Different pathways of 5-fluorouracil metabolism after continuous venous or bolus injection in patients with colon carcinoma: Possible predictive value of thymidylate synthetase mRNA and ribonucleotide reductase for 5-fluorouracil sensitivity

Anticancer Research

Volumn 22, Issue 6 B, 2002, Pages 3537-3540

  Kubota, Tetsuro ^a   Watanabe, Masahiko ^a   Otani, Yoshihide ^a   Kitajima, Masaki ^a   Fukushiuma, Masakazu ^b  

^a KEIO UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

5 Fluorouracil; Colon cancer; Ribonucleotide reductase; Sensitivity; Thymidylate synthetase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BROMINE DERIVATIVE; FLUOROURACIL; MESSENGER RNA; RIBONUCLEOTIDE REDUCTASE; THYMIDYLATE SYNTHASE;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COLON CARCINOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

COLONIC NEOPLASMS; FLUOROURACIL; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAVENOUS; PREDICTIVE VALUE OF TESTS; RIBONUCLEOTIDE REDUCTASES; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES; THYMIDYLATE SYNTHASE;

EID: 0036875483     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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