Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance

Journal of Clinical Investigation

Volumn 121, Issue 3, 2011, Pages 918-929

  Jin, Wanzhu ^a   Goldfine, Allison B ^a   Boes, Tanner ^a   Henry, Robert R ^b   Ciaraldi, Theodore P ^b   Kim, Eun Young ^a   Emecan, Merve ^a   Fitzpatrick, Connor ^a   Sen, Anish ^a   Shah, Ankit ^a   Mun, Edward ^c   Vokes, Martha ^a   Schroeder, Joshua ^a   Tatro, Elizabeth ^a   Jimenez Chillaron, Jose ^a   Patti, Mary Elizabeth ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G ACTIN; MEGAKARYOBLASTIC LEUKEMIA 1 PROTEIN; ROSIGLITAZONE; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; FAMILY HISTORY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; MOUSE; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTINS; ANIMALS; BIOPSY; COHORT STUDIES; CYTOSKELETON; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; PHOSPHORYLATION; RATS; SERUM RESPONSE FACTOR; SIGNAL TRANSDUCTION;

EID: 79952221472     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI41940     Document Type: Article

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