Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidine

Toxicology

Volumn 263, Issue 2-3, 2009, Pages 127-133

  Xie, Song Qiang ^a   Wang, Jian Hong ^a   Ma, Hong Xia ^a   Cheng, Peng Fei ^a   Zhao, Jin ^a   Wang, Chao Jie ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

Apoptosis; Polyamine conjugate; Polyamine transporter recognization; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ANTHRACENYMETHYL HOMOSPERMIDINE; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; CASPASE 3; CASPASE 9; CYCLOPHOSPHAMIDE; CYTOCHROME C; MATRIX METALLOPROTEINASE; PHOSPHATIDYLSERINE; POLYAMINE OXIDASE; POLYAMINE TRANSPORTER; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DAMAGE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG TOLERABILITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME RELEASE; LUNG METASTASIS; MELANOMA; MELANOMA CELL; MITOCHONDRIAL TOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT;

ACETYLCYSTEINE; ANIMALS; ANTHRACENES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LUNG NEOPLASMS; MATRIX METALLOPROTEINASES; MELANOMA, EXPERIMENTAL; MEMBRANE TRANSPORT PROTEINS; MICE; MITOCHONDRIA; NEOPLASM METASTASIS; OXIDATIVE STRESS; POLYAMINES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SPERMIDINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 68549085062     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.07.001     Document Type: Article

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