-
1
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
Longley, D. B., Harkin, D. P., and Johnston, P. G. 5-fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer, 3: 330-338, 2003.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
2
-
-
0037303731
-
Oral chemotherapy in colorectal cancer treatment: Review of the literature
-
Kurtz, J. E., Andres, E., Natarajan-Ame, S., Noel, E., and Dufour, P. Oral chemotherapy in colorectal cancer treatment: review of the literature. Eur. J. Intern. Med., 14: 18-25, 2003.
-
(2003)
Eur. J. Intern. Med.
, vol.14
, pp. 18-25
-
-
Kurtz, J.E.1
Andres, E.2
Natarajan-Ame, S.3
Noel, E.4
Dufour, P.5
-
3
-
-
0034775927
-
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
-
Hwang, P. M., Bunz, F., Yu, J., Rago, C., Chan, T. A., Murphy, M. P., Kelso, G. F., Smith, R. A., Kinzler, K. W., and Vogelstein, B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nat. Med., 7: 1111-1117, 2001.
-
(2001)
Nat. Med.
, vol.7
, pp. 1111-1117
-
-
Hwang, P.M.1
Bunz, F.2
Yu, J.3
Rago, C.4
Chan, T.A.5
Murphy, M.P.6
Kelso, G.F.7
Smith, R.A.8
Kinzler, K.W.9
Vogelstein, B.10
-
4
-
-
0037126392
-
The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis
-
Liu, G., and Chen, X. The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis. Oncogene, 21: 7195-7204, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 7195-7204
-
-
Liu, G.1
Chen, X.2
-
5
-
-
0035951779
-
Adrenodoxin reductase-adrenodoxin complex structure suggests electron transfer path in steroid biosynthesis
-
Muller, J. J., Lapko, A., Bourenkov, G., Ruckpaul, K., and Heinemann, U. Adrenodoxin reductase-adrenodoxin complex structure suggests electron transfer path in steroid biosynthesis. J. Biol. Chem., 276: 2786-2789, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2786-2789
-
-
Muller, J.J.1
Lapko, A.2
Bourenkov, G.3
Ruckpaul, K.4
Heinemann, U.5
-
6
-
-
0027328115
-
Electron leakage from the mitochondrial NADPH-adrenodoxin reductase-adrenodoxin-P450scc (cholesterol side chain cleavage) system
-
Hanukoglu, I., Rapoport, R., Weiner, L., and Sklan, D. Electron leakage from the mitochondrial NADPH-adrenodoxin reductase-adrenodoxin-P450scc (cholesterol side chain cleavage) system. Arch. Biochem. Biophys., 305: 489-498, 1993.
-
(1993)
Arch. Biochem. Biophys.
, vol.305
, pp. 489-498
-
-
Hanukoglu, I.1
Rapoport, R.2
Weiner, L.3
Sklan, D.4
-
7
-
-
0028923332
-
Electron leakage from the adrenal cortex mitochondial P450scc and P450c11 systems: NADPH and steroid dependence
-
Rapoport, R., Sklan, D., and Hanukoglu, I. Electron leakage from the adrenal cortex mitochondial P450scc and P450c11 systems: NADPH and steroid dependence. Arch. Biochem. Biophys., 317: 412-416, 1995.
-
(1995)
Arch. Biochem. Biophys.
, vol.317
, pp. 412-416
-
-
Rapoport, R.1
Sklan, D.2
Hanukoglu, I.3
-
8
-
-
0141565216
-
Cancer pharmacogenomics: SNPs, chips, and the individual patient
-
McLeod, H. L., and Yu, J. Cancer pharmacogenomics: SNPs, chips, and the individual patient. Cancer Investig., 21: 628-638, 2003.
-
(2003)
Cancer Investig.
, vol.21
, pp. 628-638
-
-
McLeod, H.L.1
Yu, J.2
-
9
-
-
0037451804
-
Cancer pharmacogenomics: Current and future applications
-
Watters, J. W., and McLeod, H. L. Cancer pharmacogenomics: current and future applications. Biochem. Biophys. Acta, 1603: 99-111, 2003.
-
(2003)
Biochem. Biophys. Acta
, vol.1603
, pp. 99-111
-
-
Watters, J.W.1
McLeod, H.L.2
-
10
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, M. W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res., 29: 2002-2007, 2001.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2002-2007
-
-
Pfaffl, M.W.1
-
11
-
-
0035576102
-
ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
-
Shirota, Y., Stoehlmacher, J., Brabender, J., Xiong, Y. P., Uetake, H., Danenberg, K. D., Groshen, S., Tsao-Wei, D. D., Danenberg, P. V., and Lenz, H. J. ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J. Clin. Oncol., 19: 4298-4304, 2001.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 4298-4304
-
-
Shirota, Y.1
Stoehlmacher, J.2
Brabender, J.3
Xiong, Y.P.4
Uetake, H.5
Danenberg, K.D.6
Groshen, S.7
Tsao-Wei, D.D.8
Danenberg, P.V.9
Lenz, H.J.10
-
12
-
-
0032706622
-
Analysis of human transcriptomes
-
Velculescu, V. E., Madden, S. L., Zhang, L., Lash, A. E., Yu, J., Rago, C., Lal, A., Wang, C. J., Beaudry, G. A., Ciriello, K. M., Cook, B. P., Dufault, M. R., Ferguson, A. T., Gao, Y., He, T. C., Hermeking, H., Hiraldo, S. K., Hwang, P. M., Lopez, M. A., Luderer, H. F., Mathews, B., Petroziello, J. M., Polyak, K., Zawel, L., Zhang, W., Zhang, X., Zhou, W., Haluska, F. G., Jen, J., Sukumar, S., Landes, G. M., Riggins, G. J., Vogelstein, B., and Kinzler, K. W. Analysis of human transcriptomes. Nat. Genet., 23: 387-388, 1999.
-
(1999)
Nat. Genet.
, vol.23
, pp. 387-388
-
-
Velculescu, V.E.1
Madden, S.L.2
Zhang, L.3
Lash, A.E.4
Yu, J.5
Rago, C.6
Lal, A.7
Wang, C.J.8
Beaudry, G.A.9
Ciriello, K.M.10
Cook, B.P.11
Dufault, M.R.12
Ferguson, A.T.13
Gao, Y.14
He, T.C.15
Hermeking, H.16
Hiraldo, S.K.17
Hwang, P.M.18
Lopez, M.A.19
Luderer, H.F.20
Mathews, B.21
Petroziello, J.M.22
Polyak, K.23
Zawel, L.24
Zhang, W.25
Zhang, X.26
Zhou, W.27
Haluska, F.G.28
Jen, J.29
Sukumar, S.30
Landes, G.M.31
Riggins, G.J.32
Vogelstein, B.33
Kinzler, K.W.34
more..
-
13
-
-
0036024997
-
SNP databases and pharmacogenetics: Great start but a long way to go
-
Marsh, S., Kwok, P., and McLeod, H. L. SNP databases and pharmacogenetics: great start but a long way to go. Hum. Mutat., 20: 174-179, 2002.
-
(2002)
Hum. Mutat.
, vol.20
, pp. 174-179
-
-
Marsh, S.1
Kwok, P.2
McLeod, H.L.3
-
14
-
-
0035153070
-
Pyrosequencing sheds light on DNA sequencing
-
Ronaghi, M. Pyrosequencing sheds light on DNA sequencing. Genome Res., 11: 3-11, 2001.
-
(2001)
Genome Res.
, vol.11
, pp. 3-11
-
-
Ronaghi, M.1
-
15
-
-
0036782136
-
Caution on pedigree haplotype inference with software that assumes linkage equilibrium
-
Schaid, D. J., McDonnell, S. K., Wang, L., Cunningham, J. M., and Thibodeau, S. N. Caution on pedigree haplotype inference with software that assumes linkage equilibrium. Am. J. Hum. Genet., 71: 992-995, 2002.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 992-995
-
-
Schaid, D.J.1
McDonnell, S.K.2
Wang, L.3
Cunningham, J.M.4
Thibodeau, S.N.5
-
16
-
-
0033579412
-
Regulation of the p53 tumor suppressor protein
-
Oren, M. Regulation of the p53 tumor suppressor protein. J. Biol. Chem., 274: 36031-36034, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36031-36034
-
-
Oren, M.1
-
17
-
-
0033609306
-
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity
-
Unger, T., Sionov, R. V., Moallem, E., Yee, C. L., Howley, P. M., Oren, M., and Haupt, Y. Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. Oncogene, 18: 3205-3212, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 3205-3212
-
-
Unger, T.1
Sionov, R.V.2
Moallem, E.3
Yee, C.L.4
Howley, P.M.5
Oren, M.6
Haupt, Y.7
-
18
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe, S. W., Bodis, S., McClatchey, A., Remington, L., Ruley, H. E., Fisher, D. E., Housman, D. E., and Jacks, T. p53 status and the efficacy of cancer therapy in vivo. Science (Wash. DC), 266: 807-810, 1994.
-
(1994)
Science (Wash. DC)
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
19
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
LeBlanc, H., Lawrence, D., Varfolomeev, E., Totpal, K., Morlan, J., Schow, P., Fong, S., Schwall, R., Sinicropi, D., and Ashkenazi, A. Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat. Med., 8: 274-281, 2002.
-
(2002)
Nat. Med.
, vol.8
, pp. 274-281
-
-
LeBlanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
Fong, S.7
Schwall, R.8
Sinicropi, D.9
Ashkenazi, A.10
-
20
-
-
0032191655
-
Inhibition of TP53-dependent apoptosis by the KIT tyrosine kinase: Regulation of mitochondrial permeability transition and reactive oxygen species generation
-
Lee, J. M. Inhibition of TP53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene, 17: 1653-1662, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 1653-1662
-
-
Lee, J.M.1
-
21
-
-
0033229866
-
TP53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
-
Li, P. F., Dietz, R., and von Harsdorf, R. TP53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J., 18: 6027-6036, 1999.
-
(1999)
EMBO J.
, vol.18
, pp. 6027-6036
-
-
Li, P.F.1
Dietz, R.2
Von Harsdorf, R.3
-
22
-
-
0036533524
-
Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and TP53 status
-
Violette, S., Poulain, L., Dussaulx, E., Pepin, D., Faussat, A. M., Chambaz, J., Lacorte, J. M., Staedel, C., and Lesuffleur, T. Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and TP53 status. Int. J. Cancer, 98: 498-504, 2002.
-
(2002)
Int. J. Cancer
, vol.98
, pp. 498-504
-
-
Violette, S.1
Poulain, L.2
Dussaulx, E.3
Pepin, D.4
Faussat, A.M.5
Chambaz, J.6
Lacorte, J.M.7
Staedel, C.8
Lesuffleur, T.9
-
23
-
-
0034641736
-
Complex promoter and coding region β2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
-
Drysdale, C. M., McGraw, D. W., Stack, C. B., Stephens, J. C., Judson, R. S., Nandabalan, K., Arnold, K., Ruano, G., and Liggett, S. B. Complex promoter and coding region β2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness. Proc. Natl. Acad. Sci. USA, 97: 10483-10488, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10483-10488
-
-
Drysdale, C.M.1
McGraw, D.W.2
Stack, C.B.3
Stephens, J.C.4
Judson, R.S.5
Nandabalan, K.6
Arnold, K.7
Ruano, G.8
Liggett, S.B.9
|