The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 1, 2007, Pages 541-545

  Oliveira, João ^a   Ralton, Lynda ^a   Tavares, Joana ^c   Codeiro da Silva, Anabela ^c   Bestwick, Charles S ^b   McPherson, Anne ^a   Thoo Lin, Paul Kong ^a  

^a ROBERT GORDON UNIVERSITY   (United Kingdom)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Anticancer; Antiparasitic activity; Bisnaphthalimidopropyl; Polyamines

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALKYL GROUP; BISNAPHTHALIMIDOPROPYL POLYAMINE; BISNAPHTHALIMIDOPROPYLSPERMIDINE; NITROGEN; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN CACO 2; COLON CANCER; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LEISHMANIA INFANTUM; PARASITE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIPARASITIC AGENTS; CACO-2 CELLS; CELL PROLIFERATION; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEISHMANIA INFANTUM; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; POLYAMINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

LEISHMANIA INFANTUM;

EID: 33750942260     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.031     Document Type: Article

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