Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: Evidence for hydrogen tunneling, coupled motion, and similar reactivities

Journal of the American Chemical Society

Volumn 127, Issue 47, 2005, Pages 16414-16415

  Pavon, Jorge Alex ^a   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; AROMATIC AMINO ACID HYDROXYLASE DERIVATIVE; HYDROGEN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME MECHANISM; HYDROXYLATION; KINETICS; QUANTUM MECHANICS; TEMPERATURE DEPENDENCE;

BENZENE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEUTERIUM; HYDROXYLATION; MOLECULAR STRUCTURE; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; TYROSINE 3-MONOOXYGENASE;

EID: 28444448357     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0562651     Document Type: Article

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