Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: Tunneling in the substrate backbone as well as the transferred hydrogen

Journal of the American Chemical Society

Volumn 133, Issue 3, 2011, Pages 430-439

  Meyer, Matthew P ^a,b   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-H BOND CLEAVAGE; CARBON-13; CLEAVAGE REACTION; DEUTERIUM ISOTOPE EFFECT; ELECTRON TRANSFER; ELECTRONIC EFFECTS; EXPERIMENTAL VALUES; FORCE CONSTANTS; ISOTOPE EFFECT; KINETIC ISOTOPE EFFECTS; NONCLASSICAL BEHAVIOR; QUANTUM MECHANICAL METHOD; SOYBEAN LIPOXYGENASE; TORSIONAL STRAIN;

DEUTERIUM; HYDROGEN; LINOLEIC ACID; QUANTUM THEORY; SPHERES;

CARRIER MOBILITY;

CARBON 13; HYDROGEN; LIPOXYGENASE;

ARTICLE; CHEMICAL BINDING; ELECTRON TRANSPORT; KINETICS; SOYBEAN;

CATALYSIS; HYDROGEN; KINETICS; LIPOXYGENASE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; SOYBEANS;

EID: 79851479815     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1050742     Document Type: Article

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