Reactive oxygen species (ROS) accumulation induced by mononaphthalimide- spermidine leads to intrinsic and AIF-mediated apoptosis in HeLa cells

Oncology Reports

Volumn 25, Issue 4, 2011, Pages 1099-1107

  Yang, Lianhe ^a,b   Zhao, Jin ^a   Zhu, Yanqin ^b   Tian, Zhiyong ^a   Wang, Chaojie ^a  

^a HENAN UNIVERSITY   (China)

^b HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Mechanism; Mononaphthalimide spermidine

Indexed keywords

ACETYLCYSTEINE; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; CYTOCHROME C; GLUTATHIONE; MONONAPHTHALIMIDE; NAPHTHALIMIDE DERIVATIVE; POLYAMINE OXIDASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SPERMIDINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ENZYME ACTIVITY; ENZYME RELEASE; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; BLOTTING, WESTERN; CASPASES; CYTOCHROMES C; CYTOSOL; GLUTATHIONE; HELA CELLS; HUMANS; MITOCHONDRIA; NAPHTHALIMIDES; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; REACTIVE OXYGEN SPECIES; SPERMIDINE;

EID: 79952203218     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1173     Document Type: Article

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