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Volumn 9, Issue 2, 2011, Pages 188-199

Neopterin: From Forgotten Biomarker to Leading Actor in Cardiovascular Pathophysiology

Author keywords

Atherosclerosis; Cardiovascular disease; Inflammation; Neopterin

Indexed keywords

ATORVASTATIN; BIOLOGICAL MARKER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NEOPTERIN; PRAVASTATIN;

EID: 79951693944     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016111794519372     Document Type: Article
Times cited : (57)

References (144)
  • 1
    • 71549121695 scopus 로고    scopus 로고
    • Treating inflammation in atherosclerotic cardiovascular disease: Emerging therapies
    • Klingenberg R, Hansson GK. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur Heart J 2009; 30: 2838-44.
    • (2009) Eur Heart J , vol.30 , pp. 2838-2844
    • Klingenberg, R.1    Hansson, G.K.2
  • 2
    • 71949107774 scopus 로고    scopus 로고
    • Innate immune signals in atherosclerosis
    • Lundberg AM, Hansson GK. Innate immune signals in atherosclerosis. Clin Immunol 2010; 134: 5-24.
    • (2010) Clin Immunol , vol.134 , pp. 5-24
    • Lundberg, A.M.1    Hansson, G.K.2
  • 4
    • 0033798334 scopus 로고    scopus 로고
    • Atherosclerosis: From lesion formation to plaque activation and endothelial dysfunction
    • Keaney JF. Atherosclerosis: from lesion formation to plaque activation and endothelial dysfunction. Mol Aspects Med 2000; 21: 99-166.
    • (2000) Mol Aspects Med , vol.21 , pp. 99-166
    • Keaney, J.F.1
  • 5
    • 0023614370 scopus 로고
    • Vascular endothelium: Nature's bloodcompatible containera
    • Michael A, Gimbrone JR. Vascular endothelium: nature's bloodcompatible containera. Ann N Y Acad Sci 1987; 516: 5-11.
    • (1987) Ann N Y Acad Sci , vol.516 , pp. 5-11
    • Michael, A.1    Gimbrone, J.R.2
  • 6
    • 0027807211 scopus 로고
    • Rous-Whipple Award Lecture. Atherosclerosis: A defense mechanism gone awry
    • Ross R. Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry. Am J Pathol 1993; 143: 987-1002.
    • (1993) Am J Pathol , vol.143 , pp. 987-1002
    • Ross, R.1
  • 7
    • 0032984208 scopus 로고    scopus 로고
    • Vascular endothelium, hemodynamic forces, and atherogenesis
    • Gimbrone MA, Jr. Vascular endothelium, hemodynamic forces, and atherogenesis. Am J Pathol 1999; 155: 1-5.
    • (1999) Am J Pathol , vol.155 , pp. 1-5
    • Gimbrone Jr., M.A.1
  • 8
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004; 109: III-27-32.
    • (2004) Circulation , vol.109
    • Davignon, J.1    Ganz, P.2
  • 9
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-43.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 10
    • 0036157628 scopus 로고    scopus 로고
    • C-reactive protein and cardiovascular disease: A review of risk prediction and interventions
    • de Ferranti S, Rifai N. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta 2002; 317: 1-15.
    • (2002) Clin Chim Acta , vol.317 , pp. 1-15
    • de Ferranti, S.1    Rifai, N.2
  • 11
    • 20444381235 scopus 로고    scopus 로고
    • Evaluation of Creactive protein measurement for assessing the risk and prognosis in ischemic stroke: A statement for Health Care Professionals From the CRP Pooling Project Members
    • Di Napoli M, Schwaninger M, Cappelli R, et al. Evaluation of Creactive protein measurement for assessing the risk and prognosis in ischemic stroke: a statement for Health Care Professionals From the CRP Pooling Project Members. Stroke 2005; 36: 1316-29.
    • (2005) Stroke , vol.36 , pp. 1316-1329
    • Di Napoli, M.1    Schwaninger, M.2    Cappelli, R.3
  • 12
    • 33845980607 scopus 로고    scopus 로고
    • C-reactive protein: A non-traditional serum marker of cardiovascular risk
    • de Ferranti SD, Rifai N. C-reactive protein: a non-traditional serum marker of cardiovascular risk. Cardiovasc Pathol 2007; 16: 14-21.
    • (2007) Cardiovasc Pathol , vol.16 , pp. 14-21
    • de Ferranti, S.D.1    Rifai, N.2
  • 13
    • 33847261506 scopus 로고    scopus 로고
    • C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    • Sattar N, Murray HM, McConnachie A, et al. C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Circulation 2007; 115: 981-9.
    • (2007) Circulation , vol.115 , pp. 981-989
    • Sattar, N.1    Murray, H.M.2    McConnachie, A.3
  • 14
    • 33847233869 scopus 로고    scopus 로고
    • Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure
    • Kavsak PA, MacRae AR, Newman AM, et al. Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure. Clin Biochem 2007; 40: 326-9.
    • (2007) Clin Biochem , vol.40 , pp. 326-329
    • Kavsak, P.A.1    McRae, A.R.2    Newman, A.M.3
  • 15
    • 0141835079 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and cardiovascular risk: Rationale for screening and primary prevention
    • Ridker PM. High-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary prevention. Am J Cardiol 2003; 92: 17-22.
    • (2003) Am J Cardiol , vol.92 , pp. 17-22
    • Ridker, P.M.1
  • 16
    • 24344490417 scopus 로고    scopus 로고
    • C-reactive protein induces tissue factor expression and promotes smooth muscle and endothelial cell proliferation
    • Cirillo P, Golino P, Calabro P, et al. C-reactive protein induces tissue factor expression and promotes smooth muscle and endothelial cell proliferation. Cardiovasc Res 2005; 68: 47-55.
    • (2005) Cardiovasc Res , vol.68 , pp. 47-55
    • Cirillo, P.1    Golino, P.2    Calabro, P.3
  • 17
    • 67649445969 scopus 로고    scopus 로고
    • Leptin stimulated C-reactive protein production by human coronary artery endothelial cells
    • De Rosa S, Cirillo P, Pacileo M, Di Palma V, Paglia A, Chiariello M. Leptin stimulated C-reactive protein production by human coronary artery endothelial cells. J Vasc Res 2009; 46: 609-17.
    • (2009) J Vasc Res , vol.46 , pp. 609-617
    • De Rosa, S.1    Cirillo, P.2    Pacileo, M.3    Di Palma, V.4    Paglia, A.5    Chiariello, M.6
  • 18
    • 38549148785 scopus 로고    scopus 로고
    • C-reactive protein (CRP): More than just an innocent bystander?
    • Paraskevas KI, Mikhailidis DP. C-reactive protein (CRP): more than just an innocent bystander? Curr Med Res Opin 2008; 24: 75-8.
    • (2008) Curr Med Res Opin , vol.24 , pp. 75-78
    • Paraskevas, K.I.1    Mikhailidis, D.P.2
  • 20
    • 0030983843 scopus 로고    scopus 로고
    • Increased neopterin in patients with chronic and acute coronary syndromes
    • Schumacher M, Halwachs G, Tatzber F, et al. Increased neopterin in patients with chronic and acute coronary syndromes. J Am Coll Cardiol 1997; 30: 703-7.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 703-707
    • Schumacher, M.1    Halwachs, G.2    Tatzber, F.3
  • 21
    • 0037024205 scopus 로고    scopus 로고
    • Prognostic significance of immune activation after acute coronary syndromes
    • Auer J, Berent R, Lassnig E, Weber T, Eber B. Prognostic significance of immune activation after acute coronary syndromes. J Am Coll Cardiol 2002; 39: 1878-88.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1878-1888
    • Auer, J.1    Berent, R.2    Lassnig, E.3    Weber, T.4    Eber, B.5
  • 22
    • 34250785071 scopus 로고    scopus 로고
    • Long-term prognostic value of neopterin: A novel marker of monocyte activation in patients with acute coronary syndrome
    • Ray KK, Morrow DA, Sabatine MS, et al. Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome. Circulation 2007; 115: 3071-8.
    • (2007) Circulation , vol.115 , pp. 3071-3078
    • Ray, K.K.1    Morrow, D.A.2    Sabatine, M.S.3
  • 23
    • 4644337418 scopus 로고    scopus 로고
    • Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris
    • Zouridakis E, Avanzas P, Arroyo-Espliguero R, Fredericks S, Kaski JC. Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris. Circulation 2004; 110: 1747-53.
    • (2004) Circulation , vol.110 , pp. 1747-1753
    • Zouridakis, E.1    Avanzas, P.2    Arroyo-Espliguero, R.3    Fredericks, S.4    Kaski, J.C.5
  • 24
    • 0027459585 scopus 로고
    • Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP
    • Werner-Felmayer G, Werner ER, Fuchs D, et al. Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP. J Biol Chem 1993; 268: 1842-6.
    • (1993) J Biol Chem , vol.268 , pp. 1842-1846
    • Werner-Felmayer, G.1    Werner, E.R.2    Fuchs, D.3
  • 25
    • 0021264311 scopus 로고
    • Immune responseassociated production of neopterin. Release from macrophages primarily under control of interferon-gamma
    • Huber C, Batchelor JR, Fuchs D, et al. Immune responseassociated production of neopterin. Release from macrophages primarily under control of interferon-gamma. J Exp Med 1984; 160: 310-6.
    • (1984) J Exp Med , vol.160 , pp. 310-316
    • Huber, C.1    Batchelor, J.R.2    Fuchs, D.3
  • 26
    • 0027066967 scopus 로고
    • The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases
    • Fuchs D, Weiss G, Reibnegger G, Wachter H. The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases. Crit Rev Clin Lab Sci 1992; 29: 307-41.
    • (1992) Crit Rev Clin Lab Sci , vol.29 , pp. 307-341
    • Fuchs, D.1    Weiss, G.2    Reibnegger, G.3    Wachter, H.4
  • 28
    • 0023186976 scopus 로고
    • Determination of neopterin in serum and urine
    • Werner ER, Bichler A, Daxenbichler G, et al. Determination of neopterin in serum and urine. Clin Chem 1987; 33: 62-6.
    • (1987) Clin Chem , vol.33 , pp. 62-66
    • Werner, E.R.1    Bichler, A.2    Daxenbichler, G.3
  • 32
    • 0032433248 scopus 로고    scopus 로고
    • Endothelial derived vasoactive factors and leukocyte derived inflammatory mediators in subjects with asymptomatic atherosclerosis
    • Anwaar I, Gottsater A, Hedblad B, Palmqvist B, Mattiasson I, Lindgarde F. Endothelial derived vasoactive factors and leukocyte derived inflammatory mediators in subjects with asymptomatic atherosclerosis. Angiology 1998; 49: 957-66.
    • (1998) Angiology , vol.49 , pp. 957-966
    • Anwaar, I.1    Gottsater, A.2    Hedblad, B.3    Palmqvist, B.4    Mattiasson, I.5    Lindgarde, F.6
  • 33
    • 0025775730 scopus 로고
    • Elevated serum neopterin levels in atherosclerosis
    • Tatzber F, Rabl H, Koriska K, et al. Elevated serum neopterin levels in atherosclerosis. Atherosclerosis 1991; 89: 203-8.
    • (1991) Atherosclerosis , vol.89 , pp. 203-208
    • Tatzber, F.1    Rabl, H.2    Koriska, K.3
  • 34
    • 14644425246 scopus 로고    scopus 로고
    • Elevated serum neopterin predicts future adverse cardiac events in patients with chronic stable angina pectoris
    • Avanzas P, Arroyo-Espliguero R, Quiles J, Roy D, Kaski JC. Elevated serum neopterin predicts future adverse cardiac events in patients with chronic stable angina pectoris. Eur Heart J 2005; 26: 457-63.
    • (2005) Eur Heart J , vol.26 , pp. 457-463
    • Avanzas, P.1    Arroyo-Espliguero, R.2    Quiles, J.3    Roy, D.4    Kaski, J.C.5
  • 35
    • 66449099309 scopus 로고    scopus 로고
    • Neopterin as a predictor of total and cardiovascular mortality in individuals undergoing angiography in the Ludwigshafen risk and cardiovascular health study
    • Grammer TB, Fuchs D, Boehm BO, Winkelmann BR, Maerz W. Neopterin as a predictor of total and cardiovascular mortality in individuals undergoing angiography in the Ludwigshafen risk and cardiovascular health study. Clin Chem 2009; 55: 1135-46.
    • (2009) Clin Chem , vol.55 , pp. 1135-1146
    • Grammer, T.B.1    Fuchs, D.2    Boehm, B.O.3    Winkelmann, B.R.4    Maerz, W.5
  • 36
    • 67349273640 scopus 로고    scopus 로고
    • Neopterin, CD4+CD28- lymphocytes and the extent and severity of coronary artery disease
    • Alber HF, Duftner C, Wanitschek M, et al. Neopterin, CD4+CD28- lymphocytes and the extent and severity of coronary artery disease. Int J Cardiol 2009; 135: 27-35.
    • (2009) Int J Cardiol , vol.135 , pp. 27-35
    • Alber, H.F.1    Duftner, C.2    Wanitschek, M.3
  • 37
    • 1442275277 scopus 로고    scopus 로고
    • Prognostic value of neopterin levels in treated patients with hypertension and chest pain but without obstructive coronary artery disease
    • Avanzas P, Arroyo-Espliguero R, Cosin-Sales J, Quiles J, Zouridakis E, Kaski JC. Prognostic value of neopterin levels in treated patients with hypertension and chest pain but without obstructive coronary artery disease. Am J Cardiol 2004; 93: 627-9.
    • (2004) Am J Cardiol , vol.93 , pp. 627-629
    • Avanzas, P.1    Arroyo-Espliguero, R.2    Cosin-Sales, J.3    Quiles, J.4    Zouridakis, E.5    Kaski, J.C.6
  • 38
    • 70349248652 scopus 로고    scopus 로고
    • Neopterin predicts the risk for fatal ischemic heart disease in type 2 diabetes mellitus: Long-term follow-up of the HUNT 1 study
    • Vengen IT, Dale AC, Wiseth R, Midthjell K, Videm V. Neopterin predicts the risk for fatal ischemic heart disease in type 2 diabetes mellitus: long-term follow-up of the HUNT 1 study. Atherosclerosis 2009; 207: 239-44.
    • (2009) Atherosclerosis , vol.207 , pp. 239-244
    • Vengen, I.T.1    Dale, A.C.2    Wiseth, R.3    Midthjell, K.4    Videm, V.5
  • 39
    • 0034022382 scopus 로고    scopus 로고
    • Increased serum neopterin: A marker of coronary artery disease activity in women
    • Garcia-Moll X, Cole D, Zouridakis E, Kaski JC. Increased serum neopterin: a marker of coronary artery disease activity in women. Heart 2000; 83: 346-50.
    • (2000) Heart , vol.83 , pp. 346-350
    • Garcia-Moll, X.1    Cole, D.2    Zouridakis, E.3    Kaski, J.C.4
  • 40
    • 54849433571 scopus 로고    scopus 로고
    • Inflammation and hemostasis biomarkers for predicting stroke in postmenopausal women: The women's health initiative observational study
    • Kaplan RC, McGinn AP, Baird AE, et al. Inflammation and hemostasis biomarkers for predicting stroke in postmenopausal women: the women's health initiative observational study. J Stroke Cerebrovasc Dis 2008; 17: 344-55.
    • (2008) J Stroke Cerebrovasc Dis , vol.17 , pp. 344-355
    • Kaplan, R.C.1    McGinn, A.P.2    Baird, A.E.3
  • 41
    • 43149121315 scopus 로고    scopus 로고
    • Comparison of neopterin levels in patients with coronary artery ectasia vs. patients with obstructive coronary artery disease
    • Sahin M, Varol E, Ozaydin M, et al. Comparison of neopterin levels in patients with coronary artery ectasia vs. patients with obstructive coronary artery disease. South Med J 2008; 101: 476-9.
    • (2008) South Med J , vol.101 , pp. 476-479
    • Sahin, M.1    Varol, E.2    Ozaydin, M.3
  • 42
    • 50249102875 scopus 로고    scopus 로고
    • Serum neopterin, nitric oxide, inducible nitric oxide synthase and tumor necrosis factor alpha levels in patients with ischemic heart disease
    • Djordjevic V, Stojanovic I, Cosic V, et al. Serum neopterin, nitric oxide, inducible nitric oxide synthase and tumor necrosis factor alpha levels in patients with ischemic heart disease. Clin Chem Lab Med 2008; 46: 1149-55.
    • (2008) Clin Chem Lab Med , vol.46 , pp. 1149-1155
    • Djordjevic, V.1    Stojanovic, I.2    Cosic, V.3
  • 43
    • 0034654628 scopus 로고    scopus 로고
    • Serum neopterin and complex stenosis morphology in patients with unstable angina
    • Garcia-Moll X, Coccolo F, Cole D, Kaski JC. Serum neopterin and complex stenosis morphology in patients with unstable angina. J Am Coll Cardiol 2000; 35: 956-62.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 956-962
    • Garcia-Moll, X.1    Coccolo, F.2    Cole, D.3    Kaski, J.C.4
  • 44
    • 10744226924 scopus 로고    scopus 로고
    • Plasma concentrations of monocyte chemoattractant protein 1 (MCP-1) and neopterin in the coronary circulation of patients with coronary artery disease association with the severity of coronary atherosclerosis
    • Tanaka T, Nakamura Y, Nasuno A, et al. Plasma concentrations of monocyte chemoattractant protein 1 (MCP-1) and neopterin in the coronary circulation of patients with coronary artery disease association with the severity of coronary atherosclerosis. Circ J 2004; 68: 114-20.
    • (2004) Circ J , vol.68 , pp. 114-120
    • Tanaka, T.1    Nakamura, Y.2    Nasuno, A.3
  • 45
    • 33746316270 scopus 로고    scopus 로고
    • Usefulness of neopterin levels and left ventricular function for risk assessment in survivors of acute myocardial infarction
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Garcia-Gonzalez M. Usefulness of neopterin levels and left ventricular function for risk assessment in survivors of acute myocardial infarction. Int J Cardiol 2006; 111: 318-20.
    • (2006) Int J Cardiol , vol.111 , pp. 318-320
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Garcia-Gonzalez, M.3
  • 46
    • 0242492234 scopus 로고    scopus 로고
    • Usefulness of elevated neopterin and C-reactive protein levels in predicting cardiovascular events in patients with non-Q-wave myocardial infarction
    • van Haelst PL, Liem A, van Boven AJ, et al. Usefulness of elevated neopterin and C-reactive protein levels in predicting cardiovascular events in patients with non-Q-wave myocardial infarction. Am J Cardiol 2003; 92: 1201-3.
    • (2003) Am J Cardiol , vol.92 , pp. 1201-1203
    • van Haelst, P.L.1    Liem, A.2    van Boven, A.J.3
  • 47
    • 0037485567 scopus 로고    scopus 로고
    • Neopterin levels in patients with coronary artery disease are independent of chlamydia pneumoniae seropositivity
    • Smith DA, Zouridakis EG, Mariani M, Fredericks S, Cole D, Kaski JC. Neopterin levels in patients with coronary artery disease are independent of chlamydia pneumoniae seropositivity. Am Heart J 2003; 146: 69-74.
    • (2003) Am Heart J , vol.146 , pp. 69-74
    • Smith, D.A.1    Zouridakis, E.G.2    Mariani, M.3    Fredericks, S.4    Cole, D.5    Kaski, J.C.6
  • 48
    • 53949090315 scopus 로고    scopus 로고
    • Elevated serum neopterin levels and adverse cardiac events at 6 months follow-up in Mediterranean patients with non-ST-segment elevation acute coronary syndrome
    • Kaski JC, Consuegra-Sanchez L, Fernandez-Berges DJ, et al. Elevated serum neopterin levels and adverse cardiac events at 6 months follow-up in Mediterranean patients with non-ST-segment elevation acute coronary syndrome. Atherosclerosis 2008; 201: 176-83.
    • (2008) Atherosclerosis , vol.201 , pp. 176-183
    • Kaski, J.C.1    Consuegra-Sanchez, L.2    Fernandez-Berges, D.J.3
  • 49
    • 57349136369 scopus 로고    scopus 로고
    • Light-dark variations in neopterin serum levels in patients with STsegment elevation acute coronary syndrome undergoing primary angioplasty
    • García-González MJ, Domínguez-Rodríguez A, Abreu-González P. Light-dark variations in neopterin serum levels in patients with STsegment elevation acute coronary syndrome undergoing primary angioplasty. Rev Esp Cardiol 2008; 61: 1280-6.
    • (2008) Rev Esp Cardiol , vol.61 , pp. 1280-1286
    • García-González, M.J.1    Domínguez-Rodríguez, A.2    Abreu-González, P.3
  • 50
    • 0022384056 scopus 로고
    • Circadian variation in the frequency of onset of acute myocardial infarction
    • Muller JE, Stone PH, Turi ZG, et al. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med 1985; 313: 1315-22.
    • (1985) N Engl J Med , vol.313 , pp. 1315-1322
    • Muller, J.E.1    Stone, P.H.2    Turi, Z.G.3
  • 51
    • 0019500299 scopus 로고
    • Studies on the bioperiodicity of the immune response. I. Circadian rhythms of human T, B, and K cell traffic in the peripheral blood
    • Abo T, Kawate T, Itoh K, Kumagai K. Studies on the bioperiodicity of the immune response. I. Circadian rhythms of human T, B, and K cell traffic in the peripheral blood. J Immunol 1981; 126: 1360-3.
    • (1981) J Immunol , vol.126 , pp. 1360-1363
    • Abo, T.1    Kawate, T.2    Itoh, K.3    Kumagai, K.4
  • 52
    • 0142091704 scopus 로고    scopus 로고
    • HMGCoA Reductase Inhibitors are associated with decreased serum neopterin levels in stable coronary artery disease
    • Walter RB, Fuchs D, Weiss G, Walter TR, Reinhart WH. HMGCoA Reductase Inhibitors are associated with decreased serum neopterin levels in stable coronary artery disease. Clin Chem Lab Med 2003; 41: 1314-9.
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1314-1319
    • Walter, R.B.1    Fuchs, D.2    Weiss, G.3    Walter, T.R.4    Reinhart, W.H.5
  • 54
    • 0002213460 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and cardiovascular risk: An epidemiologic view
    • Ridker P. Inflammation, atherosclerosis, and cardiovascular risk: an epidemiologic view. Blood Coagul Fibrinolysis 1999; 10: S9-12.
    • (1999) Blood Coagul Fibrinolysis , vol.10
    • Ridker, P.1
  • 55
    • 0037316358 scopus 로고    scopus 로고
    • Atorvastatin suppresses interferon-gamma induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines
    • Neurauter G, Wirleitner B, Laich A, Schennach H, Weiss G, Fuchs D. Atorvastatin suppresses interferon-gamma induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines. Clin Exp Immunol 2003; 131: 264-7.
    • (2003) Clin Exp Immunol , vol.131 , pp. 264-267
    • Neurauter, G.1    Wirleitner, B.2    Laich, A.3    Schennach, H.4    Weiss, G.5    Fuchs, D.6
  • 56
    • 35648937457 scopus 로고    scopus 로고
    • HMG-CoA Reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells
    • Cirillo P, Pacileo M, De Rosa S, et al. HMG-CoA Reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells. J Vasc Res 2007; 44: 460-70.
    • (2007) J Vasc Res , vol.44 , pp. 460-470
    • Cirillo, P.1    Pacileo, M.2    De Rosa, S.3
  • 57
    • 0346203296 scopus 로고    scopus 로고
    • Increasing plasma fibrinogen, but unchanged levels of intraplatelet cyclic nucleotides, plasma endothelin-1, factor VII, and neopterin during cholesterol lowering with fluvastatin
    • Gottsäter A, Anwaar I, Lind P, Mattiasson I, Lindgärde F. Increasing plasma fibrinogen, but unchanged levels of intraplatelet cyclic nucleotides, plasma endothelin-1, factor VII, and neopterin during cholesterol lowering with fluvastatin. Blood Coagul Fibrinolysis 1999; 10: 133-40.
    • (1999) Blood Coagul Fibrinolysis , vol.10 , pp. 133-140
    • Gottsäter, A.1    Anwaar, I.2    Lind, P.3    Mattiasson, I.4    Lindgärde, F.5
  • 59
    • 36749013036 scopus 로고    scopus 로고
    • Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions
    • Adachi T, Naruko T, Itoh A, et al. Neopterin is associated with plaque inflammation and destabilisation in human coronary atherosclerotic lesions. Heart 2007; 93: 1537-41.
    • (2007) Heart , vol.93 , pp. 1537-1541
    • Adachi, T.1    Naruko, T.2    Itoh, A.3
  • 60
    • 0019966134 scopus 로고
    • Survival of medically treated patients in the coronary artery surgery study (CASS) registry
    • Mock MB, Ringqvist I, Fisher LD, et al. Survival of medically treated patients in the coronary artery surgery study (CASS) registry. Circulation 1982; 66: 562-8.
    • (1982) Circulation , vol.66 , pp. 562-568
    • Mock, M.B.1    Ringqvist, I.2    Fisher, L.D.3
  • 61
    • 0018752945 scopus 로고
    • Survival in patients with coronary disease
    • Hammermeister KE. Survival in patients with coronary disease. Circulation 1979; 60: 1427.
    • (1979) Circulation , vol.60 , pp. 1427
    • Hammermeister, K.E.1
  • 62
    • 0035058586 scopus 로고    scopus 로고
    • The role of interleukin-6 in the failing heart
    • Wollert KC, Drexler H. The role of interleukin-6 in the failing heart. Heart Fail Rev 2001; 6:95-103.
    • (2001) Heart Fail Rev , vol.6 , pp. 95-103
    • Wollert, K.C.1    Drexler, H.2
  • 63
    • 0032515950 scopus 로고    scopus 로고
    • Pathophysiologically relevant concentrations of tumor necrosis factor-{alpha} promote progressive left ventricular dysfunction and remodeling in rats
    • Bozkurt B, Kribbs SB, Clubb FJ, Jr., et al. Pathophysiologically relevant concentrations of tumor necrosis factor-{alpha} promote progressive left ventricular dysfunction and remodeling in rats. Circulation 1998; 97: 1382-91.
    • (1998) Circulation , vol.97 , pp. 1382-1391
    • Bozkurt, B.1    Kribbs, S.B.2    Clubb Jr., F.J.3
  • 64
    • 0035064105 scopus 로고    scopus 로고
    • Recent insights into the role of tumor necrosis factor in the failing heart
    • Mann DL. Recent insights into the role of tumor necrosis factor in the failing heart. Heart Fail Rev 2001; 6: 71-80.
    • (2001) Heart Fail Rev , vol.6 , pp. 71-80
    • Mann, D.L.1
  • 65
    • 0029871896 scopus 로고    scopus 로고
    • Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD)
    • Torre-Amione G, Kapadia S, Benedict C, Oral H, Young JB, Mann DL. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the studies of left ventricular dysfunction (SOLVD). J Am Coll Cardiol 1996; 27: 1201-6.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 1201-1206
    • Torre-Amione, G.1    Kapadia, S.2    Benedict, C.3    Oral, H.4    Young, J.B.5    Mann, D.L.6
  • 66
    • 0029670957 scopus 로고    scopus 로고
    • Tumor necrosis factor- {alpha} and tumor necrosis factor receptors in the failing human heart
    • Torre-Amione G, Kapadia S, Lee J, et al. Tumor necrosis factor- {alpha} and tumor necrosis factor receptors in the failing human heart. Circulation 1996; 93: 704-11.
    • (1996) Circulation , vol.93 , pp. 704-711
    • Torre-Amione, G.1    Kapadia, S.2    Lee, J.3
  • 67
    • 0021019401 scopus 로고
    • Neopterin as a new biochemical marker for diagnosis of allograft rejection. Experience based upon evaluation of 100 consecutive cases
    • Margreiter R, Fuchs D, Hausen A, et al. Neopterin as a new biochemical marker for diagnosis of allograft rejection. Experience based upon evaluation of 100 consecutive cases. Transplantation 1983; 6: 650-3.
    • (1983) Transplantation , vol.6 , pp. 650-653
    • Margreiter, R.1    Fuchs, D.2    Hausen, A.3
  • 68
    • 20444375476 scopus 로고    scopus 로고
    • Mechanism of neopterin- induced myocardial dysfunction in the isolated perfused rat heart
    • Balogh A, Mittermayr M, Schlager A, et al. Mechanism of neopterin- induced myocardial dysfunction in the isolated perfused rat heart. Biochim Biophys Acta 2005; 1724:17-22.
    • (2005) Biochim Biophys Acta , vol.1724 , pp. 17-22
    • Balogh, A.1    Mittermayr, M.2    Schlager, A.3
  • 69
    • 0027513924 scopus 로고
    • Effect of pteridine derivatives on intracellular calcium concentration in human monocytic cells
    • Wöll E, Weiss G, Fuchs D, Lang F, Wachter H. Effect of pteridine derivatives on intracellular calcium concentration in human monocytic cells. FEBS Lett 1993; 318: 249-52.
    • (1993) FEBS Lett , vol.318 , pp. 249-252
    • Wöll, E.1    Weiss, G.2    Fuchs, D.3    Lang, F.4    Wachter, H.5
  • 70
    • 0035999166 scopus 로고    scopus 로고
    • Neopterin inhibits ATPinduced calcium release in alveolar epithelial cells in vitro
    • Hoffmann G, Gollnick F, Meyer R. Neopterin inhibits ATPinduced calcium release in alveolar epithelial cells in vitro. Mediators Inflamm 2002; 3: 181-5.
    • (2002) Mediators Inflamm , vol.3 , pp. 181-185
    • Hoffmann, G.1    Gollnick, F.2    Meyer, R.3
  • 71
    • 33749021650 scopus 로고    scopus 로고
    • Cardiac function, inflammatory mediators and mortality in critical limb ischemia
    • Barani J, Mattiasson I, Lindblad B, Gottsater A. Cardiac function, inflammatory mediators and mortality in critical limb ischemia. Angiology 2006; 57: 437-44.
    • (2006) Angiology , vol.57 , pp. 437-444
    • Barani, J.1    Mattiasson, I.2    Lindblad, B.3    Gottsater, A.4
  • 73
    • 77954295391 scopus 로고    scopus 로고
    • Neopterin as a prognostic marker in patients with chronic heart failure
    • Wietlicka-Kokoszanek I, Jablecka A, Smolarek I, et al. Neopterin as a prognostic marker in patients with chronic heart failure. Med Sci Monit 2010; 16: CR232-7.
    • (2010) Med Sci Monit , vol.16
    • Wietlicka-Kokoszanek, I.1    Jablecka, A.2    Smolarek, I.3
  • 74
    • 77957877207 scopus 로고    scopus 로고
    • Neopterin -- Marker of coronary artery disease activity or extension in patients with chronic stable angina?
    • Avanzas P, Arroyo-Espliguero R, Kaski JC. Neopterin -- Marker of coronary artery disease activity or extension in patients with chronic stable angina? Int J Cardiol 2010; 144: 74-5.
    • (2010) Int J Cardiol , vol.144 , pp. 74-75
    • Avanzas, P.1    Arroyo-Espliguero, R.2    Kaski, J.C.3
  • 75
    • 77955270286 scopus 로고    scopus 로고
    • Neopterin predicts left ventricular remodeling in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
    • Dominguez-Rodriguez A, Abreu-Gonzalez P, Avanzas P, Laynez-Cerdeña I, Kaski JC. Neopterin predicts left ventricular remodeling in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Atherosclerosis 2010; 211: 574-8.
    • (2010) Atherosclerosis , vol.211 , pp. 574-578
    • Dominguez-Rodriguez, A.1    Abreu-Gonzalez, P.2    Avanzas, P.3    Laynez-Cerdeña, I.4    Kaski, J.C.5
  • 76
    • 0026608952 scopus 로고
    • Serum kynurenine and neopterin concentrations in patients with cardiomyopathy
    • Rudzite V, Skards JI, Fuchs D, Reibnegger G, Wachter H. Serum kynurenine and neopterin concentrations in patients with cardiomyopathy. Immunol Lett 1992; 32: 125-9.
    • (1992) Immunol Lett , vol.32 , pp. 125-129
    • Rudzite, V.1    Skards, J.I.2    Fuchs, D.3    Reibnegger, G.4    Wachter, H.5
  • 78
    • 0037056082 scopus 로고    scopus 로고
    • Cardiovascular manifestations of HIV infection
    • Barbaro G. Cardiovascular manifestations of HIV infection. Circulation 2002; 106: 1420-5.
    • (2002) Circulation , vol.106 , pp. 1420-1425
    • Barbaro, G.1
  • 79
    • 0033621142 scopus 로고    scopus 로고
    • Intensity of myocardial expression of inducible nitric oxide synthase influences the clinical course of human immunodeficiency virus-associated cardiomyopathy
    • Barbaro G, Di Lorenzo G, Soldini M, et al. Intensity of myocardial expression of inducible nitric oxide synthase influences the clinical course of human immunodeficiency virus-associated cardiomyopathy. Circulation 1999; 100: 933-9.
    • (1999) Circulation , vol.100 , pp. 933-939
    • Barbaro, G.1    Di Lorenzo, G.2    Soldini, M.3
  • 80
    • 77955866621 scopus 로고    scopus 로고
    • High serum level of neopterin is a risk factor of patients with heart failure
    • Sasaki T, Takeishi Y, Suzuki S, et al. High serum level of neopterin is a risk factor of patients with heart failure. Int J Cardiol 2010; 145: 318.
    • (2010) Int J Cardiol , vol.145 , pp. 318
    • Sasaki, T.1    Takeishi, Y.2    Suzuki, S.3
  • 81
    • 77957255542 scopus 로고    scopus 로고
    • Early expression of pro- and anti-inflammatory cytokines in left ventricular assist device recipients with multiple organ failure syndrome
    • Caruso R, Trunfio S, Milazzo F, et al. Early expression of pro- and anti-inflammatory cytokines in left ventricular assist device recipients with multiple organ failure syndrome. ASAIO J 2010; 56: 313-8.
    • (2010) ASAIO J , vol.56 , pp. 313-318
    • Caruso, R.1    Trunfio, S.2    Milazzo, F.3
  • 82
    • 77953000267 scopus 로고    scopus 로고
    • Systemic markers of inflammation are associated with cardiac allograft vasculopathy and an increased intimal inflammatory component
    • Arora S, Gunther A, Wennerblom B, et al. Systemic markers of inflammation are associated with cardiac allograft vasculopathy and an increased intimal inflammatory component. Am J Transplant 2010; 10: 1428-36.
    • (2010) Am J Transplant , vol.10 , pp. 1428-1436
    • Arora, S.1    Gunther, A.2    Wennerblom, B.3
  • 83
    • 0033900011 scopus 로고    scopus 로고
    • Peroxynitrite is a major contributor to Cytokine-Induced Myocardial Contractile Failure
    • Ferdinandy P, Danial H, Ambrus I, Rothery RA, Schulz R. Peroxynitrite is a major contributor to Cytokine-Induced Myocardial Contractile Failure. Circ Res 2000; 87: 241-7.
    • (2000) Circ Res , vol.87 , pp. 241-247
    • Ferdinandy, P.1    Danial, H.2    Ambrus, I.3    Rothery, R.A.4    Schulz, R.5
  • 84
    • 0037453028 scopus 로고    scopus 로고
    • Oxidative Stress Mediates Tumor Necrosis Factor-{alpha}-Induced Mitochondrial DNA damage and dysfunction in cardiac myocytes
    • Suematsu N, Tsutsui H, Wen J, et al. Oxidative Stress Mediates Tumor Necrosis Factor-{alpha}-Induced Mitochondrial DNA damage and dysfunction in cardiac myocytes. Circulation 2003; 107: 1418-23.
    • (2003) Circulation , vol.107 , pp. 1418-1423
    • Suematsu, N.1    Tsutsui, H.2    Wen, J.3
  • 85
    • 0034995893 scopus 로고    scopus 로고
    • Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts
    • Siwik DA, Pagano PJ, Colucci WS. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol 2001; 280: C53-60.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Siwik, D.A.1    Pagano, P.J.2    Colucci, W.S.3
  • 86
    • 0036945213 scopus 로고    scopus 로고
    • Tumor necrosis factor-_-induced AT1 receptor upregulation enhances angiotensin ii-mediated cardiac fibroblast responses that favor fibrosis
    • Peng J, Gurantz D, Tran V, Cowling RT, Greenberg BH. Tumor necrosis factor-_-induced AT1 receptor upregulation enhances angiotensin ii-mediated cardiac fibroblast responses that favor fibrosis. Circ Res 2002; 91: 1119-26.
    • (2002) Circ Res , vol.91 , pp. 1119-1126
    • Peng, J.1    Gurantz, D.2    Tran, V.3    Cowling, R.T.4    Greenberg, B.H.5
  • 87
    • 33846477338 scopus 로고    scopus 로고
    • Peripheral arterial disease
    • Aronow W. Peripheral arterial disease. Geriatrics 2007; 62: 19-25.
    • (2007) Geriatrics , vol.62 , pp. 19-25
    • Aronow, W.1
  • 88
    • 0032710356 scopus 로고    scopus 로고
    • Clinical efficacy of an automated high-sensitivity C-Reactive protein assay
    • Rifai N, Tracy RP, Ridker PM. Clinical efficacy of an automated high-sensitivity C-Reactive protein assay. Clin Chem 1999; 45: 2136-41.
    • (1999) Clin Chem , vol.45 , pp. 2136-2141
    • Rifai, N.1    Tracy, R.P.2    Ridker, P.M.3
  • 89
    • 4043152705 scopus 로고    scopus 로고
    • Prevalence of and risk factors for peripheral arterial disease in the United States: Results from the National Health and Nutrition Examination Survey, 1999-2000
    • Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation 2004; 110: 738-43.
    • (2004) Circulation , vol.110 , pp. 738-743
    • Selvin, E.1    Erlinger, T.P.2
  • 90
    • 0038306318 scopus 로고    scopus 로고
    • Relation of levels of hemostatic factors and inflammatory markers to the ankle brachial index
    • McDermott MM, Green D, Greenland P, et al. Relation of levels of hemostatic factors and inflammatory markers to the ankle brachial index. Am J Cardiol 2003; 92: 194-9.
    • (2003) Am J Cardiol , vol.92 , pp. 194-199
    • McDermott, M.M.1    Green, D.2    Greenland, P.3
  • 91
    • 32544439819 scopus 로고    scopus 로고
    • Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis: The edinburgh artery study
    • Tzoulaki I, Murray GD, Price JF, et al. Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis: the edinburgh artery study. Am J Epidemiol 2006; 163: 334-41.
    • (2006) Am J Epidemiol , vol.163 , pp. 334-341
    • Tzoulaki, I.1    Murray, G.D.2    Price, J.F.3
  • 92
    • 20144370683 scopus 로고    scopus 로고
    • C-reactive protein and peripheral artery disease among japanese elderly: The tsurugaya project
    • Hozawa A, Ohmori K, Kuriyama S, et al. C-reactive protein and peripheral artery disease among japanese elderly: the tsurugaya project. Hypertens Res 2004; 27: 955-61.
    • (2004) Hypertens Res , vol.27 , pp. 955-961
    • Hozawa, A.1    Ohmori, K.2    Kuriyama, S.3
  • 93
    • 23644444800 scopus 로고    scopus 로고
    • Patterns of inflammation associated with peripheral arterial disease: The InCHIANTI study
    • McDermott MM, Guralnik JM, Corsi A, et al. Patterns of inflammation associated with peripheral arterial disease: The InCHIANTI study. Am Heart J 2005; 150: 276-81.
    • (2005) Am Heart J , vol.150 , pp. 276-281
    • McDermott, M.M.1    Guralnik, J.M.2    Corsi, A.3
  • 94
    • 0035897688 scopus 로고    scopus 로고
    • Novel risk factors for systemic atherosclerosis: A comparison of C-Reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease
    • Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-Reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 2001; 285: 2481-5.
    • (2001) JAMA , vol.285 , pp. 2481-2485
    • Ridker, P.M.1    Stampfer, M.J.2    Rifai, N.3
  • 95
    • 0037072452 scopus 로고    scopus 로고
    • Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men
    • Pradhan AD, Rifai N, Ridker PM. Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men. Circulation 2002; 106: 820-5.
    • (2002) Circulation , vol.106 , pp. 820-825
    • Pradhan, A.D.1    Rifai, N.2    Ridker, P.M.3
  • 96
    • 22044452583 scopus 로고    scopus 로고
    • Inflammatory mediators are associated with 1-year mortality in critical limb ischemia
    • Barani J, Nilsson J-Å, Mattiasson I, Lindblad B, Gottsäter A. Inflammatory mediators are associated with 1-year mortality in critical limb ischemia. J Vasc Surg 2005; 42: 75-80.
    • (2005) J Vasc Surg , vol.42 , pp. 75-80
    • Barani, J.1    Nilsson, J.-A.2    Mattiasson, I.3    Lindblad, B.4    Gottsäter, A.5
  • 97
    • 33847673520 scopus 로고    scopus 로고
    • Are there differences of inflammatory bio-markers between diabetic and non-diabetic patients with critical limb ischemia?
    • Bertz L, Barani J, Gottsäter A, Nilsson P, Mattiasson I, Lindblad B. Are there differences of inflammatory bio-markers between diabetic and non-diabetic patients with critical limb ischemia? Int Angiol 2006; 25: 370-7.
    • (2006) Int Angiol , vol.25 , pp. 370-377
    • Bertz, L.1    Barani, J.2    Gottsäter, A.3    Nilsson, P.4    Mattiasson, I.5    Lindblad, B.6
  • 98
    • 0032849727 scopus 로고    scopus 로고
    • Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries
    • Erren M, Reinecke H, Junker R, et al. Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries. Arterioscler Thromb Vasc Biol 1999; 19: 2355-63.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2355-2363
    • Erren, M.1    Reinecke, H.2    Junker, R.3
  • 99
    • 0016197163 scopus 로고
    • Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates
    • Garcia J, Kamijyo Y. Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates. J Neuropathol Exp Neurol 1974; 33: 408-21.
    • (1974) J Neuropathol Exp Neurol , vol.33 , pp. 408-421
    • Garcia, J.1    Kamijyo, Y.2
  • 100
    • 0015351633 scopus 로고
    • Cerebrospinal fluid cytology after stroke
    • Sörnäs R, Ostlund H, Müller R. Cerebrospinal fluid cytology after stroke. Arch Neurol 1972; 26: 489-501.
    • (1972) Arch Neurol , vol.26 , pp. 489-501
    • Sörnäs, R.1    Ostlund, H.2    Müller, R.3
  • 101
    • 0026667919 scopus 로고
    • Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke
    • Kochanek PM, Hallenbeck JM. Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 1992; 23: 1367-79.
    • (1992) Stroke , vol.23 , pp. 1367-1379
    • Kochanek, P.M.1    Hallenbeck, J.M.2
  • 102
    • 0031983359 scopus 로고    scopus 로고
    • Neopterin concentrations in cerebrospinal fluid and serum as an aid in differentiating central nervous system and peripheral infections in children
    • Millner MM, Franthal W, Thalhammer GH, et al. Neopterin concentrations in cerebrospinal fluid and serum as an aid in differentiating central nervous system and peripheral infections in children. Clin Chem 1998; 44: 161-7.
    • (1998) Clin Chem , vol.44 , pp. 161-167
    • Millner, M.M.1    Franthal, W.2    Thalhammer, G.H.3
  • 103
    • 0035889717 scopus 로고    scopus 로고
    • Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke
    • Grau AJ, Reis A, Buggle F, et al. Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke. J Neurol Sci 2001; 192: 41-7.
    • (2001) J Neurol Sci , vol.192 , pp. 41-47
    • Grau, A.J.1    Reis, A.2    Buggle, F.3
  • 104
    • 33847790840 scopus 로고    scopus 로고
    • Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production
    • Emsley H, Smith C, Gavin C, et al. Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production. BMC Neurol 2007; 7: 5.
    • (2007) BMC Neurol , vol.7 , pp. 5
    • Emsley, H.1    Smith, C.2    Gavin, C.3
  • 106
    • 54049098509 scopus 로고    scopus 로고
    • Detection of neopterin as parameter of potential monocyte activation in patients with acute ischemic stroke
    • Cojocaru I, Cojocaru M, Burcin C, Atanasiu A. Detection of neopterin as parameter of potential monocyte activation in patients with acute ischemic stroke. Rom J Intern Med 2007; 45: 365-9.
    • (2007) Rom J Intern Med , vol.45 , pp. 365-369
    • Cojocaru, I.1    Cojocaru, M.2    Burcin, C.3    Atanasiu, A.4
  • 107
    • 0345471483 scopus 로고    scopus 로고
    • Increasing plasma neopterin and persistent plasma endothelin during followup after acute cerebral ischemia
    • Anwaar I, Gottsater A, Lindgarde F, Mattiasson I. Increasing plasma neopterin and persistent plasma endothelin during followup after acute cerebral ischemia. Angiology 1999; 50: 1-8.
    • (1999) Angiology , vol.50 , pp. 1-8
    • Anwaar, I.1    Gottsater, A.2    Lindgarde, F.3    Mattiasson, I.4
  • 108
    • 0028264157 scopus 로고
    • Increased concentrations of neopterin in carotid atherosclerosis
    • Weiss G, Willeit J, Kiechl S, et al. Increased concentrations of neopterin in carotid atherosclerosis. Atherosclerosis 1994; 106: 263-71.
    • (1994) Atherosclerosis , vol.106 , pp. 263-271
    • Weiss, G.1    Willeit, J.2    Kiechl, S.3
  • 109
    • 74749095534 scopus 로고    scopus 로고
    • Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris
    • Sugioka K, Naruko T, Hozumi T, et al. Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris. Atherosclerosis 2009; 208: 524-30.
    • (2009) Atherosclerosis , vol.208 , pp. 524-530
    • Sugioka, K.1    Naruko, T.2    Hozumi, T.3
  • 110
    • 0035852662 scopus 로고    scopus 로고
    • Augmentation of postnatal neovascularization with autologous bone marrow transplantation
    • Shintani S, Murohara T, Ikeda H, et al. Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation 2001; 103: 897-903.
    • (2001) Circulation , vol.103 , pp. 897-903
    • Shintani, S.1    Murohara, T.2    Ikeda, H.3
  • 111
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher A, Schuster M, Szabolcs M, et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001; 4: 430-6.
    • (2001) Nat Med , vol.4 , pp. 430-436
    • Kocher, A.1    Schuster, M.2    Szabolcs, M.3
  • 112
    • 33748899449 scopus 로고    scopus 로고
    • Transcoronary transplantation of progenitor cells after myocardial infarction
    • Assmus B, Honold J, Schachinger V, et al. Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med 2006; 355: 1222-32.
    • (2006) N Engl J Med , vol.355 , pp. 1222-1232
    • Assmus, B.1    Honold, J.2    Schachinger, V.3
  • 113
    • 0037044406 scopus 로고    scopus 로고
    • Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans
    • Strauer BE, Brehm M, Zeus T, et al. Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 2002; 106: 1913-8.
    • (2002) Circulation , vol.106 , pp. 1913-1918
    • Strauer, B.E.1    Brehm, M.2    Zeus, T.3
  • 114
    • 0242637112 scopus 로고    scopus 로고
    • Infarct remodeling after intracoronary progenitor cell treatment in patients with acute Myocardial Infarction (TOPCARE-AMI): Mechanistic insights from serial contrast-enhanced magnetic resonance imaging
    • Britten MB, Abolmaali ND, Assmus B, et al. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute Myocardial Infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation 2003; 108: 2212-8.
    • (2003) Circulation , vol.108 , pp. 2212-2218
    • Britten, M.B.1    Abolmaali, N.D.2    Assmus, B.3
  • 115
    • 0032419330 scopus 로고    scopus 로고
    • Stimulatory effects of neopterin on hematopoiesis in vitro are mediated by activation of stromal cell function
    • Aizawa S, Hiramoto M, Araki S, et al. Stimulatory effects of neopterin on hematopoiesis in vitro are mediated by activation of stromal cell function. Hematol Oncol 1998; 16: 57-67.
    • (1998) Hematol Oncol , vol.16 , pp. 57-67
    • Aizawa, S.1    Hiramoto, M.2    Araki, S.3
  • 116
    • 84934442804 scopus 로고    scopus 로고
    • Use of neopterin as a bone marrow hematopoietic and stromal cell growth factor in tissueengineered devices
    • Zvetkova E, Gluhcheva Y, Fuchs D. Use of neopterin as a bone marrow hematopoietic and stromal cell growth factor in tissueengineered devices. Adv Exp Med Biol 2006: 115-21.
    • (2006) Adv Exp Med Biol , pp. 115-121
    • Zvetkova, E.1    Gluhcheva, Y.2    Fuchs, D.3
  • 117
    • 72149120137 scopus 로고    scopus 로고
    • Neopterin
    • In: Thomas L, Ed., Frankfurt: TH Verlagsgesellschaft
    • Fuchs D, Wachter H. Neopterin. In: Thomas L, Ed. Clinical laboratory diagnostics. Frankfurt: TH Verlagsgesellschaft 1998; pp. 707-10.
    • (1998) Clinical laboratory diagnostics , pp. 707-710
    • Fuchs, D.1    Wachter, H.2
  • 118
    • 33645210851 scopus 로고    scopus 로고
    • Prognostic value of C-reactive protein and neopterin in autologous bone marrow cells transplantation
    • Shumakov V, Shevchenko O, Kazakov E, Orlova O, Gureev S, Makarova L. Prognostic value of C-reactive protein and neopterin in autologous bone marrow cells transplantation. Kardiologiia 2006; 46: 19-26.
    • (2006) Kardiologiia , vol.46 , pp. 19-26
    • Shumakov, V.1    Shevchenko, O.2    Kazakov, E.3    Orlova, O.4    Gureev, S.5    Makarova, L.6
  • 119
    • 33845494509 scopus 로고    scopus 로고
    • Inflammation and apoptosis in relation with the effectiveness of bone marrow cell transplantation to patients with chronic heart failure
    • Shumakov V, Shevchenko O, Orlova O, Onishchenko N, Gureev S. Inflammation and apoptosis in relation with the effectiveness of bone marrow cell transplantation to patients with chronic heart failure. Vestn Ross Akad Med Nauk 2006; 11: 14-21.
    • (2006) Vestn Ross Akad Med Nauk , vol.11 , pp. 14-21
    • Shumakov, V.1    Shevchenko, O.2    Orlova, O.3    Onishchenko, N.4    Gureev, S.5
  • 121
    • 0024308582 scopus 로고
    • Neopterin as marker for activation of cellular immunity: Immunologic basis and clinical application
    • Wachter H, Fuchs D, Hausen A, Reibnegger G, Werner E. Neopterin as marker for activation of cellular immunity: immunologic basis and clinical application. Adv Clin Chem 1989; 27: 81-141.
    • (1989) Adv Clin Chem , vol.27 , pp. 81-141
    • Wachter, H.1    Fuchs, D.2    Hausen, A.3    Reibnegger, G.4    Werner, E.5
  • 122
    • 0042162960 scopus 로고    scopus 로고
    • Potential role of immune system activation-associated production of neopterin derivatives in humans
    • Hoffmann G, Wirleitner B, Fuchs D. Potential role of immune system activation-associated production of neopterin derivatives in humans. Inflamm Res 2003; 8: 313-21.
    • (2003) Inflamm Res , vol.8 , pp. 313-321
    • Hoffmann, G.1    Wirleitner, B.2    Fuchs, D.3
  • 123
    • 0036223478 scopus 로고    scopus 로고
    • Pteridine derivatives as modulators of oxidative stress
    • Oettl K, Reibnegger G. Pteridine derivatives as modulators of oxidative stress. Curr Drug Metab 2002; 2: 203-9.
    • (2002) Curr Drug Metab , vol.2 , pp. 203-209
    • Oettl, K.1    Reibnegger, G.2
  • 124
    • 14644442283 scopus 로고    scopus 로고
    • Oxygen, oxidative stress, hypoxia, and heart failure
    • Giordano FJ. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Investig 2005; 115: 500-8.
    • (2005) J Clin Investig , vol.115 , pp. 500-508
    • Giordano, F.J.1
  • 125
    • 77949520673 scopus 로고    scopus 로고
    • Reactive oxygen species and antioxidants in the pathophysiology of cardiovascular disease: Does the actual knowledge justify a clinical approach?
    • De Rosa S, Cirillo P, Paglia A, Sasso L, Di Palma V, Chiariello M. Reactive oxygen species and antioxidants in the pathophysiology of cardiovascular disease: does the actual knowledge justify a clinical approach? Curr Vasc Pharmacol 2010; 8: 259-75.
    • (2010) Curr Vasc Pharmacol , vol.8 , pp. 259-275
    • De Rosa, S.1    Cirillo, P.2    Paglia, A.3    Sasso, L.4    Di Palma, V.5    Chiariello, M.6
  • 126
    • 0021209709 scopus 로고
    • Activation of human macrophages. Comparison of other cytokines with interferongamma
    • Nathan C, Prendergast T, Wiebe M, et al. Activation of human macrophages. Comparison of other cytokines with interferongamma. J Exp Med 1984; 2: 600-5.
    • (1984) J Exp Med , vol.2 , pp. 600-605
    • Nathan, C.1    Prendergast, T.2    Wiebe, M.3
  • 127
    • 0032823769 scopus 로고    scopus 로고
    • Antioxidant defence mechanisms: From the beginning to the end (of the beginning)
    • Halliwell B. Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Radic Res 1999; 4: 261-72.
    • (1999) Free Radic Res , vol.4 , pp. 261-272
    • Halliwell, B.1
  • 128
    • 0029562828 scopus 로고
    • Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells
    • Schobersberger W, Hoffmann G, Grote J, Wachter H, Fuchs D. Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells. FEBS Lett 1995; 377: 461-4.
    • (1995) FEBS Lett , vol.377 , pp. 461-464
    • Schobersberger, W.1    Hoffmann, G.2    Grote, J.3    Wachter, H.4    Fuchs, D.5
  • 129
    • 67649791102 scopus 로고    scopus 로고
    • Association between asymmetric dimethylarginine and neopterin in patients with and without angiographic coronary artery disease
    • Murr C, Meinitzer A, Grammer T, et al. Association between asymmetric dimethylarginine and neopterin in patients with and without angiographic coronary artery disease. Scand J Immunol 2009; 70: 63-7.
    • (2009) Scand J Immunol , vol.70 , pp. 63-67
    • Murr, C.1    Meinitzer, A.2    Grammer, T.3
  • 130
    • 33748746325 scopus 로고    scopus 로고
    • Neopterin induces proatherothrombotic phenotype in human coronary endothelial cells
    • Cirillo P, Pacileo M, De Rosa S, et al. Neopterin induces proatherothrombotic phenotype in human coronary endothelial cells. J Thromb Haemostas 2006; 4: 2248-55.
    • (2006) J Thromb Haemostas , vol.4 , pp. 2248-2255
    • Cirillo, P.1    Pacileo, M.2    De Rosa, S.3
  • 131
    • 0028226536 scopus 로고
    • Leucocyte-endothelial interactions and regulation of leucocyte migration
    • Adams D, Shaw S. Leucocyte-endothelial interactions and regulation of leucocyte migration. Lancet 1994; 8901: 831-6.
    • (1994) Lancet , vol.8901 , pp. 831-836
    • Adams, D.1    Shaw, S.2
  • 132
    • 0031004250 scopus 로고    scopus 로고
    • New indices of ischemic heart disease and aging: Studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhe sion molecule-1 (VCAM-1) in patients with hypercholesterolemia and ischemic heart disease
    • Morisaki N, Saito I, Tamura K, et al. New indices of ischemic heart disease and aging: studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhe sion molecule-1 (VCAM-1) in patients with hypercholesterolemia and ischemic heart disease. Atherosclerosis 1997; 131: 43-8.
    • (1997) Atherosclerosis , vol.131 , pp. 43-48
    • Morisaki, N.1    Saito, I.2    Tamura, K.3
  • 133
    • 0032501738 scopus 로고    scopus 로고
    • Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men
    • Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet 1998; 351: 88-92.
    • (1998) Lancet , vol.351 , pp. 88-92
    • Ridker, P.M.1    Hennekens, C.H.2    Roitman-Johnson, B.3    Stampfer, M.J.4    Allen, J.5
  • 134
    • 0027954408 scopus 로고
    • A monoclonal antibody against rabbit tissue factor inhibits thrombus formation in stenotic injured rabbit carotid arteries
    • Pawashe AB, Golino P, Ambrosio G, et al. A monoclonal antibody against rabbit tissue factor inhibits thrombus formation in stenotic injured rabbit carotid arteries. Circ Res 1994; 74: 56-63.
    • (1994) Circ Res , vol.74 , pp. 56-63
    • Pawashe, A.B.1    Golino, P.2    Ambrosio, G.3
  • 135
    • 9344230339 scopus 로고    scopus 로고
    • Monoclonal antibody against tissue factor shortens tissue plasminogen activator lysis time and prevents reocclusion in a rabbit model of carotid artery thrombosis
    • Ragni M, Cirillo P, Pascucci I, et al. Monoclonal antibody against tissue factor shortens tissue plasminogen activator lysis time and prevents reocclusion in a rabbit model of carotid artery thrombosis. Circulation 1996; 93: 1913-8.
    • (1996) Circulation , vol.93 , pp. 1913-1918
    • Ragni, M.1    Cirillo, P.2    Pascucci, I.3
  • 136
    • 0030570728 scopus 로고    scopus 로고
    • Neopterin activates transcription factor nuclear factor-[kappa]B in vascular smooth muscle cells
    • Hoffmann G, Schobersberger W, Frede S, et al. Neopterin activates transcription factor nuclear factor-[kappa]B in vascular smooth muscle cells. FEBS Lett 1996; 391: 181-4.
    • (1996) FEBS Lett , vol.391 , pp. 181-184
    • Hoffmann, G.1    Schobersberger, W.2    Frede, S.3
  • 137
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear Factor-_B - A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M. Nuclear Factor-_B - A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997; 336: 1066-71.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 138
    • 0030857071 scopus 로고    scopus 로고
    • Regulation of the tissue factor gene
    • Mackman N. Regulation of the tissue factor gene. Thromb Haemost 1997; 1: 747-54.
    • (1997) Thromb Haemost , vol.1 , pp. 747-754
    • Mackman, N.1
  • 139
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF- kappa B and cytokine-inducible enhancers
    • Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF- kappa B and cytokine-inducible enhancers. FASEB J 1995; 9: 899-909.
    • (1995) FASEB J , vol.9 , pp. 899-909
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 140
    • 0033392430 scopus 로고    scopus 로고
    • Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF- {kappa}B activation
    • Yan Z-q, Sirsjo A, Bochaton-Piallat M-L, Gabbiani G, Hansson GK. Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF- {kappa}B activation. Arterioscler Thromb Vasc Biol 1999; 19: 2854-62.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2854-2862
    • Yan, Z.-Q.1    Sirsjo, A.2    Bochaton-Piallat, M.-L.3    Gabbiani, G.4    Hansson, G.K.5
  • 141
    • 43149114461 scopus 로고    scopus 로고
    • Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage
    • Noguchi T, Ishii K, Fukutomi H, et al. Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J Biol Chem 2008; 283: 7657-65.
    • (2008) J Biol Chem , vol.283 , pp. 7657-7665
    • Noguchi, T.1    Ishii, K.2    Fukutomi, H.3
  • 142
    • 33644904306 scopus 로고    scopus 로고
    • Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice
    • Hsieh C-C, Papaconstantinou J. Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. FASEB J 2006; 20: 259-68.
    • (2006) FASEB J , vol.20 , pp. 259-268
    • Hsieh, C.-C.1    Papaconstantinou, J.2
  • 143
    • 59049090581 scopus 로고    scopus 로고
    • Mitochondrial complex iiigenerated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution
    • Soberanes S, Urich D, Baker CM, et al. Mitochondrial complex iiigenerated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. J Biol Chem 2009; 284: 2176-86.
    • (2009) J Biol Chem , vol.284 , pp. 2176-2186
    • Soberanes, S.1    Urich, D.2    Baker, C.M.3
  • 144
    • 23844435944 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1-mediated sustained p38 mitogen-activated protein kinase activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycantriggered Toll-like receptor 2 signalling pathways
    • Into T, Shibada K. Apoptosis signal-regulating kinase 1-mediated sustained p38 mitogen-activated protein kinase activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycantriggered Toll-like receptor 2 signalling pathways. Cell Microbiol 2005; 7: 1305-17.
    • (2005) Cell Microbiol , vol.7 , pp. 1305-1317
    • Into, T.1    Shibada, K.2


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