Experimental evidence for enzyme-enhanced coupled motion/quantum mechanical hydrogen tunneling by ketosteroid isomerase

Journal of the American Chemical Society

Volumn 130, Issue 20, 2008, Pages 6577-6585

  Wilde, Thomas C ^a   Blotny, Grzegorz ^a   Pollack, Ralph M ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; ELECTRON TRANSPORT PROPERTIES; ENZYMES; ISOMERIZATION; RATE CONSTANTS; REACTION KINETICS;

ENZYMATIC REACTION; HYDROGEN TUNNELING (HT); KINETIC ISOTOPE EFFECTS (KIE); NONENZYMATIC SYSTEMS;

ELECTRON TUNNELING;

ACETIC ACID; ANDROSTENEDIOL; ANDROSTENEDIONE; DEUTERIUM; HYDROGEN; STEROID DELTA ISOMERASE;

ARTICLE; AUTOOXIDATION; CATALYSIS; ENZYME MECHANISM; HYDROGEN BOND; ISOMERIZATION; MUTATION; QUANTUM MECHANICS;

ANDROSTENES; CATALYSIS; DEUTERIUM; HYDROGEN; ISOMERISM; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; OXIDATION-REDUCTION; QUANTUM THEORY; STEROID ISOMERASES; THERMODYNAMICS;

EID: 43949138259     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0732330     Document Type: Article

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