Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation

ACS Chemical Biology

Volumn 6, Issue 2, 2011, Pages 169-175

  Lodi, Alessia ^a,c   Tiziani, Stefano ^a,d   Khanim, Farhat L ^b   Drayson, Mark T ^b   Günther, Ulrich L ^a   Bunce, Christopher M ^b   Viant, Mark R ^b  

^a School of Cancer Sciences   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; INDOMETACIN; PHOSPHOLIPID; TRICARBOXYLIC ACID;

ACUTE GRANULOCYTIC LEUKEMIA; ADAPTATION; ARTICLE; CANCER CELL CULTURE; CELL METABOLISM; CELL SURVIVAL; CITRIC ACID CYCLE; CONTROLLED STUDY; FATTY ACID SYNTHESIS; GLYCOLYSIS; HYPOXIA; IN VIVO STUDY; LEUKEMIA CELL LINE; METABOLITE; MITOCHONDRIAL RESPIRATION; NUCLEAR MAGNETIC RESONANCE; OXIDATIVE STRESS; OXYGEN TENSION; OXYGENATION; PRIORITY JOURNAL; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT;

ANOXIA; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL HYPOXIA; CELL LINE, TUMOR; CITRIC ACID CYCLE; GLYCOLYSIS; HUMANS; INDOMETHACIN; LEUKEMIA, MYELOID, ACUTE; MAGNETIC RESONANCE SPECTROSCOPY; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN; PHOSPHOLIPIDS;

EID: 79951879368     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb900300j     Document Type: Article

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