-
1
-
-
37749037799
-
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs
-
Zobel K, Wang L, Varfolomeev E, et al: Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. ACS Chem Biol 1: 525-533, 2006.
-
(2006)
ACS Chem Biol
, vol.1
, pp. 525-533
-
-
Zobel, K.1
Wang, L.2
Varfolomeev, E.3
-
2
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
Fesik SW: Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 5: 876-885, 2005.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 876-885
-
-
Fesik, S.W.1
-
3
-
-
17844364904
-
Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: Structure-activity relationship with linarin and linarin acetate
-
DOI 10.1093/carcin/bgi014
-
Singh RP, Agrawal P, Yim D, Agarwal C and Agarwal R: Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate. Carcinogenesis 26: 845-854, 2005. (Pubitemid 41214348)
-
(2005)
Carcinogenesis
, vol.26
, Issue.4
, pp. 845-854
-
-
Singh, R.P.1
Agrawal, P.2
Yim, D.3
Agarwal, C.4
Agarwal, R.5
-
4
-
-
0037067317
-
Mediation of poty(ADP-ribose) polymerase-1 - Dependent cell death by apoptosis-inducing factor
-
DOI 10.1126/science.1072221
-
Yu SW, Wang H, Poitras MF, et al: Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297: 259-263, 2002. (Pubitemid 34761289)
-
(2002)
Science
, vol.297
, Issue.5579
, pp. 259-263
-
-
Yu, S.-W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
5
-
-
33748606380
-
Mechanisms of fenretinide-induced apoptosis
-
DOI 10.1007/s10495-006-9289-3
-
Hail N Jr, Kim HJ and Lotan R: Mechanisms of fenretinide-induced apoptosis. Apoptosis 11: 1677-1694, 2006. (Pubitemid 44376243)
-
(2006)
Apoptosis
, vol.11
, Issue.10
, pp. 1677-1694
-
-
Hail Jr., N.1
Kim, H.J.2
Lotan, R.3
-
6
-
-
2442561553
-
Apoptosis as a novel target for cancer chemoprevention
-
Sun SY, Hail N Jr and Lotan R: Apoptosis as a novel target for cancer chemoprevention. J Natl Cancer Inst 96: 662-672, 2004.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 662-672
-
-
Sun, S.Y.1
Hail Jr., N.2
Lotan, R.3
-
7
-
-
0035992229
-
Apoptosis: Target of cancer therapy
-
Ferreira CG, Epping M, Kruyt FA and Giaccone G: Apoptosis: target of cancer therapy. Clin Cancer Res 8: 2024-2034, 2002. (Pubitemid 34753570)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2024-2034
-
-
Ferreira, C.G.1
Epping, M.2
Kruyt, F.A.E.3
Giaccone, G.4
-
8
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO: The biochemistry of apoptosis. Nature 407: 770-776, 2000.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
9
-
-
55749109699
-
The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues
-
Liu H, Dong A, Gao C, Tan C, Zu X and Jiang Y: The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues. Bioorg Med Chem 16: 10013-10021, 2008.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 10013-10021
-
-
Liu, H.1
Dong, A.2
Gao, C.3
Tan, C.4
Zu, X.5
Jiang, Y.6
-
10
-
-
51449119650
-
Synthesis and potent antileukemic activities of 10-benzyl-9(10H)- acridinones
-
Gao C, Jiang Y, Tan C, Zu X, Liu H and Cao D: Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones. Bioorg Med Chem 16: 8670-8675, 2008.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 8670-8675
-
-
Gao, C.1
Jiang, Y.2
Tan, C.3
Zu, X.4
Liu, H.5
Cao, D.6
-
11
-
-
0029835537
-
Epidemiological studies on brassica vegetables and cancer risk
-
Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H and van den Brandt PA: Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomarkers Prev 5: 733-748, 1996.
-
(1996)
Cancer Epidemiol Biomarkers Prev
, vol.5
, pp. 733-748
-
-
Verhoeven, D.T.1
Goldbohm, R.A.2
Van Poppel, G.3
Verhagen, H.4
Van Den Brandt, P.A.5
-
13
-
-
0035987188
-
Isothiocyanates as cancer chemopreventive agents: Their biological activities and metabolism in rodents and humans
-
DOI 10.2174/1389200023337496
-
Conaway CC, Yang YM and Chung FL: Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans. Curr Drug Metab 3: 233-255, 2002. (Pubitemid 34625038)
-
(2002)
Current Drug Metabolism
, vol.3
, Issue.3
, pp. 233-255
-
-
Conaway, C.C.1
Yang, Y.-M.2
Chung, F.-L.3
-
14
-
-
73649091148
-
Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate
-
Warin R, Chambers WH, Potter DM and Singh SV: Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate. Cancer Res 69: 9473-9480, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 9473-9480
-
-
Warin, R.1
Chambers, W.H.2
Potter, D.M.3
Singh, S.V.4
-
15
-
-
33845221445
-
Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
-
DOI 10.1158/1535-7163.MCT-06-0396
-
Xiao D, Vogel V and Singh SV: Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak. Mol Cancer Ther 5: 2931-2945, 2006. (Pubitemid 44849021)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.11
, pp. 2931-2945
-
-
Xiao, D.1
Vogel, V.2
Singh, S.V.3
-
16
-
-
1942451371
-
Selected isothiocyanates rapidly induce growth inhibition of cancer cells
-
Zhang Y, Tang L and Gonzalez V: Selected isothiocyanates rapidly induce growth inhibition of cancer cells. Mol Cancer Ther 2: 1045-1052, 2003.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1045-1052
-
-
Zhang, Y.1
Tang, L.2
Gonzalez, V.3
-
17
-
-
4444231754
-
Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines
-
Tseng E, Scott-Ramsay EA and Morris ME: Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines. Exp Biol Med (Maywood) 229: 835-842, 2004. (Pubitemid 39166489)
-
(2004)
Experimental Biology and Medicine
, vol.229
, Issue.8
, pp. 835-842
-
-
Tseng, E.1
Scott-Ramsay, E.A.2
Morris, M.E.3
-
18
-
-
57649174596
-
Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells
-
Xiao D, Powolny AA and Singh SV: Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells. J Biol Chem 283: 30151-30163, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 30151-30163
-
-
Xiao, D.1
Powolny, A.A.2
Singh, S.V.3
-
19
-
-
10344230716
-
Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: Implication for prevention against inflammation-related carcinogenesis
-
DOI 10.1093/carcin/bgh051
-
Miyoshi N, Takabayashi S, Osawa T and Nakamura Y: Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis. Carcinogenesis 25: 567-575, 2004. (Pubitemid 38499945)
-
(2004)
Carcinogenesis
, vol.25
, Issue.4
, pp. 567-575
-
-
Miyoshi, N.1
Takabayashi, S.2
Osawa, T.3
Nakamura, Y.4
-
20
-
-
37849032113
-
Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25-35)-induced toxicity in cultured rat cortical neurons
-
Ban JY, Nguyen HT, Lee HJ, et al: Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25-35)-induced toxicity in cultured rat cortical neurons. Biol Pharm Bull 31: 149-153, 2008.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 149-153
-
-
Ban, J.Y.1
Nguyen, H.T.2
Lee, H.J.3
-
21
-
-
54049145466
-
DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway
-
Lin SS, Huang HP, Yang JS, et al: DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway. Cancer Lett 272: 77-90, 2008.
-
(2008)
Cancer Lett
, vol.272
, pp. 77-90
-
-
Lin, S.S.1
Huang, H.P.2
Yang, J.S.3
-
22
-
-
77955077389
-
Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways
-
Wu SH, Hang LW, Yang JS, et al: Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways. Anticancer Res 30: 2125-2133, 2010.
-
(2010)
Anticancer Res
, vol.30
, pp. 2125-2133
-
-
Wu, S.H.1
Hang, L.W.2
Yang, J.S.3
-
23
-
-
77954910401
-
MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
-
Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC and Chung JG: MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells. J Pharmacol Exp Ther 334: 477-488, 2010.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 477-488
-
-
Yang, J.S.1
Hour, M.J.2
Huang, W.W.3
Lin, K.L.4
Kuo, S.C.5
Chung, J.G.6
-
24
-
-
70349213747
-
Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo
-
Ji BC, Hsu WH, Yang JS, et al: Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo. J Agric Food Chem 57: 7596-7604, 2009.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 7596-7604
-
-
Ji, B.C.1
Hsu, W.H.2
Yang, J.S.3
-
25
-
-
78549252380
-
Improvement of lymphocyte resistance against H(2)O(2)-induced DNA damage in Sprague-Dawley rats after eight weeks of a wild blueberry (Vaccinium angustifolium)-enriched diet
-
Aug 26, Epub ahead of print
-
Del Bo C, Martini D, Vendrame S, et al: Improvement of lymphocyte resistance against H(2)O(2)-induced DNA damage in Sprague-Dawley rats after eight weeks of a wild blueberry (Vaccinium angustifolium)-enriched diet. Mutat Res: Aug 26, 2010 (Epub ahead of print).
-
(2010)
Mutat Res
-
-
Del Bo, C.1
Martini, D.2
Vendrame, S.3
-
26
-
-
61649124922
-
Effect of broccoli intake on markers related to oxidative stress and cancer risk in healthy smokers and nonsmokers
-
Riso P, Martini D, Visioli F, Martinetti A and Porrini M: Effect of broccoli intake on markers related to oxidative stress and cancer risk in healthy smokers and nonsmokers. Nutr Cancer 61: 232-237, 2009.
-
(2009)
Nutr Cancer
, vol.61
, pp. 232-237
-
-
Riso, P.1
Martini, D.2
Visioli, F.3
Martinetti, A.4
Porrini, M.5
-
27
-
-
0032907464
-
Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage?
-
Riso P, Pinder A, Santangelo A and Porrini M: Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage? Am J Clin Nutr 69: 712-718, 1999.
-
(1999)
Am J Clin Nutr
, vol.69
, pp. 712-718
-
-
Riso, P.1
Pinder, A.2
Santangelo, A.3
Porrini, M.4
-
28
-
-
77954648680
-
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells
-
Lu CC, Yang JS, Huang AC, et al: Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells. Mol Nutr Food Res 54: 967-976, 2010.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 967-976
-
-
Lu, C.C.1
Yang, J.S.2
Huang, A.C.3
-
29
-
-
60549088111
-
Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells
-
Chen JC, Lu KW, Tsai ML, et al: Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells. Oral Oncol 45: 273-283, 2009.
-
(2009)
Oral Oncol
, vol.45
, pp. 273-283
-
-
Chen, J.C.1
Lu, K.W.2
Tsai, M.L.3
-
30
-
-
77954165938
-
Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways
-
Lo C, Lai TY, Yang JH, et al: Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways. Int J Oncol 37: 377-385, 2010.
-
(2010)
Int J Oncol
, vol.37
, pp. 377-385
-
-
Lo, C.1
Lai, T.Y.2
Yang, J.H.3
-
31
-
-
34447277896
-
Strategies for the management of hepatocellular carcinoma
-
DOI 10.1038/ncponc0844, PII NCPONC0844
-
Schwartz M, Roayaie S and Konstadoulakis M: Strategies for the management of hepatocellular carcinoma. Nat Clin Pract Oncol 4: 424-432, 2007. (Pubitemid 47039693)
-
(2007)
Nature Clinical Practice Oncology
, vol.4
, Issue.7
, pp. 424-432
-
-
Schwartz, M.1
Roayaie, S.2
Konstadoulakis, M.3
-
32
-
-
42249104716
-
Efficacy of selected natural products as therapeutic agents against cancer
-
DOI 10.1021/np0705716
-
Banerjee S, Wang Z, Mohammad M, Sarkar FH and Mohammad RM: Efficacy of selected natural products as therapeutic agents against cancer. J Nat Prod 71: 492-496, 2008. (Pubitemid 351549382)
-
(2008)
Journal of Natural Products
, vol.71
, Issue.3
, pp. 492-496
-
-
Banerjee, S.1
Wang, Z.2
Mohammad, M.3
Sarkar, F.H.4
Mohammad, R.M.5
-
33
-
-
69449095860
-
Caspases and kinases in a death grip
-
Kurokawa M and Kornbluth S: Caspases and kinases in a death grip. Cell 138: 838-854, 2009.
-
(2009)
Cell
, vol.138
, pp. 838-854
-
-
Kurokawa, M.1
Kornbluth, S.2
-
34
-
-
68049143304
-
Apoptosis and cancer: Mutations within caspase genes
-
Ghavami S, Hashemi M, Ande SR, et al: Apoptosis and cancer: mutations within caspase genes. J Med Genet 46: 497-510, 2009.
-
(2009)
J Med Genet
, vol.46
, pp. 497-510
-
-
Ghavami, S.1
Hashemi, M.2
Ande, S.R.3
-
35
-
-
33845290596
-
Modeling mitochondrial function
-
Balaban RS: Modeling mitochondrial function. Am J Physiol Cell Physiol 291: C1107-C1113, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Balaban, R.S.1
-
36
-
-
70349251175
-
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist
-
Zaja-Milatovic S, Gupta RC, Aschner M and Milatovic D: Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist. Toxicol Appl Pharmacol 240: 124-131, 2009.
-
(2009)
Toxicol Appl Pharmacol
, vol.240
, pp. 124-131
-
-
Zaja-Milatovic, S.1
Gupta, R.C.2
Aschner, M.3
Milatovic, D.4
|