    • Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients
    • doi: 10.1097/00001756-200204160-00015
    • Davidsson P, Westman-Brinkmalm A, Nilsson CL et al (2002) Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients. Neuroreport 13:611-615. doi: 10.1097/00001756-200204160-00015
    • (2002) Neuroreport , vol.13 , pp. 611-615
    • Davidsson, P.1    Westman-Brinkmalm, A.2    Nilsson, C.L.3
  • 28
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimers disease: Revising the NINCDS-ADRDA criteria
    • doi: 10.1016/S1474-4422(07)70178-3
    • Dubois B, Feldman HH, Jacova C et al (2007) Research criteria for the diagnosis of Alzheimers disease: Revising the NINCDS-ADRDA criteria. Lancet Neurol 6:734-746. doi: 10.1016/S1474-4422(07)70178-3
    • (2007) Lancet Neurol , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3
  • 29
    • 0032915003 scopus 로고    scopus 로고
    • A comparative proteome analysis of hippocampal tissue from schizophrenic and Alzheimer's disease individuals
    • doi: 10.1038/sj.mp.4000463
    • Edgar PF, Schonberger SJ, Dean B, Faull RLM, Kydd R, Cooper GJS (1999) A comparative proteome analysis of hippocampal tissue from schizophrenic and Alzheimer's disease individuals. Mol Psychiatry 4:173-178. doi: 10.1038/sj.mp.4000463
    • (1999) Mol Psychiatry , vol.4 , pp. 173-178
    • Edgar, P.F.1    Schonberger, S.J.2    Dean, B.3    Faull, R.L.M.4    Kydd, R.5    Cooper, G.J.S.6
  • 30
    • 0024438708 scopus 로고
    • Electrospray ionization for mass-spectrometry of large biomolecules
    • doi: 10.1126/science.2675315
    • Fenn JB, Mann M, Meng CK, Wong SF, Whitehouse CM (1989) Electrospray ionization for mass-spectrometry of large biomolecules. Science 246:64-71. doi: 10.1126/science.2675315
    • (1989) Science , vol.246 , pp. 64-71
    • Fenn, J.B.1    Mann, M.2    Meng, C.K.3    Wong, S.F.4    Whitehouse, C.M.5
  • 31
    • 33847665648 scopus 로고    scopus 로고
    • Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease
    • doi: 10.1002/ana.21038
    • Finehout EJ, Franck Z, Choe LH, Relkin N, Lee KH (2007) Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease. Ann Neurol 61:120-129. doi: 10.1002/ana.21038
    • (2007) Ann Neurol , vol.61 , pp. 120-129
    • Finehout, E.J.1    Franck, Z.2    Choe, L.H.3    Relkin, N.4    Lee, K.H.5
  • 32
    • 0032585827 scopus 로고    scopus 로고
    • Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome
    • Fountoulakis M, Cairns N, Lubec G (1999) Increased levels of 14-3-3 gamma and epsilon proteins in brain of patients with Alzheimer's disease and Down syndrome. J Neural Transm Suppl 57:323-335
    • (1999) J Neural Transm Suppl , vol.57 , pp. 323-335
    • Fountoulakis, M.1    Cairns, N.2    Lubec, G.3
  • 33
    • 29244432517 scopus 로고    scopus 로고
    • Problems associated with biological markers of Alzheimer's disease
    • doi: 10.1007/s11064-005-8827-7
    • Frey HJ, Mattila KM, Korolainen MA, Pirttila T (2005) Problems associated with biological markers of Alzheimer's disease. Neurochem Res 30:1501-1510. doi: 10.1007/s11064-005-8827-7
    • (2005) Neurochem Res , vol.30 , pp. 1501-1510
    • Frey, H.J.1    Mattila, K.M.2    Korolainen, M.A.3    Pirttila, T.4
  • 34
    • 32244435907 scopus 로고    scopus 로고
    • Role of genes and environments for explaining Alzheimer disease
    • doi: 10.1001/archpsyc.63.2.168
    • Gatz M, Reynolds CA, Fratiglioni L et al (2006) Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry 63:168-174. doi: 10.1001/archpsyc.63.2.168
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 168-174
    • Gatz, M.1    Reynolds, C.A.2    Fratiglioni, L.3
  • 35
    • 0025634268 scopus 로고
    • Neurochemical aspects on aging and diseases with cognitive impairment
    • doi: 10.1002/jnr.490270415
    • Gottfries CG (1990) Neurochemical aspects on aging and diseases with cognitive impairment. J Neurosci Res 27:541-547. doi: 10.1002/ jnr.490270415
    • (1990) J Neurosci Res , vol.27 , pp. 541-547
    • Gottfries, C.G.1
  • 36
    • 0032947530 scopus 로고    scopus 로고
    • Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease
    • doi: 10.1002/(SICI)1522-2683(19990101)20:4/ 5<928::AID-ELPS928>3.0.CO;2-Z
    • Greber S, Lubec G, Cairns N, Fountoulakis M (1999) Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease. Electrophoresis 20:928-934. doi: 10.1002/(SICI)1522-2683(19990101)20:4/5<928::AID-ELPS928>3.0.CO;2-Z
    • (1999) Electrophoresis , vol.20 , pp. 928-934
    • Greber, S.1    Lubec, G.2    Cairns, N.3    Fountoulakis, M.4
  • 37
    • 77049308856 scopus 로고
    • Aging: A theory based on free-radical and radiation chemistry
    • Harman D (1956) Aging: A theory based on free-radical and radiation chemistry. J Gerontol 11:298-300
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 38
    • 0142213542 scopus 로고    scopus 로고
    • The free radical theory of aging
    • doi: 10.1089/152308603770310202
    • Harman D (2003) The free radical theory of aging. Antioxid Redox Signal 5:557-561. doi: 10.1089/152308603770310202
    • (2003) Antioxid Redox Signal , vol.5 , pp. 557-561
    • Harman, D.1
  • 39
    • 0022606619 scopus 로고
    • Abnormal proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    • Harrington MG, Merril CR, Asher DM, Gajdusek DC (1986) Abnormal proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. N Engl J Med 315:279-383
    • (1986) N Engl J Med , vol.315 , pp. 279-383
    • Harrington, M.G.1    Merril, C.R.2    Asher, D.M.3    Gajdusek, D.C.4
  • 40
    • 0032434055 scopus 로고    scopus 로고
    • How and why we age
    • doi: 10.1016/S0531-5565(98)00023-0
    • Hayflick L (1998) How and why we age. Exp Gerontol 33:639-653. doi: 10.1016/S0531-5565(98)00023-0
    • (1998) Exp Gerontol , vol.33 , pp. 639-653
    • Hayflick, L.1
  • 41
    • 0028807137 scopus 로고
    • Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation
    • Hensley K, Hall N, Subramaniam R et al (1995) Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J Neurochem 65:2146-2156
    • (1995) J Neurochem , vol.65 , pp. 2146-2156
    • Hensley, K.1    Hall, N.2    Subramaniam, R.3
  • 42
    • 33745442821 scopus 로고    scopus 로고
    • The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome
    • doi: 10.1373/clinchem.2006.069252
    • Hortin GL (2006) The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome. Clin Chem 52:1223-1237. doi: 10.1373/ clinchem.2006.069252
    • (2006) Clin Chem , vol.52 , pp. 1223-1237
    • Hortin, G.L.1
  • 43
    • 33745479870 scopus 로고    scopus 로고
    • Proteomics: A new diagnostic frontier
    • doi: 10.1373/clinchem.2006.067280
    • Hortin GL, Jortani SA, Ritchie JC, Valdes R, Chan DW (2006) Proteomics: a new diagnostic frontier. Clin Chem 52:1218-1222. doi: 10.1373/ clinchem.2006.067280
    • (2006) Clin Chem , vol.52 , pp. 1218-1222
    • Hortin, G.L.1    Jortani, S.A.2    Ritchie, J.C.3    Valdes, R.4    Chan, D.W.5
  • 44
    • 0029840653 scopus 로고    scopus 로고
    • The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies
    • doi: 10.1056/NEJM199609263351303
    • Hsich G, Kinney K, Gibbs CJ, Lee KH, Harrington MG (1996) The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies. N Engl J Med 335:924-930. doi: 10.1056/ NEJM199609263351303
    • (1996) N Engl J Med , vol.335 , pp. 924-930
    • Hsich, G.1    Kinney, K.2    Gibbs, C.J.3    Lee, K.H.4    Harrington, M.G.5
  • 45
    • 29244434070 scopus 로고    scopus 로고
    • Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid
    • doi: 10.1074/mcp.M500207-MCP200
    • Hu Y, Malone JP, Fagan AM, Townsend RR, Holtzman DM (2005) Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid. Mol Cell Proteomics 4:2000-2009. doi: 10.1074/ mcp.M500207-MCP200
    • (2005) Mol Cell Proteomics , vol.4 , pp. 2000-2009
    • Hu, Y.1    Malone, J.P.2    Fagan, A.M.3    Townsend, R.R.4    Holtzman, D.M.5
  • 46
    • 33750596715 scopus 로고    scopus 로고
    • Proteome-based plasma biomarkers for Alzheimer's disease
    • doi: 10.1093/brain/awl279
    • Hye A, Lynham S, Thambisetty M et al (2006) Proteome-based plasma biomarkers for Alzheimer's disease. Brain 129:3042-3050. doi: 10.1093/ brain/awl279
    • (2006) Brain , vol.129 , pp. 3042-3050
    • Hye, A.1    Lynham, S.2    Thambisetty, M.3
  • 47
    • 34247875825 scopus 로고    scopus 로고
    • Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm?
    • doi: 10.1016/j.jns.2007.01.025
    • Imhof A, Kovari E, von Gunten A et al (2007) Morphological substrates of cognitive decline in nonagenarians and centenarians: A new paradigm? J Neurol Sci 257:72-79. doi: 10.1016/j.jns.2007.01.025
    • (2007) J Neurol Sci , vol.257 , pp. 72-79
    • Imhof, A.1    Kovari, E.2    von Gunten, A.3
  • 48
    • 0034772403 scopus 로고    scopus 로고
    • The role of separation science in proteomics research
    • doi: 10.1002/1522-2683(200109)22:17<3629::AID-ELPS3629>3.0.CO;2-O
    • Issaq HJ (2001) The role of separation science in proteomics research. Electrophoresis 22:3629-3638. doi: 10.1002/ 1522-2683(200109)22:17<3629::AID-ELPS3629>3.0.CO;2-O
    • (2001) Electrophoresis , vol.22 , pp. 3629-3638
    • Issaq, H.J.1
  • 49
    • 0030842576 scopus 로고    scopus 로고
    • Neuropathological staging of Alzheimer-related lesions: The challenge of establishing relations to age
    • doi: 10.1016/S0197-4580(97)00048-1
    • Jellinger KA (1997) Neuropathological staging of Alzheimer-related lesions: The challenge of establishing relations to age. Neurobiol Aging 18:369-375. doi: 10.1016/S0197-4580(97)00048-1
    • (1997) Neurobiol Aging , vol.18 , pp. 369-375
    • Jellinger, K.A.1
  • 50
    • 59349092999 scopus 로고    scopus 로고
    • Criteria for the neuropathological diagnosis of dementing disorders: Routes out of the swamp?
    • doi: 10.1007/s00401-008-0466-z
    • Jellinger KA (2009) Criteria for the neuropathological diagnosis of dementing disorders: Routes out of the swamp? Acta Neuropathol 117:101-110. doi: 10.1007/s00401-008-0466-z
    • (2009) Acta Neuropathol , vol.117 , pp. 101-110
    • Jellinger, K.A.1
  • 51
    • 33746296891 scopus 로고    scopus 로고
    • Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: Relevance to Parkinson disease
    • doi: 10.1074/mcp.M500382-MCP200
    • Jin JH, Hulette C, Wang Y et al (2006) Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: Relevance to Parkinson disease. Mol Cell Proteomics 5:1193-1204. doi: 10.1074/mcp.M500382-MCP200
    • (2006) Mol Cell Proteomics , vol.5 , pp. 1193-1204
    • Jin, J.H.1    Hulette, C.2    Wang, Y.3
  • 52
    • 42049083159 scopus 로고    scopus 로고
    • Both plasma retinol-binding protein and haptoglobin precursor allele 1 in CSF: Candidate biomarkers for the progression of normal to mild cognitive impairment to Alzheimer's disease
    • doi: 10.1016/j.neulet.2008.03.010
    • Jung SM, Lee K, Lee J et al (2008) Both plasma retinol-binding protein and haptoglobin precursor allele 1 in CSF: Candidate biomarkers for the progression of normal to mild cognitive impairment to Alzheimer's disease. Neurosci Lett 436:153-157. doi: 10.1016/j.neulet.2008.03.010
    • (2008) Neurosci Lett , vol.436 , pp. 153-157
    • Jung, S.M.1    Lee, K.2    Lee, J.3
  • 53
    • 16844382331 scopus 로고    scopus 로고
    • Evidence of increased oxidative damage in subjects with mild cognitive impairment
    • Keller JN, Schmitt FA, Scheff SW et al (2005) Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 64:1152-1156
    • (2005) Neurology , vol.64 , pp. 1152-1156
    • Keller, J.N.1    Schmitt, F.A.2    Scheff, S.W.3
  • 54
    • 0033679409 scopus 로고    scopus 로고
    • Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome
    • doi: 10.1007/PL00000661
    • Kim SH, Vlkolinsky R, Cairns N, Lubec G (2000) Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome. Cell Mol Life Sci 57:1810-1816. doi: 10.1007/PL00000661
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1810-1816
    • Kim, S.H.1    Vlkolinsky, R.2    Cairns, N.3    Lubec, G.4
  • 55
    • 0035805113 scopus 로고    scopus 로고
    • The reduction of NADH ubiquinone oxidoreductase 24-and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease
    • doi: 10.1016/S0024-3205(01)01074-8
    • Kim SH, Vlkolinsky R, Cairns N, Fountoulakis M, Lubec G (2001) The reduction of NADH ubiquinone oxidoreductase 24-and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease. Life Sci 68:2741-2750. doi: 10.1016/S0024-3205(01)01074-8
    • (2001) Life Sci , vol.68 , pp. 2741-2750
    • Kim, S.H.1    Vlkolinsky, R.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 56
    • 34147221048 scopus 로고    scopus 로고
    • Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease
    • doi: 10.1373/clinchem.2006.078014
    • Korolainen MA, Nyman TA, Nyyssonen P, Hartikainen ES, Pirttila T (2007) Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease. Clin Chem 53:657-665. doi: 10.1373/clinchem.2006.078014
    • (2007) Clin Chem , vol.53 , pp. 657-665
    • Korolainen, M.A.1    Nyman, T.A.2    Nyyssonen, P.3    Hartikainen, E.S.4    Pirttila, T.5
  • 57
    • 0344406145 scopus 로고    scopus 로고
    • Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders
    • doi: 10.1016/S0006-8993(02)04243-9
    • Krapfenbauer K, Engidawork E, Cairns N, Fountoulakis M, Lubec G (2003) Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain Res 967:152-160. doi: 10.1016/S0006-8993(02)04243-9
    • (2003) Brain Res , vol.967 , pp. 152-160
    • Krapfenbauer, K.1    Engidawork, E.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 58
    • 38349016262 scopus 로고    scopus 로고
    • Molecular mechanisms and potential clinical significance of S-glutathionylation
    • doi: 10.1089/ars.2007.1716
    • le-Donne I, Milzani A, Gagliano N, Colombo R, Giustarini D, Rossi R (2008) Molecular mechanisms and potential clinical significance of S-glutathionylation. Antioxid Redox Signal 10:445-473. doi: 10.1089/ ars.2007.1716
    • (2008) Antioxid Redox Signal , vol.10 , pp. 445-473
    • le-Donne, I.1    Milzani, A.2    Gagliano, N.3    Colombo, R.4    Giustarini, D.5    Rossi, R.6
  • 59
    • 33947537591 scopus 로고    scopus 로고
    • Proteomic identification of novel proteins in cortical Lewy bodies
    • doi: 10.1111/j.1750-3639.2007.00048.x
    • Leverenz JB, Umar I, Wang Q et al (2007) Proteomic identification of novel proteins in cortical Lewy bodies. Brain Pathol 17:139-145. doi: 10.1111/j.1750-3639.2007.00048.x
    • (2007) Brain Pathol , vol.17 , pp. 139-145
    • Leverenz, J.B.1    Umar, I.2    Wang, Q.3
  • 60
    • 4344570364 scopus 로고    scopus 로고
    • Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection
    • doi: 10.1074/jbc.M403672200
    • Lia LJ, Cheng DM, Wang J et al (2004) Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. J Biol Chem 279:37061-37068. doi: 10.1074/jbc.M403672200
    • (2004) J Biol Chem , vol.279 , pp. 37061-37068
    • Lia, L.J.1    Cheng, D.M.2    Wang, J.3
  • 61
    • 43049124437 scopus 로고    scopus 로고
    • Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: A reference data set
    • doi: 10.1152/physiolgenomics.00242.2007
    • Liang WS, Dunckley T, Beach TG et al (2008) Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: A reference data set. Physiol Genomics 33:240-256. doi: 10.1152/ physiolgenomics.00242.2007
    • (2008) Physiol Genomics , vol.33 , pp. 240-256
    • Liang, W.S.1    Dunckley, T.2    Beach, T.G.3
  • 62
    • 0038025565 scopus 로고    scopus 로고
    • Proteomics in brain research: Potentials and limitations
    • doi: 10.1016/S0301-0082(03)00036-4
    • Lubec G, Krapfenbauer K, Fountoulakis M (2003) Proteomics in brain research: Potentials and limitations. Prog Neurobiol 69:193-211. doi: 10.1016/S0301-0082(03)00036-4
    • (2003) Prog Neurobiol , vol.69 , pp. 193-211
    • Lubec, G.1    Krapfenbauer, K.2    Fountoulakis, M.3
  • 63
    • 0028287485 scopus 로고
    • Alzheimer brain proteins investigated by 2-dimensional gel-electrophoresis with immobilized pH gradients in the first dimension
    • doi: 10.1002/elps.1150150199
    • Mattila KM, Frey H (1994) Alzheimer brain proteins investigated by 2-dimensional gel-electrophoresis with immobilized pH gradients in the first dimension. Electrophoresis 15:721-725. doi: 10.1002/elps.1150150199
    • (1994) Electrophoresis , vol.15 , pp. 721-725
    • Mattila, K.M.1    Frey, H.2
  • 64
    • 0029175962 scopus 로고
    • Two-dimensional analysis of qualitative and quantitative changes in blood-cell proteins in Alzheimer's disease: Search for extraneuronal markers
    • Mattila KM, Frey H (1995) Two-dimensional analysis of qualitative and quantitative changes in blood-cell proteins in Alzheimer's disease: search for extraneuronal markers. Appl Theor Electrophor 4:189-196
    • (1995) Appl Theor Electrophor , vol.4 , pp. 189-196
    • Mattila, K.M.1    Frey, H.2
  • 65
    • 57049151865 scopus 로고    scopus 로고
    • Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions
    • doi: 10.1074/mcp.M800116-MCP200
    • McFarland MA, Ellis CE, Markey SP, Nussbaum RL (2008) Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Mol Cell Proteomics 7:2123-2137. doi: 10.1074/ mcp.M800116-MCP200
    • (2008) Mol Cell Proteomics , vol.7 , pp. 2123-2137
    • McFarland, M.A.1    Ellis, C.E.2    Markey, S.P.3    Nussbaum, R.L.4
  • 66
    • 0035246248 scopus 로고    scopus 로고
    • Mass analysis at the advent of the 21st century
    • doi: 10.1021/cr990087a
    • McLuckey SA, Wells JM (2001) Mass analysis at the advent of the 21st century. Chem Rev 101:571-606. doi: 10.1021/cr990087a
    • (2001) Chem Rev , vol.101 , pp. 571-606
    • McLuckey, S.A.1    Wells, J.M.2
  • 67
    • 0032839281 scopus 로고    scopus 로고
    • Mitochondrial genome lesions in the pathogenesis of sporadic Alzheimer's disease
    • doi: 10.1159/000022104
    • Meier-Ruge WA, Bertoni-Freddari C (1999) Mitochondrial genome lesions in the pathogenesis of sporadic Alzheimer's disease. Gerontology 45:289-297. doi: 10.1159/000022104
    • (1999) Gerontology , vol.45 , pp. 289-297
    • Meier-Ruge, W.A.1    Bertoni-Freddari, C.2
  • 68
    • 51449086260 scopus 로고    scopus 로고
    • Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium
    • doi: 10.1016/j.neurobiolaging.2007.04.004
    • Mhyre TR, Loy R, Tariot PN et al (2008) Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium. Neurobiol Aging 29:1631-1643. doi: 10.1016/ j.neurobiolaging.2007.04.004
    • (2008) Neurobiol Aging , vol.29 , pp. 1631-1643
    • Mhyre, T.R.1    Loy, R.2    Tariot, P.N.3
  • 69
    • 0142151385 scopus 로고    scopus 로고
    • Overcoming technical variation and biological variation in quantitative proteomics
    • doi: 10.1002/pmic.200300534
    • Molloy MP, Brzezinski EE, Hang JQ, McDowell MT, VanBogelen RA (2003) Overcoming technical variation and biological variation in quantitative proteomics. Proteomics 3:1912-1919. doi: 10.1002/pmic.200300534
    • (2003) Proteomics , vol.3 , pp. 1912-1919
    • Molloy, M.P.1    Brzezinski, E.E.2    Hang, J.Q.3    McDowell, M.T.4    VanBogelen, R.A.5
  • 70
    • 58049221284 scopus 로고    scopus 로고
    • Disease state, age, sex, and post-mortem time-dependent expression of proteins in AD vs. control frontal cortex brain samples
    • doi: 10.2174/156720508786898488
    • Müller T, Jung K, Ullrich A et al (2008) Disease state, age, sex, and post-mortem time-dependent expression of proteins in AD vs. control frontal cortex brain samples. Curr Alzheimer Res 5:562-571. doi: 10.2174/ 156720508786898488
    • (2008) Curr Alzheimer Res , vol.5 , pp. 562-571
    • Müller, T.1    Jung, K.2    Ullrich, A.3
  • 71
    • 0025179173 scopus 로고
    • Expression of monoamine oxidase-B activity in astrocytes of senile plaques
    • doi: 10.1007/BF00307697
    • Nakamura S, Kawamata T, Akiguchi I, Kameyama M, Nakamura N, Kimura H (1990) Expression of monoamine oxidase-B activity in astrocytes of senile plaques. Acta Neuropathol 80:419-425. doi: 10.1007/BF00307697
    • (1990) Acta Neuropathol , vol.80 , pp. 419-425
    • Nakamura, S.1    Kawamata, T.2    Akiguchi, I.3    Kameyama, M.4    Nakamura, N.5    Kimura, H.6
  • 72
    • 34248223082 scopus 로고    scopus 로고
    • An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach
    • doi: 10.1002/jnr.21275
    • Newman SF, Sultana R, Perluigi M et al (2007) An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach. J Neurosci Res 85:1506-1514. doi: 10.1002/ jnr.21275
    • (2007) J Neurosci Res , vol.85 , pp. 1506-1514
    • Newman, S.F.1    Sultana, R.2    Perluigi, M.3
  • 73
    • 0016711037 scopus 로고
    • High-resolution 2-dimensional electrophoresis of proteins
    • Ofarrell PH (1975) High-resolution 2-dimensional electrophoresis of proteins. J Biol Chem 250:4007-4021
    • (1975) J Biol Chem , vol.250 , pp. 4007-4021
    • Ofarrell, P.H.1
  • 74
    • 33750600611 scopus 로고    scopus 로고
    • Proteome informatics I: Bioinformatics tools for processing experimental data
    • doi: 10.1002/pmic.200600273
    • Palagi PM, Hernandez P, Walther D, Appel RD (2006) Proteome informatics I: Bioinformatics tools for processing experimental data. Proteomics 6:5435-5444. doi: 10.1002/pmic.200600273
    • (2006) Proteomics , vol.6 , pp. 5435-5444
    • Palagi, P.M.1    Hernandez, P.2    Walther, D.3    Appel, R.D.4
  • 75
    • 33750441499 scopus 로고    scopus 로고
    • An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid
    • doi: 10.1016/j.neulet.2006.09.044
    • Portelius E, Zetterberg H, Andreasson U et al (2006) An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid. Neurosci Lett 409:215-219. doi: 10.1016/j.neulet.2006.09.044
    • (2006) Neurosci Lett , vol.409 , pp. 215-219
    • Portelius, E.1    Zetterberg, H.2    Andreasson, U.3
  • 76
    • 52049096219 scopus 로고    scopus 로고
    • Characterization of tau in cerebrospinal fluid using mass spectrometry
    • doi: 10.1021/pr7008669
    • Portelius E, Hansson SF, Tran AJ et al (2008) Characterization of tau in cerebrospinal fluid using mass spectrometry. J Proteome Res 7:2114-2120. doi: 10.1021/pr7008669
    • (2008) J Proteome Res , vol.7 , pp. 2114-2120
    • Portelius, E.1    Hansson, S.F.2    Tran, A.J.3
  • 77
    • 0036284936 scopus 로고    scopus 로고
    • Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease
    • doi: 10.1001/archneur.59.6.972
    • Pratico D, Clark CM, Liun F, Lee VYM, Trojanowski JQ (2002) Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease. Arch Neurol 59:972-976. doi: 10.1001/ archneur.59.6.972
    • (2002) Arch Neurol , vol.59 , pp. 972-976
    • Pratico, D.1    Clark, C.M.2    Liun, F.3    Lee, V.Y.M.4    Trojanowski, J.Q.5
  • 78
    • 0141957321 scopus 로고    scopus 로고
    • Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease
    • doi: 10.1016/j.molbrainres.2003.08.005
    • Puchades M, Hansson SF, Nilsson CL, Andreasen N, Blennow K, Davidsson P (2003) Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease. Brain Res Mol Brain Res 118:140-146. doi: 10.1016/j.molbrainres.2003.08.005
    • (2003) Brain Res Mol Brain Res , vol.118 , pp. 140-146
    • Puchades, M.1    Hansson, S.F.2    Nilsson, C.L.3    Andreasen, N.4    Blennow, K.5    Davidsson, P.6
  • 79
    • 35948933394 scopus 로고    scopus 로고
    • Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    • doi: 10.1038/nm1653
    • Ray S, Britschgi M, Herbert C et al (2007) Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 13:1359-1362. doi: 10.1038/nm1653
    • (2007) Nat Med , vol.13 , pp. 1359-1362
    • Ray, S.1    Britschgi, M.2    Herbert, C.3
  • 80
    • 67349210585 scopus 로고    scopus 로고
    • Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule
    • [Epub ahead of print]
    • Reed T, Pierce WM, Turner DM, Markesbery WR, Butterfield DA (2008) Proteomic identification of nitrated brain proteins in early Alzheimer's disease inferior parietal lobule. J Cell Mol Med [Epub ahead of print]
    • (2008) J Cell Mol Med
    • Reed, T.1    Pierce, W.M.2    Turner, D.M.3    Markesbery, W.R.4    Butterfield, D.A.5
  • 81
    • 19944432197 scopus 로고    scopus 로고
    • Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
    • doi: 10.1074/mcp.M400129-MCP200
    • Ross PL, Huang YLN, Marchese JN et al (2004) Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 3:1154-1169. doi: 10.1074/ mcp.M400129-MCP200
    • (2004) Mol Cell Proteomics , vol.3 , pp. 1154-1169
    • Ross, P.L.1    Huang, Y.L.N.2    Marchese, J.N.3
  • 82
    • 27744487547 scopus 로고    scopus 로고
    • Identification of CSF biomarkers for frontotemporal dementia using SELDI-TOF
    • doi: 10.1016/j.expneurol.2005.08.002
    • Ruetschi U, Zetterberg H, Podust VN et al (2005) Identification of CSF biomarkers for frontotemporal dementia using SELDI-TOF. Exp Neurol 196:273-281. doi: 10.1016/j.expneurol.2005.08.002
    • (2005) Exp Neurol , vol.196 , pp. 273-281
    • Ruetschi, U.1    Zetterberg, H.2    Podust, V.N.3
  • 83
    • 0028869597 scopus 로고
    • Human diseases with defects in oxidative phosphorylation. 2. F1F0 Atp-synthase defects in Alzheimer disease revealed by blue native polyacrylamide-gel electrophoresis
    • doi: 10.1111/j.1432-1033.1995.tb20219.x
    • Schagger H, Ohm TG (1995) Human diseases with defects in oxidative phosphorylation. 2. F1F0 Atp-synthase defects in Alzheimer disease revealed by blue native polyacrylamide-gel electrophoresis. Eur J Biochem 227:916-921. doi: 10.1111/j.1432-1033.1995.tb20219.x
    • (1995) Eur J Biochem , vol.227 , pp. 916-921
    • Schagger, H.1    Ohm, T.G.2
  • 84
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels
    • doi: 10.1021/ac950914h
    • Shevchenko A, Wilm M, Vorm O, Mann M (1996) Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels. Anal Chem 68:850-858. doi: 10.1021/ac950914h
    • (1996) Anal Chem , vol.68 , pp. 850-858
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 85
    • 3042573766 scopus 로고    scopus 로고
    • Proteome analysis of brain proteins in Alzheimer's disease: Subproteomics following sequentially extracted protein preparation
    • Shiozaki A, Tsuji T, Kohno R et al (2004) Proteome analysis of brain proteins in Alzheimer's disease: Subproteomics following sequentially extracted protein preparation. J Alzheimers Dis 6:257-268
    • (2004) J Alzheimers Dis , vol.6 , pp. 257-268
    • Shiozaki, A.1    Tsuji, T.2    Kohno, R.3
  • 86
    • 33947287762 scopus 로고    scopus 로고
    • Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
    • doi: 10.1001/archneur.64.3.366
    • Simonsen AH, McGuire J, Hansson O et al (2007) Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment. Arch Neurol 64:366-370. doi: 10.1001/archneur.64.3.366
    • (2007) Arch Neurol , vol.64 , pp. 366-370
    • Simonsen, A.H.1    McGuire, J.2    Hansson, O.3
  • 87
    • 43849111501 scopus 로고    scopus 로고
    • Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease
    • doi: 10.1016/j.neurobiolaging.2007.01.011
    • Simonsen AH, McGuire J, Podust VN et al (2008) Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease. Neurobiol Aging 29:961-968. doi: 10.1016/j.neurobiolaging.2007.01.011
    • (2008) Neurobiol Aging , vol.29 , pp. 961-968
    • Simonsen, A.H.1    McGuire, J.2    Podust, V.N.3
  • 88
    • 6944233454 scopus 로고    scopus 로고
    • Ion activation methods for tandem mass spectrometry
    • doi: 10.1002/jms.703
    • Sleno L, Volmer DA (2004) Ion activation methods for tandem mass spectrometry. J Mass Spectrom 39:1091-1112. doi: 10.1002/jms.703
    • (2004) J Mass Spectrom , vol.39 , pp. 1091-1112
    • Sleno, L.1    Volmer, D.A.2
  • 89
    • 0025790342 scopus 로고
    • Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
    • doi: 10.1073/pnas.88.23.10540
    • Smith CD, Carney JM, Starkereed PE et al (1991) Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 88:10540-10543. doi: 10.1073/ pnas.88.23.10540
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10540-10543
    • Smith, C.D.1    Carney, J.M.2    Starkereed, P.E.3
  • 90
    • 53149130215 scopus 로고    scopus 로고
    • Neuronal gene expression correlates of Parkinson's disease with dementia
    • doi: 10.1002/mds.22184
    • Stamper C, Siegel A, Liang WS et al (2008) Neuronal gene expression correlates of Parkinson's disease with dementia. Mov Disord 23:1588-1595. doi: 10.1002/mds.22184
    • (2008) Mov Disord , vol.23 , pp. 1588-1595
    • Stamper, C.1    Siegel, A.2    Liang, W.S.3
  • 91
    • 33748423353 scopus 로고    scopus 로고
    • Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD
    • doi: 10.1016/j.neurobiolaging.2005.09.021
    • Sultana R, Boyd-Kimball D, Poon HF et al (2006) Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD. Neurobiol Aging 27:1564-1576. doi: 10.1016/ j.neurobiolaging.2005.09.021
    • (2006) Neurobiol Aging , vol.27 , pp. 1564-1576
    • Sultana, R.1    Boyd-Kimball, D.2    Poon, H.F.3
  • 92
    • 33645089917 scopus 로고    scopus 로고
    • Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach
    • doi: 10.1016/j.nbd.2005.10.004
    • Sultana R, Poon HF, Cai J et al (2006) Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiol Dis 22:76-87. doi: 10.1016/j.nbd.2005.10.004
    • (2006) Neurobiol Dis , vol.22 , pp. 76-87
    • Sultana, R.1    Poon, H.F.2    Cai, J.3
  • 93
    • 34347332414 scopus 로고    scopus 로고
    • Proteomics analysis of the Alzheimer's disease hippocampal proteome
    • Sultana R, Boyd-Kimball D, Cai J et al (2007) Proteomics analysis of the Alzheimer's disease hippocampal proteome. J Alzheimers Dis 11:153-164
    • (2007) J Alzheimers Dis , vol.11 , pp. 153-164
    • Sultana, R.1    Boyd-Kimball, D.2    Cai, J.3
  • 94
    • 34548172399 scopus 로고    scopus 로고
    • Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: A regional study
    • doi: 10.1111/j.1582-4934.2007.00065.x
    • Sultana R, Reed T, Perluigi M, Coccia R, Pierce WM, Butterfield DA (2007) Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: A regional study. J Cell Mol Med 11:839-851. doi: 10.1111/j.1582-4934.2007.00065.x
    • (2007) J Cell Mol Med , vol.11 , pp. 839-851
    • Sultana, R.1    Reed, T.2    Perluigi, M.3    Coccia, R.4    Pierce, W.M.5    Butterfield, D.A.6
  • 95
    • 33744957510 scopus 로고    scopus 로고
    • Quantitation in two-dimensional fluorescence difference gel electrophoresis: Effect of protein fixation
    • doi: 10.1002/elps.200500710
    • Tannu N, Hemby SE (2006) Quantitation in two-dimensional fluorescence difference gel electrophoresis: Effect of protein fixation. Electrophoresis 27:2011-2015. doi: 10.1002/elps.200500710
    • (2006) Electrophoresis , vol.27 , pp. 2011-2015
    • Tannu, N.1    Hemby, S.E.2
  • 96
    • 13844281502 scopus 로고    scopus 로고
    • Peptide mass fingerprinting
    • doi: 10.1016/j.ymeth.2004.08.015
    • Thiede B, Hohenwarter W, Krah A et al (2005) Peptide mass fingerprinting. Methods 35:237-247. doi: 10.1016/j.ymeth.2004.08.015
    • (2005) Methods , vol.35 , pp. 237-247
    • Thiede, B.1    Hohenwarter, W.2    Krah, A.3
  • 97
    • 0036807924 scopus 로고    scopus 로고
    • Proteomic profiling and neurodegeneration in Alzheimer's disease
    • doi: 10.1023/A:1020941929414
    • Tsuji T, Shiozaki A, Kohno R, Yoshizato K, Shimohama S (2002) Proteomic profiling and neurodegeneration in Alzheimer's disease. Neurochem Res 27:1245-1253. doi: 10.1023/A:1020941929414
    • (2002) Neurochem Res , vol.27 , pp. 1245-1253
    • Tsuji, T.1    Shiozaki, A.2    Kohno, R.3    Yoshizato, K.4    Shimohama, S.5
  • 98
    • 0034120636 scopus 로고    scopus 로고
    • Analysis of blood plasma proteins in patients with Alzheimer's disease by two-dimensional electrophoresis, sequence homology and immunodetection
    • doi: 10.1002/ (SICI)1522-2683(20000501)21:9<1832::AID-ELPS1832>3.0.CO;2-7
    • Ueno I, Sakai T, Yamaoka M, Yoshida R, Tsugita A (2000) Analysis of blood plasma proteins in patients with Alzheimer's disease by two-dimensional electrophoresis, sequence homology and immunodetection. Electrophoresis 21:1832-1845. doi: 10.1002/ (SICI)1522-2683(20000501)21:9<1832::AID-ELPS1832>3.0.CO;2-7
    • (2000) Electrophoresis , vol.21 , pp. 1832-1845
    • Ueno, I.1    Sakai, T.2    Yamaoka, M.3    Yoshida, R.4    Tsugita, A.5
  • 99
    • 0017773790 scopus 로고
    • Polymorphism of Apolipoprotein-e and occurrence of dys-beta-lipoproteinemia in man
    • doi: 10.1038/269604a0
    • Utermann G, Hees M, Steinmetz A (1977) Polymorphism of Apolipoprotein-e and occurrence of dys-beta-lipoproteinemia in man. Nature 269:604-607. doi: 10.1038/269604a0
    • (1977) Nature , vol.269 , pp. 604-607
    • Utermann, G.1    Hees, M.2    Steinmetz, A.3
  • 100
    • 0034969003 scopus 로고    scopus 로고
    • Decreased brain levels of 2′, 3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer's disease
    • doi: 10.1016/S0197-4580(01)00218-4
    • Vlkolinsky R, Cairns N, Fountoulakis M, Lubec G (2001) Decreased brain levels of 2′, 3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer's disease. Neurobiol Aging 22:547-553. doi: 10.1016/S0197-4580(01)00218-4
    • (2001) Neurobiol Aging , vol.22 , pp. 547-553
    • Vlkolinsky, R.1    Cairns, N.2    Fountoulakis, M.3    Lubec, G.4
  • 101
    • 18144406844 scopus 로고    scopus 로고
    • Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament in tau binding protein
    • doi: 10.1096/fj.04-2370com
    • Wang Q, Woltjer RL, Cimino PJ et al (2005) Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament in tau binding protein. FASEB J 19:869-871. doi: 10.1096/fj.04-2370com
    • (2005) FASEB J , vol.19 , pp. 869-871
    • Wang, Q.1    Woltjer, R.L.2    Cimino, P.J.3
  • 102
    • 27144527588 scopus 로고    scopus 로고
    • Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling
    • doi: 10.1002/pmic.200401255
    • Wilson KE, Marouga R, Prime JE et al (2005) Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling. Proteomics 5:3851-3858. doi: 10.1002/ pmic.200401255
    • (2005) Proteomics , vol.5 , pp. 3851-3858
    • Wilson, K.E.1    Marouga, R.2    Prime, J.E.3
  • 103
    • 39049097692 scopus 로고    scopus 로고
    • Biological variation of the platelet proteome in the elderly population and its implication for biomarker research
    • doi: 10.1074/mcp.M700137-MCP200
    • Winkler W, Zellner M, Diestinger M et al (2008) Biological variation of the platelet proteome in the elderly population and its implication for biomarker research. Mol Cell Proteomics 7:193-203. doi: 10.1074/ mcp.M700137-MCP200
    • (2008) Mol Cell Proteomics , vol.7 , pp. 193-203
    • Winkler, W.1    Zellner, M.2    Diestinger, M.3
  • 104
    • 33644845960 scopus 로고    scopus 로고
    • Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D gel- or LC-MALDI TOF/TOF
    • doi: 10.1021/pr050405o
    • Wu WW, Wang GH, Baek SJ, Shen RF (2006) Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D gel- or LC-MALDI TOF/TOF. J Proteome Res 5:651-658. doi: 10.1021/pr050405o
    • (2006) J Proteome Res , vol.5 , pp. 651-658
    • Wu, W.W.1    Wang, G.H.2    Baek, S.J.3    Shen, R.F.4
  • 105
    • 34249720583 scopus 로고    scopus 로고
    • Interaction of amyloid binding alcohol dehydrogenase/A beta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model
    • doi: 10.1016/j.mcn.2007.03.013
    • Yao Y, Taylor M, Davey F et al (2007) Interaction of amyloid binding alcohol dehydrogenase/A beta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model. Mol Cell Neurosci 35:377-382. doi: 10.1016/j.mcn.2007.03.013
    • (2007) Mol Cell Neurosci , vol.35 , pp. 377-382
    • Yao, Y.1    Taylor, M.2    Davey, F.3
  • 106
    • 0035170823 scopus 로고    scopus 로고
    • Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome
    • doi: 10.1002/1522-2683(200101)22:1<172::AID-ELPS172>3.0.CO;2-P
    • Yoo BC, Fountoulakis M, Cairns N, Lubec G (2001) Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome. Electrophoresis 22:172-179. doi: 10.1002/ 1522-2683(200101)22:1<172::AID-ELPS172>3.0.CO;2-P
    • (2001) Electrophoresis , vol.22 , pp. 172-179
    • Yoo, B.C.1    Fountoulakis, M.2    Cairns, N.3    Lubec, G.4
  • 107
    • 0034805931 scopus 로고    scopus 로고
    • Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease
    • doi: 10.1006/bbrc.2000.4109
    • Yoo BC, Kim SH, Cairns N, Fountoulakis M, Lubec G (2001) Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease. Biochem Biophys Res Commun 280:249-258. doi: 10.1006/bbrc.2000.4109
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 249-258
    • Yoo, B.C.1    Kim, S.H.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 108
    • 0019433761 scopus 로고
    • Human very low-density lipoprotein apolipoprotein-e isoprotein polymorphism is explained by genetic variation and posttranslational modification
    • doi: 10.1021/bi00507a059
    • Zannis VI, Breslow JL (1981) Human very low-density lipoprotein apolipoprotein-e isoprotein polymorphism is explained by genetic variation and posttranslational modification. Biochemistry 20:1033-1041. doi: 10.1021/bi00507a059
    • (1981) Biochemistry , vol.20 , pp. 1033-1041
    • Zannis, V.I.1    Breslow, J.L.2
  • 109
    • 0942276226 scopus 로고    scopus 로고
    • Mining biomarkers in human sera using proteomic tools
    • doi: 10.1002/pmic.200300495
    • Zhang RL, Barker L, Pinchev D et al (2004) Mining biomarkers in human sera using proteomic tools. Proteomics 4:244-256. doi: 10.1002/ pmic.200300495
    • (2004) Proteomics , vol.4 , pp. 244-256
    • Zhang, R.L.1    Barker, L.2    Pinchev, D.3
  • 110
    • 20944443414 scopus 로고    scopus 로고
    • Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease
    • Zhang J, Goodlett DR, Quinn JF et al (2005) Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. J Alzheimers Dis 7:125-133
    • (2005) J Alzheimers Dis , vol.7 , pp. 125-133
    • Zhang, J.1    Goodlett, D.R.2    Quinn, J.F.3
  • 111
    • 42949119345 scopus 로고    scopus 로고
    • CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases
    • doi: 10.1309/W01Y0B808EMEH12L
    • Zhang J, Sokal I, Peskind ER et al (2008) CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases. Am J Clin Pathol 129:526-529. doi: 10.1309/W01Y0B808EMEH12L
    • (2008) Am J Clin Pathol , vol.129 , pp. 526-529
    • Zhang, J.1    Sokal, I.2    Peskind, E.R.3
  • 112
    • 33750634123 scopus 로고    scopus 로고
    • The proteomic search for diagnostic biomarkers: Lost in translation?
    • doi: 10.1074/mcp.R600001-MCP200
    • Zolg W (2006) The proteomic search for diagnostic biomarkers: Lost in translation? Mol Cell Proteomics 5:1720-1726. doi: 10.1074/ mcp.R600001-MCP200
    • (2006) Mol Cell Proteomics , vol.5 , pp. 1720-1726
    • Zolg, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.