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Volumn 128, Issue 8, 2011, Pages 1935-1945

Identification of potential pharmacogenomic markers of clinical efficacy of 5-fluorouracil in colorectal cancer

Author keywords

5 fluorouracil; colorectal cancer; gene expression profiling; pharmacogenetics

Indexed keywords

FLUOROURACIL;

EID: 79951963847     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25514     Document Type: Article
Times cited : (21)

References (51)
  • 2
    • 33847244929 scopus 로고    scopus 로고
    • Drug resistance, predictive markers and pharmacogenomics in colorectal cancer
    • Longley DB, Allen WL, Johnston PG,. Drug resistance, predictive markers and pharmacogenomics in colorectal cancer. Biochim Biophys Acta 2006; 1766: 184-96.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 184-196
    • Longley, D.B.1    Allen, W.L.2    Johnston, P.G.3
  • 7
    • 0032950293 scopus 로고    scopus 로고
    • Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer
    • International Multicenter Pooled Analysis of B2 Colon Cancer Trial (IMPACT B2).
    • International Multicenter Pooled Analysis of B2 Colon Cancer Trial (IMPACT B2). Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. J Clin Oncol 1999; 17: 1356-63.
    • (1999) J Clin Oncol , vol.17 , pp. 1356-1363
  • 10
    • 67649304463 scopus 로고    scopus 로고
    • A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?
    • Koopman M, Venderbosch S, Nagtegaal ID, van Krieken JH, Punt CJ,. A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned? Eur J Cancer 2009; 45: 935-49.
    • (2009) Eur J Cancer , vol.45 , pp. 935-949
    • Koopman, M.1    Venderbosch, S.2    Nagtegaal, I.D.3    Van Krieken, J.H.4    Punt, C.J.5
  • 12
    • 17644373059 scopus 로고    scopus 로고
    • Variance in the expression of 5-fluorouracil pathway genes in colorectal cancer
    • DOI 10.1158/1078-0432.CCR-04-1258
    • Kidd EA, Yu J, Li X, Shannon WD, Watson MA, McLeod HL,. Variance in the expression of 5-fluorouracil pathway genes in colorectal cancer. Clin Cancer Res 2005; 11: 2612-19. (Pubitemid 40569461)
    • (2005) Clinical Cancer Research , vol.11 , Issue.7 , pp. 2612-2619
    • Kidd, E.A.1    Yu, J.2    Li, X.3    Shannon, W.D.4    Watson, M.A.5    McLeod, H.L.6
  • 14
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L,. Gene-expression signatures in breast cancer. N Engl J Med 2009; 360: 790-800.
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 15
    • 1442290323 scopus 로고    scopus 로고
    • Thymidylate-synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
    • DOI 10.1200/JCO.2004.05.064
    • Popat S, Matakidou A, Houlston RS,. Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. J Clin Oncol 2004; 22: 529-36. (Pubitemid 41079782)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.3 , pp. 529-536
    • Popat, S.1    Matakidou, A.2    Houlston, R.S.3
  • 19
    • 67649304464 scopus 로고    scopus 로고
    • Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study
    • Koopman M, Venderbosch S, van Tinteren H, Ligtenberg MJ, Nagtegaal I, Van Krieken JH, Punt CJ,. Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study. Eur J Cancer 2009; 45: 1999-2006.
    • (2009) Eur J Cancer , vol.45 , pp. 1999-2006
    • Koopman, M.1    Venderbosch, S.2    Van Tinteren, H.3    Ligtenberg, M.J.4    Nagtegaal, I.5    Van Krieken, J.H.6    Punt, C.J.7
  • 21
    • 29844453626 scopus 로고    scopus 로고
    • Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase
    • DOI 10.1093/annonc/mdj046
    • Smorenburg CH, Peters GJ, van Groeningen CJ, Noordhuis P, Smid K, van Riel AM, Dercksen W, Pinedo HM, Giaccone G,. Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase. Ann Oncol 2006; 17: 35-42. (Pubitemid 43033837)
    • (2006) Annals of Oncology , vol.17 , Issue.1 , pp. 35-42
    • Smorenburg, C.H.1    Peters, G.J.2    Van Groeningen, C.J.3    Noordhuis, P.4    Smid, K.5    Van Riel, A.M.G.H.6    Dercksen, W.7    Pinedo, H.M.8    Giaccone, G.9
  • 22
    • 33745076752 scopus 로고    scopus 로고
    • Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: Three-gene expression model predicts clinical response
    • Matsuyama R, Togo S, Shimizu D, Momiyama N, Ishikawa T, Ichikawa Y, Endo I, Kunisaki C, Suzuki H, Hayasizaki Y, Shimada H,. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response. Int J Cancer 2006; 119: 406-13.
    • (2006) Int J Cancer , vol.119 , pp. 406-413
    • Matsuyama, R.1    Togo, S.2    Shimizu, D.3    Momiyama, N.4    Ishikawa, T.5    Ichikawa, Y.6    Endo, I.7    Kunisaki, C.8    Suzuki, H.9    Hayasizaki, Y.10    Shimada, H.11
  • 23
    • 58749116650 scopus 로고    scopus 로고
    • Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: MRNA expression for 18 chemotherapy-related genes
    • Gustavsson B, Kaiser C, Carlsson G, Wettergren Y, Odin E, Lindskog EB, Niyikiza C, Ma D,. Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: mRNA expression for 18 chemotherapy-related genes. Int J Cancer 2009; 124: 1220-6.
    • (2009) Int J Cancer , vol.124 , pp. 1220-1226
    • Gustavsson, B.1    Kaiser, C.2    Carlsson, G.3    Wettergren, Y.4    Odin, E.5    Lindskog, E.B.6    Niyikiza, C.7    Ma, D.8
  • 24
    • 0029644482 scopus 로고
    • Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
    • International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators.
    • International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 1995; 345: 939-44.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 25
    • 0027482012 scopus 로고
    • Resistance to fluorodeoxyuridine-induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate
    • Canman CE, Lawrence TS, Shewach DS, Tang HY, Maybaum J,. Resistance to fluorodeoxyuridine-induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate. Cancer Res 1993; 53: 5219-24. (Pubitemid 23333391)
    • (1993) Cancer Research , vol.53 , Issue.21 , pp. 5219-5224
    • Canman, C.E.1    Lawrence, T.S.2    Shewach, D.S.3    Tang, H.-Y.4    Maybaum, J.5
  • 26
    • 0037063173 scopus 로고    scopus 로고
    • Novel gain of function activity of p53 mutants: Activation of the dUTPase gene expression leading to resistance to 5-fluorouracil
    • DOI 10.1038/sj.onc.1205704
    • Pugacheva EN, Ivanov AV, Kravchenko JE, Kopnin BP, Levine AJ, Chumakov PM,. Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil. Oncogene 2002; 21: 4595-600. (Pubitemid 34833137)
    • (2002) Oncogene , vol.21 , Issue.30 , pp. 4595-4600
    • Pugacheva, E.N.1    Ivanov, A.V.2    Kravchenko, J.E.3    Kopnin, B.P.4    Levine, A.J.5    Chumakov, P.M.6
  • 27
    • 0034234872 scopus 로고    scopus 로고
    • DUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: Association with survival and response to 5-fluorouracil in colorectal cancer
    • Ladner RD, Lynch FJ, Groshen S, Xiong YP, Sherrod A, Caradonna SJ, Stoehlmacher J, Lenz HJ,. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer. Cancer Res 2000; 60: 3493-503. (Pubitemid 30482169)
    • (2000) Cancer Research , vol.60 , Issue.13 , pp. 3493-3503
    • Ladner, R.D.1    Lynch, F.J.2    Groshen, S.3    Xiong, Y.P.4    Sherrod, A.5    Caradonna, S.J.6    Stoehlmacher, J.7    Lenz, H.-J.8
  • 29
    • 30144433850 scopus 로고    scopus 로고
    • Locus-specific mutation databases: Pitfalls and good practice based on the p53 experience
    • DOI 10.1038/nrc1783
    • Soussi T, Ishioka C, Claustres M, Béroud C,. Locus-specific mutation databases: pitfalls and good practice based on the p53 experience. Nat Rev Cancer 2006; 6: 83-90. (Pubitemid 43053654)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 83-90
    • Soussi, T.1    Ishioka, C.2    Claustres, M.3    Beroud, C.4
  • 32
    • 25444481030 scopus 로고    scopus 로고
    • Effect of p53 status and STAT1 on chemotherapy-induced, fas-mediated apoptosis in colorectal cancer
    • DOI 10.1158/0008-5472.CAN-05-0961
    • McDermott U, Longley DB, Galligan L, Allen W, Wilson T, Johnston PG,. Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. Cancer Res 2005; 65: 8951-60. (Pubitemid 41377386)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8951-8960
    • McDermott, U.1    Longley, D.B.2    Galligan, L.3    Allen, W.4    Wilson, T.5    Johnston, P.G.6
  • 33
    • 15244362062 scopus 로고    scopus 로고
    • P53 abnormalities and outcomes in colorectal cancer: A systematic review
    • DOI 10.1038/sj.bjc.6602358
    • Munro AJ, Lain S, Lane DP,. P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer 2005; 92: 434-44. (Pubitemid 40395523)
    • (2005) British Journal of Cancer , vol.92 , Issue.3 , pp. 434-444
    • Munro, A.J.1    Lain, S.2    Lane, D.P.3
  • 35
    • 0034895979 scopus 로고    scopus 로고
    • P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
    • Elsaleh H, Powell B, McCaul K, Grieu F, Grant R, Joseph D, Iacopetta B,. P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin Cancer Res 2001; 7: 1343-9. (Pubitemid 32708690)
    • (2001) Clinical Cancer Research , vol.7 , Issue.5 , pp. 1343-1349
    • Elsaleh, H.1    Powell, B.2    McCaul, K.3    Grieu, F.4    Grant, R.5    Joseph, D.6    Iacopetta, B.7
  • 38
    • 0037126392 scopus 로고    scopus 로고
    • The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis
    • DOI 10.1038/sj.onc.1205862
    • Liu G, Chen X,. The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis. Oncogene 2002; 21: 7195-204. (Pubitemid 35305606)
    • (2002) Oncogene , vol.21 , Issue.47 , pp. 7195-7204
    • Liu, G.1    Chen, X.2
  • 39
    • 0141954046 scopus 로고    scopus 로고
    • Ferredoxin reductase: Pharmacogenomic assessment in colorectal cancer
    • Yu J, Marsh S, Ahluwalia R, McLeod HL,. Ferredoxin reductase: pharmacogenomic assessment in colorectal cancer. Cancer Res 2003; 63: 6170-3. (Pubitemid 37255159)
    • (2003) Cancer Research , vol.63 , Issue.19 , pp. 6170-6173
    • Yu, J.1    Marsh, S.2    Ahluwalia, R.3    McLeod, H.L.4
  • 40
    • 33748475139 scopus 로고    scopus 로고
    • Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin
    • DOI 10.1007/s00280-006-0217-6
    • Ichikawa W, Ooyama A, Toda E, Sugimoto Y, Oka T, Takahashi T, Shimizu M, Sasaki Y, Hirayama R,. Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin. Cancer Chemother Pharmacol 2006; 58: 794-801. (Pubitemid 44351260)
    • (2006) Cancer Chemotherapy and Pharmacology , vol.58 , Issue.6 , pp. 794-801
    • Ichikawa, W.1    Ooyama, A.2    Toda, E.3    Sugimoto, Y.4    Oka, T.5    Takahashi, T.6    Shimizu, M.7    Sasaki, Y.8    Hirayama, R.9
  • 41
    • 0034930961 scopus 로고    scopus 로고
    • Nm23 protein expression in colorectal carcinoma metastasis in regional lymph nodes and the liver
    • DOI 10.1053/ejso.2000.1070
    • Sarris M, Lee CS,. nm23 protein expression in colorectal carcinoma metastasis in regional lymph nodes and the liver. Eur J Surg Oncol 2001; 27: 170-4. (Pubitemid 32621730)
    • (2001) European Journal of Surgical Oncology , vol.27 , Issue.2 , pp. 170-174
    • Sarris, M.1    Lee, C.S.2
  • 42
    • 13844299981 scopus 로고    scopus 로고
    • Prognostic significance of nm23 gene product expression in patients with colorectal carcinoma treated with radical intent
    • Soliani P, Ziegler S, Romani A, Corcione L, Campanini N, Dell′Abate P, Del Rio P, Sianesi M,. Prognostic significance of nm23 gene product expression in patients with colorectal carcinoma treated with radical intent. Oncol Rep 2004; 11: 1193-200.
    • (2004) Oncol Rep , vol.11 , pp. 1193-1200
    • Soliani, P.1    Ziegler, S.2    Romani, A.3    Corcione, L.4    Campanini, N.5    Dellabate, P.6    Del Rio, P.7    Sianesi, M.8
  • 43
    • 0036796917 scopus 로고    scopus 로고
    • Prognostic implication of nm23-H1 expression in colorectal carcinomas
    • DOI 10.1080/0031302021000009342
    • Dursun A, Akyürek N, Günel N, Yamaà D,. Prognostic implication of nm23-H1 expression in colorectal carcinomas. Pathology 2002; 34: 427-32. (Pubitemid 35205244)
    • (2002) Pathology , vol.34 , Issue.5 , pp. 427-432
    • Dursun, A.1    Akyurek, N.2    Gunel, N.3    Yamac, D.4
  • 44
    • 0031917961 scopus 로고    scopus 로고
    • Overexpression of nm23 protein assessed by color video image analysis in metastatic colorectal cancer: Correlation with reduced patient survival
    • DOI 10.1007/s002689900421
    • Berney CR, Yang JL, Fisher RJ, Russell PJ, Crowe PJ,. Overexpression of nm23 protein assessed by color video image analysis in metastatic colorectal cancer: correlation with reduced patient survival. World J Surg 1998; 22: 484-90. (Pubitemid 28169606)
    • (1998) World Journal of Surgery , vol.22 , Issue.5 , pp. 484-490
    • Berney, C.R.1    Yang, J.-L.2    Fisher, R.J.3    Russell, P.J.4    Crowe, P.J.5
  • 47
    • 0036534108 scopus 로고    scopus 로고
    • Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy
    • DOI 10.1200/JCO.2002.07.039
    • Edler D, Glimelius B, Hallström M, Jakobsen A, Johnston PG, Magnusson I, Ragnhammar P, Blomgren H,. Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. J Clin Oncol 2002; 20: 1721-8. (Pubitemid 34273259)
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.7 , pp. 1721-1728
    • Edler, D.1    Glimelius, B.2    Hallstrom, M.3    Jakobsen, A.4    Johnston, P.G.5    Magnusson, I.6    Ragnhammar, P.7    Blomgren, H.8
  • 48
    • 0033995850 scopus 로고    scopus 로고
    • Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
    • Takenoue T, Nagawa H, Matsuda K, Fujii S, Nita ME, Hatano K, Kitayama J, Tsuruo T, Muto T,. Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 2000; 7: 193-8. (Pubitemid 30215157)
    • (2000) Annals of Surgical Oncology , vol.7 , Issue.3 , pp. 193-198
    • Takenoue, T.1    Nagawa, H.2    Matsuda, K.3    Fujii, S.4    Nita, M.E.5    Hatano, K.6    Kitayama, J.7    Tsuruo, T.8    Muto, T.9
  • 49
    • 0031941249 scopus 로고    scopus 로고
    • A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
    • DOI 10.1002/(SIC I)1097-0142(19 980101)82:1<70 ::AID-CNCR8>3.0. CO;2-O
    • Yamachika T, Nakanishi H, Inada K, Tsukamoto T, Kato T, Fukushima M, Inoue M, Tatematsu M,. A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 1998; 82: 70-7. (Pubitemid 28070481)
    • (1998) Cancer , vol.82 , Issue.1 , pp. 70-77
    • Yamachika, T.1    Nakanishi, H.2    Inada, K.-I.3    Tsukamoto, T.4    Kato, T.5    Fukushima, M.6    Inoue, M.7    Tatematsu, M.8
  • 50
    • 0034885982 scopus 로고    scopus 로고
    • Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo
    • DOI 10.1016/S0959-8049(01)00174-5, PII S0959804901001745
    • Fukushima M, Fujioka A, Uchida J, Nakagawa F, Takechi T,. Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo. Eur J Cancer 2001; 37: 1681-7. (Pubitemid 32778616)
    • (2001) European Journal of Cancer , vol.37 , Issue.13 , pp. 1681-1687
    • Fukushima, M.1    Fujioka, A.2    Uchida, J.3    Nakagawa, F.4    Takechi, T.5
  • 51
    • 0036875483 scopus 로고    scopus 로고
    • Different pathways of 5-fluorouracil metabolism after continuous venous or bolus injection in patients with colon carcinoma: Possible predictive value of thymidylate synthetase mRNA and ribonucleotide reductase for 5-fluorouracil sensitivity
    • Kubota T, Watanabe M, Otani Y, Kitajima M, Fukushiuma M,. Different pathways of 5-fluorouracil metabolism after continuous venous or bolus injection in patients with colon carcinoma: possible predictive value of thymidylate synthetase mRNA and ribonucleotide reductase for 5-fluorouracil sensitivity. Anticancer Res 2002; 22: 3537-40. (Pubitemid 36132825)
    • (2002) Anticancer Research , vol.22 , pp. 3537-3540
    • Kubota, T.1    Watanabe, M.2    Otani, Y.3    Kitajima, M.4    Fukushiuma, M.5


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