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Volumn 27, Issue 2, 2011, Pages 125-131

Innate immunity in the small intestine

Author keywords

IgA; innate immunity; nucleotide binding and oligomerization domain like receptor; Paneth cells; small intestine; toll like receptor

Indexed keywords

DEFENSIN; IMMUNOGLOBULIN A; INFLAMMASOME; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5;

EID: 79951675379     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e3283438dea     Document Type: Review
Times cited : (88)

References (51)
  • 1
    • 33646545649 scopus 로고    scopus 로고
    • CCR6(p) dendritic cells: The gut tactical-response unit
    • DOI 10.1016/j.immuni.2006.05.005, PII S1074761306002251
    • Rescigno M. CCR6(p) dendritic cells: the gut tactical-response unit. Immunity 2006; 24:508-510. (Pubitemid 43728161)
    • (2006) Immunity , vol.24 , Issue.5 , pp. 508-510
    • Rescigno, M.1
  • 3
    • 69949105213 scopus 로고    scopus 로고
    • Toll-like receptors (TLRs) and nod-like receptors (NLRs) in inflammatory disorders
    • Fukata M, Vamadevan AS, Abreu MT. Toll-like receptors (TLRs) and nod-like receptors (NLRs) in inflammatory disorders. Semin Immunol 2009; 21:242-253.
    • (2009) Semin Immunol , vol.21 , pp. 242-253
    • Fukata, M.1    Vamadevan, A.S.2    Abreu, M.T.3
  • 5
    • 69449102284 scopus 로고    scopus 로고
    • Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors
    • Fukata M, Hernandez Y, Conduah D, et al. Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors. Inflamm Bowel Dis 2009; 15:997-1006.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 997-1006
    • Fukata, M.1    Hernandez, Y.2    Conduah, D.3
  • 6
    • 48549103766 scopus 로고    scopus 로고
    • Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria
    • Shang L, Fukata M, Thirunarayanan N, et al. Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology 2008; 135:529-538.
    • (2008) Gastroenterology , vol.135 , pp. 529-538
    • Shang, L.1    Fukata, M.2    Thirunarayanan, N.3
  • 7
    • 3242692641 scopus 로고    scopus 로고
    • Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
    • DOI 10.1053/j.gastro.2004.04.015, PII S0016508504007103
    • Cario E, Gerken G, Podolsky DK. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology 2004; 127:224-238. (Pubitemid 38962290)
    • (2004) Gastroenterology , vol.127 , Issue.1 , pp. 224-238
    • Cario, E.1    Gerken, G.2    Podolsky, D.K.3
  • 8
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 2010; 10:159-169.
    • (2010) Nat Rev Immunol , vol.10 , pp. 159-169
    • Hooper, L.V.1    MacPherson, A.J.2
  • 9
    • 17044385039 scopus 로고    scopus 로고
    • TLR signaling in the gut in health and disease
    • Abreu MT, Fukata M, Arditi M. TLR signaling in the gut in health and disease. J Immunol 2005; 174:4453-4460.
    • (2005) J Immunol , vol.174 , pp. 4453-4460
    • Abreu, M.T.1    Fukata, M.2    Arditi, M.3
  • 10
    • 75649093343 scopus 로고    scopus 로고
    • Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function
    • Abreu MT. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol 2010; 10:131-144.
    • (2010) Nat Rev Immunol , vol.10 , pp. 131-144
    • Abreu, M.T.1
  • 11
    • 77953482525 scopus 로고    scopus 로고
    • Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation
    • Smythies LE, Shen R, Bimczok D, et al. Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation. J Biol Chem 2010; 285:19593-19604.
    • (2010) J Biol Chem , vol.285 , pp. 19593-19604
    • Smythies, L.E.1    Shen, R.2    Bimczok, D.3
  • 12
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Cause and immunobiology
    • DOI 10.1016/S0140-6736(07)60750-8, PII S0140673607607508
    • Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007; 369:1627-1640. (Pubitemid 46722636)
    • (2007) Lancet , vol.369 , Issue.9573 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 14
    • 1342344961 scopus 로고    scopus 로고
    • Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors
    • DOI 10.1128/IAI.72.3.1487-1495.2004
    • Kim JG, Lee SJ, Kagnoff MF. Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun 2004; 72:1487-1495. (Pubitemid 38263771)
    • (2004) Infection and Immunity , vol.72 , Issue.3 , pp. 1487-1495
    • Kim, J.G.1    Lee, S.J.2    Kagnoff, M.F.3
  • 15
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • DOI 10.1038/nature07450, PII NATURE07450
    • Bouskra D, Brezillon C, Berard M, et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008; 456:507-510. (Pubitemid 352759006)
    • (2008) Nature , vol.456 , Issue.7221 , pp. 507-510
    • Bouskra, D.1    Brezillon, C.2    Berard, M.3    Werts, C.4    Varona, R.5    Boneca, I.G.6    Eberl, G.7
  • 19
    • 70349468054 scopus 로고    scopus 로고
    • Nod2 is required for the regulation of commensal microbiota in the intestine
    • Petnicki-Ocwieja T, Hrncir T, Liu YJ, et al. Nod2 is required for the regulation of commensal microbiota in the intestine. Proc Natl Acad Sci U S A 2009; 106:15813-15818.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15813-15818
    • Petnicki-Ocwieja, T.1    Hrncir, T.2    Liu, Y.J.3
  • 20
    • 77149169405 scopus 로고    scopus 로고
    • Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
    • Barreau F, Madre C, Meinzer U, et al. Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut 2010; 59:207-217.
    • (2010) Gut , vol.59 , pp. 207-217
    • Barreau, F.1    Madre, C.2    Meinzer, U.3
  • 21
    • 64049096349 scopus 로고    scopus 로고
    • Sensing pathogens and danger signals by the inflammasome
    • Pedra JH, Cassel SL, Sutterwala FS. Sensing pathogens and danger signals by the inflammasome. Curr Opin Immunol 2009; 21:10-16.
    • (2009) Curr Opin Immunol , vol.21 , pp. 10-16
    • Pedra, J.H.1    Cassel, S.L.2    Sutterwala, F.S.3
  • 23
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: A caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 2009; 10:241-247.
    • (2009) Nat Immunol , vol.10 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Munoz-Planillo, R.3    Nunez, G.4
  • 24
    • 58149159542 scopus 로고    scopus 로고
    • Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
    • Villani A-C, Lemire M, Fortin G, et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet 2009; 41:71-76.
    • (2009) Nat Genet , vol.41 , pp. 71-76
    • Villani, A.-C.1    Lemire, M.2    Fortin, G.3
  • 25
    • 66949174089 scopus 로고    scopus 로고
    • Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
    • Schoultz I, Verma D, Halfvarsson J, et al. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am J Gastroenterol 2009; 104:1180-1188.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1180-1188
    • Schoultz, I.1    Verma, D.2    Halfvarsson, J.3
  • 26
    • 79951670887 scopus 로고    scopus 로고
    • Genetic association between NLRP3 variants and Crohn's disease does not replicate in a large UK panel
    • [Epub ahead of print]
    • Lewis GJ, Massey DCO, Zhang H, et al. Genetic association between NLRP3 variants and Crohn's disease does not replicate in a large UK panel. Inflammatory Bowel Dis 2010 [Epub ahead of print].
    • (2010) Inflammatory Bowel Dis
    • Lewis, G.J.1    Massey, D.C.O.2    Zhang, H.3
  • 27
    • 77953122347 scopus 로고    scopus 로고
    • Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease
    • Roberts RL, Topless RKG, Phipps-Green AJ, et al. Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease. Genes Immun 2010; 11:351-356.
    • (2010) Genes Immun , vol.11 , pp. 351-356
    • Roberts, R.L.1    Rkg, T.2    Phipps-Green, A.J.3
  • 30
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • Hapfelmeier S, Lawson MA, Slack E, et al. Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science 2010; 328:1705-1709.
    • (2010) Science , vol.328 , pp. 1705-1709
    • Hapfelmeier, S.1    Lawson, M.A.2    Slack, E.3
  • 31
    • 0034252293 scopus 로고    scopus 로고
    • Secretion of microbicidal [alpha]-defensins by intestinal Paneth cells in response to bacteria
    • Ayabe T, Satchell DP, Wilson CL, et al. Secretion of microbicidal [alpha]-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 2000; 1:113-118.
    • (2000) Nat Immunol , vol.1 , pp. 113-118
    • Ayabe, T.1    Satchell, D.P.2    Wilson, C.L.3
  • 32
    • 75749133608 scopus 로고    scopus 로고
    • Bacterial flagellin stimulates toll-like receptor 5-dependent defense against vancomycin-resistant enterococcus infection
    • KinnebrewM, Ubeda C, Zenewicz L, et al. Bacterial flagellin stimulates toll-like receptor 5-dependent defense against vancomycin-resistant enterococcus infection. J Infect Dis 2010; 201:534-543.
    • (2010) J Infect Dis , vol.201 , pp. 534-543
    • Kinnebrew, M.1    Ubeda, C.2    Zenewicz, L.3
  • 35
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • DOI 10.1126/science.1127119
    • Cash HL, Whitham CV, Behrendt CL, Hooper LV. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 2006; 313:1126-1130. (Pubitemid 44300239)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 36
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • Vaishnava S, Behrendt CL, Ismail AS, et al. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A 2008; 105:20858-20863.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3
  • 37
    • 77954314592 scopus 로고    scopus 로고
    • Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation
    • Gong J, Xu J, Zhu W, et al. Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation. Clin Immunol 2010; 136:245-256.
    • (2010) Clin Immunol , vol.136 , pp. 245-256
    • Gong, J.1    Xu, J.2    Zhu, W.3
  • 41
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008; 456:259-263.
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3
  • 42
    • 61649114427 scopus 로고    scopus 로고
    • A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn's disease
    • Cadwell K, Patel KK, Komatsu M, et al. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn's disease. Autophagy 2009; 5:250-252.
    • (2009) Autophagy , vol.5 , pp. 250-252
    • Cadwell, K.1    Patel, K.K.2    Komatsu, M.3
  • 43
    • 73849121209 scopus 로고    scopus 로고
    • Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
    • Travassos LH, Carneiro LAM, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11:55-62.
    • (2010) Nat Immunol , vol.11 , pp. 55-62
    • Travassos, L.H.1    Carneiro, L.A.M.2    Ramjeet, M.3
  • 44
    • 78649424618 scopus 로고    scopus 로고
    • Interleukin-17A is required to suppress invasion of Salmonella enterica serovar Typhimurium to enteric mucosa
    • Mayuzumi H, Inagaki-Ohara K, Uyttenhove C, et al. Interleukin-17A is required to suppress invasion of Salmonella enterica serovar Typhimurium to enteric mucosa. Immunology 2010; 131:377-385.
    • (2010) Immunology , vol.131 , pp. 377-385
    • Mayuzumi, H.1    Inagaki-Ohara, K.2    Uyttenhove, C.3
  • 45
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17p T helper cells
    • DOI 10.1016/j.cell.2006.07.035, PII S0092867406011056
    • Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17p T helper cells. Cell 2006; 126:1121-1133. (Pubitemid 44380299)
    • (2006) Cell , vol.126 , Issue.6 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 46
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar M, Aitken JD, Carvalho FA, et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010; 328:228-231.
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3
  • 47
    • 74049093945 scopus 로고    scopus 로고
    • Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut
    • Wolfs TG, Derikx JP, Hodin CM, et al. Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut. Inflamm Bowel Dis 2010; 16:68-75.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 68-75
    • Wolfs, T.G.1    Derikx, J.P.2    Hodin, C.M.3
  • 48
    • 77956159711 scopus 로고    scopus 로고
    • Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium
    • e1-e6
    • Richardson WM, Sodhi CP, Russo A, et al. Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium. Gastroenterology 2010; 139:904-917; e1-e6.
    • (2010) Gastroenterology , vol.139 , pp. 904-917
    • Richardson, W.M.1    Sodhi, C.P.2    Russo, A.3
  • 49
    • 70449387225 scopus 로고    scopus 로고
    • Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar Typhimurium infection, but not for the initiation of bacterial clearance
    • Talbot S, Tötemeyer S, Yamamoto M, et al. Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar Typhimurium infection, but not for the initiation of bacterial clearance. Immunology 2009; 128:472-483.
    • (2009) Immunology , vol.128 , pp. 472-483
    • Talbot, S.1    Tötemeyer, S.2    Yamamoto, M.3
  • 50
    • 34548597000 scopus 로고    scopus 로고
    • Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif
    • DOI 10.1111/j.1365-2567.2007.02631.x
    • Cook P, Tötemeyer S, Stevenson C, et al. Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif. Immunology 2007; 122:222-229. (Pubitemid 47389950)
    • (2007) Immunology , vol.122 , Issue.2 , pp. 222-229
    • Cook, P.1    Totemeyer, S.2    Stevenson, C.3    Fitzgerald, K.A.4    Yamamoto, M.5    Akira, S.6    Maskell, D.J.7    Bryant, C.E.8


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