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Volumn 47, Issue 32, 2008, Pages 8445-8455

Leukotriene A4 metabolites are endogenous ligands for the Ah receptor

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC COMPOUNDS; CHLORINE COMPOUNDS; HYDROCARBONS; ORGANIC COMPOUNDS;

EID: 49449091484     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800712f     Document Type: Article
Times cited : (52)

References (50)
  • 1
    • 0034116376 scopus 로고    scopus 로고
    • The PAS superfamily: Sensors of environmental and developmental signals
    • Gu, Y. Z., Hogenesch, J. B., and Bradfield, C. A. (2000) The PAS superfamily: Sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40, 519-561.
    • (2000) Annu. Rev. Pharmacol. Toxicol , vol.40 , pp. 519-561
    • Gu, Y.Z.1    Hogenesch, J.B.2    Bradfield, C.A.3
  • 2
    • 0032788143 scopus 로고    scopus 로고
    • Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt
    • Lees, M. J., and Whitelaw, M. L. (1999) Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt. Mol. Cell. Biol. 19, 5811-5822.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 5811-5822
    • Lees, M.J.1    Whitelaw, M.L.2
  • 3
    • 0030888748 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated signal transduction
    • Rowlands, J. C., and Gustafsson, J. A. (1997) Aryl hydrocarbon receptor-mediated signal transduction. Crit. Rev. Toxicol. 27, 109-134.
    • (1997) Crit. Rev. Toxicol , vol.27 , pp. 109-134
    • Rowlands, J.C.1    Gustafsson, J.A.2
  • 4
    • 0024210678 scopus 로고
    • The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis
    • Denison, M. S., Fisher, J. M., and Whitlock, J. P. (1988) The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. J. Biol. Chem. 263, 17221-17224.
    • (1988) J. Biol. Chem , vol.263 , pp. 17221-17224
    • Denison, M.S.1    Fisher, J.M.2    Whitlock, J.P.3
  • 6
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison, M. S., and Nagy, S. R. (2003) Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43, 309-334.
    • (2003) Annu. Rev. Pharmacol. Toxicol , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 7
    • 2642510760 scopus 로고    scopus 로고
    • Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
    • Nebert, D. W., Dalton, T. P., Okey, A. B., and Gonzalez, F. J. (2004) Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J. Biol. Chem. 279, 23847-23850.
    • (2004) J. Biol. Chem , vol.279 , pp. 23847-23850
    • Nebert, D.W.1    Dalton, T.P.2    Okey, A.B.3    Gonzalez, F.J.4
  • 8
    • 14944374033 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse
    • Lahvis, G. P., Pyzalski, R. W., Glover, E., Pitot, H. C., McElwee, M. K., and Bradfield, C. A. (2005) The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse. Mol. Pharmacol. 67, 714-720.
    • (2005) Mol. Pharmacol , vol.67 , pp. 714-720
    • Lahvis, G.P.1    Pyzalski, R.W.2    Glover, E.3    Pitot, H.C.4    McElwee, M.K.5    Bradfield, C.A.6
  • 10
    • 0344393077 scopus 로고    scopus 로고
    • Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure
    • Lund, A. K., Goens, M. B., Kanagy, N. L., and Walker, M. K. (2003) Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure. Toxicol. Appl. Pharmacol. 193, 177-187.
    • (2003) Toxicol. Appl. Pharmacol , vol.193 , pp. 177-187
    • Lund, A.K.1    Goens, M.B.2    Kanagy, N.L.3    Walker, M.K.4
  • 11
    • 0018710244 scopus 로고
    • Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds
    • Borgeat, P., and Samuelsson, B. (1979) Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. J. Biol. Chem. 254, 7865-7869.
    • (1979) J. Biol. Chem , vol.254 , pp. 7865-7869
    • Borgeat, P.1    Samuelsson, B.2
  • 12
    • 0009582144 scopus 로고
    • Arachidonic acid metabolism in polymorphonuclear leukocytes: Unstable intermediate in formation of dihydroxy acids
    • Borgeat, P., and Samuelsson, B. (1979) Arachidonic acid metabolism in polymorphonuclear leukocytes: Unstable intermediate in formation of dihydroxy acids. Proc. Natl. Acad. Sci. U.S.A. 76, 3213-3217.
    • (1979) Proc. Natl. Acad. Sci. U.S.A , vol.76 , pp. 3213-3217
    • Borgeat, P.1    Samuelsson, B.2
  • 13
    • 21644440188 scopus 로고    scopus 로고
    • Fatty acid binding proteins stabilize leukotriene A4: Competition with arachidonic acid but not other lipoxygenase products
    • Zimmer, J. S., Dyckes, D. F., Bernlohr, D. A., and Murphy, R. C. (2004) Fatty acid binding proteins stabilize leukotriene A4: Competition with arachidonic acid but not other lipoxygenase products. J. Lipid Res. 45, 2138-2144.
    • (2004) J. Lipid Res , vol.45 , pp. 2138-2144
    • Zimmer, J.S.1    Dyckes, D.F.2    Bernlohr, D.A.3    Murphy, R.C.4
  • 14
    • 0001465756 scopus 로고
    • Leukotriene C: A slow-reacting substance from murine mastocytoma cells
    • Murphy, R. C., Hammarstrom, S., and Samuelsson, B. (1979) Leukotriene C: A slow-reacting substance from murine mastocytoma cells. Proc. Natl. Acad. Sci. U.S.A. 76, 4275-4279.
    • (1979) Proc. Natl. Acad. Sci. U.S.A , vol.76 , pp. 4275-4279
    • Murphy, R.C.1    Hammarstrom, S.2    Samuelsson, B.3
  • 15
    • 0019254822 scopus 로고
    • Leukotrienes are potent constrictors of human bronchi
    • Dahlen, S. E., Hedqvist, P., Hammarstrom, S., and Samuelsson, B. (1980) Leukotrienes are potent constrictors of human bronchi. Nature 288, 484-486.
    • (1980) Nature , vol.288 , pp. 484-486
    • Dahlen, S.E.1    Hedqvist, P.2    Hammarstrom, S.3    Samuelsson, B.4
  • 16
    • 0024268004 scopus 로고
    • Purification and characterization of leukotriene A4 epoxide hydrolase from dog lung
    • Manganaro, F., Gaudette, Y., Pombo-Gentile, A., Singh, K., and Rakhit, S. (1988) Purification and characterization of leukotriene A4 epoxide hydrolase from dog lung. Prostaglandins 36, 859-874.
    • (1988) Prostaglandins , vol.36 , pp. 859-874
    • Manganaro, F.1    Gaudette, Y.2    Pombo-Gentile, A.3    Singh, K.4    Rakhit, S.5
  • 17
    • 0024368596 scopus 로고
    • Enzymes involved in the biosynthesis of leukotriene B4
    • Samuelsson, B., and Funk, C. D. (1989) Enzymes involved in the biosynthesis of leukotriene B4. J. Biol. Chem. 264, 19469-19472.
    • (1989) J. Biol. Chem , vol.264 , pp. 19469-19472
    • Samuelsson, B.1    Funk, C.D.2
  • 18
    • 0022931514 scopus 로고
    • Leukotriene A4. Enzymatic conversion into 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid by mouse liver cytosolic epoxide hydrolase
    • Haeggstrom, J., Meijer, J., and Radmark, O. (1986) Leukotriene A4. Enzymatic conversion into 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid by mouse liver cytosolic epoxide hydrolase. J. Biol. Chem. 261, 6332-6337.
    • (1986) J. Biol. Chem , vol.261 , pp. 6332-6337
    • Haeggstrom, J.1    Meijer, J.2    Radmark, O.3
  • 19
    • 0023836686 scopus 로고
    • Enzymatic formation of 5,6-dihydroxy-7,9,11,14- eicosatetraenoic acid: Kinetics of the reaction and stereochemistry of the product
    • Haeggstrom, J., Wetterholm, A., Hamberg, M., Meijer, J., Zipkin, R., and Radmark, O. (1988) Enzymatic formation of 5,6-dihydroxy-7,9,11,14- eicosatetraenoic acid: Kinetics of the reaction and stereochemistry of the product. Biochim. Biophys. Acta 958, 469-476.
    • (1988) Biochim. Biophys. Acta , vol.958 , pp. 469-476
    • Haeggstrom, J.1    Wetterholm, A.2    Hamberg, M.3    Meijer, J.4    Zipkin, R.5    Radmark, O.6
  • 20
    • 0026631715 scopus 로고
    • Conversion of 5,6-dihydroxyeicosatetraenoic acids A novel pathway for lipoxin formation by human platelets
    • Tomhamre, S., Gigou, A., Edenius, C., Lellouche, J.-P., and Lindgren, J. A. (1992) Conversion of 5,6-dihydroxyeicosatetraenoic acids A novel pathway for lipoxin formation by human platelets. FEBS Lett. 304, 78-82.
    • (1992) FEBS Lett , vol.304 , pp. 78-82
    • Tomhamre, S.1    Gigou, A.2    Edenius, C.3    Lellouche, J.-P.4    Lindgren, J.A.5
  • 21
    • 0031958368 scopus 로고    scopus 로고
    • Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction
    • Long, W. P., Pray-Grant, M., Tsai, J. C., and Perdew, G. H. (1998) Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction. Mol. Pharmacol. 53, 691-700.
    • (1998) Mol. Pharmacol , vol.53 , pp. 691-700
    • Long, W.P.1    Pray-Grant, M.2    Tsai, J.C.3    Perdew, G.H.4
  • 22
    • 26844566935 scopus 로고    scopus 로고
    • Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals
    • Garrison, P. M., Tullis, K., Aarts, J. M., Brouwer, A., Giesy, J. P., and Denison, M. S. (1996) Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam. Appl. Toxicol. 30, 194-203.
    • (1996) Fundam. Appl. Toxicol , vol.30 , pp. 194-203
    • Garrison, P.M.1    Tullis, K.2    Aarts, J.M.3    Brouwer, A.4    Giesy, J.P.5    Denison, M.S.6
  • 24
    • 0031972786 scopus 로고    scopus 로고
    • Constitutive activation of the aromatic hydrocarbon receptor
    • Chang, C. Y., and Puga, A. (1998) Constitutive activation of the aromatic hydrocarbon receptor. Mol. Cell. Biol. 18, 525-535.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 525-535
    • Chang, C.Y.1    Puga, A.2
  • 25
    • 35548946775 scopus 로고    scopus 로고
    • Evidence for an Ah receptor-mediated cytochrome P450 autoregulatory pathway
    • Chiaro, C. R., Patel, R. D., Marcus, C. B., and Perdew, G. H. (2007) Evidence for an Ah receptor-mediated cytochrome P450 autoregulatory pathway. Mol. Pharmacol. 72, 1369-1379.
    • (2007) Mol. Pharmacol , vol.72 , pp. 1369-1379
    • Chiaro, C.R.1    Patel, R.D.2    Marcus, C.B.3    Perdew, G.H.4
  • 27
    • 0021025704 scopus 로고
    • The myeloperoxidase-dependent metabolism of leukotrienes C4, D4, and E4 to 6-trans-leukotriene B4 diastereoisomers and the subclass-specific S-diastereoisomeric sulfoxides
    • Lee, C. W., Lewis, R. A., Tauber, A. I., Mehrotra, M., Corey, E. J., and Austen, K. F. (1983) The myeloperoxidase-dependent metabolism of leukotrienes C4, D4, and E4 to 6-trans-leukotriene B4 diastereoisomers and the subclass-specific S-diastereoisomeric sulfoxides. J. Biol. Chem. 258, 15004-15010.
    • (1983) J. Biol. Chem , vol.258 , pp. 15004-15010
    • Lee, C.W.1    Lewis, R.A.2    Tauber, A.I.3    Mehrotra, M.4    Corey, E.J.5    Austen, K.F.6
  • 28
    • 0023115516 scopus 로고
    • Enzymatic conversion of leukotriene B4 to 6-trans-leukotriene B4 by rat kidney homogenates
    • Breuer, O., and Hammarstrom, S. (1987) Enzymatic conversion of leukotriene B4 to 6-trans-leukotriene B4 by rat kidney homogenates. Biochem. Biophys. Res. Commun. 142, 667-673.
    • (1987) Biochem. Biophys. Res. Commun , vol.142 , pp. 667-673
    • Breuer, O.1    Hammarstrom, S.2
  • 29
    • 0018418754 scopus 로고
    • Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid
    • Borgeat, P., and Samuelsson, B. (1979) Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. J. Biol. Chem. 254, 2643-2646.
    • (1979) J. Biol. Chem , vol.254 , pp. 2643-2646
    • Borgeat, P.1    Samuelsson, B.2
  • 30
    • 0023883133 scopus 로고
    • The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes
    • Ueda, N., and Yamamoto, S. (1988) The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes. J. Biol. Chem. 263, 1937-1941.
    • (1988) J. Biol. Chem , vol.263 , pp. 1937-1941
    • Ueda, N.1    Yamamoto, S.2
  • 31
    • 0019837818 scopus 로고
    • Metabolism of leukotriene D by porcine kidney
    • Bemstrom, K., and Hammarstrom, S. (1981) Metabolism of leukotriene D by porcine kidney. J. Biol. Chem. 256, 9579-9582.
    • (1981) J. Biol. Chem , vol.256 , pp. 9579-9582
    • Bemstrom, K.1    Hammarstrom, S.2
  • 34
    • 0035808265 scopus 로고    scopus 로고
    • Intracellular compartmentalization of leukotriene synthesis: Unexpected nuclear secrets
    • Peters-Golden, M., and Brock, T. G. (2001) Intracellular compartmentalization of leukotriene synthesis: Unexpected nuclear secrets. FEBS Lett. 487, 323-326.
    • (2001) FEBS Lett , vol.487 , pp. 323-326
    • Peters-Golden, M.1    Brock, T.G.2
  • 36
    • 23944521767 scopus 로고    scopus 로고
    • The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties
    • Ramadoss, P., and Perdew, G. H. (2005) The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties. Biochemistry 44, 11148-11159.
    • (2005) Biochemistry , vol.44 , pp. 11148-11159
    • Ramadoss, P.1    Perdew, G.H.2
  • 38
    • 0029003424 scopus 로고
    • Production and characterization of monoclonal antibodies directed against the Ah receptor
    • Perdew, G. H., Abbott, B., and Stanker, L. H. (1995) Production and characterization of monoclonal antibodies directed against the Ah receptor. Hybridoma 14, 279-283.
    • (1995) Hybridoma , vol.14 , pp. 279-283
    • Perdew, G.H.1    Abbott, B.2    Stanker, L.H.3
  • 39
    • 0037145026 scopus 로고    scopus 로고
    • Ah receptor and NF-κB interactions: Mechanisms and physiological implications
    • Tian, Y., Rabson, A. B., and Gallo, M. A. (2002) Ah receptor and NF-κB interactions: Mechanisms and physiological implications. Chem.-Biol. Interact. 141, 97-115.
    • (2002) Chem.-Biol. Interact , vol.141 , pp. 97-115
    • Tian, Y.1    Rabson, A.B.2    Gallo, M.A.3
  • 40
    • 0036765531 scopus 로고    scopus 로고
    • 2,3,7,8- Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-α and anti-CD40-induced activation of NF-κB/Rel in dendritic cells: P50 homodimer activation is not affected
    • Ruby, C. E., Leid, M., and Kerkvliet, N. I. (2002) 2,3,7,8- Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis factor-α and anti-CD40-induced activation of NF-κB/Rel in dendritic cells: p50 homodimer activation is not affected. Mol. Pharmacol. 62, 722-728.
    • (2002) Mol. Pharmacol , vol.62 , pp. 722-728
    • Ruby, C.E.1    Leid, M.2    Kerkvliet, N.I.3
  • 41
    • 49449095646 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low molecular weight compound
    • in press
    • Lawrence, B. P., Denison, M. S., Novak, H., Vorderstrasse, B. A., Harrer, N., Neruda, W., Reichel, C., and Woisetschlager, M. (2008) Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low molecular weight compound. Blood . (in press).
    • (2008) Blood
    • Lawrence, B.P.1    Denison, M.S.2    Novak, H.3    Vorderstrasse, B.A.4    Harrer, N.5    Neruda, W.6    Reichel, C.7    Woisetschlager, M.8
  • 42
    • 33644831336 scopus 로고    scopus 로고
    • Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent
    • Machado, F. S., Johndrow, J. E., Esper, L., Dias, A., Bafica, A., Serhan, C. N., and Aliberti, J. (2006) Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent. Nat. Med. 12, 330-334.
    • (2006) Nat. Med , vol.12 , pp. 330-334
    • Machado, F.S.1    Johndrow, J.E.2    Esper, L.3    Dias, A.4    Bafica, A.5    Serhan, C.N.6    Aliberti, J.7
  • 43
    • 9444236827 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells
    • Boverhof, D. R., Tam, E., Hamey, A. S., Crawford, R. B., Kaminski, N. E., and Zacharewski, T. R. (2004) 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells. Mol. Pharmacol. 66, 1662-1670.
    • (2004) Mol. Pharmacol , vol.66 , pp. 1662-1670
    • Boverhof, D.R.1    Tam, E.2    Hamey, A.S.3    Crawford, R.B.4    Kaminski, N.E.5    Zacharewski, T.R.6
  • 46
    • 15844391135 scopus 로고    scopus 로고
    • Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells
    • VanRollins, M., Kaduce, T. L., Fang, X., Knapp, H. R., and Spector, A. A. (1996) Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells. J. Biol. Chem. 271, 14001-14009.
    • (1996) J. Biol. Chem , vol.271 , pp. 14001-14009
    • VanRollins, M.1    Kaduce, T.L.2    Fang, X.3    Knapp, H.R.4    Spector, A.A.5
  • 47
    • 0029157115 scopus 로고
    • Metabolism of 6-transisomers of leukotriene B4 in cultured hepatoma cells and in human polymorphonuclear leukocytes. Identification of a Δ6-reductase metabolic pathway
    • Wheelan, P., and Murphy, R. C. (1995) Metabolism of 6-transisomers of leukotriene B4 in cultured hepatoma cells and in human polymorphonuclear leukocytes. Identification of a Δ6-reductase metabolic pathway. J. Biol. Chem. 270, 19845-19852.
    • (1995) J. Biol. Chem , vol.270 , pp. 19845-19852
    • Wheelan, P.1    Murphy, R.C.2
  • 48
    • 2942600176 scopus 로고    scopus 로고
    • Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism
    • Gouedard, C., Barouki, R., and Morel, Y. (2004) Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism. Mol. Cell. Biol. 24, 5209-5222.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 5209-5222
    • Gouedard, C.1    Barouki, R.2    Morel, Y.3
  • 49
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J. (2000) Atherosclerosis. Nature 407, 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 50
    • 0034612175 scopus 로고    scopus 로고
    • Akiyama, H., Barger, S., Barnum, S., Bradt, B., Bauer, J., Cole, G. M., Cooper, N. R., Eikelenboom, P., Emmerling, M., Fiebich, B. L., Finch, C. E., Frautschy, S., Griffin, W. S., Hampel, H., Hull, M., Landreth, G., Lue, L., Mrak, R., Mackenzie, I. R., McGeer, P. L., O'Banion, M. K., Pachter, J., Pasinetti, G., Plata-Salaman, C., Rogers, J., Rydel, R., Shen, Y., Streit, W., Strohmeyer, R., Tooyoma, I., Van Muiswinkel, F. L., Veerhuis, R., Walker, D., Webster, S., Wegrzyniak, B., Wenk, G., and Wyss-Coray, T. (2000) Inflammation and Alzheimer's disease. Neurobiol. Aging 21, 383-421.
    • Akiyama, H., Barger, S., Barnum, S., Bradt, B., Bauer, J., Cole, G. M., Cooper, N. R., Eikelenboom, P., Emmerling, M., Fiebich, B. L., Finch, C. E., Frautschy, S., Griffin, W. S., Hampel, H., Hull, M., Landreth, G., Lue, L., Mrak, R., Mackenzie, I. R., McGeer, P. L., O'Banion, M. K., Pachter, J., Pasinetti, G., Plata-Salaman, C., Rogers, J., Rydel, R., Shen, Y., Streit, W., Strohmeyer, R., Tooyoma, I., Van Muiswinkel, F. L., Veerhuis, R., Walker, D., Webster, S., Wegrzyniak, B., Wenk, G., and Wyss-Coray, T. (2000) Inflammation and Alzheimer's disease. Neurobiol. Aging 21, 383-421.


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