Synergistic antitumor effects of anthracenylmethyl homospermidine and alpha-difluoromethylornithine on promyelocytic leukemia HL60 cells

Toxicology in Vitro

Volumn 22, Issue 2, 2008, Pages 352-358

  Xie, Song qiang ^a,b   Liu, Guang chao ^a   Ma, Yuan fang ^a   Cheng, Peng fei ^a   Wu, Ying liang ^b   Wang, Min wei ^b   Ji, Bian sheng ^a   Zhao, Jin ^a   Wang, Chao jie ^a  

^a HENAN UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; Cell cycle; Mitochondria membrane potential; Polyamine conjugate

Indexed keywords

ANTHRACENYLMETHYLHOMOSPERMIDINE; ANTINEOPLASTIC AGENT; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; EFLORNITHINE; MATRIX METALLOPROTEINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NITROBLUE TETRAZOLIUM TEST; PROMYELOCYTIC LEUKEMIA; WESTERN BLOTTING;

ANTHRACENES; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CASPASES; CELL CYCLE; CELL PROLIFERATION; CYTOCHROMES C; DRUG SYNERGISM; EFLORNITHINE; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; SPERMIDINE;

EID: 38549141763     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.09.017     Document Type: Article

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