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Volumn 38, Issue SUPPL. 11, 2011, Pages 106-113

What can the periodontal community learn from the pathophysiology of rheumatoid arthritis?

Author keywords

Bone destruction; Host response; Periodontitis; Rheumatoid arthritis

Indexed keywords

AUTACOID; CYTOKINE; IMMUNOSUPPRESSIVE AGENT;

EID: 79951897523     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2010.01669.x     Document Type: Conference Paper
Times cited : (42)

References (75)
  • 1
    • 0033227874 scopus 로고    scopus 로고
    • Position paper: Tobacco use and the periodontal patient
    • AAP Position Paper
    • AAP Position Paper. (1999) Position paper: tobacco use and the periodontal patient. Journal of Periodontology 70, 1419-1427.
    • (1999) Journal of Periodontology , vol.70 , pp. 1419-1427
  • 2
    • 0027450276 scopus 로고
    • 1-antichymotrypsin by neutrophils in arthritic joints
    • Abbink, J. J., Kamp, A. M., Nuijens, J. H., Swaak, T. J. & Hack, C. E. (1993) Proteolytic inactivation of alpha 1-antitrypsin and alpha 1-antichymotrypsin by neutrophils in arthritic joints. Arthritis & Rheumatism 36, 168-180. (Pubitemid 23059327)
    • (1993) Arthritis and Rheumatism , vol.36 , Issue.2 , pp. 168-180
    • Abbink, J.J.1    Kamp, A.M.2    Nuijens, J.H.3    Swaak, T.J.G.4    Hack, C.E.5
  • 3
    • 47249089097 scopus 로고    scopus 로고
    • IL-1, IL- 18, and IL-33 families of cytokines
    • Arend, W. P., Palmer, G. & Gabay, C. (2008) IL-1, IL- 18, and IL-33 families of cytokines. Immunological Reviews 223, 20-38.
    • (2008) Immunological Reviews , vol.223 , pp. 20-38
    • Arend, W.P.1    Palmer, G.2    Gabay, C.3
  • 4
    • 73349089655 scopus 로고    scopus 로고
    • Rheumatoid arthritis and smoking: Putting the pieces together
    • Baka, Z., Buzas, E. & Nagy, G. (2009) Rheumatoid arthritis and smoking: putting the pieces together. Arthritis Research and Therapy 11, 238.
    • (2009) Arthritis Research and Therapy , vol.11 , pp. 238
    • Baka, Z.1    Buzas, E.2    Nagy, G.3
  • 5
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis
    • Bartok, B. & Firestein, G. S. (2010) Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunological Reviews 233, 233-255.
    • (2010) Immunological Reviews , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 7
    • 0024314554 scopus 로고
    • Inhibitory effect of TNFalpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan, F. M., Chantry, D., Jackson, A., Maini, R. & Feldmann, M. (1989) Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 2, 244-247. (Pubitemid 19180612)
    • (1989) Lancet , vol.2 , Issue.8657 , pp. 244-247
    • Brennan, F.M.1    Jackson, A.2    Chantry, D.3    Maini, R.4    Feldmann, M.5
  • 8
    • 55849095891 scopus 로고    scopus 로고
    • Evidence that cytokines play a role in rheumatoid arthritis
    • Brennan, F. M. & McInnes, I. B. (2008) Evidence that cytokines play a role in rheumatoid arthritis. The Journal of Clinical Investigation 118, 3537-3545.
    • (2008) The Journal of Clinical Investigation , vol.118 , pp. 3537-3545
    • Brennan, F.M.1    McInnes, I.B.2
  • 9
    • 33745900256 scopus 로고    scopus 로고
    • Bisphosphonate therapy in rheumatoid arthritis
    • Breuil, V. & Euller-Ziegler, L. (2006) Bisphosphonate therapy in rheumatoid arthritis. Joint Bone Spine 73, 349-354.
    • (2006) Joint Bone Spine , vol.73 , pp. 349-354
    • Breuil, V.1    Euller-Ziegler, L.2
  • 11
    • 33144472845 scopus 로고    scopus 로고
    • Epstein- Barr virus and rheumatoid arthritis: Is there a link?
    • Costenbader, K. H. & Karlson, E. W. (2006) Epstein- Barr virus and rheumatoid arthritis: is there a link? Arthritis Research and Therapy 8, 204.
    • (2006) Arthritis Research and Therapy , vol.8 , pp. 204
    • Costenbader, K.H.1    Karlson, E.W.2
  • 13
    • 33745010247 scopus 로고    scopus 로고
    • Signalling pathways in B cells: Implications for autoimmunity
    • Current Concepts in Autoimmunity and Chronic Inflammation
    • Dorner, T. & Lipsky, P. E. (2006) Signalling pathways in B cells: implications for autoimmunity. Current Topics in Microbiology and Immunology 305, 213-240. (Pubitemid 47400260)
    • (2006) Current Topics in Microbiology and Immunology , vol.305 , pp. 213-240
    • Dorner, T.1    Lipsky, P.E.2
  • 16
    • 0030737716 scopus 로고    scopus 로고
    • Seeing the wood for the trees: The forgotten role of neutrophils in rheumatoid arthritis
    • DOI 10.1016/S0167-5699(97)01087-6
    • Edwards, S. W. & Hallett, M. B. (1997) Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis. Immunology Today 18, 320-324. (Pubitemid 27314467)
    • (1997) Immunology Today , vol.18 , Issue.7 , pp. 320-324
    • Edwards, S.W.1    Hallett, M.B.2
  • 17
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
    • DOI 10.1084/jem.20040165
    • Ehrenstein, M. R., Evans, J. G., Singh, A., Moore, S., Warnes, G., Isenberg, D. A. & Mauri, C. (2004) Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. Journal of Experimental Medicine 200, 277-285. (Pubitemid 39031247)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.3 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 18
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • DOI 10.1016/S0140-6736(94)90628-9
    • Elliott, M. J., Maini, R. N., Feldmann, M., Kalden, J. R., Antoni, C., Smolen, J. S., Leeb, B., Breedveld, F. C., Macfarlane, J. D., Bijl, J. A. & Woody, J. N. (1994) Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor [alpha] (cA2) versus placebo in rheumatoid arthritis. The Lancet 344, 1105-1110. (Pubitemid 24317629)
    • (1994) Lancet , vol.344 , Issue.8930 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Kalden, J.R.4    Antoni, C.5    Smolen, J.S.6    Leeb, B.7    Breedveld, F.C.8    Macfarlane, J.D.9    Bijl, H.10    Woody, J.N.11
  • 19
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
    • Emery, P., Roy, F., Anna, F.-S., Joy, S., Leszek, S., Arthur, K., Artur, J. R., Ronald, F. v. V., Nicole, F. L., Sunil, A., Eva, W. H., Timothy, M. S. & Group, D. S. (2006) The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis & Rheumatism 54, 1390-1400.
    • (2006) Arthritis & Rheumatism , vol.54 , pp. 1390-1400
    • Emery, P.1    Roy, F.2    Anna, F.-S.3    Joy, S.4    Leszek, S.5    Arthur, K.6    Artur, J.R.7    Ronald, F.V.V.8    Nicole, F.L.9    Sunil, A.10    Eva, W.H.11    Timothy, M.S.12    Group, D.S.13
  • 20
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • Firestein, G. S. (2003) Evolving concepts of rheumatoid arthritis. Nature 423, 356-361.
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 21
    • 27444444992 scopus 로고    scopus 로고
    • Updated consensus statement on biological agents, specifically tumour necrosis factor {alpha} (TNF{alpha}) blocking agents and interleukin- 1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2005
    • Furst, D. E., Breedveld, F. C., Kalden, J. R., Smolen, J. S., Burmester, G. R., Bijlsma, J. W., Dougados, M., Emery, P., Keystone, E. C., Klareskog, L. & Mease, P. J. (2005) Updated consensus statement on biological agents, specifically tumour necrosis factor {alpha} (TNF{alpha}) blocking agents and interleukin- 1 receptor antagonist (IL-1ra), for the treatment of rheumatic diseases, 2005. Annals of the Rheumatic Diseases 64 (Suppl. 4), iv2-iv14.
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.SUPPL. 4
    • Furst, D.E.1    Breedveld, F.C.2    Kalden, J.R.3    Smolen, J.S.4    Burmester, G.R.5    Bijlsma, J.W.6    Dougados, M.7    Emery, P.8    Keystone, E.C.9    Klareskog, L.10    Mease, P.J.11
  • 23
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized antiinterleukin- 17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • Genovese, M. C., Van den Bosch, F., Roberson, S. A., Bojin, S., Biagini, I. M., Ryan, P. & Sloan-Lancaster, J. (2010) LY2439821, a humanized antiinterleukin- 17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis & Rheumatism 62, 929-939.
    • (2010) Arthritis & Rheumatism , vol.62 , pp. 929-939
    • Genovese, M.C.1    Van Den Bosch, F.2    Roberson, S.A.3    Bojin, S.4    Biagini, I.M.5    Ryan, P.6    Sloan-Lancaster, J.7
  • 25
    • 0026025865 scopus 로고
    • Oxidative damage to hyaluronate and glucose in synovial fluid during exercise of the inflamed rheumatoid joint. Detection of abnormal low-molecular-mass metabolites by proton-n.m.r. spectroscopy
    • Grootveld, M., Henderson, E. B., Farrell, A., Blake, D. R., Parkes, H. G. & Haycock, P. (1991) Oxidative damage to hyaluronate and glucose in synovial fluid during exercise of the inflamed rheumatoid joint. Detection of abnormal low-molecular-mass metabolites by proton-n.m.r. spectroscopy. Biochemical Journal 273 (Part 2), 459-467.
    • (1991) Biochemical Journal , vol.273 , Issue.PART 2 , pp. 459-467
    • Grootveld, M.1    Henderson, E.B.2    Farrell, A.3    Blake, D.R.4    Parkes, H.G.5    Haycock, P.6
  • 28
    • 73349112853 scopus 로고    scopus 로고
    • Interleukin-6 subfamily cytokines and rheumatoid arthritis: Role of antagonists
    • Jazayeri, J. A., Carroll, G. J. & Vernallis, A. B. (2010) Interleukin-6 subfamily cytokines and rheumatoid arthritis: role of antagonists. International Immunopharmacology 10, 1-8.
    • (2010) International Immunopharmacology , vol.10 , pp. 1-8
    • Jazayeri, J.A.1    Carroll, G.J.2    Vernallis, A.B.3
  • 33
    • 0038746758 scopus 로고    scopus 로고
    • Abandoned therapies and unpublished trials in rheumatoid arthritis
    • Keystone, E. C. (2003) Abandoned therapies and unpublished trials in rheumatoid arthritis. Current Opinion in Rheumatology 15, 253-258.
    • (2003) Current Opinion in Rheumatology , vol.15 , pp. 253-258
    • Keystone, E.C.1
  • 37
    • 77956297639 scopus 로고    scopus 로고
    • Psoriasis: Is ustekinumab superior to etanercept for psoriasis?
    • Kuhn, A. & Luger, T. A. (2010) Psoriasis: is ustekinumab superior to etanercept for psoriasis? Nature Reviews Rheumatology 6, 500-501.
    • (2010) Nature Reviews Rheumatology , vol.6 , pp. 500-501
    • Kuhn, A.1    Luger, T.A.2
  • 40
    • 75549087056 scopus 로고    scopus 로고
    • Disease-associated functions of IL-33: The new kid in the IL-1 family
    • Liew, F. Y., Pitman, N. I. & McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology 10, 103-110.
    • (2010) Nature Reviews Immunology , vol.10 , pp. 103-110
    • Liew, F.Y.1    Pitman, N.I.2    McInnes, I.B.3
  • 41
    • 13444256307 scopus 로고    scopus 로고
    • The role of T-cell interleukin-17 in conducting destructive arthritis: Lessons from animal models
    • Lubberts, E., Koenders, M. I. & van den Berg, W. B. (2005) The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Research and Therapy 7, 29-37.
    • (2005) Arthritis Research and Therapy , vol.7 , pp. 29-37
    • Lubberts, E.1    Koenders, M.I.2    Van Den Berg, W.B.3
  • 42
    • 69949189640 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy and periodontal parameters in patients with rheumatoid arthritis
    • Mayer, Y., Balbir-Gurman, A. & Machtei, E. E. (2009) Anti-tumor necrosis factor-alpha therapy and periodontal parameters in patients with rheumatoid arthritis. Journal of Periodontology 80, 1414-1420.
    • (2009) Journal of Periodontology , vol.80 , pp. 1414-1420
    • Mayer, Y.1    Balbir-Gurman, A.2    Machtei, E.E.3
  • 44
    • 0034469236 scopus 로고    scopus 로고
    • Cell-cell interactions in synovitis. Interactions between T lymphocytes and synovial cells
    • McInnes, I. B., Leung, B. P. & Liew, F. Y. (2000) Cell-cell interactions in synovitis. Interactions between T lymphocytes and synovial cells. Arthritis & Research 2, 374-378.
    • (2000) Arthritis & Research , vol.2 , pp. 374-378
    • McInnes, I.B.1    Leung, B.P.2    Liew, F.Y.3
  • 45
    • 0031042456 scopus 로고    scopus 로고
    • Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis
    • DOI 10.1038/nm0297-189
    • McInnes, I. B., Leung, B. P., Sturrock, R. D., Field, M. & Liew, F. Y. (1997) Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Natural Medicines 3, 189-195. (Pubitemid 27064704)
    • (1997) Nature Medicine , vol.3 , Issue.2 , pp. 189-195
    • Mcinnes, I.B.1    Leung, B.P.2    Sturrock, R.D.3    Field, M.4    Liew, F.Y.5
  • 46
    • 34249720998 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of rheumatoid arthritis
    • DOI 10.1038/nri2094, PII NRI2094
    • McInnes, I. B. & Schett, G. (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology 7, 429-442. (Pubitemid 46834849)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.6 , pp. 429-442
    • McInnes, I.B.1    Schett, G.2
  • 47
    • 69249222895 scopus 로고    scopus 로고
    • Role for TNF in atherosclerosis? Lessons from autoimmune disease
    • McKellar, G. E., McCarey, D. W., Sattar, N. & McInnes, I. B. (2009) Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nat Rev Cardiol 6, 410-417.
    • (2009) Nat Rev Cardiol , vol.6 , pp. 410-417
    • McKellar, G.E.1    McCarey, D.W.2    Sattar, N.3    McInnes, I.B.4
  • 49
    • 0019449852 scopus 로고
    • Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis
    • Mohr, W., Westerhellweg, H. & Wessinghage, D. (1981) Polymorphonuclear granulocytes in rheumatic tissue destruction. III. an electron microscopic study of PMNs at the pannus-cartilage junction in rheumatoid arthritis. Annals of the Rheumatic Diseases 40, 396-399.
    • (1981) Annals of the Rheumatic Diseases , vol.40 , pp. 396-399
    • Mohr, W.1    Westerhellweg, H.2    Wessinghage, D.3
  • 50
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • DOI 10.1073/pnas.1035999100
    • Nakae, S., Saijo, S., Horai, R., Sudo, K., Mori, S. & Iwakura, Y. (2003) IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proceedings of the National Academy of Sciences of the United States of America 100, 5986-5990. (Pubitemid 36576918)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.10 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3    Sudo, K.4    Mori, S.5    Iwakura, Y.6
  • 51
    • 36749070996 scopus 로고    scopus 로고
    • Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor alpha agents
    • DOI 10.1002/ibd.20225
    • Nesbitt, A., Fossati, G., Bergin, M., Stephens, P., Stephens, S., Foulkes, R., Brown, D., Robinson, M. & Bourne, T. (2007) Mechanism of action of certolizumab pegol (CDP870): in vitro comparison with other anti-tumor necrosis factor alpha agents. Inflammatory Bowel Diseases 13, 1323-1332. (Pubitemid 350206841)
    • (2007) Inflammatory Bowel Diseases , vol.13 , Issue.11 , pp. 1323-1332
    • Nesbitt, A.1    Fossati, G.2    Bergin, M.3    Stephens, P.4    Stephens, S.5    Foulkes, R.6    Brown, D.7    Robinson, M.8    Bourne, T.9
  • 52
    • 0036483172 scopus 로고    scopus 로고
    • Clinical, radiographic and biochemical assessment of IL-1/TNF-α antagonist inhibition of bone loss in experimental periodontitis
    • DOI 10.1034/j.1600-051x.2002.290208.x
    • Oates, T. W., Graves, D. T. & Cochran, D. L. (2002) Clinical, radiographic and biochemical assessment of IL-1/TNF-α antagonist inhibition of bone loss in experimental periodontitis. Journal of Clinical Periodontology 29, 137-143. (Pubitemid 41697746)
    • (2002) Journal of Clinical Periodontology , vol.29 , Issue.2 , pp. 137-143
    • Oates, T.W.1    Graves, D.T.2    Cochran, D.L.3
  • 53
    • 63849271922 scopus 로고    scopus 로고
    • Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors
    • Ortiz, P., Bissada, N. F., Palomo, L., Han, Y. W., Al- Zahrani, M. S., Panneerselvam, A. & Askari, A. (2009) Periodontal therapy reduces the severity of active rheumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors. Journal of Periodontology 80, 535-540.
    • (2009) Journal of Periodontology , vol.80 , pp. 535-540
    • Ortiz, P.1    Bissada, N.F.2    Palomo, L.3    Han, Y.W.4    Al-Zahrani, M.S.5    Panneerselvam, A.6    Askari, A.7
  • 54
    • 51249097741 scopus 로고    scopus 로고
    • Anti-TNF-alpha immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis
    • Pers, J. O., Saraux, A., Pierre, R. & Youinou, P. (2008) Anti-TNF-alpha immunotherapy is associated with increased gingival inflammation without clinical attachment loss in subjects with rheumatoid arthritis. Journal of Periodontology 79, 1645-1651.
    • (2008) Journal of Periodontology , vol.79 , pp. 1645-1651
    • Pers, J.O.1    Saraux, A.2    Pierre, R.3    Youinou, P.4
  • 57
    • 1442327436 scopus 로고    scopus 로고
    • Periodontal host modulation with antiproteinase, anti-inflammatory, and bone-sparing agents. A systematic review
    • Reddy, M. S., Geurs, N. C. & Gunsolley, J. C. (2003) Periodontal host modulation with antiproteinase, anti-inflammatory, and bone-sparing agents. A systematic review. Annals of Periodontology 8, 12-37.
    • (2003) Annals of Periodontology , vol.8 , pp. 12-37
    • Reddy, M.S.1    Geurs, N.C.2    Gunsolley, J.C.3
  • 59
    • 0036093570 scopus 로고    scopus 로고
    • Biologic therapy of inflammatory bowel disease
    • Sandborn, W. J. & Targan, S. R. (2002) Biologic therapy of inflammatory bowel disease. Gastroenterology 122, 1592-1608. (Pubitemid 34533555)
    • (2002) Gastroenterology , vol.122 , Issue.6 , pp. 1592-1608
    • Sandborn, W.J.1    Targan, S.R.2
  • 61
    • 41549158609 scopus 로고    scopus 로고
    • Cytokines as Therapeutic Targets: Advances and Limitations
    • DOI 10.1016/j.immuni.2008.03.005, PII S1074761308001209
    • Scheinecker, C., Redlich, K. & Smolen, J. S. (2008) Cytokines as therapeutic targets: advances and limitations. Immunity 28, 440-444. (Pubitemid 351467046)
    • (2008) Immunity , vol.28 , Issue.4 , pp. 440-444
    • Scheinecker, C.1    Redlich, K.2    Smolen, J.S.3
  • 63
    • 35648988128 scopus 로고    scopus 로고
    • New therapies for treatment of rheumatoid arthritis
    • DOI 10.1016/S0140-6736(07)60784-3, PII S0140673607607843
    • Smolen, J. S., Aletaha, D., Koeller, M., Weisman, M. H. & Emery, P. (2007) New therapies for treatment of rheumatoid arthritis. Lancet 370, 1861-1874. (Pubitemid 350180008)
    • (2007) Lancet , vol.370 , Issue.9602 , pp. 1861-1874
    • Smolen, J.S.1    Aletaha, D.2    Koeller, M.3    Weisman, M.H.4    Emery, P.5
  • 64
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
    • DOI 10.1016/S0140-6736(08)60453-5, PII S0140673608604535
    • Smolen, J. S., Beaulieu, A., Rubbert-Roth, A., Ramos- Remus, C., Rovensky, J., Alecock, E., Woodworth, T. & Alten, R. (2008) Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double- blind, placebo-controlled, randomised trial. The Lancet 371, 987-997. (Pubitemid 351392039)
    • (2008) The Lancet , vol.371 , Issue.9617 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3    Ramos-Remus, C.4    Rovensky, J.5    Alecock, E.6    Woodworth, T.7    Alten, R.8
  • 66
    • 33746687953 scopus 로고    scopus 로고
    • Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis
    • Tak, P., Bacchi, M. & Bertolino, M. (2006) Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis. European Journal of Drug Metabolism and Pharmacokinetics 31, 109-116. (Pubitemid 44166289)
    • (2006) European Journal of Drug Metabolism and Pharmacokinetics , vol.31 , Issue.2 , pp. 109-116
    • Tak, P.P.1    Bacchi, M.2    Bertolino, M.3    Desson, A.4
  • 68
    • 77955445597 scopus 로고    scopus 로고
    • Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition
    • Toh, M. L., Kawashima, M., Hot, A. & Miossec, P. (2010) Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition. Annals of the Rheumatic Diseases 69, 1562-1567.
    • (2010) Annals of the Rheumatic Diseases , vol.69 , pp. 1562-1567
    • Toh, M.L.1    Kawashima, M.2    Hot, A.3    Miossec, P.4
  • 69
    • 70349968220 scopus 로고    scopus 로고
    • IL-17 as a future therapeutic target for rheumatoid arthritis
    • van den Berg, W. B. & Miossec, P. (2009) IL-17 as a future therapeutic target for rheumatoid arthritis. Nature Reviews Rheumatology 5, 549-553.
    • (2009) Nature Reviews Rheumatology , vol.5 , pp. 549-553
    • Van Den Berg, W.B.1    Miossec, P.2
  • 70
    • 18144362054 scopus 로고    scopus 로고
    • Understanding the genetic contribution to rheumatoid arthritis
    • DOI 10.1097/01.bor.0000160780.13012.be
    • van der Helm-van Mil, A. H., Wesoly, J. Z. & Huizinga, T. W. (2005) Understanding the genetic contribution to rheumatoid arthritis. Current Opinion in Rheumatology 17, 299-304. (Pubitemid 40616576)
    • (2005) Current Opinion in Rheumatology , vol.17 , Issue.3 , pp. 299-304
    • Van Der Helm-van Mil, A.H.M.1    Wesoly, J.Z.2    Huizinga, T.W.J.3
  • 71
    • 34548555687 scopus 로고    scopus 로고
    • Control of inflammation and periodontitis
    • Van Dyke, T. E. (2007) Control of inflammation and periodontitis. Periodontology 2000 45, 158-166.
    • (2007) Periodontology 2000 , vol.45 , pp. 158-166
    • Van Dyke, T.E.1
  • 73
    • 72249087183 scopus 로고    scopus 로고
    • Cytokine responses against periodontal infection: Protective and destructive roles
    • Yen-Chun, G. L., Ulf, H. L. & Yen-Tung, A. T. (2010) Cytokine responses against periodontal infection: protective and destructive roles. Periodontology 2000 52, 163-206.
    • (2010) Periodontology 2000 , vol.52 , pp. 163-206
    • Yen-Chun, G.L.1    Ulf, H.L.2    Yen-Tung, A.T.3
  • 74
    • 34147126728 scopus 로고    scopus 로고
    • An essential role for IL-17 in preventing pathogen-initiated bone destruction: Recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals
    • DOI 10.1182/blood-2005-09-010116
    • Yu, J. J., Ruddy, M. J., Wong, G. C., Sfintescu, C., Baker, P. J., Smith, J. B., Evans, R. T. & Gaffen, S. L. (2007) An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL- 17 receptor-dependent signals. Blood 109, 3794-3802. (Pubitemid 46641730)
    • (2007) Blood , vol.109 , Issue.9 , pp. 3794-3802
    • Yu, J.J.1    Ruddy, M.J.2    Wong, G.C.3    Sfintescu, C.4    Baker, P.J.5    Smith, J.B.6    Evans, R.T.7    Gaffen, S.L.8


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