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Volumn 50, Issue 3, 2011, Pages 173-183

Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines

Author keywords

AHR; Antagonist; Aryl hydrocarbon receptor; Cytokines; IL6

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; BRG1 PROTEIN; COREPRESSOR PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; RECEPTOR BLOCKING AGENT;

EID: 79951826309     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20702     Document Type: Article
Times cited : (56)

References (55)
  • 2
    • 47749107262 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells
    • Kimura A, Naka T, Nohara K, Fujii-Kuriyama Y, Kishimoto T. Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells. Proc Natl Acad Sci USA 2008; 105: 9721-9726.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9721-9726
    • Kimura, A.1    Naka, T.2    Nohara, K.3    Fujii-Kuriyama, Y.4    Kishimoto, T.5
  • 3
    • 66549088712 scopus 로고    scopus 로고
    • Ah receptor represses acute-phase response gene expression without binding to its cognate response element
    • Patel RD, Murray IA, Flaveny CA, Kusnadi A, Perdew GH. Ah receptor represses acute-phase response gene expression without binding to its cognate response element. Lab Invest 2009; 89: 695-707.
    • (2009) Lab Invest , vol.89 , pp. 695-707
    • Patel, R.D.1    Murray, I.A.2    Flaveny, C.A.3    Kusnadi, A.4    Perdew, G.H.5
  • 4
    • 0029918651 scopus 로고    scopus 로고
    • Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling
    • Kharat I, Saatcioglu F. Antiestrogenic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon- and estrogen-mediated signaling. J Biol Chem 1996; 271: 10533-10537.
    • (1996) J Biol Chem , vol.271 , pp. 10533-10537
    • Kharat, I.1    Saatcioglu, F.2
  • 5
    • 70449589645 scopus 로고    scopus 로고
    • The pleiotropy of dioxin toxicity-xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles
    • Furness SG, Whelan F. The pleiotropy of dioxin toxicity-xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles. Pharmacol Ther 2009; 124: 336-353.
    • (2009) Pharmacol Ther , vol.124 , pp. 336-353
    • Furness, S.G.1    Whelan, F.2
  • 6
    • 0034485357 scopus 로고    scopus 로고
    • Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells
    • Safe S, Wormke M, Samudio I. Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells. J Mammary Gland Biol Neoplasia 2000; 5: 295-306.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 295-306
    • Safe, S.1    Wormke, M.2    Samudio, I.3
  • 7
    • 59149104324 scopus 로고    scopus 로고
    • A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family
    • Vogel CF, Matsumura F. A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem Pharmacol 2009; 77: 734-745.
    • (2009) Biochem Pharmacol , vol.77 , pp. 734-745
    • Vogel, C.F.1    Matsumura, F.2
  • 8
    • 67649985989 scopus 로고    scopus 로고
    • Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor
    • Wang SH, Liang CT, Liu YW, et al. Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor. Toxicology 2009; 262: 87-97.
    • (2009) Toxicology , vol.262 , pp. 87-97
    • Wang, S.H.1    Liang, C.T.2    Liu, Y.W.3
  • 9
    • 69449101827 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands
    • Kawajiri K, Kobayashi Y, Ohtake F, et al. Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci USA 2009; 106: 13481-13486.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13481-13486
    • Kawajiri, K.1    Kobayashi, Y.2    Ohtake, F.3
  • 10
    • 45549093658 scopus 로고    scopus 로고
    • Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells
    • Hollingshead BD, Beischlag TV, DiNatale BC, Ramadoss P, Perdew GH. Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells. Cancer Res 2008; 68: 3609-3617.
    • (2008) Cancer Res , vol.68 , pp. 3609-3617
    • Hollingshead, B.D.1    Beischlag, T.V.2    DiNatale, B.C.3    Ramadoss, P.4    Perdew, G.H.5
  • 11
    • 77955284187 scopus 로고    scopus 로고
    • Mechanistic insights into the events that lead to synergistic induction of IL6 transcription upon activation of the Ah receptor and inflammatory signaling
    • DiNatale BC, Schroeder JC, Francey LJ, Kusnadi A, Perdew GH. Mechanistic insights into the events that lead to synergistic induction of IL6 transcription upon activation of the Ah receptor and inflammatory signaling. J Biol Chem 2010; 285: 24388-24397.
    • (2010) J Biol Chem , vol.285 , pp. 24388-24397
    • DiNatale, B.C.1    Schroeder, J.C.2    Francey, L.J.3    Kusnadi, A.4    Perdew, G.H.5
  • 12
    • 34247849312 scopus 로고    scopus 로고
    • The antiapoptotic effect of IL-6 autocrine loop in a cellular model of advanced prostate cancer is mediated by Mcl-1
    • Cavarretta IT, Neuwirt H, Untergasser G, et al. The antiapoptotic effect of IL-6 autocrine loop in a cellular model of advanced prostate cancer is mediated by Mcl-1. Oncogene 2007; 26: 2822-2832.
    • (2007) Oncogene , vol.26 , pp. 2822-2832
    • Cavarretta, I.T.1    Neuwirt, H.2    Untergasser, G.3
  • 13
    • 0035893768 scopus 로고    scopus 로고
    • Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells
    • Conze D, Weiss L, Regen PS, et al. Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells. Cancer Res 2001; 61: 8851-8858.
    • (2001) Cancer Res , vol.61 , pp. 8851-8858
    • Conze, D.1    Weiss, L.2    Regen, P.S.3
  • 15
    • 0035133050 scopus 로고    scopus 로고
    • Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells
    • Badache A, Hynes NE. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells. Cancer Res 2001; 61: 383-391.
    • (2001) Cancer Res , vol.61 , pp. 383-391
    • Badache, A.1    Hynes, N.E.2
  • 17
    • 36849039660 scopus 로고    scopus 로고
    • IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
    • Sansone P, Storci G, Tavolari S, et al. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland. J Clin Invest 2007; 117: 3988-4002.
    • (2007) J Clin Invest , vol.117 , pp. 3988-4002
    • Sansone, P.1    Storci, G.2    Tavolari, S.3
  • 18
    • 0033017066 scopus 로고    scopus 로고
    • Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer
    • Chen Z, Malhotra PS, Thomas GR, et al. Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer. Clin Cancer Res 1999; 5: 1369-1379.
    • (1999) Clin Cancer Res , vol.5 , pp. 1369-1379
    • Chen, Z.1    Malhotra, P.S.2    Thomas, G.R.3
  • 19
    • 30844463464 scopus 로고    scopus 로고
    • Secretion of tumor-promoting and immune suppressive cytokines by cell lines of head and neck squamous cell carcinoma
    • Pries R, Thiel A, Brocks C, Wollenberg B. Secretion of tumor-promoting and immune suppressive cytokines by cell lines of head and neck squamous cell carcinoma. In Vivo 2006; 20: 45-48.
    • (2006) In Vivo , vol.20 , pp. 45-48
    • Pries, R.1    Thiel, A.2    Brocks, C.3    Wollenberg, B.4
  • 20
    • 0032527621 scopus 로고    scopus 로고
    • Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens
    • Woods KV, El-Naggar A, Clayman GL, Grimm EA. Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens. Cancer Res 1998; 58: 3132-3141.
    • (1998) Cancer Res , vol.58 , pp. 3132-3141
    • Woods, K.V.1    El-Naggar, A.2    Clayman, G.L.3    Grimm, E.A.4
  • 21
    • 50249099346 scopus 로고    scopus 로고
    • Interleukin-6 predicts recurrence and survival among head and neck cancer patients
    • Duffy SA, Taylor JM, Terrell JE, et al. Interleukin-6 predicts recurrence and survival among head and neck cancer patients. Cancer 2008; 113: 750-757.
    • (2008) Cancer , vol.113 , pp. 750-757
    • Duffy, S.A.1    Taylor, J.M.2    Terrell, J.E.3
  • 22
    • 57149099179 scopus 로고    scopus 로고
    • Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF
    • Tong M, Lloyd B, Pei P, Mallery SR. Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF. J Cell Biochem 2008; 105: 1202-1210.
    • (2008) J Cell Biochem , vol.105 , pp. 1202-1210
    • Tong, M.1    Lloyd, B.2    Pei, P.3    Mallery, S.R.4
  • 23
    • 0036791156 scopus 로고    scopus 로고
    • Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa
    • Rinaldi AL, Morse MA, Fields HW, et al. Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7, 8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa. Cancer Res 2002; 62: 5451-5456.
    • (2002) Cancer Res , vol.62 , pp. 5451-5456
    • Rinaldi, A.L.1    Morse, M.A.2    Fields, H.W.3
  • 24
    • 0028566272 scopus 로고
    • MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma
    • Yeudall WA, Crawford RY, Ensley JF, Robbins KC. MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma. Carcinogenesis 1994; 15: 2683-2686.
    • (1994) Carcinogenesis , vol.15 , pp. 2683-2686
    • Yeudall, W.A.1    Crawford, R.Y.2    Ensley, J.F.3    Robbins, K.C.4
  • 25
    • 34248148710 scopus 로고    scopus 로고
    • Oestrogen receptor negative breast cancers exhibit high cytokine content
    • Chavey C, Bibeau F, Gourgou-Bourgade S, et al. Oestrogen receptor negative breast cancers exhibit high cytokine content. Breast Cancer Res 2007; 9: R15.
    • (2007) Breast Cancer Res , vol.9
    • Chavey, C.1    Bibeau, F.2    Gourgou-Bourgade, S.3
  • 26
    • 73949154910 scopus 로고    scopus 로고
    • Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone
    • Murray IA, Flaveny CA, DiNatale BC, et al. Antagonism of aryl hydrocarbon receptor signaling by 6, 2', 4'-trimethoxyflavone. J Pharmacol Exp Ther 2010; 332: 135-144.
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 135-144
    • Murray, I.A.1    Flaveny, C.A.2    DiNatale, B.C.3
  • 27
    • 0037023766 scopus 로고    scopus 로고
    • Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex
    • Wang S, Hankinson O. Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex. J Biol Chem 2002; 277: 11821-11827.
    • (2002) J Biol Chem , vol.277 , pp. 11821-11827
    • Wang, S.1    Hankinson, O.2
  • 28
    • 58049209785 scopus 로고    scopus 로고
    • Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells
    • Taylor RT, Wang F, Hsu EL, Hankinson O. Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells. Toxicol Sci 2009; 107: 1-8.
    • (2009) Toxicol Sci , vol.107 , pp. 1-8
    • Taylor, R.T.1    Wang, F.2    Hsu, E.L.3    Hankinson, O.4
  • 30
    • 26844579129 scopus 로고    scopus 로고
    • Apical role for BRG1 in cytokine-induced promoter assembly
    • Ni Z, Karaskov E, Yu T, et al. Apical role for BRG1 in cytokine-induced promoter assembly. Proc Natl Acad Sci USA 2005; 102: 14611-14616.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14611-14616
    • Ni, Z.1    Karaskov, E.2    Yu, T.3
  • 31
    • 66549106623 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor: A perspective on potential roles in the immune system
    • Stevens EA, Mezrich JD, Bradfield CA. The aryl hydrocarbon receptor: A perspective on potential roles in the immune system. Immunology 2009; 127: 299-311.
    • (2009) Immunology , vol.127 , pp. 299-311
    • Stevens, E.A.1    Mezrich, J.D.2    Bradfield, C.A.3
  • 32
    • 0037369909 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages
    • van Grevenynghe J, Rion S, Le Ferrec E, et al. Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages. J Immunol 2003; 170: 2374-2381.
    • (2003) J Immunol , vol.170 , pp. 2374-2381
    • van Grevenynghe, J.1    Rion, S.2    Le Ferrec, E.3
  • 33
    • 77955362056 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth
    • Dietrich C, Kaina B. The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth. Carcinogenesis 2010; 8: 1319-1328.
    • (2010) Carcinogenesis , vol.8 , pp. 1319-1328
    • Dietrich, C.1    Kaina, B.2
  • 34
    • 77649215840 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer
    • Ishida M, Mikami S, Kikuchi E, et al. Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer. Carcinogenesis 2010; 31: 287-295.
    • (2010) Carcinogenesis , vol.31 , pp. 287-295
    • Ishida, M.1    Mikami, S.2    Kikuchi, E.3
  • 35
    • 49449091484 scopus 로고    scopus 로고
    • Leukotriene A4 metabolites are endogenous ligands for the Ah receptor
    • Chiaro CR, Morales JL, Prabhu KS, Perdew GH. Leukotriene A4 metabolites are endogenous ligands for the Ah receptor. Biochemistry 2008; 47: 8445-8455.
    • (2008) Biochemistry , vol.47 , pp. 8445-8455
    • Chiaro, C.R.1    Morales, J.L.2    Prabhu, K.S.3    Perdew, G.H.4
  • 36
    • 57349122123 scopus 로고    scopus 로고
    • 12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor
    • Chiaro CR, Patel RD, Perdew GH. 12(R)-Hydroxy-5(Z), 8(Z), 10(E), 14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor. Mol Pharmacol 2008; 74: 1649-1656.
    • (2008) Mol Pharmacol , vol.74 , pp. 1649-1656
    • Chiaro, C.R.1    Patel, R.D.2    Perdew, G.H.3
  • 37
    • 79551688725 scopus 로고    scopus 로고
    • Kynurenic acid is a potent endogenous Ah receptor ligand that synergistically induces interleukin 6 in the presence of inflammatory signaling
    • DiNatale BC, Murray IA, Schroeder JC, et al. Kynurenic acid is a potent endogenous Ah receptor ligand that synergistically induces interleukin 6 in the presence of inflammatory signaling. Toxicol Sci 2010; 115: 89-97.
    • (2010) Toxicol Sci , vol.115 , pp. 89-97
    • DiNatale, B.C.1    Murray, I.A.2    Schroeder, J.C.3
  • 38
    • 75349102699 scopus 로고    scopus 로고
    • The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor
    • Schroeder JC, DiNatale BC, Murray IA, et al. The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry 2010; 49: 393-400.
    • (2010) Biochemistry , vol.49 , pp. 393-400
    • Schroeder, J.C.1    DiNatale, B.C.2    Murray, I.A.3
  • 39
    • 0038581774 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system
    • Sriuranpong V, Park JI, Amornphimoltham P, Patel V, Nelkin BD, Gutkind JS. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. Cancer Res 2003; 63: 2948-2956.
    • (2003) Cancer Res , vol.63 , pp. 2948-2956
    • Sriuranpong, V.1    Park, J.I.2    Amornphimoltham, P.3    Patel, V.4    Nelkin, B.D.5    Gutkind, J.S.6
  • 40
    • 33747470228 scopus 로고    scopus 로고
    • Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane)
    • Chakravarti N, Myers JN, Aggarwal BB. Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane). Int J Cancer 2006; 119: 1268-1275.
    • (2006) Int J Cancer , vol.119 , pp. 1268-1275
    • Chakravarti, N.1    Myers, J.N.2    Aggarwal, B.B.3
  • 41
    • 70849126744 scopus 로고    scopus 로고
    • Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
    • Leeman-Neill RJ, Wheeler SE, Singh SV, et al. Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3. Carcinogenesis 2009; 30: 1848-1856.
    • (2009) Carcinogenesis , vol.30 , pp. 1848-1856
    • Leeman-Neill, R.J.1    Wheeler, S.E.2    Singh, S.V.3
  • 42
    • 77349109465 scopus 로고    scopus 로고
    • Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma
    • Gu F, Ma Y, Zhang Z, et al. Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma. Oncol Rep 2010; 23: 671-676.
    • (2010) Oncol Rep , vol.23 , pp. 671-676
    • Gu, F.1    Ma, Y.2    Zhang, Z.3
  • 43
    • 77949445285 scopus 로고    scopus 로고
    • Antitumor effects of lapatinib (GW572016), a dual inhibitor of EGFR and HER-2, in combination with cisplatin or paclitaxel on head and neck squamous cell carcinoma
    • Kondo N, Tsukuda M, Ishiguro Y, et al. Antitumor effects of lapatinib (GW572016), a dual inhibitor of EGFR and HER-2, in combination with cisplatin or paclitaxel on head and neck squamous cell carcinoma. Oncol Rep 2010; 23: 957-963.
    • (2010) Oncol Rep , vol.23 , pp. 957-963
    • Kondo, N.1    Tsukuda, M.2    Ishiguro, Y.3
  • 44
    • 0036751172 scopus 로고    scopus 로고
    • Treatment of locally advanced head and neck cancer: Historical and critical review
    • Al-Sarraf M. Treatment of locally advanced head and neck cancer: Historical and critical review. Cancer Control 2002; 9: 387-399.
    • (2002) Cancer Control , vol.9 , pp. 387-399
    • Al-Sarraf, M.1
  • 45
    • 70350066363 scopus 로고    scopus 로고
    • Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity
    • Bui LC, Tomkiewicz C, Chevallier A, et al. Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity. Oncogene 2009; 28: 3642-3651.
    • (2009) Oncogene , vol.28 , pp. 3642-3651
    • Bui, L.C.1    Tomkiewicz, C.2    Chevallier, A.3
  • 46
    • 64549140740 scopus 로고    scopus 로고
    • Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells
    • Hashimoto Y, Loftis DW, Adams JC. Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells. PLoS One 2009; 4: e5130.
    • (2009) PLoS One , vol.4
    • Hashimoto, Y.1    Loftis, D.W.2    Adams, J.C.3
  • 47
    • 65249172049 scopus 로고    scopus 로고
    • The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion
    • Carvajal-Gonzalez JM, Mulero-Navarro S, Roman AC, et al. The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. Mol Biol Cell 2009; 20: 1715-1727.
    • (2009) Mol Biol Cell , vol.20 , pp. 1715-1727
    • Carvajal-Gonzalez, J.M.1    Mulero-Navarro, S.2    Roman, A.C.3
  • 48
    • 23944468777 scopus 로고    scopus 로고
    • Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output
    • Miller ME, Holloway AC, Foster WG. Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output. Clin Exp Metastasis 2005; 22: 149-156.
    • (2005) Clin Exp Metastasis , vol.22 , pp. 149-156
    • Miller, M.E.1    Holloway, A.C.2    Foster, W.G.3
  • 49
    • 41649093550 scopus 로고    scopus 로고
    • TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A
    • Weiss C, Faust D, Schreck I, et al. TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A. Oncogene 2008; 27: 2198-2207.
    • (2008) Oncogene , vol.27 , pp. 2198-2207
    • Weiss, C.1    Faust, D.2    Schreck, I.3
  • 50
    • 65649152559 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9
    • Peng TL, Chen J, Mao W, Song X, Chen MH. Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9. BMC Cell Biol 2009; 10: 27.
    • (2009) BMC Cell Biol , vol.10 , pp. 27
    • Peng, T.L.1    Chen, J.2    Mao, W.3    Song, X.4    Chen, M.H.5
  • 51
    • 61449138610 scopus 로고    scopus 로고
    • The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice
    • Fritz WA, Lin TM, Safe S, Moore RW, Peterson RE. The selective aryl hydrocarbon receptor modulator 6-methyl-1, 3, 8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice. Biochem Pharmacol 2009; 77: 1151-1160.
    • (2009) Biochem Pharmacol , vol.77 , pp. 1151-1160
    • Fritz, W.A.1    Lin, T.M.2    Safe, S.3    Moore, R.W.4    Peterson, R.E.5
  • 52
    • 72749083607 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy
    • Zhang S, Lei P, Liu X, et al. The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy. Endocr Relat Cancer 2009; 16: 835-844.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 835-844
    • Zhang, S.1    Lei, P.2    Liu, X.3
  • 53
    • 77952376152 scopus 로고    scopus 로고
    • Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties
    • Murray IA, Krishnegowda G, DiNatale BC, et al. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chem Res Toxicol 2010; 23: 955-966.
    • (2010) Chem Res Toxicol , vol.23 , pp. 955-966
    • Murray, I.A.1    Krishnegowda, G.2    DiNatale, B.C.3
  • 54
    • 0027389132 scopus 로고
    • Influence of cigarette smoking on the efficacy of radiation therapy in head and neck cancer
    • Browman GP, Wong G, Hodson I, et al. Influence of cigarette smoking on the efficacy of radiation therapy in head and neck cancer. N Engl J Med 1993; 328: 159-163.
    • (1993) N Engl J Med , vol.328 , pp. 159-163
    • Browman, G.P.1    Wong, G.2    Hodson, I.3
  • 55
    • 70349272869 scopus 로고    scopus 로고
    • Complications of radiotherapy in laryngopharyngeal cancer: Effects of a prospective smoking cessation program
    • Zevallos JP, Mallen MJ, Lam CY, et al. Complications of radiotherapy in laryngopharyngeal cancer: Effects of a prospective smoking cessation program. Cancer 2009; 115: 4636-4644.
    • (2009) Cancer , vol.115 , pp. 4636-4644
    • Zevallos, J.P.1    Mallen, M.J.2    Lam, C.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.