Periodontal therapy reduces the seveity of active reeumatoid arthritis in patients treated with or without tumor necrosis factor inhibitors

Journal of Periodontology

Volumn 80, Issue 4, 2009, Pages 535-540

  Ortiz, P ^a   Bissada, N F ^a   Palomo, L ^a   Han, Y W ^a   Al Zahrani, M S ^b   Panneerselvam, A ^a   Askari, A ^c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Periodontitis; Rheumatoid arthritis; Therapy; Tumor necrosis factor alpha

Indexed keywords

ANTIRHEUMATIC AGENT; RHEUMATOID FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BLOOD; CHRONIC PERIODONTITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ANTAGONISM; FEMALE; HOSPITALIZATION; HUMAN; MALE; MIDDLE AGED; PERIODONTICS; PREVENTIVE DENTISTRY; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; STATISTICAL MODEL; TOOTH PLAQUE;

ADULT; AGED; AGED, 80 AND OVER; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CHRONIC PERIODONTITIS; DENTAL PLAQUE INDEX; DENTAL SCALING; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; PERIODONTAL INDEX; RHEUMATOID FACTOR; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA;

EID: 63849271922     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.080447     Document Type: Article

References (34)

1. Grassi W, De Angelis R, Lamanna G, Cervini C, The clinical features of rheumatoid arthritis. Eur J Radiol 1998;27:S18-S24,
2. Mereado FB, Marshall RI, Bartold PM. Inter-relationships between rheumatoid arthritis and periodontal disease. A review. J Clin Periodontol 2003;30:761-772.
3. Falcini F, Cimaz R. Juvenile rheumatoid arthritis. Curr Opin Rheumaiol 2000;12:415-419.
4. Kjeldsen M, Holmstrup P, Bendtzen K. Marginal periodontitis and cytokines: A review of the literature. J Periodontol 1993;64:1013-1022.
5. Birkedal-Hansen H, Moore WGI, Bodden MK, Windsor LJ, DeCarlos A, Engler JA. Matrix metalloproteinases: A review. Crit Reυ Oral Biol Med 1993;4:197-250.
6. Bendtzen K. Cytokines and natural regulators of cytokines. Immunol Lett 1994;43:111-123.
7. Havemose-Poulsen A, Holmstrup P. Factors affecting IL-1-mediated collagen metabolism by fibroblasts and the pathogenesis of periodontal disease: A review of the literature. Crit Rev Oral Biol Med 1997;8:217-236.
8. Lerner UH. Iniammation-induced bone remodeling in periodontal disease and the influence of post-meno-pausal osteoporosis. J Dent Res 2006:85:596-607.
9. Assume R, Oates T, Cochran D, Amar S, Graves DT. IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. J Immunol 1998;160:403-409.
10. Kässer UR, Gleissner C, Dehne F, Michel A, Willershausen- Zönnchen B, Bolten WW. Risk for periodontal disease in patients with longstanding rheumatoid arthritis. Arthritis Rheum 1997:40:2248-2251.
11. Mereado F, Marshall RI, Klestov AC, Bartold PM. Is there a relationship between rheumatoid arthritis and periodontal disease? J Clin Periodontol 2000;27:267-272.
12. Mereado FB, Marshall RI, Klestov AC, Bartold PM. Relationship between rheumatoid arthritis and periodontitis. J Periodontol 2001 ;72:779-787.
13. Ramamurthy NS, Greenwald RA, Celiker MY, Shi EY. Experimental arthritis in rats induces bïomarkers of periodontitis which are ameliorated by gene therapy with tissue inhibitor of matrix metalloproteinases. J Periodontol 2005:76:229-233.
14. Moen K, Brun JQ, Valen M, et al. Synovial inflammation in active rheumatoid arthritis and psoriatíc arthritis facilitates trapping of a variety of oral bacterial DMAs. Clin Exp Rheumaiol 2006;24:656-663.
15. Ogrendik M, Kokino S, Ozdemir F, Bird PS, Hamlet S. Serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis. MedGenMed 2005;7:2.
16. Ribeiro J, Leao A, Novaes AB. Periodontal infection as a possible severity factor for rheumatoid arthritis. J Clin Periodontol 2005;32:412-416.
17. Al-Katma MK, Bissada NF, Bordeaux JM, Sue J, Askari AD. Control of periodontal infection reduces the severity of active rheumatoid arthritis. J Clin Rheumatoί 2007;13:134-137.
18. Pischon N, Pischon T, Kroger J, et al. Association among rheumatoid arthritis, oral hygiene, and periodontitis. J Periodontol 2008;79:979-986.
19. Toussirot E, Wendling D. The use of TNF-alpha blocking agents in rheumatoid arthritis: An update. Expert Opin Pharmacother 2007;8:2089-2107.
20. Di Paola R, Mazzon E, Muia C, et al. Effects of etanercept, a tumour necrosis factor-alpha antagonist, in an experimental model of periodontitis in rats. Br J Pharmacol 2007;150:286-297.
21. Kiarash O, Bissada N, Arauz-Dutari J, Askari A. Impact of antï-TNF therapy on periodontitis in rheumatoid arthritis patients. J Dent Res 2007; 86(Spec. Issue A): Abstr. 2506. Available at: http://www.dentalresearch. org.
22. Löe H, Sïlness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963:
23. Löe H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38(Suppl): 610-616.
24. Prevoo ML, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight joint counts: Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-48.
25. Ebersole JL, Machen RL, Steffen MJ, Willmann DE. Systemic acute-phase reactants, C-reactïve protein and haptoglobin, in adult periodontitis. Clin Exp Immunol 1997;107:347-352.
26. Loos BG, Craandijk J, Hoek FJ, Wertheim-van Dillen PM, Van der Velden u. Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol 2000;71:1528-1534.
27. Slade GD, Ghezzi EM, Heiss G, Beck JD, Riche E, Offenbacher S. Relationship between periodontal disease and C-reactive protein among adults in the Atherosclerosis Risk in Communities study. Arch ín-lern Med 2003:163:1172-1179.
28. Noack B, Qenco RJ, Trevisan M, Grossi S, Zambon J J, De Nardin E. Periodontal infections contribute to elevated systemic C-reactive protein level. J Periodontol 2001:72:1221-1227.
29. DΆiuto F, Nïbali L, Parker M, Suvan J, Tonetti MS. Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 2005;84:269-273.
30. Simelyte E. Rimpilainen E, Lehtonen L, Zhang X, Toivanen P. Bacterial cell wall-induced arthritis: Chemical composition and tissue distribution of four Lado-bacillus strains. Infect Immun 2000;68:3535-3540.
31. Yun F, Firkova EI, Xun H, Jun-Qi L. Effects of surgical periodontal therapy on serum levels of TNF-alpha in patients with chronic periodontitis. Folia Med (Ploυdiυ) 2007;49:37-40.
32. Wang Y, Yang PS, Qi XM, Ren JM, Ge SH. Change of circulating TNF-alpha in patients with advanced periodontitis before and after periodontal initial therapy (in Chinese). Shanghai Kon Qiang Yi Xue 2003; 12:85-87,
33. Ide M, McPartlin D, Coward PY, Crook M, Lumb P, Wilson RF. Effect of treatment of chronic periodontitis on levels of serum markers of acute-phase inflammatory and vascular responses. J Clin Periodontol 2003; 30:334-340.
34. Yamazaki K, Honda T, Oda T, et al. Effect of periodontal treatment on the C-reactive protein and proinflammatory cytokine levels in Japanese periodontitis patients. J Periodontal Res 2005;40:53-58.